Antioxidant and Anti-ulcer Activities of Fermented soybean (Natto) and Moringa oleifera leaves in Male Albino Rats

Cereal gruel is the common complementary foods in developing countries, and it is usually low in energy and protein; hence, responsible for increase in protein-energy malnutrition among underprivileged weaning aged children. Several locally available food materials have been tested in combination for infant food formulations however; popcorn and Moringa oleifera leaves combination have not been used. After blanching and fermentation processing, popcorn and moringa leaves were milled into flour and blended to obtain, blanched popcorn-moringa leaves (BPM) (65% popcorn and 35% moringa leaves flour) and fermented popcorn-moringa leaves (FPM) (65% popcorn and 35% moringa leaves flour). Products were analyzed for chemical composition, functional properties and bioassay using standard methods. Protein content of FPM (21.27 ± 0.20 g/100 g) and BPM (15.99 ± 0.14 g/100 g) were higher than Cerelac (15.75 ± 0.01 g/100 g) and ‘Ogi’ (6.52 ± 0.31 g/100 g); while energy values of FPM (393.94 ± 0.39 kcal) and BPM (389.69 ± 1.40 Kcal) were lower than ‘Ogi’ (418.08 ± 0.47 kcal) and Cerelac (431.58 ± 0.01 kcal). Mineral contents of BPM were higher in zinc, iron, potassium, sodium and phosphorous, while FPM sample was higher in copper, calcium and magnesium, and were lower than Cerelac. Oxalate, phytate and trypsin inhibitor in FPM were lower than BPM. Biological value and protein efficiency ratio of FPM were higher than BPM and ‘Ogi’, but lower than Cerelac. The albino rats fed with the FPM had higher growth rate when compared with those rats fed with BPM sample and ‘Ogi’, but lower than those fed with Cerelac. Nutrient composition and nutritional profile of popcorn-moringa leaves based complementary foods could be used as substitutes for local complementary foods, which are low in protein and energy.

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Effects of Moringa oleifera lam. Leaf Powder on Bifidobacteria and Escherichia coli in the Gut of Albino Rats

Journal of Advances in Microbiology ◽

10.9734/jamb/2019/v18i230168 ◽

2019 ◽

pp. 1-11

Author(s):

A. O. Gbadebo ◽

O. T. Okareh ◽

A. A. Ogunjobi ◽

A. O. Dada

Keyword(s):

Escherichia Coli ◽

Body Weight ◽

Moringa Oleifera ◽

Albino Rats ◽

Control Groups ◽

Moringa Oleifera Leaves ◽

Leaf Powder ◽

Group A ◽

Group B ◽

Animal House

Aim: This study was carried out to determine the effects of dried Moringa oleifera leaves on Bifidobacteria and Escherichia coli in the gut of albino rats. Location: The rats were habituated under laboratory conditions at the animal house of the Department of Zoology, Faculty of Science, University of Ibadan, for two weeks in other to adapt to the environmental conditions during the experiment. Duration of Study: The rats were exposed to the M. oleifera feed for four weeks. Design of Study: There were five groups in all. The 5 to 6 weeks old rats were fed with M. oleifera powder supplement except for the control groups. Methods: No supplement of M. oleifera feed was administered to group A while group B received streptomycin antibiotics. Groups C, D and E received dried leaf supplement of M. oleifera (DMO) 1.25 g/kg body weight (2.5%), 2.5 g/kg body weight (5%) and 5.0 g/kg body weight (10%) respectively. Results: E.coli counts increased from 2.3*104 to 2.6*104 colony-forming units per gram (cfu/g) in group E, from 2.2*104 to 3.0*10 cfu/g in group B; but reduced from 4.1*104 to 3.7*104 cfu/g in group D and from 5.4*104 to 3.9*104 cfu/g in group C between day 20 and day 28. As from day 8, the isolates from the non-control groups were resistant to the M. oleifera extract except E. coli isolates in both 5% and 10% M. oleifera groups on day 8 with 6 mm zone of inhibition each. The rate of Bifidobacteria viable counts increase in group E was expressed as P = 0.05 at the beginning of the experiment, unlike E.coli counts where there was a decrease. Conclusion: The M. oleifera leaf alters the microbiota in the gut, a situation which sends impulses to the brain. Thus, the M. oleifera leaf powder is a potential prebiotic for probiotics like Bifidobacteria, and as well as induce changes in the gut-brain axis.

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Antipyretic effect of ethanolic extract of Moringa oleifera leaves on albino rats

Tanta Medical Journal ◽

10.4103/1110-1415.137810 ◽

2014 ◽

Vol 42 (2) ◽

pp. 74

Author(s):

Ayon Bhattacharya ◽

Sanjay Kumar ◽

SudhanshuS Mishra ◽

PratapK Sahu ◽

Divya Agrawal ◽

...

Keyword(s):

Moringa Oleifera ◽

Ethanolic Extract ◽

Albino Rats ◽

Antipyretic Effect ◽

Moringa Oleifera Leaves

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Effects of Moringa oleifera Leaves Methanolic Extract on Alloxan- Induced Diabetic Albino Rats

Asian Journal of Research in Medical and Pharmaceutical Sciences ◽

10.9734/ajrimps/2019/v7i230119 ◽

2019 ◽

pp. 1-8

Author(s):

C. Udeogu ◽

C. C. Ejiofor ◽

A. Nwakulite

Keyword(s):

Blood Glucose ◽

Blood Glucose Level ◽

Glucose Level ◽

Moringa Oleifera ◽

Albino Rats ◽

High Blood Glucose ◽

Before And After ◽

Moringa Oleifera Leaves ◽

Group 2 ◽

Wistar Albino Rats

Moringa oleifera, popularly known as “miracle tree” belongs to the family, Moringaceae. It is a medicinal plant in which the leaves are the most nutritious part, being a significant source of vitamins and protein among others. This study was conceived and designed based on the gaps in the research that has been performed and what is known about the plant. In this study, the effect of Moringa oleifera leaves extract on alloxan induced diabetes in Wistar albino rats was investigated. A total of forty five (45) rats were acclimatized for a period of two weeks, then randomly divided into five (5) groups (1, 2, 3, 4, and 5) of nine (9) rats each and fed with standard feed and water. Group 1 which is the control was fed with just water and standard feed while Hyperglycemia was induced in groups 2, 3, 4, & 5 intra-peritoneally after an over-night fasting using alloxan at a concentration of 130 mg/kg b.w. and allowed for 48hours which resulted in a high blood glucose level between 300 mg/dl and 600 mg/dl. Group 2 was not given any treatment while Groups 3, 4, & 5 were treated with doses 100 mg/kg b.w., 200 mg/kg bw, and 400 mg/kgbw of Moringa oleifera leaf extract respectively for a period of four weeks. A glucometer was used to check the blood glucose level of the animals before and after treatment. The results of Groups 3, 4, & 5 (172.0±4.75 mg/dl, 142.9±47.25 mg/dl, 70.6±24.46 mg/dl respectively) showed a significant decrease (p< 0.05) in blood glucose level of the induced rats when compared with Group 2 (316±47.17 mg/dl) which was induced only alloxan. It can therefore be concluded that this study has shown that the extract of Moringa oleifera leaves offers an anti-diabetic effect in Wistar albino rats.

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