Pulp Tissue Response to Platelets Rich Plasma, Platelets Rich Fibrin and Mineral Trioxide Aggregate as Pulp Capping Materials

2021 ◽  
Vol 8 (4) ◽  
pp. 561-570
Author(s):  
Sarah D. Shaheen ◽  
Maha A. Niazy ◽  
Wael E. Jamil ◽  
Ashraf M. Abu-Seida
Keyword(s):  
Mineral Trioxide Aggregate ◽  
Tissue Response ◽  
Pulp Tissue ◽  
Pulp Capping

scholarly journals MTA and calcium hydroxide for pulp capping

2005 ◽  
Vol 13 (2) ◽  
pp. 126-130 ◽  
Author(s):  
Alexandra Mussolino de Queiroz ◽  
Sada Assed ◽  
Mario Roberto Leonardo ◽  
Paulo Nelson-Filho ◽  
Léa Assed Bezerra da Silva
Keyword(s):  
Calcium Hydroxide ◽  
Mineral Trioxide Aggregate ◽  
Inflammatory Cells ◽  
Direct Pulp Capping ◽  
Water Control ◽  
Pulp Tissue ◽  
Pulp Capping ◽  
Tissue Changes ◽  
Maxilla And Mandible ◽  
Direct Capping

This study evaluated the biocompatibility of mineral trioxide aggregate (MTA) after direct capping of exposed pulp tissue in dog's teeth. Class I cavities were prepared in 26 teeth from 3 adult dogs. MTA was applied over the exposed pulp in 13 teeth and paste of calcium hydroxide plus distilled water (control) was applied in the remaining 13 teeth. After 90 days, the animals were killed; the maxilla and mandible were dissected and sectioned to obtain individual roots. The samples were processed histologically. The pulp and periapical response observed with the use of MTA was similar to that of calcium hydroxide paste. In all specimens, there was a dentin bridge obliterating the exposure, an intact odontoblastic layer, no inflammatory cells, normal connective pulp tissue, normal apical and periapical regions and no bone tissue changes. Similar to calcium hydroxide, MTA presented excellent response when used for direct pulp capping.

scholarly journals Influence of Pregnancy on the Inflammatory Process Following Direct Pulp Capping: a Preliminary Study in Rats

2019 ◽  
Vol 30 (1) ◽  
pp. 22-30
Author(s):  
Luiza Helena Silva Almeida ◽  
Katerine Jahnecke Pilownic ◽  
Sandra Beatriz Chaves Tarquínio ◽  
Anelize Campello Felix ◽  
Fernanda Geraldo Pappen ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Inflammatory Process ◽  
Inflammatory Infiltrate ◽  
Resin Composite ◽  
Mineral Trioxide Aggregate ◽  
Optical Microscope ◽  
Tissue Response ◽  
Direct Pulp Capping ◽  
Pulp Capping ◽  
Tissue Organization

Abstract The purpose of this study was to evaluate the inflammatory process following direct pulp capping during pregnancy. This experimental study involved 48 maxillary first molars of female Wistar rats. The procedures were performed in pregnant and non-pregnant animals (n =20 each). Direct pulp capping with mineral trioxide aggregate (MTA) and restoration with a light-cured resin composite was performed in half of exposed pulp specimens. In the other half of specimens, light-cured composite was placed directly on the exposed pulp. In the control groups (n=4 each), no intervention was performed. Animals were euthanized at 3 and 7 days. All sections (three per slide) were viewed under an optical microscope. One previously calibrated pathologist performed descriptive analysis and assigned scores for inflammatory response and tissue organization adjacent to the pulp exposure. The Kappa value for intra-examiner variability was 0.91. At 3 days, in animals treated with MTA, inflammatory infiltrate was absent in non-pregnant animals while mild inflammatory infiltrate was observed in some pregnant animals. The inflammatory response ranged from mild to severe in both groups treated with composite alone. At 7 days, the inflammatory response was more intense in pregnant than in non-pregnant animals treated with MTA; while this difference were not evident in animals treated with composite alone. In conclusion, pregnancy may not influence the inflammatory process following direct pulp capping with light-cured resin composite, which was always harmful to the pulp; while the tissue response after the direct pulp with MTA were more favorable in non-pregnant animals.

scholarly journals Evaluation of human pulp tissue response following direct pulp capping with a self-etching adhesive system containing MDPB

2021 ◽  
Author(s):  
Nevin COBANOGLU ◽  
Tuncay ALPTEKİN ◽  
Haruaki KITAGAWA ◽  
Markus B BLATZ ◽  
Satoshi IMAZATO ◽  
...  
Keyword(s):  
Adhesive System ◽  
Tissue Response ◽  
Direct Pulp Capping ◽  
Pulp Tissue ◽  
Pulp Capping

scholarly journals The thickness of odontoblast-like cell layer after induced by propolis extract and calcium hydroxide

2016 ◽  
Vol 49 (1) ◽  
pp. 17
Author(s):  
Irfan Dwiandhono ◽  
Ruslan Effendy ◽  
Sri Kunarti
Keyword(s):  
Calcium Hydroxide ◽  
Cell Layer ◽  
Tissue Response ◽  
Histological Evaluation ◽  
Bacterial Invasion ◽  
Direct Pulp Capping ◽  
Pulp Tissue ◽  
Propolis Extract ◽  
Pulp Capping ◽  
Pulp Inflammation

Background: Propolis is a substance made from resin collected by bees (Apis mellifera) from variety of plants, mixed with its saliva and various enzymes to build a nest. Propolis has potential antimicrobial and antiinflammatory agents with some advantages over calcium hydroxide (Ca(OH)2). Ca(OH)2 has been considered as the “gold standard” of direct pulp-capping materials, but there are still some weakness of its application. First, it can induce pulp inflammation which last up to 3 months. Second, the tissue response to Ca(OH)2 is not always predictable. Third, the tunnel defect can probably formed in dentinal bridge with possible bacterial invasion in that gap. Purpose: This study was aimed to determine and compare the thickness of odontoblast-like cells layer after induced by propolis extract and Ca(OH)2 in rat’s pulp tissue. Method: Class 1 preparation was done in maxillary first molar tooth of wistar mice until the pulp opened. The Ca(OH)2 and propolis extract was applied to induce the formation of odontoblast-like cells, the cavity was filled with RMGIC. The teeth were extracted (after 14 and 28 days of induction). The samples were then processed for histological evaluation. Result: There were significant differences between the thickness of odontoblast-like cells after induced by propolis extract and Ca(OH)2. Conclusion: The propolis extract as the direct pulp capping agent produces thicker odontoblast-like cell layer compared to Ca(OH)2.

scholarly journals THE INFLAMMATORY REACTION OF PULP TISSUE WITH CALCIUM HYDROXIDE, MTA AND PORTLAND CEMENT (In Vivo)

2017 ◽  
Vol 4 (2) ◽  
pp. 114
Author(s):  
Jos Erry Hesti Witasari ◽  
Usman Munyati ◽  
Anggraini Dewi
Keyword(s):  
Portland Cement ◽  
Calcium Hydroxide ◽  
Inflammatory Reaction ◽  
Mineral Trioxide Aggregate ◽  
Direct Pulp Capping ◽  
Pulp Tissue ◽  
Posterior Teeth ◽  
Capping Agents ◽  
Pulp Capping

Background : Perforation in normal pulp could be happened anytime. In sterile condition, direct pulp capping was the right therapy to maintain the vitality and pulp function. Direct pulp capping agent must contact with the pulp tissue. Generally, body had an immunologic respond with foreign body that contact with tissue. The respond could be inflammatory reaction. The used direct pulp capping agents were calcium hydroxide, and Mineral Trioxide Aggregate (MTA) which known as better agent but relatively expensive and difficult to obtain. So that, the alternative of MTA, Portland cement which was the same essential of MTA, was being developed. The aim of this study, to analized inflammatory reaction of the pulp tissue with direct pulpcapping agents calcium hydroxide, MTA, and Portland cement.Methods: Free caries M. Nemestrina’s posterior teeth were prepared to formpin point perforations on buccal surface of the crowns. The teeth were appliedwith one of the three capping agents. Teeth were filled and extracted. Theextracted teeth were proceed into histopatological preparation slides to evaluatethe inflammatic reaction.Results: The result showed no statistically significant differences of pulp inflammatory reaction between calcium hydroxide, MTA and Portland cement in7, 14, 42, and 90 days.Conclusion: The inflammatory reaction of pulp tissue of the three pulp cappingagent (calcium hydroxide, MTA, and PC) were insignificant different.

Synthesis and Characterization of a Novel SCPC-CO3Ap Cement for Pulp Capping Application in Dentistry

2017 ◽  
Vol 758 ◽  
pp. 29-33 ◽  
Author(s):  
Arief Cahyanto ◽  
Andri Rezano ◽  
Myrna Nurlatifah Zakaria ◽  
Ahmed El-Ghannam
Keyword(s):  
Mechanical Strength ◽  
Antibacterial Properties ◽  
Tissue Response ◽  
Carbonate Apatite ◽  
Pulp Tissue ◽  
Dental Tissue ◽  
Compact Structure ◽  
Pulp Capping ◽  
Ft Ir ◽  
Dentin Regeneration

Silica-calcium phosphate composite (SCPC) and carbonate apatite (CO3Ap) have several superior properties as they are bioactive, bioresorbable and elicit excellent tissue response. The CO3Ap surface layer and hydrated silica developed on the surface of the SCPC may be a key factor for achieving dentin regeneration. On the other hand, calcium hydroxide [Ca(OH)2] have antibacterial properties and biocompatible to dental tissue. Therefore, the combination of CO3Ap, SCPC, and Ca(OH)2 in a bone cement may be favorable as a pulp capping agent that enhances pulp tissue formation and dentin regeneration. The aim of the present study is to synthesize and characterize a novel SCPC-CO3Ap cement for pulp capping application in dentistry. The cement is composed of dicalcium phosphate anhydrous (DCPA), vaterite, Ca(OH)2 and SCPC. The set cement was further characterized by Fourier transform infrared (FT-IR). The microstructure of set cement was examined by scanning electron microscopy (SEM) and the mechanical strength was evaluated by diametral tensile strength (DTS). The FT-IR analyses revealed that the additional bands of carbonate were detected in each sample. The SEM samples of set cement showing more compact surface microstructure of group II compared to other groups. Furthermore, the combination of 5% SCPC and 5% Ca(OH)2 in the cement facilitated a compact structure with superior mechanical strength. The novel SCPC-CO3Ap cement has great potential to be used for pulp capping to facilitate dentin regeneration.

scholarly journals Biosealer versus Biodentine for direct pulp capping in dog’s teeth: A histopathological evaluation

2019 ◽  
Author(s):  
Inas M. Al-Sherbiny ◽  
Mona H. Farid ◽  
Ashraf M. Abu-Seida ◽  
Inas Motawea ◽  
Hagar A. Bastawy
Keyword(s):  
Blood Vessels ◽  
Tissue Response ◽  
Control Group ◽  
Image Analyzer ◽  
Pulp Tissue ◽  
Bridge Formation ◽  
Pulp Capping ◽  
Exposure Site ◽  
Reparative Dentin ◽  
Pulp Exposure

Abstract BackgroundThis study compared the effect of Biodentine (BD) and Tech Biosealer Capping (BS) on the pulpal tissue response after pulp capping in dogs, teeth.MethodsThree mongrel dogs were enrolled in this study. Class V cavities with pulp exposure were performed on the buccal surface of 30 teeth (2 experimental groups) and left without pulp exposure in 15 teeth (control group). The cavities of experimental groups were capped with either Biodentine (BD Group, N= 15 teeth) or Tech-Biosealer Capping (BS Group, N= 15 teeth). All cavities (experimental and control groups) were restored with resin-modified glass ionomer. Dentine bridge formation, architechecture of the odontoblastic layers and signs of inflammation were assessed after 1, 2 and 3 months using the computer image analyzer (Leica Qwin 500).ResultsBD group showed a thick newly formed reparative dentin bridge completely closing the exposure site with cell inclusions and mineralization, variable amount of odontoblast-like cells, preserved pulp tissue, marked numerous collagen fibers and blood vessels. While BS group showed an incomplete newly formed reparative dentin bridge with tunnel defect, vacuolated odontoblasts, complete pulp degeneration with multiple edematous spaces, hyperemic blood vessels, extravasated RBCs, multiple calcified structures scattered just beneath the dentin bridge and through the pulp tissue, and newly ill-defined odontoblasts.ConclusionFor pulp capping, Biodentine has better dentine bridge formation and pulp preservation than Tech Biosealer Capping.

Physical properties of different Pulp Capping Materials and Histological Analysis of their effect on Dogs’Dental Pulp Tissue Healing

2018 ◽  
Vol 64 (3) ◽  
pp. 2657-2667
Author(s):  
Mai Hamdy ◽  
Dalia Fayyad ◽  
Mohamed Eldaharawy ◽  
Enas Hegazy
Keyword(s):  
Physical Properties ◽  
Histological Analysis ◽  
Pulp Tissue ◽  
Pulp Capping ◽  
Tissue Healing

scholarly journals Clinical and Histological Evaluation of Direct Pulp Capping on Human Pulp Tissue Using a Dentin Adhesive System

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Alicja Nowicka ◽  
Ryta Łagocka ◽  
Mariusz Lipski ◽  
Mirosław Parafiniuk ◽  
Katarzyna Grocholewicz ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Third Molar ◽  
Adhesive System ◽  
Histological Evaluation ◽  
Control Group ◽  
Single Bond ◽  
Pulp Tissue ◽  
Pulp Capping ◽  
Hydroxide Group ◽  
Dentin Adhesive

Objective. This study presents a clinical and histological evaluation of human pulp tissue responses after direct capping using a new dentin adhesive system. Methods. Twenty-eight caries-free third molar teeth scheduled for extraction were evaluated. The pulps of 22 teeth were mechanically exposed and randomly assigned to 1 of 2 groups: Single Bond Universal or calcium hydroxide. Another group of 6 teeth acted as the intact control group. The periapical response was assayed, and a clinical examination was performed. The teeth were extracted after 6 weeks, and a histological analysis was performed. The pulp status was assessed, and the thickness of the dentin bridge was measured and categorized using a histological scoring system. Results. The clinical phase was asymptomatic for Single Bond Universal patients. Patients in the calcium hydroxide group reported mild symptoms of pain, although the histological examination revealed that dentin bridges with or without limited pulpitis had begun forming in each tooth. The universal adhesive system exhibited nonsignificantly increased histological signs of pulpitis (P>0.05) and a significantly weaker thin mineralized tissue layer (P<0.001) compared with the calcium hydroxide group. Conclusion. The results suggest that Single Bond Universal is inappropriate for human pulp capping; however, further long-term studies are needed to determine the biocompatibility of this agent.

scholarly journals Temperature changes in the pulp chamber induced by polymerization of resin-based dental restoratives following simulated direct pulp capping

2019 ◽  
Vol 73 (4) ◽  
pp. 239-248
Author(s):  
Violeta Petrovic ◽  
Jovana Stasic ◽  
Vojislav Komlenic ◽  
Tatjana Savic-Stankovic ◽  
Marina Latkovic ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Mineral Trioxide Aggregate ◽  
Glass Ionomer ◽  
Direct Pulp Capping ◽  
Pulp Chamber ◽  
Temperature Changes ◽  
Pulp Capping ◽  
Dental Restoratives ◽  
Resin Modified Glass Ionomer ◽  
Light Curing

The objective of this study was to measure temperature changes in the pulp chamber induced by polymerization of resin-based dental restoratives following a simulated procedure of direct pulp capping. Class I cavities with a microperforation at the pulp horn were prepared in extracted human molar teeth. The complete procedure of direct pulp capping and cavity restoration was performed with the root part of extracted teeth fixed in a water bath at 37 ?C. Mineral trioxide aggregate, bioactive dentin substitute or calcium-hydroxide paste were used as pulp capping materials. Cavities were restored with a light-cured or chemically-cured resin-modified glass ionomer, universal adhesive and a bulk-fill composite, cured with a high-intensity LED unit. Pulp capping materials caused a slight temperature decrease. Lower temperature increase was recorded during light-curing of the glass ionomer liner after direct capping with mineral trioxide aggregate and calcium-hydroxide than that recorded for the bioactive dentin substitute. Adhesive light-curing increased temperature in all groups with higher mean temperatures in groups with chemically-cured as compared to those for the light-cured glass ionomer liner. Direct pulp capping with mineral trioxide aggregate or calcium-hydroxide followed by the light-cured resin-modified glass ionomer liner and a bonded bulk-fill composite restoration induced temperature changes below the potentially adverse threshold of 42.5?C.

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