ZnO@SnO2 Mixed Metal Oxide as an Efficient and Recoverable Nanocatalyst for the Solvent Free Synthesis of Hantzsch 1,4-Dihydropyridines

2019 ◽  
Vol 16 (2) ◽  
pp. 139-144 ◽  
Author(s):  
Bharatkumar M. Sapkal ◽  
Prakash K. Labhane ◽  
Shamrao T. Disale ◽  
Dhananjay H. More
Keyword(s):  
Metal Oxide ◽  
Metal Oxide Nanoparticles ◽  
Reaction Times ◽  
Solvent Free ◽  
Catalyst Loading ◽  
Mixed Metal Oxide ◽  
One Pot ◽  
Mixed Metal ◽  
Solvent Free Conditions ◽  
Three Component Reaction

An efficient synthesis of Hantzsch 1,4-dihydropyridines via a one-pot three-component reaction of ethyl acetoacetate, substituted aldehydes and ammonium acetate in the presence of ZnO@SnO2 mixed metal oxide nanoparticles under solvent-free conditions has been reported. Compare to the reported reactions, this method shows attractive aspects such as cleaner reaction profile, shorter reaction times, minimum catalyst loading and high yields. Isolated catalysts were reused for new reactions without considerable loss of their catalytic activity.

scholarly journals Efficient Synthesis of 1-Amidoalkyl-2-Naphthols by One-Pot, Three-Component Reaction under Solvent-Free Conditions

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Zahed Karimi-Jaberi ◽  
Marziyeh Jokar ◽  
S. Zoleykha Abbasi
Keyword(s):  
Trichloroacetic Acid ◽  
Reaction Times ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
One Pot Condensation ◽  
High Yields ◽  
Free Media

Two efficient and direct procedures have been developed for the preparation of 1-amidoalkyl-2-naphthols by a one-pot condensation of aldehydes, 2-naphthol, and amides in the presence of trichloroacetic acid or cobalt (II) chloride as catalyst. The reactions were carried out under solvent-free media. High yields, short reaction times, easy workup of the catalyst are advantages of these procedures.

scholarly journals An Efficient and Green Procedure for the Synthesis of 2,4,6-Triarylpyridines Using PPA-SiO2as a Reusable Heterogeneous Catalyst Under Solvent-Free Conditions

2012 ◽  
Vol 9 (4) ◽  
pp. 2037-2043 ◽  
Author(s):  
Abolghasem Davoodnia ◽  
Bahareh Razavi ◽  
Niloofar Tavakoli-Hoseini
Keyword(s):  
Heterogeneous Catalyst ◽  
Simple Procedure ◽  
Substantial Reduction ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
High Yields ◽  
Work Up

Silica gel-supported polyphosphoric acid (PPA-SiO2) was found to be highly efficient, eco-friendly and recyclable heterogeneous catalyst for the synthesis of 2,4,6-triarylpyridines through one-pot three-component reaction of acetophenone, aryl aldehydes, and ammonium acetate under solvent-free conditions. This method has several advantages, such as simple procedure with an easy work-up, short reaction times, and high yields. Furthermore, the catalyst could be recycled after a simple work-up, and used at least three times without substantial reduction in its catalytic activity.

scholarly journals Efficient, One-Pot Synthesis of Tetrahydrobenzo[a]xanthen-11-ones and Dibenzo[a,j]xanthenes Using Trichloroacetic Acid as a Solid Heterogeneous Catalyst Under Solvent-Free Conditions

2011 ◽  
Vol 8 (4) ◽  
pp. 1895-1899 ◽  
Author(s):  
Zahed Karimi Jaber ◽  
S. Zoleykha Abbasi ◽  
Baharak Pooladian ◽  
Marziyeh Jokar
Keyword(s):  
Heterogeneous Catalyst ◽  
Efficient Method ◽  
Trichloroacetic Acid ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Aryl Aldehydes ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
Free Media

A simple and efficient method have been described for the synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one derivatives employing a one-pot, three-component reaction of aryl aldehydes, 2-naphthol and dimedone in the presence of trichloroacetic acid under solvent-free conditions. Also the condensation of 2-naphthol with alkyl or aryl aldehydes in the presence of trichloroacetic acid under solvent-free media to afford the corresponding 14-aryl or alkyl -14H-dibenzo [a.j]xanthenes in excellent yields and short reaction times is described.

A one-pot three-component synthesis of novel α-sulfamidophosphonates under ultrasound irradiation and catalyst-free conditions

RSC Advances ◽  
2015 ◽  
Vol 5 (49) ◽  
pp. 39324-39329 ◽  
Author(s):  
Billel Belhani ◽  
Malika Berredjem ◽  
Marc Le Borgne ◽  
Zouhair Bouaziz ◽  
Jacques Lebreton ◽  
...  
Keyword(s):  
Reaction Times ◽  
Ultrasound Irradiation ◽  
Solvent Free ◽  
One Pot ◽  
Mild Conditions ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
Work Up

A one-pot synthesis of novel α-sulfamidophosphonates is described via a three-component reaction under ultrasound irradiation, catalyst-free and solvent-free conditions. The synthesis has mild conditions, short reaction times, good yields and simple work-up procedures.

One-pot Synthesis of Novel Thiophene Containing Aminonaphthols using Fe3O4 Nanoparticles as a Recyclable Heterogeneous Catalyst

2021 ◽  
Vol 10 ◽  
Author(s):  
Ganesh Pavale ◽  
M. M. V. Ramana ◽  
Poornima Acharya ◽  
Sarfaraz Shaikh
Keyword(s):  
Catalytic Activity ◽  
Metal Oxide ◽  
Fe3o4 Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Solvent Free ◽  
Precipitation Method ◽  
Synthetic Approach ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Wide Range

Background: Metal oxide and metal oxide nanoparticles are gaining significant importance due to their reusability and wide range of catalytic applications in many organic transformations. Objective: To report simple and efficient Fe3O4 catalyzed one-pot five-component reaction protocol to synthesize novel thiophene containing aminonaphthols under solvent-free conditions. Method: To prepare the Fe3O4 nanoparticles by facile and simple co-precipitation method and surface characterization was done using FT-IR, XRD, BET, SEM, and TEM analysis technique. Aminonaphthol derivatives bearing thiophene moiety were synthesized using Fe3O4 nanoparticles under solvent-free conditions. Results: The prepared nanoparticles are smaller in size (15nm) and can be easily detachable. It can be recycled and reused five times without any significant loss of catalytic activity with excellent yields in a short time. The existing protocol for synthesizing amino naphthol becomes feasible and attractive due to the reusability of the catalyst, excellent catalytic performance, and eco-friendly procedure. Conclusion: In conclusion, Fe3O4 nanoparticles provide a simple, efficient, and greener one-pot five-component synthetic approach to synthesize thiophene containing aminonaphthols. Excellent catalytic activity was perceived in a short reaction time without any co-catalyst or any other activator. Moreover, reusability of catalyst, high yields, and environmentally benign solvent-free condition are vital factors of this protocol.

scholarly journals Three-component reaction of β-keto esters, aromatic aldehydes and urea/thiourea promoted by caffeine, a green and natural, biodegradable catalyst for eco-safe Biginelli synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones derivatives under solvent-free conditions

2018 ◽  
Vol 83 (6) ◽  
pp. 673-684 ◽  
Author(s):  
Farzaneh Mohamadpour ◽  
Mojtaba Lashkari
Keyword(s):  
Biginelli Reaction ◽  
Reaction Times ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Solid Catalyst ◽  
One Pot ◽  
Keto Esters ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
High Yields

Caffeine was found to be a natural and green and biodegradable catalyst for the one-pot, three-component condensation Biginelli reaction of ?-keto esters, aromatic aldehydes and urea/thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones/thiones derivatives under solvent-free conditions. The remarkable features of this green procedure are high yields, short reaction times, simplicity of operation and work-up procedures, the availability and easy handling of this solid catalyst, avoidance of hazardous or toxic catalysts and organic solvents and economic availability of the catalyst.

scholarly journals Fe3O4@urea/HITh-SO3H as an efficient and reusable catalyst for the solvent-free synthesis of 7-aryl-8H-benzo[h]indeno[1,2-b]quinoline-8-one and indeno[2′,1′:5,6]pyrido[2,3-d]pyrimidine derivatives

2020 ◽  
Vol 18 (1) ◽  
pp. 648-662
Author(s):  
Shenghao Jiang ◽  
Macheng Shen ◽  
Fatima Rashid Sheykhahmad
Keyword(s):  
Electron Microscopy ◽  
Reaction Times ◽  
Solvent Free ◽  
Reusable Catalyst ◽  
Pyrimidine Derivatives ◽  
Magnetic Nanocatalyst ◽  
One Pot ◽  
X Ray ◽  
Solvent Free Conditions ◽  
Three Component Reaction

AbstractIn this study, Fe3O4@urea/HITh-SO3H MNPs as a new, efficient, and recyclable solid acid magnetic nanocatalyst was synthesized and characterized using various methods including Fourier transform infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy, transmission electron microscopy, vibrating sample magnetometry, energy-dispersive X-ray spectroscopy, and X-ray powder diffraction. After the characterization of this new magnetic nanocatalyst, it was efficiently utilized for the promotion of the one-pot synthesis of 7-aryl-8H-benzo[h]indeno[1,2-b]quinoline-8-one and indeno[2′,1′:5,6]pyrido[2,3-d]pyrimidine derivatives via three-component reaction of the 1,3-indanedione, aldehyde, and 1-naphthylamine/1,3-dimethyl-6-aminouracil under solvent-free conditions at 80°C. The procedure gave the desired heterocyclic structures in high-to-excellent yields and short reaction times. Also because of the magnetic nature of the nanocatalyst, it can be separated with an external magnetic field and reused at least six runs without any considerable decrease in the catalytic behavior.

Chlorosulfonic Acid Supported Piperidine-4-carboxylic Acid (PPCA) Functionalized Fe3O4 Nanoparticles (Fe3O4-PPCA): The Efficient, Green and Reusable Nanocatalyst for the Synthesis of Pyrazolyl Coumarin Derivatives under Solvent-Free Conditions

2019 ◽  
Vol 22 (2) ◽  
pp. 123-128
Author(s):  
Setareh Habibzadeh ◽  
Hassan Ghasemnejad-Bosra ◽  
Mina Haghdadi ◽  
Soheila Heydari-Parastar
Keyword(s):  
Carboxylic Acid ◽  
Fe3o4 Nanoparticles ◽  
High Efficiency ◽  
Reaction Times ◽  
Chlorosulfonic Acid ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Magnetic Nanocatalyst ◽  
One Pot ◽  
Solvent Free Conditions

Background: In this study, we developed a convenient methodology for the synthesis of coumarin linked to pyrazolines and pyrano [2,3-h] coumarins linked to 3-(1,5-diphenyl-4,5- dihydro-1H-pyrazol-3-yl)-chromen-2-one derivatives using Chlorosulfonic acid supported Piperidine-4-carboxylic acid (PPCA) functionalized Fe3O4 nanoparticles (Fe3O4-PPCA) catalyst. Materials and Methods:: Fe3O4-PPCA was investigated as an efficient and magnetically recoverable Nanocatalyst for the one-pot synthesis of substituted coumarins from the reaction of coumarin with a variety of aromatic aldehydes in high to excellent yield at room temperature under solvent-free conditions. The magnetic nanocatalyst can be easily recovered by applying an external magnet device and reused for at least 10 reaction runs without considerable loss of reactivity. Results and Conclusion: The advantages of this protocol are the use of commercially available materials, simple and an inexpensive procedure, easy separation, and an eco-friendly procedure, and it shows good reaction times, good to high yields, inexpensive and practicability procedure, and high efficiency.

A highly efficient and green approach for the synthesis of pyrimido[4,5-b]quinolines using N,N-diethyl-N-sulfoethanaminium chloride

2021 ◽  
Vol 76 (2) ◽  
pp. 85-90
Author(s):  
Abdolkarim Zare ◽  
Manije Dianat
Keyword(s):  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Catalyst Amount ◽  
Green Protocol ◽  
Highly Efficient ◽  
Green Approach ◽  
Solvent Free Conditions ◽  
The One ◽  
High Yields

Abstract A highly efficient and green protocol for the synthesis of pyrimido[4,5-b]quinolines has been described. The one-pot multicomponent reaction of dimedone with arylaldehydes and 6-amino-1,3-dimethyluracil in the presence of N,N-diethyl-N-sulfoethanaminium chloride ([Et3N–SO3H][Cl]) as an ionic liquid (IL) catalyst under solvent-free conditions afforded the mentioned compounds in high yields and short reaction times. Our protocol is superior to many of the reported protocols in terms of two or more of these factors: the reaction times, yields, conditions (solvent-free versus usage of organic solvents), temperature and catalyst amount.

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