Determination of Endocrine Disruptor Bisphenol-A leakage from Different Matrices of Dental Resin-Based Composite Materials

2021 ◽  
Vol 17 ◽  
Author(s):  
Naser F. Al-Tannak ◽  
Fawaz Alzoubi ◽  
Fatma M. Kareem ◽  
Ladislav Novotny

Background: Bisphenol A (BPA) derivatives monomers as resins are common components in dental restorative materials and materials used for orthodontic treatment. However, they are a source for BP-A leakage, which can affect adult and child health as an endocrine disruptor. Objective: This study aimed to investigate the level of BPA leakage from four selected weights (0.1, 0.2, 0.3, 0.4 mg) of five different resin combinations used in dental restorative materials. Method: The resin combinations were cured with light for 20 seconds, kept in 1 mL of acetonitrile, and sonicated for 30 minutes. Separation was achieved by using BEH C18 (1.7 μm, 2.1 x 100 mm) analytical column (Waters® Acquity UPLC) and a mobile phase composed of water and acetonitrile (68:32 v/v). Moreover, Waters® Xevo G2-SQToF coupled with Waters® Acquity UPLC system with binary Solvent Manager (I-Class) via electrospray ionization (ESI) interface was used to confirm peaks identities. Results: BPA was detected in all resin combinations and in all selected sample weights. However, BP-A was below the limit of quantification (LOQ) in all selected weights of the Filtek Z350 XT Universal Restorative System. The results show that BPA is still released from selected dental resin combinations available in the market despite the general concern about its potential adverse effects. Conclusion: Nevertheless, the amounts of BPA were within the acceptable levels indicated by the U.S. Environmental Protection Agency and the U.S. Department of Health and Human Services National Toxicology Program and represent a very small contribution to the total BPA exposure. The use of alternative materials such as high-viscosity glass ionomers, inorganic biomaterials, and ceramic would be ideal and healthier for adults and children.

Author(s):  
K. J. Chun ◽  
C. Y. Kim ◽  
J. Y. Lee

Dental restorative materials including amalgam, dental ceramic, gold alloy, dental resin, zirconia, and titanium alloy are used to reconstruct damaged teeth, as well as to recover their function. In this study, the mechanical properties of various dental restorative materials were determined using test specimens of identical shape and dimension under the same three-point bending test condition, and the test results were compared to enamel and dentin. The maximum bending force of enamel and dentin was 6.9 ± 2.1 N and 39.7 ± 8.3 N, and the maximum bending deflection was 0.12 ± 0.02 mm and 0.25 ± 0.03 mm, respectively. The maximum bending force of amalgam, dental ceramic, gold alloy, dental resin, zirconia, and titanium alloy were 1.9 ± 0.4 N, 2.7 ± 0.6 N, 66.9 ± 4.1 N, 2.7 ± 0.3 N, 19.0 ± 2.0 N, and 121.3 ± 6.8 N, respectively, and the maximum bending deflection was 0.20 ± 0.08 mm, 0.28 ± 0.07 mm, 2.53 ± 0.12 mm, 0.37 ± 0.05 mm, 0.39 ± 0.05 m, and 2.80 ± 0.08 mm, respectively. The dental restorative materials that possessed greater maximum bending force than that of enamel were gold alloy, zirconia, and titanium alloy. Gold alloy and titanium alloy had greater maximum bending force than dentin. The dental restorative materials that possessed greater maximum bending deflection than that of enamel were all of the dental restorative materials, and the dental restorative materials that possessed greater maximum bending deflection than that of dentin were all of the dental restorative materials except amalgam. The appropriate dental restorative materials for enamel are gold alloy and zirconia and for dentin is gold alloy concerning the maximum bending force and the maximum bending deflection. These results are expected to aid dentists in their choice of better clinical treatment and to contribute to the development of dental restorative materials that possess properties that are most similar to the mechanical properties of dental hard tissue.


Polymers ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 332 ◽  
Author(s):  
Loredana Tammaro ◽  
Anna Di Salle ◽  
Anna Calarco ◽  
Ilenia De Luca ◽  
Francesco Riccitiello ◽  
...  

Resin-based composites are widely used as dental restorative materials due to their excellent properties. They must have high modulus, high hardness, and be chemically inert while minimizing moisture uptake. To fulfill these higher standard prerequisites and properties, continuous improvements in each of their components are required. This study develops novel composites with multiple biofunctions. Light-cured Bis-GMA/TEGDMA dental resin (RK)/layered double hydroxide intercalated with fluoride ions (LDH-F)/calcium bentonite (Bt) hybrid composites were prepared. The loading ratio of LDH-F to Bt was varied, ranging from 2.5/2.5 to 10/10 parts per hundred RK and structural, mechanical, and biological properties were studied. The incorporation of even small mass fractions (e.g., 2.5 wt% of LDH-F and 2.5 wt% of Bt) in RK dental resin significantly improved the mechanical properties of the pristine resin. The synthetized materials showed antibacterial and antibiofilm effects against three bacterial strains isolated from healthy volunteers’ saliva (Streptococcus spp., Bacteroides fragilis, and Staphylococcus epidermidis) without affecting its ability to induce dental pulp stem cells differentiation into odontoblast-like cells. The capability to balance between the antibiofilm activity and dental pulp stem cells differentiation in addition with improved mechanical properties make these materials a promising strategy in preventive and restorative dentistry.


2003 ◽  
Vol 11 (3) ◽  
pp. 162-167 ◽  
Author(s):  
Linda Wang ◽  
Paulo Henrique Perlatti D'Alpino ◽  
Lawrence Gonzaga Lopes ◽  
José Carlos Pereira

A wide variety of dental products that are launched on the market becomes the correct selection of these materials a difficult task. Although the mechanical properties do not necessarily represent their actual clinical performance, they are used to guide the effects of changes in their composition or processing on these properties. Also, these tests might help somehow the clinician to choose once comparisons between former formulations and new ones, as well as, with the leading brand, are highlighted by manufactures. This paper presents a review of the most important laboratory tests. In this manner, the knowledge of these tests will provide a critical opinion related to the properties of different dental materials.


1982 ◽  
Vol 40 (2) ◽  
pp. 113-120 ◽  
Author(s):  
Kjeld Kr. Skjørland ◽  
Arne Hensten-Pettersen ◽  
Dag ørsta-Vik ◽  
Karl-Johan Söderholm

2021 ◽  
Vol 12 (4) ◽  
pp. 164
Author(s):  
MORTEZA SHARIFI ◽  
REZA KHODADADI ◽  
MOHAMMAD TAVAKOLI ◽  
MASOUMEH BEHDARVANDI

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