scholarly journals Cistatina C como biomarcador Gold estándar para el diagnóstico de problemas renales agudos en caninos

2021 ◽  
Vol 16 (2) ◽  
pp. 76-102
Author(s):  
Johanna Marcela Moscoso Gama ◽  
Astrid Lorena Cuadros Losada ◽  
Dayana Katherine Rico Ruiz ◽  
Braian Julian Rodriguez Rodriguez
Keyword(s):  
Small Animal

Los caninos con lesiones renales tienen afectados distintos procesos tales como filtración, reabsorción y excreción que alteran la homeostasis. La medición de biomarcadores alternativos ha servido para el diagnóstico y pronóstico de daño renal, lo que ha servido para el médico veterinario, no solo por la oportunidad en el diagnóstico temprano sino por ejercicio preventivo. Uno de los marcadores que permite evaluar la tasa de filtración glomerular (TFG) es la concentración sérica de creatinina, ya que esta varía en proporciones inversas, por otro lado, se encuentra la creatinina (Ccr), siendo una buena herramienta para indicar el compromiso de la función glomerular, aunque esta no suele ser tan confiable, por sus altas interferencias al momento de medir. Por esto se ha postulado otros biomarcadores que dan un pronóstico más temprano y que permiten dar un tratamiento oportuno, entre ellos está la cistatina C, que presenta una baja variabilidad interindividual, ya que no genera uniones proteicas, no tiene secreción tubular y no se genera reabsorción tubular si no existe catabolismo de la proteína. El objetivo de esta revisión es presentar a la Cistatina C (CisC) como un biomarcador Gold estándar para el diagnóstico de problemas renales agudos en caninos, puesto que en medicina humana ya se ha establecido que la CisC tiene un mejor valor diagnóstico renal y de determinación de la TFG que la creatinina sérica, además de que tiene una constante producción y visibilidad en la concentración plasmática en situaciones de ausencia de variaciones de la TFG. Para la recolección de la información utilizada en esta revisión, se emplearon diversas fuentes como: PubMed, Scielo, Journal of Small Animal Practice, National Center for Biotechnology Information, en donde fueron seleccionados 50 artículos para realizar esta investigación.

Recommendations for Intensive Care Management in Small Animals Following Anaesthesia

1992 ◽  
Vol 05 (02) ◽  
pp. 66-70
Author(s):  
Karol Mathews ◽  
Doris Dyson
Keyword(s):  
Intensive Care ◽  
Care Management ◽  
Small Animal ◽  
Small Animals ◽  
Monitoring Equipment ◽  
Intensive Care Management ◽  
Good Communication

Intensive care management can be provided in a small animal facility by centralisation of emergency and monitoring equipment. Good communication between all personnel involved in the case ensures that staff are prepared for complications that could arise related to recovery from anaesthesia.

Continuous Blood-Sampling in small animal [18F]FDG-PET/CT measurements

2019 ◽  
Author(s):  
T Mann ◽  
BJ Krause ◽  
A Hawlitschka ◽  
J Stenzel ◽  
T Lindner ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Small Animal ◽  
Blood Sampling ◽  
Ct Measurements ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Image quality evaluation of a small animal PET scanner

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Andréa Vidal Ferreira ◽  
Rodrigo Modesto Gadelha Gontijo ◽  
Guilherme Cavalcante de Albuquerque Souza ◽  
Bruno Melo Mendes ◽  
Juliana Batista da Silva ◽  
...  
Keyword(s):  
Image Quality ◽  
Quality Evaluation ◽  
Small Animal ◽  
Small Animal Pet ◽  
Image Quality Evaluation ◽  
Animal Pet

Intestinal microbiota balance modulates host susceptibility to infection with enteric pathogenss

2007 ◽  
Vol 30 (4) ◽  
pp. 93
Author(s):  
I Sekirov ◽  
N Tam ◽  
M Robertson ◽  
C Lupp ◽  
B Finlay
Keyword(s):  
Intestinal Microbiota ◽  
Small Animal ◽  
Host Susceptibility ◽  
Morphological Development ◽  
Future Design ◽  
Susceptibility To Infection ◽  
Colonic Microbiota ◽  
Food Borne ◽  
Serovar Typhimurium ◽  
Intestinal Pathogens

Background: During our lifetimes we develop a very complex set of interactions with the multitude of microorganisms colonizing our bodies. In the gastrointestinal system, the microbiota is highly important for morphological development, nutrition, and protection against infectious diseases. The gastrointestinal pathogens, enterohemorrhagic and enteropathogenic Escherichia coli (EHEC and EPEC) and Salmonella enterica serovar Typhimurium (ST) are food-borne pathogens that cause much morbidity and mortality worldwide. Citrobacter rodentium (Cr) is a mouse pathogen that is used in small animal models to mimic EHEC and EPEC infections. Methods: We began to characterize the contribution of intestinal microbiota to the progression of these infections. Two main phyla comprise the majority of mouse intestinal microbiota: Bacteroidetes and Firmicutes. Bacteria from a number of additional phyla are also present in smaller numbers; among them γ-Proteobacteria class, belonging to Proteobacteria phylum, is note-worthy as this class harbours many intestinal pathogens, such as ST and Cr. The mouse intestinal microbiota was perturbed using tetracycline (Tet) and streptomycin (Sm) to increase the proportion of Bacteroidetes in the colonic microbiota, and using vancomycin (Vanc) to create a predominance of Firmicutes. The mice with this perturbed microbiota were infected with ST to investigate the resultant pathology and virulence characteristics, and any additional shifts in microbiota as a result of infection. Results: Treatment of mice with Sm and Vanc was found to decrease the resistance of mice to colonization with ST, while Tet-treated mice exhibited unchanged colonization resistance. Treatment of mice with gradually increasing doses of Sm, which gradually augmented the proportion of CFB bacteria in the microbiota, resulted in progressively increasing colonization of mice by ST, as well as a step-wise increase in the ST-induced typhlitis, associated with higher levels of inflammatory markers IL-6 and KC. The increasing levels of ST colonization following both Sm and Vanc treatment were associated with an increase in the proportion of γ-Proteobacteria in the cecal and colonic microbiota, as well as a decrease in the total bacterial numbers in both organs. Conclusions: It is evident that the intestinal microbiota plays a significant role in the host’s response to infection with enteric pathogens, and its composition and numbers are also affected by the offending bacteria. Elucidation of the details regarding the contribution of the microbiota to infectious disease progression will offer novel targets for the future design of superior prevention and treatment methods.

Radiation Safety in Small Animal Radiography

1972 ◽  
Vol 12 ◽  
pp. 147-150
Author(s):  
Lars-Erik Kangstrom ◽  
Albert Kiibus
Keyword(s):  
Radiation Safety ◽  
Small Animal

IMPROVING THE TECHNIQUE OF CYSTOSTOMY IN SMALL ANIMAL

2020 ◽  
Vol 242 (2) ◽  
pp. 93-96
Author(s):  
A.V. Kuznetsova ◽  
◽  
D.A. Arkhipova ◽  
F.V. Shakirova ◽  
◽  
...  
Keyword(s):  
Small Animal
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