scholarly journals Serum Vitamin D Level in Type 2 Diabetic Subjects: Relation to Glycemic Control, Insulin Resistance and Proinflammatory Markers

2017 ◽  
Vol 47 (2) ◽  
pp. 62-68
Author(s):  
Talaat Abdel Aaty ◽  
Magdy Magallaa ◽  
Hend Abdel Moneim ◽  
Hanaa Ismail ◽  
Doaa Genena ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Glycemic Control ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Type 2 Diabetic

scholarly journals Assessment of vitamin D status and its association with insulin resistance among type 2 diabetic subjects

2018 ◽  
Vol 6 (12) ◽  
pp. 3825
Author(s):  
Jaitra Bhattacharya
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Type 2 Diabetic

Background: The 21st century has seen the rise of diabetes mellitus as one of the major metabolic issues as is vitamin D deficiency which has been found to be pandemic worldwide. The present study is an endeavor to study the status of serum vitamin D levels in relation to the glycemic and insulin resistance status in type 2 diabetes mellitus patients.Methods: The present is a cross-sectional study with a sample size of 100 type 2 diabetic subjects in the age group of 30-60 years. Serum vitamin D and Insulin levels were estimated using the ELISA technique. HbA1c levels were measured using immunoturbidimetric assays and plasma glucose levels were determined using glucose oxidase- peroxidase method.Results: The fasting plasma glucose, HbA1c and serum insulin levels were found to be significantly higher in those with vitamin D levels below the normal cut-off value of less than 30ng/ml (p value <0.01). Also, the insulin resistance calculated using HOMA-IR was found to be higher in those subjects having vitamin D deficiency or insufficiency.Conclusions: Hence, the study suggests that vitamin D deficiency contributes to further insulin resistance and poorer long-term diabetic control in type 2 diabetes mellitus subjects.

STUDY OF SERUM VITAMIN-D IN TYPE-2 DIABETES MELLITUS PATIENTS.

2021 ◽  
pp. 187-188
Author(s):  
Ajay Jain ◽  
Debina sarkar ◽  
G.G. Kaushik ◽  
Ankita Sharma
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Healthy Subjects ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
Type 2 Diabetic

Background: Type-2 diabetes mellitus (T2DM) is a progressive and chronic disease characterized by both β-cell dysfunction and increased insulin resistance. Diabetes mellitus is now considered a giant killer disease of the 21st century with its vicious prongs in the South-East Asian countries, specially India, which is rightly said to be the ''Diabetes Capital'' of the world. Vitamin D has important effects on insulin action, and may impact on a number of pathways which may be of importance in the development of type 2 diabetes mellitus. Materials & Methods: In this study 62 Type-2 diabetic patients, 62 healthy controls were enrolled. Biochemical analytes measured were Serum glucose (Fasting Blood Sugar & Post Prandial Blood Sugar), Glycosylated Haemoglobin, Serum Vitamin-D. Results: The mean Serum Vitamin-D in Type-2 diabetic subjects were (16.3 ±3.0) while in healthy subjects(controls) the values were (39.3±5.2) respectively. These values were found to be statistically highly signicant(p<0.001). Conclusion: Serum Vitamin-D levels were decreased in Type 2 diabetic subjects as compared to the values in healthy subjects(controls).

scholarly journals Glycated Haemoglobin Is Inversely Related to Serum Vitamin D Levels in Type 2 Diabetic Patients

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e82733 ◽  
Author(s):  
Giacomo Zoppini ◽  
Anna Galletti ◽  
Giovanni Targher ◽  
Corinna Brangani ◽  
Isabella Pichiri ◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Vitamin ◽  
Glycated Haemoglobin ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Type 2 Diabetic

scholarly journals SERUM VITAMIN D LEVEL IN TYPE 2 DIABETIC PATIENTS

2018 ◽  
Vol 21 (05) ◽  
pp. 992-997
Author(s):  
Imran Ali Shaikh ◽  
Naila Masood ◽  
Shazia Memon
Keyword(s):  
Vitamin D ◽  
Serum Vitamin ◽  
Control Group ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Type 2 Diabetic

Objective: To find out serum vitamin D levels in type 2 DM patients in Hyderabad.Design: Cross sectional study. Setting: Private clinics, OPDs of government hospitals likeQasimabad, Latifabad and Pretabad. Duration: January to July 2013. Patients and Methods:Total 550 patients were selected, 450 patients (250 males and 200 females) taken from differentOPDs of Hyderabad and towns or Tehsils with diagnosis of type 2 Diabetes mellitus andanother 100 patients were taken as control (60 males and 40 females). The mean age was45.6 years. The written consent was obtained and demographic features were noted, 3cc ofblood was taken for estimation of vitamin D levels. The level of vitamin D was done on anElectrochemiluminescence Immuno Assay (ECLIA) at Diagnostic & Research laboratory LiaquatUniversity of Medical &Health sciences (LUMHS) Jamshoro, Sind. Results and Observations:Out of 550, 450 diabetic subjects tested for vitamin D, females were 44.4%and 55.5% weremales. The deficiency was seen in 33.7% patients (p <0.04) and Vitamin D insufficiency wasobserved in20% in both sex. In control group, the deficiency was observed in 23% in femalesand 20% in males while insufficiency noted in 5% in both sex. Conclusions: The study showedsignificant decreased levels of vitamin D in type 2 Diabetic subjects than normal individuals. Thevitamin D deficiency increased considerably in females with diabetes type 2.

scholarly journals Association between serum vitamin D and insulin resistance in African Americans with type 2 diabetes (1030.3)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Joel Exebio ◽  
Gustavo Zarini ◽  
Joan Vaccaro ◽  
Sahar Ajabshir ◽  
Amanpreet Cheema ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
African Americans ◽  
Serum Vitamin ◽  
Serum Vitamin D

scholarly journals Prevalence and severity of vitamin D deficiency in type 2 diabetic patients

2020 ◽  
Vol 7 (8) ◽  
pp. 1251
Author(s):  
Dipesh Patel ◽  
Hetal Pandya
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
P Value ◽  
Diabetic Patients ◽  
Healthy Population ◽  
Type 2 Diabetic Patients ◽  
Serum Vitamin D ◽  
Type 2 Diabetic

Background: The current worldwide epidemic of diabetes mellitus is a serious health problem because of the high toll of vascular complications. Vitamin D deficiency as emerging epidemic have effect on pathophysiology of diabetes mellitus by various mechanisms, so we have taken up this study with aim to see effect of both high prevalent diseases on each other and to observe prevalence and pattern of vitamin D deficiency in diabetics.Methods: In this case-control study 70 type 2 diabetic patients were taken as cases and 70 healthy individuals as controls. All participants included in this study were subjected to complete history taking and clinical examination and routine laboratory Investigations were done for all participants. The data was analyse using appropriate statistical tests.Results: The prevalence of low vitamin D level (inclusive of insufficiency and deficiency) was 18.57% in healthy controls, while 84.29% in diabetic group. Mean level of vitamin D in cases was 25.73±7.27 while 34.55±5.17 in healthy population (p value <0.05). Vitamin D deficiency is more seen in uncontrolled diabetes patients. Inverse correlation was recorded between HbA1C and serum vitamin D level (r = - 0.281, p value = <0.001).Conclusions: Vitamin D deficiency is highly prevalent in diabetic patients as compare to normal healthy population. All patients of type 2 Diabetes patients must have screened for serum vitamin D level and if found deficient than it should be treated promptly with vitamin D supplements for better control of hyperglycaemia.

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