scholarly journals Accepting Immunotherapy After Multiline Treatment Failure: An Exploration of the Anxiety and Depression in Patients with Advanced Cancer Experience

2022 ◽  
Vol Volume 16 ◽  
pp. 1-9
Author(s):  
Qingqing Xie ◽  
Caixia Sun ◽  
Zhenghua Fei ◽  
Xujing Yang
Keyword(s):  
Treatment Failure ◽  
Advanced Cancer ◽  
Anxiety And Depression ◽  
Cancer Experience

scholarly journals A qualitative investigation of influencing factors for anxiety and depression in patients with advanced cancer after multiline treatment failure

2020 ◽  
Author(s):  
Xujing Yang ◽  
Qingqing Xie ◽  
Caixia Sun ◽  
Zhenghua Fei
Keyword(s):  
Treatment Failure ◽  
Influencing Factors ◽  
Advanced Cancer ◽  
Medical Staff ◽  
Depression Scale ◽  
Psychological Needs ◽  
Anxiety And Depression ◽  
Related Factors ◽  
Programmed Death ◽  
Before And After

Abstract Background: To investigate the anxiety and depression of patients with advanced cancer who received immunotherapy using programmed death-1 or programmed death-ligand 1 after multiline treatment failure, to explore the influencing factors, and to provide reference for clinical medical staff and psychological support for patients.Methods: The Hospital Anxiety and Depression Scale was used to calculate the anxiety and depression scores before and after 1, 2 and 3 courses of treatment, respectively. The patients with anxiety and depression were counted. Purposive sampling was used to conduct face-to-face semi-structured interviews with 21 patients to find out the reasons. The obtained data were analyzed and collated using the Colaizzi's phenomenological method.Results: Before and after 1, 2 and 3 courses of treatment, 18.26%, 23.0%, 50% and 54% of patients suffered from anxiety and depression, respectively. Four related factors, i.e. low expectations for immunotherapy, lack of timely information after treatment, lack of awareness of treatment and drugs, and lack of family and social support, were extracted with the sampling survey. The proportion of patients with anxiety and depression during immunotherapy kept increasing.Conclusion: The anxiety and depression of patients with advanced cancer who receive immunotherapy after multiline treatment failure are aggravated along with treatment. Patients need to be given humane care and emotional support from their families, society and medical staff. Nursing staff should adopt personalized measures to meet the psychological needs of patients, and a targeted and complete nursing system should be established to extend the life span and to improve the quality of life.Trial registration: ChiCTR, ChiCTR1800015942. Registered 1 May 2018, http://www.chictr.org.cn/showproj.aspx?proj=26476

scholarly journals Family caregiver emotional distress in advanced cancer: the DME-C scale psychometric properties

2020 ◽  
pp. bmjspcare-2020-002608
Author(s):  
Joaquín T Limonero ◽  
Jorge Maté-Méndez ◽  
María José Gómez-Romero ◽  
Dolors Mateo-Ortega ◽  
Jesús González-Barboteo ◽  
...  
Keyword(s):  
Psychometric Properties ◽  
End Of Life ◽  
Family Caregivers ◽  
Advanced Cancer ◽  
Emotional Distress ◽  
Family Caregiver ◽  
Screening Tools ◽  
Anxiety And Depression ◽  
The Family ◽  
End Stage

BackgroundFamily caregivers of patients with advanced illness at end of life often report high levels of emotional distress. To address this emotional distress is necessary to have adequate and reliable screening tools.AimThis study analyses the psychometric properties and clinical utility of the Family Caregiver Emotional Detection Scale for caregivers of patients with end-stage cancer (DME-C, Spanish acronym) who are receiving palliative care (PC).DesignMulticentre, cross-sectional study.Settings/participantsFamily caregivers of patients with advanced cancer at end of life receiving palliative treatment were interviewed to explore their emotional distress through the DME-C scale and other instruments measuring anxiety and depression (Hospital Anxiety and Depression Scale (HADS)), distress thermometer (DT) and overload (B), as well as a clinical psychological assessment (CPA).Results138 family caregivers, 85 (61.6%) female and 53 (38.4%) male, with an average age of 59.69±13.3 participated in the study. The reliability of the scale, as measured by Cronbach’s alpha, was 0.76, and its stability over time was 0.734. Positive, significant correlations were found between the DME-C and the scores for anxiety and depression registered on the HADS scale, as well as with the total result of this latter scale and the results for B, the DT and the CPA. A statistical analysis of the receiver-operating characteristic curves showed that the scale has a sensitivity and specificity of 75%, and that the cut-off point for the detection of emotional distress was a score ≥11. Fifty-four per cent of the caregivers displayed emotional distress according to this scale.ConclusionsThe DME-C displays good psychometric properties. It is simple, short, reliable and easy to administer. We believe that the instrument is useful for the detection of emotional distress in the family caregivers of hospitalised patients suffering from end-stage illnesses and receiving PC.

Abstract 42: Patient-Provider Communication in the Setting of Advanced Cancer: Experience and Views from Rwanda

2021 ◽  
Author(s):  
Pacifique Uwamahoro ◽  
Hubert Tuyishime ◽  
Vincent Cubaka ◽  
Egide Mpanumusingo ◽  
Anita Ho ◽  
...  
Keyword(s):  
Advanced Cancer ◽  
Provider Communication ◽  
Patient Provider Communication ◽  
Cancer Experience

Coping styles and psychological outcomes in men with advanced cancer

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e20521-e20521
Author(s):  
K. Schmidt ◽  
P. Monahan ◽  
Y. Tong ◽  
S. Rawl ◽  
K. Rand ◽  
...  
Keyword(s):  
Advanced Cancer ◽  
Coping Styles ◽  
Pearson Correlation ◽  
Depression Scale ◽  
Correlation Coefficients ◽  
Psychological Outcomes ◽  
Anxiety And Depression ◽  
Anxiety State ◽  
Post Traumatic Growth ◽  
Post Traumatic

e20521 Background: The psychological outcomes of men with advanced cancer may vary based upon their appraisal and response to the threat of cancer. Coping styles in other illnesses are influenced by gender and stage of disease, but little is known specifically about men with advanced cancer. Methods: We recruited 81 men with advanced cancer to complete surveys assessing coping (Mini-MAC), post-traumatic growth (PTGI), and psychological outcomes (Hospital Anxiety and Depression Scale). Psychological outcomes and coping styles were determined with means, and percentages above established cutoff points. Relationships were assessed using Pearson correlation coefficients. Results: The mean HADS anxiety and depression scores were 5.4 and 4.0, respectively. Fourteen men (17%) scored 8–10 and 8 (10%) scored ≥11 suggesting an anxiety state and disorder, respectively. Eight men (10%) had scores suggesting a depressive state and 4 (5%) a depressive disorder. Greater helplessness/hopelessness and anxious preoccupation scores were correlated with greater anxiety (r =.54, p<.0001; r =.66, p<.0001) and depression scores (r =.43, p<.0001; r=.47, p<.0001). Greater fighting spirit correlated with less anxiety (r =-.26, p=.018) and less depression (r = -.42, p < .0001) and with increased post-traumatic growth in the form of new possibilities (r = .26, p = .020), personal strength (r = .33, p = .003), and the total PTGI score (r = .23, p = .043). Greater fatalism was associated with lower total distress measured by the total HADS score (r = -.24, p = .032), and marginally so when assessed separately for anxiety (r = -.22, p = .052) and depression (r = -.21, p = .056). In addition, greater fatalism was significantly associated with greater post-traumatic growth in all five areas assessed by the PTGI subscales (.27 < r < .36; .001 p < .032). Conclusions: As expected men with advanced cancer report anxiety and depression. Coping styles were significantly associated with anxiety, depression, and post-traumatic growth. No significant financial relationships to disclose.

Benefits of immediate versus delayed palliative care to informal family caregivers of persons with advanced cancer: Outcomes from the ENABLE III randomized clinical trial.

2014 ◽  
Vol 32 (18_suppl) ◽  
pp. LBA9513-LBA9513 ◽  
Author(s):  
J Nicholas Dionne-Odom ◽  
Andres Azuero ◽  
Kathleen Lyons ◽  
Zhongze Li ◽  
Tor Tosteson ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Palliative Care ◽  
Randomized Clinical Trial ◽  
Family Caregivers ◽  
Advanced Cancer ◽  
Treatment Effects ◽  
Subjective Burden ◽  
Patient Death ◽  
Burden Scale ◽  
Cancer Experience

LBA9513 Background: Family caregivers of individuals with advanced cancer experience significant burden and diminished QOL; few interventions have been found to reduce these outcomes. Methods: Randomized clinical trial conducted from 10/11/2010 to 9/5/2013 of immediate versus delayed (initiated 12 weeks after randomization) entry patients (n=207) and caregivers (n=122) into ENABLE (Educate, Nurture, Advise, Before Life Ends), a phone-based concurrent oncology palliative care intervention. QOL (Caregiver Quality of Life-Cancer, lower scores=better QOL), depression (Center for Epidemiological Study-Depression) and burden (Montgomery Borgatta Caregiver Burden Scale; subjective burden [SB], objective burden [OB]; demand burden [DB]) measures were collected at baseline, 6, 12, 18, and 24 weeks, and every 12 weeks until patient death or study completion. Results: Estimated treatment effects (immediate minus delayed) for caregivers from randomization to 12 weeks were (mean [SE]): -3.1 [2.3] for QOL (P=.17), -4.1 [1.3] for depression (P=.003), -1.0 [0.4] for SB (P=.02), 0.3 [0.6] for OB (P=.60), and -0.5 [0.6] for DB (P=.39). Estimated treatment effects (immediate minus delayed) from intervention initiation to 12 weeks were (mean [SE]): -6.4 [3.4] for QOL (P=.06), -7.4 [2] for depression (P<.001), -1.0 [0.6] for SB (P=.08), -0.6 [0.7] for OB (P=.44), and -0.5 [0.8] for DB (P=.50). Estimated treatment effects (immediate minus delayed) measured backwards from the time of patient’s death were (mean [SE]): of -4.9 [2.6] for QOL (P=.07), -3.8 [1.5] for depression (P=.02), -1.1 [0.4] for SB (P=.01), -0.6 [0.6] for OB (P=.26), and -0.7 [0.6] for DB (P=.22). Conclusions: Caregivers in the immediate group had lower depression, SB, and trends towards better QOL in comparisons up to 12 weeks, following initiation of the intervention in both groups, and in the terminal decline analysis. These results suggest that concurrent oncology palliative care should be initiated as early as possible to maximize benefit to caregivers. Clinical trial information: NCT01245621.

Symptom distress in advanced cancer patients with anxiety and depression in the palliative care setting

2008 ◽  
Vol 17 (5) ◽  
pp. 573-579 ◽  
Author(s):  
Marvin Delgado-Guay ◽  
Henrique A. Parsons ◽  
Zhijun Li ◽  
J. Lynn Palmer ◽  
Eduardo Bruera
Keyword(s):  
Palliative Care ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Care Setting ◽  
Symptom Distress ◽  
Anxiety And Depression ◽  
Advanced Cancer Patients ◽  
Palliative Care Setting

scholarly journals Experiences with scans and scanxiety in people with advanced cancer: A qualitative study

2021 ◽  
Author(s):  
Kim Tam Bui ◽  
Prunella Blinman ◽  
Belinda E Kiely ◽  
Chris Brown ◽  
Haryana M Dhillon
Keyword(s):  
Advanced Cancer ◽  
Quantitative Research ◽  
Qualitative Interviews ◽  
Clinical Problem ◽  
Framework Analysis ◽  
Cancer Data ◽  
Normal Part ◽  
Cancer Experience ◽  
And Coping ◽  
Common Clinical Problem

Abstract Purpose: Scan-associated anxiety (‘scanxiety’) in people with advanced cancer is a common clinical problem. This study aims to explore the experiences of scans and scanxiety in people with advanced cancer, including their strategies to reduce scanxiety.Methods: Semi-structured qualitative interviews were conducted with people with advanced cancers who had a computed tomography scan for monitoring of their cancer. Data was analysed with an interpretivist approach using framework analysis. Results: Interviews with 16 participants identified three key themes: the scan experience, the scanxiety experience and coping with scans. Scans and scanxiety were viewed as a routine and normal part of cancer care, though this was experienced differently by each person. Scanxiety often related to the scan result rather than the scan, and lead to psycho-cognitive manifestations. Adaptive coping strategies were often self-derived.Conclusion: People with advanced cancer experience scanxiety, but often accept scanxiety as a normal part of the cancer process. The findings fit within a transactional model of stress and coping, which influences the level of scanxiety for each individual. Quantitative research to determine the scope of scanxiety will be useful to develop formal approaches to reduce scanxiety.

scholarly journals 1494P Anxiety and depression during the COVID-19 pandemic in newly diagnosed advanced cancer patients

2021 ◽  
Vol 32 ◽  
pp. S1098
Author(s):  
B. Obispo ◽  
R. Hernandez ◽  
P. Cruz ◽  
A. Fernandez Montes ◽  
M. Gil Raga ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Advanced Cancer ◽  
Anxiety And Depression ◽  
Newly Diagnosed ◽  
Advanced Cancer Patients

scholarly journals Evaluation of self abilities among people with advanced cancer

2020 ◽  
Vol 11 (4) ◽  
pp. 6564-6566
Author(s):  
Ganapathy Sankar U ◽  
Monisha R
Keyword(s):  
Advanced Cancer ◽  
Sense Of Self ◽  
Treatment Options ◽  
The Self ◽  
Theory Approach ◽  
Advanced Stages ◽  
Living With Cancer ◽  
Cancer Experience ◽  
Evaluation Of Data ◽  
Grounded Theory Approach

Living with cancer can have adverse effects on the self. Various factors affect the person self in daily life. It is well documented that encouragement can provide hope and engagement for a person with cancer to engage in his activities of daily living. The support of family and friends helps the persons to lead his life along with the illness. Cancer rehabilitation is a rapidly evolving field all over the world, in large part because of increases in the number of cancer survivors. Everybody wishes to restore the function as resume their lives as usual. Few argue with the rehabilitation experts that treatment options differ from country to country, and does it affect the survival rate? Little research is done to explore how the self of the person suffering in advanced stages of cancer, and we aim to evaluate how people with cancer experience their sense of self. Thirty interviews were conducted with ten patients with advanced cancer, and grounded theory approach was used for statistical evaluation of data. Accepting self and reassessing self was the result of engaging the person in a specific occupation, which is considered to have a core in rehabilitating the person with advanced cancer. Engagement towards occupation influence the self of a person with advanced cancer.

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