scholarly journals Efficiency of elimination-irrigation therapy in children with allergic rhinitis and recurrent respiratory

2021 ◽  
pp. 93-98
Author(s):  
Tatyana G. Malanicheva ◽  
Nelli V. Ziatdinova ◽  
Guzel S. Gataullina
Keyword(s):  
Allergic Rhinitis ◽  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Comparison Group ◽  
Sea Salt ◽  
Diagnostic Methods ◽  
Respiratory Tract Diseases ◽  
Age Related ◽  
Nasal Secretions

Introduction. Despite new diagnostic methods contributing to an understanding of the etiopathogenesis of acute respiratory tract diseases and a variety of drugs for effective therapy, respiratory tract diseases continue to stand first in the overall morbidity profile in both children and adults. Frequently ill children are most susceptible to diseases, especially at the age of 3 to 6 years old, which accounts for up to 75% of all acute respiratory infection cases and shows no positive response to the medical-preventive activities. The article discusses the relationship between allergic rhinitis and recurrent respiratory diseases.Materials and methods. The possibility and effectiveness of complex treatment of allergic rhinitis in 65 frequently ill children aged 3 to 12 years are considered. The main group consisted of 35 children who were included in the traditional anti-allergic therapy with an isotonic solution of sea salt in an age-related dose for 10 days. The comparison group consisted of 30 children who received only traditional anti-allergic therapy, which was comparable in the compared groups. Patients underwent in-depth clinical and specific allergological examinations, as well as assessment of atopic response parameters of mucosal immunity, including determination of eosinophil levels, side, and Il-4 concentrations in nasal secretions.Results. Thus, the 12-month follow-up control over children with AR showed that the annual frequency of ARIs in the treatment group decreased by 1.4 times and, when averaged, was 5.2 cases, while in the comparison group it was 7.3 cases p < 0.05.Conclusions. In children with recurrent respiratory diseases, suffering from allergic rhinitis, the complex anti-allergic therapy, with the inclusion of elimination and irrigation therapy with a preparation based on isotonic sea salt solution, led to a decrease activity of markers of allergic inflammation in the nasal mucosa, which is confirmed by a decrease in the level of eosinophils, secretory IgE and IL-4 in nasal secretions against the background of a decrease in the frequency of acute respiratory diseases during follow-up for a year.

Pulmonary function in patients with chronic rhinosinusitis and allergic rhinitis

2014 ◽  
Vol 128 (3) ◽  
pp. 255-262 ◽  
Author(s):  
S Kariya ◽  
M Okano ◽  
T Oto ◽  
T Higaki ◽  
S Makihara ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Lung Function ◽  
Respiratory Tract ◽  
Pulmonary Function ◽  
Chronic Rhinosinusitis ◽  
Nasal Polyps ◽  
Immunoglobulin E ◽  
Respiratory Tract Diseases ◽  
Upper Respiratory Tract ◽  
Nasal Secretions

AbstractBackground:A close relationship between upper and lower respiratory tract diseases has been reported. However, little is known about pulmonary function in patients with upper respiratory tract diseases.Methods:Pulmonary function was measured in: 68 patients with chronic rhinosinusitis without nasal polyps, 135 patients with chronic rhinosinusitis with nasal polyps, 89 patients with allergic rhinitis and 100 normal control subjects. The relationships between pulmonary function and clinical parameters were assessed. These parameters included radiographic severity of chronic rhinosinusitis, serum total immunoglobulin E levels, concentrations of cytokines in nasal secretions and exhaled nitric oxide levels.Results:The pulmonary function of patients with chronic rhinosinusitis was significantly affected. The level of interleukin-5 in nasal secretions was significantly correlated with pulmonary function in patients with chronic rhinosinusitis.Conclusion:The findings indicated latent obstructive lung function changes in chronic rhinosinusitis patients. The cytokines in nasal secretions might be related to obstructive lung function changes in chronic rhinosinusitis.

scholarly journals New causative agents of respiratory tract diseases in immunocompromized patients (a review)

2019 ◽  
Vol 4 (3) ◽  
pp. 19-24
Author(s):  
D. D Ismatullin ◽  
M. O Zolotov ◽  
A. V Lyamin ◽  
T. R Nikitina ◽  
E. A Zheleznova ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Scientific Literature ◽  
Respiratory Tract Diseases ◽  
Respiratory Impairment ◽  
Wide Range ◽  
Causative Agents ◽  
Adults And Children ◽  
Large Families ◽  
Staphylococcus Spp

The diseases of the respiratory system occupy one of the leading positions in the range of morbidities among the Russian population, both in adults and children. Partly, it is due to an increase of patients with primary and secondary immunodeficiencies, with anatomical anomalies of the respiratory tract, and other diseases of the bronchopulmonary system. Classical pathogens, causing the bacterial respiratory diseases, as a rule, are: Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae, Pseudomonas spp., Staphylococcus spp., as well as other representatives of the Enterobacteriacae family. But each year, the scientific literature presents more and more microorganisms - pathogens of infectious diseases of various localization in humans, the clinical significance of which has long remained poorly understood. These pathogens include representatives of large families of Corynebacteriaceae, Mycobacteriaceae, Nocardiaceae. Clinical physicians need to consider possible disorders in the immune system in patients with respiratory impairment, as well as a wide range of pathogens affecting the respiratory tract. To manage such patients effectively, the close interaction of pulmonologists, bacteriologists, and allergologists-immunologists is important.

scholarly journals Upper Respiratory Tract Diseases in Athletes in Different Sports Disciplines

2016 ◽  
Vol 53 (1) ◽  
pp. 99-106 ◽  
Author(s):  
Anna Gałązka-Franta ◽  
Edyta Jura-Szołtys ◽  
Wojciech Smółka ◽  
Radosław Gawlik
Keyword(s):  
Respiratory Tract ◽  
Allergic Diseases ◽  
Medical Problem ◽  
Diagnostic Methods ◽  
Respiratory Tract Diseases ◽  
Upper Respiratory Tract ◽  
High Prevalence ◽  
Upper Respiratory ◽  
Tract Disease ◽  
Tract Infections

AbstractUpper respiratory tract diseases in athletes are a very common medical problem. Training conditions in different sports disciplines increase the risk of upper respiratory disease. Epidemiological evidence suggests that heavy acute or chronic exercise is related to an increased incidence of upper respiratory tract infections in athletes. Regular physical exercise at high intensity may lead to transient immunosuppression due to high prevalence of allergic diseases in athletes. Regardless of the cause they can exclude athletes from the training program and significantly impair their performance. In the present work, the most common upper respiratory tract diseases in athletes taking into account the disciplines in which they most often occur were presented. The focus was laid on symptoms, diagnostic methods and pharmacotherapy. Moreover, preventive procedures which can help reduce the occurrence of upper respiratory tract disease in athletes were presented. Management according to anti-doping rules, criteria for return to training and competition as an important issues of athlete’s health were discussed.

scholarly journals Development of allergic rhinitis in early life: A prospective cohort study in high-risk infants

2021 ◽  
Author(s):  
Sawako Masuda ◽  
Mizuho Nagao ◽  
Satoko Usui ◽  
Kazutaka Nogami ◽  
Yuji Tohda ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
High Risk ◽  
Development Process ◽  
Specific Ige ◽  
Nasal Symptoms ◽  
Nasal Secretions ◽  
Nasal Cytology ◽  
High Risk Infants ◽  
High Risk Cohort

Background: Allergic rhinitis (AR) is the most common allergic disease in children and is closely associated with asthma in the context of atopic march. The development process of AR in early childhood, however, is not well understood due to the absence of definitive diagnostic criteria. We prospectively investigated the process in regard to not only the nasal symptoms and sensitization, but also the nasal cytology, in relation to asthma in a high-risk cohort. Methods: Infants under 2 years of age with atopic dermatitis (AD) and/or food allergy (FA) without a diagnosis of asthma were recruited and followed prospectively for 2 years. The phenotype of perennial AR was classified based on the presence/absence of 1) persistent nasal symptoms, 2) nasal eosinophils and 3) HDM sensitization, the most common allergen for perennial AR in Japan. AR-like phenotypes were defined as positive for at least 2 of those 3 categories. Results: A total of 304 children were enrolled, and 242 subjects (80%) completed the 2-year observation. The prevalence of eosinophilia in nasal secretions increased from 18.5% to 69.9%, while HDM-specific IgE >0.35 kUA/L increased from 30.6% to 74.8%. AR-like phenotypes increased from 18.4% to 65.0%. The cumulative incidence of physician-diagnosed asthma during the 2-year follow-up was significantly higher in the subjects with an AR-like phenotype at 1 year than in those with a non-AR phenotypes. Conclusions: The prevalence of an HDM-related AR-like phenotype was markedly increased during infancy in high-risk infants with AD/FA and was associated with asthma.

scholarly journals Morfologoand anatomy-diagnostic features of the crushed combination plant medicinal product for the treatment of upper respiratory diseases

2016 ◽  
Vol 24 (4) ◽  
pp. 131-138
Author(s):  
O G Potanina ◽  
U N Buchanova
Keyword(s):  
Respiratory Tract ◽  
Medicinal Product ◽  
Respiratory Diseases ◽  
Respiratory Tract Diseases ◽  
Upper Respiratory Tract ◽  
Diagnostic Features ◽  
Product Authenticity ◽  
Upper Respiratory

The macro- and micro- diagnostic features of the combination plant medicinal product for the treatment of upper respiratory tract diseases «Lorpoliphyt» were fixed. The description, microphotos of the found features is provided. The received results are necessary further for establishment of developed combination plant medicinal product authenticity.

scholarly journals STUDY OF THE STATE OF ENT-ORGANS IN CHILDREN WITH ANOMALIES AND DEFORMATIONS OF DENTOALVEOLAR APPARATUS AND SPEECH DISORDERS

2018 ◽  
pp. 26-32
Author(s):  
P.S. Flis ◽  
N.V. Raschenko ◽  
A.O. Melnyk ◽  
V.V. Filonenko ◽  
O.I. Kotov
Keyword(s):  
Allergic Rhinitis ◽  
Magnetic Resonance ◽  
Respiratory Tract ◽  
Comparison Group ◽  
Speech Disorders ◽  
Upper Respiratory Tract ◽  
Speech Impairment ◽  
Palatine Tonsils ◽  
Comparison Groups ◽  
Upper Respiratory

The relevance of research. When examining patients with dentoalveolar anomalies, children with speech disorders can often be observed. For orthodontists, it is important to diagnose the etiologic component of these disorders, namely, whether they are the cause of diseases of the ENT-organs and whether they are directly related to orthodontic pathology. In order to study the impact of the pathology of the ENT-organs on the formation of speech disorders, clinical and additional examination methods were carried out. In case of respiratory tract narrowing due to the deviated septum, hypertrophic or allergic rhinitis, adenoid vegetations, hypertrophy of the tonsils, speech pathology may be observed. Specified pathologies are subject to treatment before the logopedic and orthodontic correction. According to our clinical study in children of the main group and of the comparison group, the apparent pathology of the nose and oropharynx was not detected. Subjective and objective methods of hearing examination also did not reveal deviations from the norm. For a more detailed study of the condition of the upper respiratory tract, it is advisable to use computer tomography of the skull and magnetic resonance therapy of the head. The purpose of research is to eliminate the influence of otorhinolaryngologic pathologies on the formation of speech disorders. Materials and methods. We examined 124 patients. Patients were divided into two groups: control and comparison. The control group consisted of 82 patients with anomalies and deformations of dentognathic apparatus and speech disorders. The comparison group consisted of 42 patients without orthodontic pathology who applied to otolaryngologists for a diagnostic examination. The examination did not show the expressed pathology of ENT-organs in the presence of speech impairment and 5 children (aged from 6 to 12 years) with ENT pathology and speech impairment were not included in the main comparison groups. To make clinical and additional diagnosis such methods as rhinoscopy, pharyngoscopy, otoscopy were used. Results and discussion. During the rhinoscopy of all the examined patients of control and comparison groups, it was found: the nasal passages were free, the nasal shells were of the usual size, the nasal membrane was in the medial position, pathological contents in the nasal cavity were not detected. During pharyngoscopy, attention was mainly paid to the size of palatine tonsils. Thus, 62 children (50%) had the 1st and 2nd stage of development, 42 (33.87%) - 2nd stage and 20 (16.13%) - II-III degree. Adenoids (nasopharyngeal tonsil) of the 1st and 2nd degree were established in 86 children (69.35%), 28 children (22.58%) - second degree and 10 (8.06%) - II-III degree, but in all children of the main and comparison groups, nasal breathing function was not noted. In 124 subjects (100%), there was no adenoid type of facial skeleton. Conclusion. With the narrowing of the respiratory tract due to a curvature of the nasal septum, hypertrophic or allergic rhinitis, adenoid vegetation, hypertrophy of the palatine tonsils, speech impairments can be observed. The specified pathologies are subject to treatment before the logopedic and orthodontic correction. According to our clinical examination of children of the main group and the groups of comparison, evident pathology of the nose and oropharynx was not detected. Subjective and objective methods of hearing examination also did not reveal deviations from the norm. For a more detailed study of the condition of the upper respiratory tract, it is advisable to use computer tomography of the skull and magnetic resonance therapy of the head.

Post Discharge Clinically Overt Venous Thromboembolism in Orthopaedic Surgery Patients with Negative Venography -an Overview Analysis

1996 ◽  
Vol 76 (06) ◽  
pp. 0887-0892 ◽  
Author(s):  
Serena Ricotta ◽  
Alfonso lorio ◽  
Pasquale Parise ◽  
Giuseppe G Nenci ◽  
Giancarlo Agnelli
Keyword(s):  
Venous Thromboembolism ◽  
Orthopaedic Surgery ◽  
Diagnostic Methods ◽  
Future Research ◽  
Post Discharge ◽  
Pharmacological Prophylaxis ◽  
Vein Thrombosis ◽  
Overview Analysis ◽  
Major Orthopaedic Surgery

SummaryA high incidence of post-discharge venous thromboembolism in orthopaedic surgery patients has been recently reported drawing further attention to the unresolved issue of the optimal duration of the pharmacological prophylaxis. We performed an overview analysis in order to evaluate the incidence of late occurring clinically overt venous thromboembolism in major orthopaedic surgery patients discharged from the hospital with a negative venography and without further pharmacological prophylaxis. We selected the studies published from January 1974 to December 1995 on the prophylaxis of venous thromboembolism after major orthopaedic surgery fulfilling the following criteria: 1) adoption of pharmacological prophylaxis, 2) performing of a bilateral venography before discharge, 3) interruption of pharmacological prophylaxis at discharge in patients with negative venography, and 4) post-discharge follow-up of the patients for at least four weeks. Out of 31 identified studies, 13 fulfilled the overview criteria. The total number of evaluated patients was 4120. An adequate venography was obtained in 3469 patients (84.1%). In the 2361 patients with negative venography (68.1%), 30 episodes of symptomatic venous thromboembolism after hospital discharge were reported with a resulting cumulative incidence of 1.27% (95% C.I. 0.82-1.72) and a weighted mean incidence of 1.52% (95% C.I. 1.05-1.95). Six cases of pulmonary embolism were reported. Our overview showed a low incidence of clinically overt venous thromboembolism at follow-up in major orthopaedic surgery patients discharged with negative venography. Extending pharmacological prophylaxis in these patients does not appear to be justified. Venous thrombi leading to hospital re-admission are likely to be present but asymptomatic at the time of discharge. Future research should be directed toward improving the accuracy of non invasive diagnostic methods in order to replace venography in the screening of asymptomatic post-operative deep vein thrombosis.

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