scholarly journals Modern possibilities of herbal medicine in the treatment of acute inflammatory diseases of the upper respiratory tract

2021 ◽  
pp. 127-133
Author(s):  
A. V. Gurov ◽  
A. V. Muzhichkova
Keyword(s):  
Phenolic Compounds ◽  
Respiratory Tract ◽  
Inflammatory Diseases ◽  
The Body ◽  
Upper Respiratory Tract ◽  
Plant Materials ◽  
Pelargonium Sidoides ◽  
Medicinal Substances ◽  
Upper Respiratory ◽  
Tract Infections

The article provides data on the effectiveness of the use of the drug in the treatment of acute, chronic and recurrent diseases of the respiratory tract and ENT organs. The drug is an extract of Pelargonium sidoides. From the standpoint of modern pharmacology, it is known that the use of natural products based on plant materials ensures safety and the absence of pronounced side effects. The main active ingredients of pelargonium are phenolic compounds: coumarins, flavonoids and phenolic acids. The article details the biochemical and pharmacological properties of each of the above groups of compounds. It has been shown that the presence of several classes of phenolic compounds simultaneously contributes to the potentiation of the pharmacological effects of each group separately. Therefore, drug has a pronounced polytropic effect: antiviral, antibacterial, immunomodulatory, mucolytic, anti-inflammatory, antioxidant, cytoprotective. The article presents the results of numerous domestic and foreign randomized, placebo-controlled studies demonstrating its high efficacy and safety in the treatment of ENT diseases, upper respiratory tract infections and bronchitis, not only in adults, but also in children over 1 year old. On the basis of the analyzed and presented material, the authors concluded that the use of a natural-based drug in the treatment of acute respiratory infection is effective and safe, both as monotherapy and in combination with other medicinal substances. He is able to quickly eliminate not only the symptoms of inflammation, but also to support the body with any ailments of this type.

scholarly journals Several studies on the problem of management patients with chronic tonsillitis during periods of remission and exacerbation

2020 ◽  
pp. 109-115
Author(s):  
A. Yu. Ovchinnikov ◽  
N. A. Miroshnichenko ◽  
Yu. O. Nikolaeva ◽  
M. M. Vasilyev
Keyword(s):  
Respiratory Tract ◽  
Randomized Clinical Trials ◽  
Inflammatory Diseases ◽  
Allergic Diseases ◽  
Lymphatic Drainage ◽  
The Body ◽  
Chronic Tonsillitis ◽  
Upper Respiratory Tract ◽  
Bacterial Strains ◽  
Upper Respiratory

Increase in the number of acute and chronic diseases is a global trend. On the one hand, the emergence of new types of viruses, their active mutation, an increase in antibiotic-resistant bacterial strains, a high frequency of immunodeficiency and allergic diseases contribute to this. On the other hand is inadequate treatment of inflammatory diseases of the upper respiratory tract, widespread use of systemic antibiotics without indications. The use of bioregulatory medicines with proven efficacy in the complex treatment can reduce the drug load on the body, reduce the bacterial complications and side effects. Traumeel®S joins the physiological course of inflammation and activates pro-resolving mediators, contributes to its faster completion and tissue repair. The efficacy and safety of Traumeel®S has been confirmed in many randomized clinical trials. The drug has proven its value in almost any inflammatory pathology of the upper respiratory tract and ear. The drug Lymphomyosot®, a multicomponent agent with lymphatic drainage action, has proven itself perfectly in the complex therapy of chronic tonsillitis. In November 2019, the Council of Experts of the National Medical Association of Otorhinolaryngologists on the problems of pathology of the lympharyngeal ring was held. It is recommended to use the multicomponent bioregulatory preparation Traumeel®S to correct the inflammatory process, which has shown in studies a modulating effect on inflammatory mediators without suppressing COX-2 (prostaglandins). With exacerbation of chronic tonsillitis and lymphadenitis of nonspecific etiology, it is possible to use the multicomponent preparation Lymphomyosot®, which helps to improve the drainage and detoxification function of the lymphatic system.

scholarly journals Species composition of certain strains of microorganisms in the development of upper respiratory tract disease in agricultural workers

2021 ◽  
Vol 100 (11) ◽  
pp. 1261-1266
Author(s):  
Lyaylya M. Masyagutova ◽  
Lilia G. Gizatullina ◽  
Maxmuza K. Gainullina ◽  
Natalya V. Vlasova ◽  
Linara A. Rafikova ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Respiratory Tract ◽  
Agricultural Production ◽  
Inflammatory Diseases ◽  
The Body ◽  
Antibacterial Drug ◽  
Upper Respiratory Tract ◽  
E Coli ◽  
Leading Role ◽  
Upper Respiratory

Introduction. Microbiocenosis is a self-regulating system of relationships between the body and microflora. Ensuring the technological process of agricultural production involves contact with conditionally pathogenic and pathogenic microflora. The spread of antibacterial drug resistance is a matter of concern. Materials and methods. There was studied the microbiocenosis of the upper respiratory tract in agricultural enterprises: in the absence of inflammatory diseases; the clinical picture of diseases of the ENT organs, and the susceptibility of the isolated strains to antibacterial drugs. Results. Working conditions of employees correspond to classes 3.1 - 3.3. Typical representatives are strains of Streptococcus, Staphylococcus, Micrococcus, Neisseria, Corynebacterium. The etiological share of S. Aureus, C. Albicans, E. Coli, Kl. Pneumoniae, Ps. Aeruginosa, predominates in the formation of inflammatory diseases. Staphylococcus are most susceptible to Cefotaxime and Sparfloxacin, followed by Cefepime, Levofloxacin and Amikacin. Strains of Kl. pneumoniae are susceptible to Cefotaxime and Sparfloxacin; strains of Pseudomonas aeruginosa - to Cefepime and Ceftazidim; C. Albicans and C. crusei - to Amphotericin B and Fluconazole. Conclusion. The complex industrial factors of agricultural production contributes to the violation of the ratio of microbial associations even against the background of clinical health, which is a risk factor for the development of inflammatory processes. S. Aureus strains; Candida Albicans; Klebsiella Pneumoniae play the leading role. Pseudomonas aeruginosa and E. Coli. The isolates demonstrate multidrug resistance to antimicrobial drugs.

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