INVESTIGATION OF THE EFFECT OF CHANGES IN GUT MICROFLORA AND PREVENTIVE TAKING OF PROBIOTICS ON THE FUNCTIONAL STATE OF THE STOMACH DURING ISOLATION STUDY SIRIUS-18/19

2021 ◽  
Vol 55 (1) ◽  
pp. 70-75
Author(s):  
V.K. Ilyin ◽  
◽  
B.V. Afonin ◽  
D.V. Komissarova ◽  
K.A. Shef ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Hydrochloric Acid ◽  
Functional State ◽  
Acid Production ◽  
Inhibitory Effect ◽  
Food Additive ◽  
Empty Stomach ◽  
Gut Microflora ◽  
The Moon

Investigations of the gastrointestinal tract functioning in isolation simulating a mission to the Moon and an experimental "space" diet showed changes in the gut microflora, an increase of the empty stomach juice and quickened evacuation. Probiotic beverage, a food additive, kept the gut microflora stable, and controlled juice volume in the empty stomach and evacuation. The inhibitory effect on evacuation consisted in increasing the hydrochloric acid production in the empty stomach.

scholarly journals Effect of Fermented Feed on the Microbial Population of the Gastrointestinal Tracts of Pigs

2001 ◽  
Vol 67 (7) ◽  
pp. 3071-3076 ◽  
Author(s):  
Ren� L. van Winsen ◽  
Bert A. P. Urlings ◽  
Len J. A. Lipman ◽  
Jos M. A. Snijders ◽  
David Keuzenkamp ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Significant Positive Correlation ◽  
Stomach Contents ◽  
Significant Negative Correlation ◽  
Inhibitory Effect ◽  
Positive Correlation ◽  
Fermented Feed ◽  
The Family ◽  
Colon And Rectum

ABSTRACT An in vivo experiment was performed with pigs to study the inhibitory effect of fermented feed on the bacterial population of the gastrointestinal tract. Results demonstrated a significant positive correlation between pH and lactobacilli in the stomach contents of pigs in dry feed as well as in the stomach contents of pigs fed fermented feed. Furthermore, a significant positive correlation between the pH and the numbers of bacteria in the familyEnterobacteriaceae in the contents of the stomach of pigs fed dry feed was found. In the stomach contents of pigs fed fermented feed, a significant negative correlation was found between the concentration of the undissociated form of lactic acid and the numbers of Enterobacteriaceae. The numbers ofEnterobacteriaceae in the contents of the stomach, ileum, cecum, colon, and rectum of pigs fed fermented feed were significantly lower compared with the contents of the stomach, ileum, caecum, colon, and rectum of pigs fed dry feed. The numbers of total lactobacilli were significantly higher in the stomach contents of pigs fed fermented feed and in the ileum contents of one pig group fed fermented feed compared with the contents of pigs fed dry feed. However, the influence of lactobacilli on numbers of Enterobacteriaceae could not be demonstrated. It was concluded that fermented feed influences the bacterial ecology of the gastrointestinal tract and reduces the levels of Enterobacteriaceae in the different parts of the gastrointestinal tract.

Sites of Organic Acid Production and Patterns of Digesta Movement in the Gastrointestinal Tract of Dogs

1979 ◽  
Vol 109 (9) ◽  
pp. 1592-1600 ◽  
Author(s):  
Charles A. Banta ◽  
Edgar T. Clemens ◽  
Mary M. Krinsky ◽  
Ben E. Sheffy
Keyword(s):  
Gastrointestinal Tract ◽  
Organic Acid ◽  
Acid Production ◽  
Organic Acid Production

Interdigestive Activity in the Gastrointestinal Tract

Physiology ◽  
1987 ◽  
Vol 2 (3) ◽  
pp. 101-103
Author(s):  
DF Magee
Keyword(s):  
Gastrointestinal Tract ◽  
Spontaneous Activity ◽  
Intestinal Tract ◽  
Empty Stomach ◽  
Intrinsic Activity ◽  
Base Line ◽  
Gastrointestinal Physiology

The empty stomach and intestinal tract show a great deal of apparently spontaneous activity, with regard to both motility and secretion. This intrinsic activity is cyclic and has caused problems for investigators of gastrointestinal physiology because it is difficult to establish a true base line for many experiments.

scholarly journals ACETYLCHOLINESTERASE INHIBITORY EFFECT OF 3-(1H-INDOL-3-YL)-1, 3-DIPHENYLPROPAN-1-ONE DERIVATIVES

2017 ◽  
Vol 10 (8) ◽  
pp. 83
Author(s):  
Manjunatha K S ◽  
Manu Cp ◽  
Satyanarayan Nd ◽  
Vinay Kn ◽  
Vineetha Ms ◽  
...  
Keyword(s):  
Hydrochloric Acid ◽  
Mode Of Action ◽  
Inhibitory Concentration ◽  
Inhibitory Effect ◽  
Considerable Degree ◽  
Ache Inhibition ◽  
Ache Inhibitors ◽  
Ellman’S Method ◽  
Inhibition Ability

Objective: The objective of the study is acetylcholinesterase (AChE) inhibitory effect of 3-(1H-indol-3-yl)-1, 3-diphenylpropan-1-one derivatives by Ellman’s method, physostigmine is used as positive control.Method: 3-(1H-indol-3-yl)-1, 3-diphenylpropan-1-one derivatives were synthesized by the addition of chalcone (0.25 g, 1 mmol), indole (0.12 g, 1 mmol) in ethanol (5 ml), and concentrated hydrochloric acid (5 mmol %). These earlier synthesized compounds were screened for AChE inhibitors by modifying Ellman’s method.Results: Among the tested compounds, 3a and 3j were found to be having more potential than other compounds with half maximal inhibitory concentration values of 13.64 and 14.3 μg/ml, respectively. Whereas, compounds 3c, 3e, 3g, and 3i exhibited an average AChE inhibition of 16.4, 17.9, 17.6, and 21.1 μg/ml, respectively.Conclusion: The compounds 3-(1H-indol-3-yl)-1, 3-diphenylpropan-1-one derivatives were found to be possible lead molecules in AChE inhibition and even though, the molecules were structurally dissimilar to that of the standard, still they exhibited a considerable degree of inhibition and encourage the researchers to look into the mode of action of their inhibition ability against AChE.

scholarly journals Inhibitory effect of Acacia hamulosa methanolic extract on the corrosion of mild steel in 1 M hydrochloric acid

2018 ◽  
Vol 32 (2) ◽  
pp. 323 ◽  
Author(s):  
A. Bader ◽  
U. Shaheen ◽  
M. A. S. Aborehab ◽  
Y. El Ouadi ◽  
A. Bouyanzer ◽  
...  
Keyword(s):  
Hydrochloric Acid ◽  
Mild Steel ◽  
Methanolic Extract ◽  
Inhibitory Effect
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