Valeriana jatamansi Constituent IVHD-valtrate As a Novel Therapeutic Agent to Human Ovarian Cancer: in vitro and in vivo Activities and Mechanisms

2013 ◽  
Vol 13 (4) ◽  
pp. 472-483 ◽  
Author(s):  
Xiaoguang Li ◽  
Tao Chen ◽  
Sheng Lin ◽  
Jing Zhao ◽  
Peizhan Chen ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Therapeutic Agent ◽  
Human Ovarian Cancer ◽  
Valeriana Jatamansi ◽  
Novel Therapeutic

scholarly journals In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer

2002 ◽  
Vol 86 (10) ◽  
pp. 1652-1657 ◽  
Author(s):  
R E Aird ◽  
J Cummings ◽  
A A Ritchie ◽  
M Muir ◽  
R E Morris ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cross Resistance ◽  
Human Ovarian Cancer ◽  
Arene Complexes

scholarly journals An In Vitro and In Vivo Investigation of the Antimetastatic Effects of a Chinese Medicinal Decoction, Erxian Decoction, on Human Ovarian Cancer Models

2012 ◽  
Vol 12 (4) ◽  
pp. 336-346 ◽  
Author(s):  
Ellie S. M. Chu ◽  
Stephen C. W. Sze ◽  
Ho P. Cheung ◽  
Qing Liu ◽  
Tzi B. Ng ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Human Ovarian Cancer ◽  
Erxian Decoction ◽  
Cancer Models

scholarly journals Structure Based Design and Synthesis of Peptide Inhibitor of Human LOX-12: In Vitro and In Vivo Analysis of a Novel Therapeutic Agent for Breast Cancer

PLoS ONE ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. e32521 ◽  
Author(s):  
Abhay kumar Singh ◽  
Ratnakar Singh ◽  
Farhat Naz ◽  
Shyam Singh Chauhan ◽  
Amit Dinda ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Therapeutic Agent ◽  
Peptide Inhibitor ◽  
Design And Synthesis ◽  
In Vivo Analysis ◽  
Novel Therapeutic

scholarly journals Antitumor properties of salinomycin on cisplatin-resistant human ovarian cancer cells in vitro and in vivo: Involvement of p38 MAPK activation

2013 ◽  
Vol 29 (4) ◽  
pp. 1371-1378 ◽  
Author(s):  
BEI ZHANG ◽  
XUEYA WANG ◽  
FENGFENG CAI ◽  
WEIJIE CHEN ◽  
ULI LOESCH ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
P38 Mapk ◽  
Ovarian Cancer Cells ◽  
Human Ovarian Cancer ◽  
Mapk Activation ◽  
Antitumor Properties

c-Met Antisense Oligodeoxynucleotides as a Novel Therapeutic Agent for Glioma: In Vitro and In Vivo Studies of Uptake, Effects, and Toxicity

2007 ◽  
Vol 141 (2) ◽  
pp. 284-288 ◽  
Author(s):  
Sheng-Hua Chu ◽  
Hong Zhang ◽  
Yan-Bin Ma ◽  
Dong-Fu Feng ◽  
Zhi-An Zhu ◽  
...  
Keyword(s):  
Therapeutic Agent ◽  
Antisense Oligodeoxynucleotides ◽  
In Vivo Studies ◽  
Novel Therapeutic

scholarly journals Platelets, Thrombocytosis, and Ovarian Cancer Prognosis: Surveying the Landscape of the Literature

2020 ◽  
Vol 21 (21) ◽  
pp. 8169
Author(s):  
Demetra H. Hufnagel ◽  
Gabriella D. Cozzi ◽  
Marta A. Crispens ◽  
Alicia Beeghly-Fadiel
Keyword(s):  
Ovarian Cancer ◽  
Wound Healing ◽  
Cancer Prognosis ◽  
Current Evidence ◽  
Vascular Integrity ◽  
Critical Components ◽  
Ovarian Cancer Prognosis ◽  
Novel Therapeutic

Platelets are critical components of a number of physiologic processes, including tissue remodeling after injury, wound healing, and maintenance of vascular integrity. Increasing evidence suggests that platelets may also play important roles in cancer. In ovarian cancer, thrombocytosis, both at the time of initial diagnosis and at recurrence, has been associated with poorer prognosis. This review describes current evidence for associations between thrombocytosis and ovarian cancer prognosis and discusses the clinical relevance of platelet count thresholds and timing of assessment. In addition, we discuss several mechanisms from in vitro, in vivo, and clinical studies that may underlie these associations and recommend potential approaches for novel therapeutic targets for this lethal disease.

Novel organo-osmium(ii) proteosynthesis inhibitors active against human ovarian cancer cells reduce gonad tumor growth in Caenorhabditis elegans

2021 ◽  
Vol 8 (1) ◽  
pp. 141-155
Author(s):  
Enrique Ortega ◽  
Francisco J. Ballester ◽  
Alba Hernández-García ◽  
Samanta Hernández-García ◽  
M. Alejandra Guerrero-Rubio ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Antitumor Activity ◽  
Tumor Growth ◽  
Cancer Cells ◽  
Ovarian Cancer Cells ◽  
Human Ovarian Cancer ◽  
Arene Complexes ◽  
C Elegans

Novel Os(ii) arene complexes with a deprotonated ppy or ppy-CHO C^N ligand have been synthesized to selectively act on cancer cells as proteosynthesis inhibitors in vitro and exert antitumor activity in vivo in C. elegans models.

In Vitro and In Vivo Demonstration of Human-Ovarian-Cancer Necrosis through a Water-Soluble and Near-Infrared-Absorbing Chlorin

2018 ◽  
Vol 61 (11) ◽  
pp. 5009-5019 ◽  
Author(s):  
Betsy Marydasan ◽  
Bollapalli Madhuri ◽  
Shirisha Cherukommu ◽  
Jedy Jose ◽  
Mambattakkara Viji ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Near Infrared ◽  
Water Soluble ◽  
Human Ovarian Cancer
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