Effect of Variable Doses of Paederia foetida L. Combat Against Experimentally- Induced Systemic and Topical Inflammation in Wistar Rats

2018 ◽  
Vol 14 (1) ◽  
pp. 70-79 ◽  
Author(s):  
Vikas Kumar ◽  
Gaurav Kaithwas ◽  
Firoz Anwar ◽  
Mahfoozur Rahman ◽  
Dinesh K. Patel ◽  
...  
2017 ◽  
Vol 49 (5) ◽  
pp. 528-536 ◽  
Author(s):  
K.O. Ajeigbe ◽  
W.M. Owonikoko ◽  
V. Egbe ◽  
I. Iquere ◽  
G. Adeleye

2012 ◽  
Vol 27 (7) ◽  
pp. 441-447 ◽  
Author(s):  
José Roberto Passarini Junior ◽  
Fernanda Oliveira de Gaspari de Gaspi ◽  
Lia Mara Grosso Neves ◽  
Marcelo Augusto Marreto Esquisatto ◽  
Gláucia Maria Tech dos Santos ◽  
...  

PURPOSE: To investigate the effects of Jatropha curcas L. seed oil and microcurrent stimulation on the healing of wounds experimentally induced in Wistar rats. METHODS: Forty-eight animals were divided into four groups: (A) control; (B) treated with microcurrent (10 µA/2 min); (C) treated with J. curcas seed oil, and (D) treated with J. curcas seed oil plus microcurrent. Tissues samples were obtained two, six, ten and 14 days after injury and submitted to structural and morphometric analyses. RESULTS: The animals of groups A and C showed similar responses in terms of repair area, total number of cells, number of newly formed blood vessels, epithelial thickness, and percentage of area occupied by mature collagen fibers. Significant differences in all parameters analyzed were observed between animals of groups B and D and the control 10 and 14 days after experimentally induced injury. The morphometric data confirmed the structural findings CONCLUSIONS: The application of J. curcas seed oil alone was not effective on experimental wound healing when compared to control, but microcurrent application alone or combined with the oil exerted significant differences in the parameters studied. These findings suggest that the positive results were due to microcurrent stimulation.


Author(s):  
Pallavi Khajuria Pratiksha Raghuwanshi ◽  
Aditi Lal Koul Ankur Rastogi ◽  
Dibyendu Chakarborty Vishav Pratap Singh ◽  
Sumeet Kour V.S. Wazir

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