scholarly journals Connective tissue dysplasia: a risk factor for osteopenia in children and adolescents

2020 ◽  
pp. 30-40
Author(s):  
I. N. Zakharova ◽  
T. M. Tvorogova ◽  
E. А. Solov’yeva ◽  
L. L. Stepurina ◽  
A. S. Vorob’yeva
Keyword(s):  
Risk Factor ◽  
Connective Tissue ◽  
Children And Adolescents ◽  
Connective Tissue Dysplasia

scholarly journals Auscultatory manifestations of mitral valve prolapse in children with connective tissue dysplasia

2012 ◽  
Vol 93 (4) ◽  
pp. 570-575
Author(s):  
Sh M Magomedova ◽  
Yu M Belozerov ◽  
K A Masuev ◽  
I M Osmanov
Keyword(s):  
Mitral Valve ◽  
Connective Tissue ◽  
Children And Adolescents ◽  
Mitral Valve Prolapse ◽  
Control Group ◽  
Ehlers Danlos Syndrome ◽  
Psychoemotional Stress ◽  
Connective Tissue Dysplasia ◽  
Cardiac Pain ◽  
Leaflet Prolapse

Aim. To study the features of auscultatory symptoms in children with mitral valve prolapse secondary to connective tissue dysplasia. Methods. Auscultation and phonocardiography was performed in 545 children and adolescents with mitral valve prolapse, including a prolapse, which is a variant of the asthenic constitution - 140, with a prolapse with undifferentiated connective tissue dysplasia - 340, with mitral valve prolapse with differentiated connective tissue dysplasia - 65 children (patients with Marfan syndrome and Ehlers-Danlos syndrome). The control group consisted of 200 children and adolescents of similar age. Results. In children with an asthenic constitution and mitral valve prolapse in most cases (90.7%) established were isolated clicks, and only iin a small percentage of cases the clicks combined with the late systolic murmur. Complaints of these children did not differ significantly in the frequency from the control values. Compared with the control group up to 6 times more frequently found was the symptom of chronic psychoemotional stress. Chronic psychoemotional stress was also observed more frequently in adolescents with mitral valve prolapse in the background of undifferentiated and differentiated connective tissue dysplasia. Children with asthenic constitution the frequency of cardiac pain did not differ from the control values. A significant increase in the frequency of cardialgia was reported in children and adolescents with undifferentiated and differentiated connective tissue dysplasia. Cardiac pain was described as stabbing, pressing, aching, and was felt in the left side of the chest without irradiation. In most children the pain continued for 5-20 min, were usually enduced by physical exertion and emotional stress, often accompanied by autonomic disturbances, which resolved spontaneously or after administration of the tincture of valerian or valokordin. The absence of ischemic changes in the myocardium according to the comprehensive investigation can be regarded as a manifestation of cardialgia as a sympathalgia related to psychoemotional features of children with mitral valve prolapse («cardiac pain is inseparable from the personality»). The auscultatory pattern suring mitral valve prolapse in the background of undifferentiated and differentiated connective tissue dysplasia was very similar. Conclusion. According to the phonocardiography and auscultatory data we can conclude that there is a certain parallelism of the severity of valve leaflet prolapse and of the sound phenomena: in isolated clicks the leaflet prolapse degree is usually minor, however in cases of isolated late systolic and holosystolic murmurs - the prolapse degree is significant.

scholarly journals Connective tissue dysplasia as a risk factor complicated course of surgical diseases knee in children

2016 ◽  
Vol 11 (2) ◽  
Author(s):  
Vladimir Murga ◽  
Vladimir Krestyashin ◽  
Leonid Rasskazov ◽  
Galina Rumyantseva ◽  
Vladimir Kartashev
Keyword(s):  
Risk Factor ◽  
Connective Tissue ◽  
Complicated Course ◽  
Connective Tissue Dysplasia

scholarly journals Connective tissue dysplasia syndrome as a risk factor of severe course of bronchial obstruction syndrome in children

2016 ◽  
Vol 11 (4) ◽  
Author(s):  
Natalia Fedko ◽  
Angelina Kalmykova ◽  
Natalia Lagodina ◽  
Valentina Muravyeva ◽  
Asiyat Dzhanibekova ◽  
...  
Keyword(s):  
Risk Factor ◽  
Connective Tissue ◽  
Bronchial Obstruction ◽  
Connective Tissue Dysplasia

scholarly journals Undifferentiated connective tissue dysplasia as a predictor of heart rate disorders in combination with gastroesophageal reflux disease in children

2021 ◽  
pp. 41-45
Author(s):  
Oksana Herasymova ◽  
Tetiana Filonova
Keyword(s):  
Risk Factor ◽  
Gastroesophageal Reflux Disease ◽  
Connective Tissue ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Study Groups ◽  
Group Iii ◽  
Group I ◽  
Connective Tissue Dysplasia ◽  
Tooth Growth

The aim: to improve the early diagnosis of arrhythmia in combination with gastroesophageal reflux disease (GERD) in children, by studying the risk of connective tissue dysplasia on the occurrence of this pathology. Materials and methods. We examined 100 children aged 8 to 18 years, mean age 13.7±2.7 years, of which 32 children with arrhythmias without combined pathology were group I, 36 children with concomitant GERD - group II and 32 children with GERD without concomitant arrhythmias - group III. Patients underwent clinical and instrumental studies (electrocardiography, Holter daily ECG monitoring, esophagogastroduodenoscopy and pH-metry) and evaluation of phenotypic signs of NDST according to the criteria of T. Milkovskaya-Dimitrova and A. Karkasho. Results. A risk factor for the formation of combined pathology in children in the form of arrhythmia and GERD was identified, namely the next main phenotypic feature of NDST (undifferentiated connective tissue dysplasia) – dysplastic tooth growth. Also, predictors of both an isolated variant of arrhythmia in children and arrhythmia in combination with GERD – high height and scoliotic posture were identified. In this case, the risk factor for an isolated variant of arrhythmia in children, according to the results of the study is asthenic constitution. The severity of NDST in the studied groups was determined. The analysis of the results revealed the absence of a statistically significant relationship between the severity of NDST and study groups, although it should be noted that in children of group III the first degree of NDST was not observed in general. Conclusions. It was found that asthenic constitution, dysplastic tooth growth, tall stature and scoliotic posture are statistically significant risk factors for the development of the studied pathologies. There were no statistically significant differences between the study groups regarding the severity of NDST, but there was a complete lack of detection in children of group III (children with isolated GERD without concomitant arrhythmia) of the first degree of NDST

scholarly journals CONNECTIVE TISSUE DYSPLASIA AS A POTENTIAL RISK FACTOR FOR MYOCARDIAL ELECTRIC INSTABILITY IN YOUNG ATHLETES

2020 ◽  
Vol 19 (4) ◽  
pp. 125-132 ◽  
Author(s):  
V Timokhina ◽  
K Mekhdieva ◽  
F Blyakhman
Keyword(s):  
Risk Factor ◽  
Connective Tissue ◽  
Respiratory System ◽  
Recovery Time ◽  
Stress Test ◽  
Physical Exertion ◽  
National Guidelines ◽  
Young Athletes ◽  
System Adaptation ◽  
Connective Tissue Dysplasia

The proposed study was focused on search for the potential interrelations between the degree of connective tissue dysplasia (CTD) and efficiency of cardio-respiratory system adaptation to load in young athletes. Materials and methods. Parameters of cardio-respiratory system were evaluated in 200 athletes aged from 11 to 23 years with the use of cycling spiroergometry and 12-lead ECG at rest, during and after stress test. The degree of connective tissue dysplasia was assessed as per the score scale of National Guidelines. Results. It was revealed that 86% of studied athletes had moderate or marked degree of system CTD. Generally, CTD limited athletes’ cardio-respiratory system adaptation to load and was associated with myocardium repolarization disorders. Conclusion. The results of this study demonstrated that athletes with CTD showed certain changes in the electrical activity of the heart at rest and during physical exertion. Athletes with CTD compared to athletes without dysplasia have initially lower economization of the cardiovascular system and a significantly longer recovery time after exercise. This means that CTD limits the mobilization of CRS for adaptation to load, especially if the loads are cyclical.

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