scholarly journals Phytochemical study, antioxidant and cytotoxic activities of Brassica rapa L. leaves extract and its silver nanoparticles

2018 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Reham shafek ◽  
helana michael ◽  
ahmed sayed ◽  
ahmed ibrahim ◽  
Ahmed Al-sayed
Keyword(s):  
Silver Nanoparticles ◽  
Brassica Rapa ◽  
Cytotoxic Activities ◽  
Phytochemical Study

scholarly journals Green ultrasonic synthesis, Characterization and Antibacterial activity of Silver and Gold Nanoparticles mediated by Ganoderma lucidum extract

2020 ◽  
Vol 4 (2) ◽  
Keyword(s):  
Gold Nanoparticles ◽  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Metal Nanoparticles ◽  
Cytotoxic Activities ◽  
Gold And Silver Nanoparticles ◽  
Silver And Gold Nanoparticles ◽  
E Coli ◽  
Inhibition Zones

Metal nanoparticles possess an extensive scientific and technological significance due to their unique physiochemical properties and their potential applications in different fields like medicine. Silver and gold nanoparticles have shown to have antibacterial and cytotoxic activities. Conventional methods used in the synthesis of the metal nanoparticles involve use of toxic chemicals making them unsuitable for use in medical field. In our continued effort to explore for simple and eco-friendly methods to synthesize the metal nanoparticles, we here describe synthesis and characterization of gold and silver nanoparticles using Gonaderma lucidum, wild non-edible medicinal mushroom. G. lucidum mushroom contain bioactive compounds which can be involved in the reduction, capping and stabilization of the nanoparticles. Antibacterial activity analysis was done on E. coli and S. aureus. The synthesis was done on ultrasonic bath. Characterization of the metal nanoparticles was done by UV-VIS., High Resolution Transmission Electron Microscope (HRTEM) and FTIR. HRTEM analysis showed that both silver and gold nanoparticles were spherical in shape with an average size of 15.82±3.69 nm for silver and 24.73±5.124nm for gold nanoparticles (AuNPs). FTIR analysis showed OH and -C=C- stretching vibrations, an indication of presence of functional groups of biomolecules capping both gold and silver nanoparticles. AgNPs showed inhibition zones of 15.5±0.09mm and 13.3±0.14mm while AuNPs had inhibition zones of 14.510±0.35 and 13.3±0.50mm on E. coli and S. aureus respectively. The findings indicate the potential use of AgNPs and AuNPs in development of drugs in management of pathogenic bacteria.

scholarly journals Fruit waste (peel) as bio-reductant to synthesize silver nanoparticles with antimicrobial, antioxidant and cytotoxic activities

2018 ◽  
Vol 16 (3) ◽  
pp. 221-231 ◽  
Author(s):  
Annu Annu ◽  
Shakeel Ahmed ◽  
Gurpreet Kaur ◽  
Praveen Sharma ◽  
Sandeep Singh ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Cytotoxic Activities ◽  
Synthesize Silver Nanoparticles ◽  
Fruit Waste

scholarly journals Two New Cyclobutane Dimers from Diospyros macrocarpa

2017 ◽  
Vol 12 (8) ◽  
pp. 1934578X1701200
Author(s):  
Charlotte Thieury ◽  
Rémy Le Guével ◽  
Gaëtan Herbette ◽  
Valérie Monnier ◽  
Nicolas Lebouvier ◽  
...  
Keyword(s):  
Cancer Cell ◽  
New Caledonia ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Cancer Cell Line ◽  
Cytotoxic Activities ◽  
Endemic Plant ◽  
Leaf Extracts ◽  
Phytochemical Study ◽  
Cyclobutane Dimers

A biochemical and phytochemical study of Diospyros macrocarpa Hiern, an endemic plant of New Caledonia, was realized. Indeed, bark and leaf extracts were tested for their cytotoxic and antibiotic activities as well as for their radical scavenging properties. Methanol extracts showed promising radical scavenging activity with an IC50 value of 5.6 ± 0.9 μg/mL for the leaves and 8.1 ± 1.4 μg/mL for the barks. The ethyl acetate extract from the barks showed strong and selective activity against NCI-H727 cancer cell line with an IC50 value of 9.5 ± 0.6 μg/mL.. Two new cyclobutane dimers: macrocarpasin A (1) and B (2) (figure 1) together with six known compounds: yangonin (3), betulinic acid (4), α-amyrin (5), β–amyrin (6), loliolide (7) and oleanderolide (8) were isolated from leaf extracts. Their structures were established by 1D and 2D NMR along with HRMS analyses. Cytotoxic activities of isolated compounds were also evaluated. None of them showed interesting cytotoxicity against the seven tested cancer cell lines.

Preparation of silver nanoparticles using aqueous extracts of the red algae Laurencia aldingensis and Laurenciella sp. and their cytotoxic activities

2015 ◽  
Vol 28 (4) ◽  
pp. 2615-2622 ◽  
Author(s):  
Adriana Pires Vieira ◽  
Erika Mattos Stein ◽  
Daniel Xavier Andreguetti ◽  
Pio Colepicolo ◽  
Ana Maria da Costa Ferreira
Keyword(s):  
Silver Nanoparticles ◽  
Red Algae ◽  
Cytotoxic Activities ◽  
Aqueous Extracts

Encapsulation of Silver Nanoparticles in Polylactic Acid or Poly(lactic-co-glycolic acid) and Their Antimicrobial and Cytotoxic Activities

2019 ◽  
Vol 19 (11) ◽  
pp. 6933-6941
Author(s):  
Daissy Julieth Paredes Guerrero ◽  
Jhon Jhamilton Artunduaga Bonilla ◽  
Claudia Cristina Ortiz López ◽  
Rodrigo Gonzalo Torres Sáez
Keyword(s):  
Silver Nanoparticles ◽  
Mammalian Cells ◽  
Metallic Nanoparticles ◽  
Pathogenic Bacteria ◽  
Polymeric Nanoparticles ◽  
Candida Guilliermondii ◽  
Cytotoxic Activities ◽  
Polymeric Nanocomposites ◽  
Murine Fibroblast ◽  
Average Size

Encapsulation with biodegradable polymers is an alternative to reduce adverse effects and improve the physicochemical properties of metallic nanoparticles. In this study, spherical polymeric nanoparticles with an average size of 200 nm loaded with silver nanoparticles (AgNPs) were obtained. The antimicrobial activity against Escherichia coli O157:H7, methicillin-resistant Staphylococcus aureus (MRSA), and yeasts as Candida albicans, Candida parapsilosis and Candida guilliermondii was determined. MIC90 values of nanocomposites were between 0.01 to 1 μg/mL, potentialized effect up to 500 times compared to free AgNPs. In addition, cytotoxic effect on 50% of murine fibroblast (CC50) was obtained at a mean concentration of 9.57 μg/mL of AgNPs (up to ~1000 times higher than MIC90). Consequently, the polymeric nanocomposites loaded with AgNPs are a potential alternative in the development of new biocide agents on Candida species and pathogenic bacteria at non-toxic concentrations for mammalian cells such as murine fibroblasts.

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