scholarly journals Seasonality, Epidemiology and Outcome of Congenital Diaphragmatic Hernia in South West of Iran

2017 ◽  
Vol 6 (2) ◽  
pp. 28 ◽  
Author(s):  
Masoud Dehdashtian ◽  
Shiva Bashirnejad ◽  
Arash Malekian ◽  
Mohammad Reza Aramesh ◽  
Mohammad Hasan Aletayeb

Introduction: The pathogenesis of congenital diaphragmatic hernia (CDH) is not clear. Risk factors including environmental factors have been implicated in the pathogenesis of few congenital anomalies. We aimed to assess the effect of season on the incidence of CDH and mortality rate in the southwest of Iran.Material and Methods: In this retrospective study, the records of 60 patients with CDH who were admitted at Neonatal Intensive Care Unit (NICU) of Imam Khomeini Hospital of Ahvaz, Iran were evaluated.Results: Assuming that all the neonates born with CDH in the region reach this hospital, overall CDH prevalence rate was 1.09 per 10 000 total births. Conceptions in spring and summer in this region had statistically significantly higher incidence of CDH. Survival rate in the series was 41.6%.Conclusion: Seasonal variation has impact on the incidence of CDH. Mortality rate in neonates with CDH is still very high.

2017 ◽  
Vol 33 (3) ◽  
pp. 524-532 ◽  
Author(s):  
Elizabeth B. Froh ◽  
Janet A. Deatrick ◽  
Martha A. Q. Curley ◽  
Diane L. Spatz

Background: Very little is known about the breastfeeding experience of mothers of infants born with congenital anomalies and cared for in the neonatal intensive care unit (NICU). Often, studies related to breastfeeding and lactation in the NICU setting are focused on the mothers of late preterm, preterm, low-birth-weight, and very-low-birth-weight infants. Congenital diaphragmatic hernia (CDH) is an anatomic malformation of the diaphragm and affects 1 in every 2,000 to 4,000 live births. Currently, there are no studies examining the health outcomes of infants with CDH and the effect of human milk. Research aim: This study aimed to describe the breastfeeding experience of mothers of infants with CDH cared for in the NICU. Methods: A prospective, longitudinal qualitative descriptive design was used. Phased interviews were conducted with a purposive sample of 11 CDH infant–mother dyads from a level 3 NICU in a children’s hospital. Results: Six themes emerged from the data: (a) hopeful for breastfeeding, (b) latching on . . . to the pump, (c) we’ve already worked so hard, (d) getting the hang of it—it’s getting easier, (e) a good safety net, and (f) finding a way that works for us. Conclusion: For this population of CDH infant–mother dyads, the term breastfeeding is not exclusive to direct feeding at the breast and the mothers emphasized the significance of providing their own mother’s milk through a combination of feeding mechanisms to their infants with CDH.


PRILOZI ◽  
2015 ◽  
Vol 36 (3) ◽  
pp. 83-89
Author(s):  
Silvana Naunova Timovska ◽  
Svetlana Cekovska ◽  
Katerina Tosheska-Trajkovska

Abstract Objective: Acute kidney injury is common condition in the neonatal intensive care unit and it is associated with poor outcome. The incidence of neonatal AKI is the highest one followed by adults and children, depending on different factors such as the gestational age, birth weight, contributing conditions and the facilities of the neonatal intensive care unit. The aim of the study was to determine the incidence, risk factors and the outcome of the neonatal acute kidney injury. Subjects and Methods: This was a clinical, prospective study that was performed in a referent NICU at the University Children′s Hospital in Skopje. All neonates admitted from January 2012 to December 20014 with documented acute kidney injury were included. The medical data records of the admitted neonates with AKI were analyzed. The material was statistically processed using methods of the descriptive statistics. Results: During the study period 770 newborn infants were admitted to the NICU and 50 (6.5%) infants developed acute kidney injury. The male to female ratio was 2.1:1. Most of the neonates involved in the study were neonates born at term (62%). Oliguric AKI was found in 28 cases (56%) and no oliguric in 22 cases (44%). The prevalence of prerenal, renal and post renal AKI were 78.5%, 19.5% and 2.0% respectively. Perinatal asphyxia was the most common predisposing factor for AKI and was evaluated in 38% of the cases with predominance of term infants and male. The mortality rate was 32% and was significantly higher in the group of patients with congenital heart diseases. Conclusion: AKI is a life threatening condition with still high mortality rate. Early recognition of the risk factors and the rapid effective treatment of the contributing conditions will reduce AKI in the neonatal period.


2017 ◽  
Vol 5 (2) ◽  
pp. 124
Author(s):  
Asep Deden Komara ◽  
Ezra Oktaliansah ◽  
Budiana Rismawan

Salah satu faktor risiko mortalitas pada neonatus yang menjalani operasi adalah regulasi cairan intraoperatif. Tujuan penelitian ini mengetahui angka mortalitas pada neonatus yang menjalani operasi berdasar atas kenaikan berat badan pascaoperasi yang dirawat di NICU. Metode penelitian adalah deskriptif dengan pendekatan retrospektif. Penelitian ini melibatkan 95 subjek penelitian, yaitu neonatus yang menjalani operasi dan dirawat di NICU RSHS Bandung selama tahun 2010‒2015. Data diambil dari rekam medis, pengambilan data mulai tanggal 1 Februari–29 Maret 2017.  Subjek dibagi tiga kelompok, yaitu neonatus yang telah menjalani prosedur operasi yang mengalami kenaikan berat badan pascaoperasi kurang 10% (I), neonatus yang menjalani prosedur operasi yang mengalami kenaikan berat badan 10‒20% (II), dan kelebihan berat badan ≥20% (III). Neonatus pacaoperasi dengan kenaikan berat badan  ≤10% sebanyak  46 pasien dan yang meninggal  sebanyak 10 pasien pada  kenaikan  berat badan 10‒20%  sebanyak 38 pasien, pasien yang meninggal sebanyak 23 pasien, angka mortalitasnya sebesar 60,5%, sedangkan  pada pasien dengan kenaikan berat badan sama dengan atau lebih dari 20% sebanyak 11 pasien atau 11,5% yang meninggal  sebanyak 10 pasien, angka mortalitasnya sebesar 90,9%. Simpulan angka mortalitas pasien neonatus yang menjalani operasi di RSHS dan pascaoperasi dirawat di NICU RSHS selama periode 2010–2015 adalah 45,3%. Kata kunci: Kenaikan berat badan, mortalitas, neonatus The Mortality Rate in Neonatal Patients which Underwent Surgical Procedures-Defined by the Escalation of Postoperative Weight and Those Who were Admitted in Neonatal Intensive Care Unit (NICU) One of the risk factors contributed to this number was the inappropriate management of intraoperative fluid resuscitation. The aim of this study is to understand the mortality rate in neonatal patients which underwent surgical procedures–defined by the escalation of postoperative weight and those who were admitted in NICU. The research method used in this study was a retrospective approach presented in a descriptive manner. The study involved 95 research subjects, which were neonatal patients which underwent surgical procedures and admitted in NICU RSHS Bandung from 2010‒2015. Data collection from Februari 1st–March 29th  2017. The research subjects were classified into three groups, neonatal patients which had escalation of weight postoperative less than 10% and underwent surgical procedure (I), neonatal patients which had escalation of weight postoperative ranging from 10‒20% and underwent surgical procedure (II), meanwhile consist of neonatal patients which had escalation of weight postoperative ≥20% and underwent surgical procedure (III). Result of the study showed there were 46 neonatal patients with 10% weight escalation and 10 out of 46 patients were ceased, meanwhile there were 38 neonatal patients with 10‒20% weight escalation and 23 out of 38 were ceased, and there were 11 neonatal patients with ≥20% weight escalation and 10 out of 11 were ceased. The conclusions of this study found a mortality rate of neonatal patients who underwent surgery and postoperative treated in  NICU RSHS during the period 2010 to 2015 is 45.3%. Key words: Weight gain, mortality, neonatal


Author(s):  
Alina Elena Gaiduchevici ◽  
Catalin Gabriel Cirstoveanu ◽  
Ana Mihaela Bizubac ◽  
Carmen Maria Heriseanu ◽  
Filip Cristina ◽  
...  

Background: This study presents the experience gained in the Newborn Intensive Care Unit (NICU) at “M. S. Curie” Emergency Clinical Hospital for Children in Bucharest after performing a series of bedside surgery interventions on newborns with congenital diaphragmatic hernia (CDH). We evaluate the advantages, complications, immediate and long-term outcome as well as the morbidity. Methods: We conducted a retrospective analysis of the data for all patients operated on-site be-tween 2011 and 2020, in terms of pre- and post-operative stability, procedures performed, com-plications and outcomes. Results: Our study is based on data from ten cases of newborns, term or small for gestation age with birthweights ranging from 2300 to 3300 grams, operated, on average, on the fifth day of life. The main reasons for operating on-site were the hemodynamical instability and the need to ad-minister inhaled Nitic Oxide (iNO) and HFOV ventilation. There were no unforeseen events dur-ing surgery, no immediate postoperative complications and no surgery related mortality. One noticed drawback was the unfamiliarity of the surgery team with the new operating environment. Conclusions: Our experience indicates that bedside surgery improves the likelihood of survival for critically ill neonates suffering from CDH. No immediate complications could be associated with this practice. Keywords: congenital diaphragmatic hernia, severe pulmonary hypertension, bedside surgery, NICU infrastructure


2021 ◽  
Vol 14 (7) ◽  
pp. e239181
Author(s):  
Kevin C McGann ◽  
Marjorie J Arca ◽  
Marsha Pulhamus ◽  
Michael H Livingston

A term male infant was born to a healthy 24-year-old mother with antenatally diagnosed liver-up, left congenital diaphragmatic hernia (CDH) and gastroschisis. The infant was stabilised in the neonatal intensive care unit and then underwent primary repair of the CDH via left subcostal incision and silo placement for the gastroschisis. Serial silo reductions were started postoperatively and umbilical flap closure for the gastroschisis was performed on day of life 6. The patient was weaned from respiratory support, started on enteral feeds, and discharged home at 1 month of age. He was weaned from supplemental nasogastric feeds by 6 weeks of age and is currently well and thriving at 11 months of age.


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