Milk Fermented with a 15-Lipoxygenase-1-Producing Lactococcus Lactis Alleviates Symptoms of colitis in a Murine Model

2015 ◽  
Vol 16 (5) ◽  
pp. 424-429 ◽  
Author(s):  
Tessalia Saraiva ◽  
Katia Morais ◽  
Vanessa Pereira ◽  
Marcela Azevedo ◽  
Clarissa Rocha ◽  
...  
Keyword(s):  
Lactococcus Lactis ◽  
Murine Model

scholarly journals Rotavirus VP6 protein mucosally delivered by cell wall-derived particles from Lactococcus lactis induces protection against infection in a murine model

PLoS ONE ◽  
2018 ◽  
Vol 13 (9) ◽  
pp. e0203700 ◽  
Author(s):  
C. Facundo Temprana ◽  
Marcelo H. Argüelles ◽  
Nicolás M. Gutierrez ◽  
Patricia A. Barril ◽  
Laura E. Esteban ◽  
...  
Keyword(s):  
Cell Wall ◽  
Lactococcus Lactis ◽  
Murine Model ◽  
Protection Against Infection ◽  
Rotavirus Vp6

Oral administration of Hsp65‐producing Lactococcus lactis attenuates allergic asthma in a murine model

2020 ◽  
Author(s):  
L.B. Lacerda ◽  
W.M. Rios ◽  
A.P. Masson ◽  
I.T. Brandão ◽  
T.M. Milani ◽  
...  
Keyword(s):  
Oral Administration ◽  
Allergic Asthma ◽  
Lactococcus Lactis ◽  
Murine Model

scholarly journals Lactococcus lactis carrying the pValac DNA expression vector coding for IL-10 reduces inflammation in a murine model of experimental colitis

2014 ◽  
Vol 14 (1) ◽  
pp. 73 ◽  
Author(s):  
Meritxell Zurita-Turk ◽  
Silvina del Carmen ◽  
Ana CG Santos ◽  
Vanessa B Pereira ◽  
Denise C Cara ◽  
...  
Keyword(s):  
Lactococcus Lactis ◽  
Murine Model ◽  
Expression Vector ◽  
Experimental Colitis ◽  
Vector Coding

scholarly journals Lactococcus lactisNCC 2287 Alleviates Food Allergic Manifestations in Sensitized Mice by Reducing IL-13 Expression Specifically in the Ileum

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Adrian W. Zuercher ◽  
Marietta Weiss ◽  
Sébastien Holvoet ◽  
Mireille Moser ◽  
Hélène Moussu ◽  
...  
Keyword(s):  
Drinking Water ◽  
Food Allergy ◽  
Lactococcus Lactis ◽  
Murine Model ◽  
Clinical Symptoms ◽  
Probiotic Strain ◽  
Oral Route ◽  
High Dose ◽  
Preventive Effect ◽  
Allergic Manifestations

Objective. Utilizing a food allergy murine model, we have investigated the intrinsic antiallergic potential of theLactococcus lactisNCC 2287 strain.Methods. BALB/c mice were sensitized at weekly intervals with ovalbumin (OVA) plus cholera toxin (CT) by the oral route for 7 weeks. In this model, an oral challenge with a high dose of OVA at the end of the sensitization period leads to clinical symptoms.Lactococcus lactisNCC 2287 was given to mice via the drinking water during sensitization (prevention phase) or after sensitization (management phase).Results.Lactococcus lactisNCC 2287 administration to sensitized mice strikingly reduced allergic manifestations in the management phase upon challenge, when compared to control mice. No preventive effect was observed with the strain.Lactococcus lactisNCC 2287 significantly decreased relative expression levels of the Th-2 cytokine, IL-13, and associated chemokines CCL11 (eotaxin-1) and CCL17 (TARC) in the ileum. No effect was observed in the jejunum.Conclusion/Significance. These results taken together designateLactococcus lactisNCC 2287 as a candidate probiotic strain appropriate in the management of allergic symptoms.

scholarly journals Oral immunization with Lactococcus lactis secreting attenuated recombinant staphylococcal enterotoxin B induces a protective immune response in a murine model

2013 ◽  
Vol 12 (1) ◽  
pp. 32 ◽  
Author(s):  
Giselli Fernandes Asensi ◽  
Nathalia Ferrari Fonseca de Sales ◽  
Fabiano Ferreira Dutra ◽  
Daniel Ferreira Feijó ◽  
Marcelo Torres Bozza ◽  
...  
Keyword(s):  
Immune Response ◽  
Lactococcus Lactis ◽  
Murine Model ◽  
Oral Immunization ◽  
Staphylococcal Enterotoxin ◽  
Protective Immune Response ◽  
Staphylococcal Enterotoxin B ◽  
Enterotoxin B

Evaluation of the Anti-Inflammatory Effect of Milk Fermented by a Strain of IL-10-Producing Lactococcus lactis Using a Murine Model of Crohn’s Disease

2011 ◽  
Vol 21 (3-4) ◽  
pp. 138-146 ◽  
Author(s):  
Silvina del Carmen ◽  
Alejandra de Moreno de LeBlanc ◽  
Gabriela Perdigon ◽  
Vanessa Bastos Pereira ◽  
Anderson Miyoshi ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Lactococcus Lactis ◽  
Murine Model ◽  
Anti Inflammatory ◽  
Inflammatory Effect
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