scholarly journals Retrospective Analysis of Prognostic Factors in Adult Glioblastoma Multiforme: A Single Institution Experience

2019 ◽  
Vol 0 (0) ◽  
pp. 1-6
Author(s):  
Mohamed Abd El Moumen ◽  
Lobna Ezz El Arab ◽  
Nesreen Mosalam ◽  
Ahmed Gaballah
Keyword(s):  
Prognostic Factors ◽  
Glioblastoma Multiforme ◽  
Retrospective Analysis ◽  
Single Institution

scholarly journals Prognostic factors in glioblastoma multiforme

2010 ◽  
Vol 29 (04) ◽  
pp. 121-125 ◽  
Author(s):  
Leonardo Welling ◽  
José Carlos Lynch ◽  
Celestino Pereira ◽  
Ricardo Andrade ◽  
Fabiana Polycarpo Hidalgo ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Glioblastoma Multiforme ◽  
Retrospective Analysis ◽  
Tumor Volume ◽  
Standard Treatment ◽  
Karnofsky Performance Status ◽  
Performance Status ◽  
Surgical Techniques ◽  
The Other ◽  
Tumor Removal

Abstract Objective: To study if the prognosis variables such as age, the Karnofsky Performance Status (KPS), extension of tumor removal by surgery, radiotherapy and tumor volume influenced the survival of patients with glioblastoma multiforme (GBM). Method: Retrospective analysis of GBM patients operated at Hospital dos Servidores do Estado between 1998 and 2008. Results: We could observe that age, the KPS and radiotherapy influenced the survival. The other variables did not have any prognosis implications. Conclusions: Despite many researches and many improvements regarding the diagnosis and the surgical techniques, the survival of patients with GBM has not changed in the last 30 years and is a therapeutic challenge. The surgical resection followed by radiotherapy is the standard treatment for patients with GBM. The importance of each variable in the patient's prognosis is still to be established in the multivariate analyzes.

scholarly journals Treatment Outcome and Prognostic Factors for Patients with Bone‐Only Metastases of Breast Cancer: A Single‐Institution Retrospective Analysis

2011 ◽  
Vol 16 (2) ◽  
pp. 155-164 ◽  
Author(s):  
Naoki Niikura ◽  
Jun Liu ◽  
Naoki Hayashi ◽  
Shana L. Palla ◽  
Yutaka Tokuda ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Treatment Outcome ◽  
Prognostic Factors ◽  
Retrospective Analysis ◽  
Single Institution

scholarly journals Prognostic factors in head and neck cancer: a 10-year retrospective analysis in a single-institution in Italy

2017 ◽  
Vol 37 (6) ◽  
pp. 458-466
Author(s):  
G. Cadoni ◽  
L. Giraldi ◽  
L. Petrelli ◽  
M. Pandolfini ◽  
M. Giuliani ◽  
...  
Keyword(s):  
Overall Survival ◽  
Head And Neck Cancer ◽  
Prognostic Factors ◽  
Head And Neck ◽  
Retrospective Analysis ◽  
Neck Cancer ◽  
Hazard Ratio ◽  
Single Institution

È stata condotta un’analisi retrospettiva su 482 pazienti con diagnosi di tumore testa-collo arruolati presso l’ ospedale “Agostino Gemelli” di Roma. L’associazione tra fattori demografici, clinici e comportamentali con la overall survival (OS), il rischio di ricorrenza ed il rischio di un secondo tumore primitivo è stata stimata usando gli Hazard Ratio (HR) e gli intervalli di confidenza al 95% (CIs). La OS considerando tutte le sedi tumorali è stata del 60%, mentre considerando le singole sedi tumorali è risultata del 49.0% per il cavo orale, 54.8% per l’orofaringe, 50.0% per l’ipofaringe e 63.4% per la laringe. Un’età avanzata alla diagnosi (HR = 1.04; 95% CI: 1.02-1.05) ed un avanzato stadio del tumore (HR = 2.00; 95% CI: 1.41-2.84) sono risultati fattori significativamente associati con la OS. Il rischio di ricorrenza è risultato associato con il consumo di alcolici (HR = 1.73; 95% CI: 1.00-2.97). Il rischio di sviluppare un secondo tumore primitivo è risutlato associato con uno stadio avanzato del tumore primario (HR = 2.75; 95% CI: 1.39-5.44) e con l’aver fumato per più di 40 anni (HR = 3.68; 95% CI: 1.10-12.30). In conclusione abbiamo notato che la OS differisce tra le sedi tumorali del tumore testa-collo. Lo stadio tumorale è risultato essere associato sia con la OS che con il rischo di sviluppare un secondo tumore primitivo. Il consumo di alcol e di tabacco sono risultati essere fattori prognostici, rispettivamente, per la ricorrenza e per l’insorgenza di un secondo tumore primitivo.

Prognostic Factors in Glioblastoma Multiforme 10 Years Experience of a Single Institution

2001 ◽  
Vol 177 (6) ◽  
pp. 283-290 ◽  
Author(s):  
Maarten C.C.M. Hulshof ◽  
Radboud W. Koot ◽  
Eric C. Schimmel ◽  
Fido Dekker ◽  
D. Andries Bosch ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Glioblastoma Multiforme ◽  
Single Institution

scholarly journals SURVIVALAND PROGNOSTIC FACTORS FOR GLIOBLASTOMA MULTIFORME: A RETROSPECTIVE SINGLE INSTITUTIONAL STUDY

2020 ◽  
pp. 1-3
Author(s):  
Maneet Gill ◽  
Chinmaya Srivastava ◽  
Sudhanshu Agarwal ◽  
Lokesh Gautam
Keyword(s):  
Overall Survival ◽  
Survival Analysis ◽  
Prognostic Factors ◽  
Glioblastoma Multiforme ◽  
Retrospective Analysis ◽  
Clinical Features ◽  
Median Survival ◽  
Survival Outcome ◽  
Patient Specific ◽  
Entire Cohort

OBJECTIVE The purpose of the present retrospective analysis was to present and discuss clinical features (Patient specific and tumour specific) and various prognostic factors that predict the survival of the patients with Glioblastoma multiforme (GBM) and to compare the results with pre-existing literature. MATERIALS &METHODS A single institutional data of 221 patients of GBM was reviewed from 2014 to 2018. Data regarding patients’ factor,tumour factor and survival analysis were collected and based on the above factor’s survival outcome was calculated. RESULTS A total of 221 patients were analysed. 197 patients underwent resection and 24 patients underwent biopsy (Open or stereotactic). Patients had a mean age of 56.5 years at the time of diagnosis. Median survival in patients < 50 years was 9.21 months and > 50 years was 4.56 months. The overall survival was 4.27% for the entire cohort at the end of two years. CONCLUSION In patients with GBM overall survival and prognosis remains dismal.Standard treatment includes resection followed bychemo-radiation which has improved the overall survivaloutcome. However, the prognosis continues to remains poor.

Surveillance for stage I testicular seminoma at a single institution in Japan: Retrospective analysis of prognostic factors for relapse.

2011 ◽  
Vol 29 (7_suppl) ◽  
pp. 234-234 ◽  
Author(s):  
K. Kakimoto ◽  
K. Takeda ◽  
T. Yoshida ◽  
M. Nakayama ◽  
Y. Arai ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Survival Rate ◽  
Retrospective Analysis ◽  
Vascular Invasion ◽  
Lymphatic Invasion ◽  
Rete Testis ◽  
Stage I ◽  
Single Institution ◽  
Testicular Seminoma ◽  
Beta Hcg

234 Background: Treatment options for clinical stage I seminoma include adjuvant radiotherapy (RT) as well as surveillance and adjuvant chemotherapy (CT). Data available from the surveillance, adjuvant RT and adjuvant CT series suggest that all treatment strategies achieve a complete cure in almost 100% of the patients with stage I testicular seminoma. The success of surveillance of patients with stage I nonseminomatous germ cell tumors and the establishment of curative CT for advanced disease have led to re-examination of the standard treatment approach. We report the results of a retrospective analysis of the prognostic factors for stage I testicular seminoma. Methods: We retrospectively reviewed the survey of 87 patients with stage I testicular seminoma who were admitted in an institution between January 1982 and January 2009. We examined if the following tumor characteristics could possibly predict the relapse: age at diagnosis, tumor size, pathological T (pT) stage, elevation of beta-hCG level and/or LDH level, invasion of the rete testis, vascular invasion and lymphatic invasion. The cause-specific survival rate was calculated using the Kaplan-Meier method. Results: During a median follow-up of 8.1 years (range, 1.2-25.7 years), 13 (14.9%) relapses were observed, with an actuarial 5-year relapse-free rate (RFR) of 87.9%. The univariate analysis showed that the following characteristics were not predictive of relapse: age at diagnosis (RFR: 89% [<36 years] vs. 88% [≥36 years]), tumor size (RFR: 90% [<5.6 cm(median)] vs. 85% [≥5.6 cm]), pT stage (RFR: 91% [pT = 1] vs. 84% [pT = 2 and pT = 3]), elevation of beta-hCG level (RFR: 89% [normal] vs. 87% [elevated]), invasion of the rete testis (RFR:90% [absent] vs. 80% [present]), vascular invasion (RFR:86% [absent] vs. 87% [present]), and lymphatic invasion (RFR: 88% [absent] vs. 87% [present]). The overall 5-year survival rate was 97%. Conclusions: Prognostic factors for relapse could not be identified in this retrospective analysis of the patients admitted in a single institution. To identify the prognostic factors for risk-adapted treatment for stage I testicular seminoma, we need to study a large sample population in Japan. No significant financial relationships to disclose.

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