Use Of External Intrathecal Infusion Pumps In The Management Of Septic Complications: A Case Report

2015 ◽  
Vol 15 (4) ◽  
pp. 293-296
Author(s):  
Riccardo Marvulli ◽  
Pierpaolo Chiumarulo ◽  
Mattia Nisi ◽  
Laura Barulli ◽  
Gianfranco Megna ◽  
...  
2019 ◽  
Vol 48 (1) ◽  
pp. 244-252 ◽  
Author(s):  
Klaus Weber ◽  
Felix Weber ◽  
Monica Longo ◽  
Yoshimasa Okazaki ◽  
Nils Warfving ◽  
...  

Two beagle dog strains were used in a 14-day intrathecal infusion study for a small molecule test article. A moderate number of Renaut bodies (RBs) were observed in the sciatic nerves of control and test article–treated adult animals as early as 1 day after test article infusion (ie, 5 days after catheter implantation in the lumbar cistern). In most cases, the sciatic nerve was affected unilaterally, apparently in association with extended lateral recumbency on one side. The lighter beagle strain (Marshall), and especially the females (which weighed less than age-matched Marshall males), developed more RBs. In contrast, neither females nor males of the larger strain (Harlan) developed any nerve lesions. These data support the hypothesis that RBs develop following mechanical stress to sciatic nerves, suggest that this change may develop fairly quickly following an insult, and demonstrate that different dog strains exhibit strain-specific nerve changes.


2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Asem Saleh ◽  
Abdelnasir Kibeida ◽  
Elsaid Amin ◽  
Abdalla Khalil ◽  
Rafat Abu Shakra ◽  
...  

Postoperative septic complications of hemorrhoids surgical interventions are rare, but very serious with high mortality rate. Early diagnosis and prompt therapy are essential to save patient’s life. There are a good number of articles and case reports about these septic complications. We are presenting a case report of a prostatic abscess caused by extended spectrum beta lactamase (ESBL) producing Klebsiella pneumoniae after hemorrhoidopexy. Our patient was a healthy middle aged Saudi male who has no significant medical history apart from morbid obesity and recurrent urinary tract infections. ESBL producing K. pneumoniae could be detected only after aspiration of the prostatic abscess, but proper antibiotic was introduced intravenously on admission before culture of aspirate of the abscess was available. Antibiotic was continued for 30 days and abscess resolved completely. In our electronic search, we could not find any case report of prostatic abscess after stapled hemorrhoidopexy caused by ESBL producing organism. This is an additional challenge for treating physicians as these organisms are sensitive only to one group of antibiotics (carbapenem group).


2021 ◽  
Vol 82 (02) ◽  
pp. e11-e16
Author(s):  
Shujhat Khan ◽  
Giulio Anichini ◽  
Areeb Mian ◽  
Haider Kareem ◽  
Nelofer Syed ◽  
...  

AbstractWe present a case report of a 51-year-old left-handed male with a background of human papillomovairus 16-positive tonsil squamous cell carcinoma presenting with tonic-clonic seizure and a radiological diagnosis of secondary metastatic deposits. These were initially treated with stereotactic radiosurgery and subsequently with surgery. Surgical resection was performed under general anesthesia with right-sided temporal and parietal approaches. Both the parietal and temporal deposits were removed, while the intraventricular mass was intentionally left to avoid postoperative deficits. Adjuvant radiotherapy and chemotherapy were administered postoperatively. The patient experienced a satisfactory recovery postoperatively and was reoperated for recurrence 4 months later. He maintained a good quality of life and an excellent performance status throughout, but unfortunately he passed away in November 2018 due to septic complications. This case history stresses the difficulty in managing squamous cell carcinomas (SCC) with brain metastatic deposits. There are no current guidelines about the management of patients presenting with such a rare condition. More data are thus desirable to better define treatment guidelines and protocols when SCC brain metastases are present.


Neurosurgery ◽  
2010 ◽  
Vol 66 (2) ◽  
pp. E402-E403 ◽  
Author(s):  
Brandon G. Rocque ◽  
A. Leland Albright

Abstract OBJECTIVE Intrathecal infusion using an implantable pump is a common method of delivering medication for spasticity or chronic pain. The classic site for placement of the pump is in the abdominal wall. In some patients, there are confounding factors that make placement of an abdominal pump impractical. The purpose of this study was to report the implantation of Synchromed II pumps (Medtronic, Inc, Minneapolis, Minnesota) in the infraclavicular fossa. METHODS Four patients, aged 13 to 33 years, underwent infraclavicular placement of a Synchromed II infusion pump. In one patient, severe scoliosis and hip joint contractures precluded placement of the pump in the traditional position. Another patient had several ostomies on the abdominal wall, leaving no place for the pump. In a third, a combination of scoliosis and ostomy rendered the abdomen inappropriate for pump placement. RESULTS In 3 patients, a 20-mL pump was placed in the infraclavicular fossa. In the fourth, a 40-mL pump was placed in the left infraclavicular fossa. All patients tolerated the operation well. There were no postoperative reports of local pain or discomfort. One patient died from unrelated respiratory compromise several months after pump placement. At last follow-up (average of 11 months), the pumps were functioning well, and there were no wound-related complications. Selected pre- and postoperative photographs are presented. CONCLUSION The infraclavicular fossa is a viable alternative to the abdomen as the site for placement of a drug infusion pump.


2021 ◽  
Vol 70 (4) ◽  
pp. 135-140
Author(s):  
Andrey N. Plekhanov ◽  
Vitaly F. Bezhenar ◽  
Fedor V. Bezhenar ◽  
Tatyana A. Epifanova

Despite the lack of information in the medical literature on endometrioid disease complicated by infectious and inflammatory diseases, past community-acquired pneumonia caused by the new coronavirus infection may cause purulent-septic complications of endometriosis. The effect of the virus on endometrioid cysts was hematogenous in this clinical case. The information presented in this report can help clinicians in conducting differential diagnostics in patients with a history of endometriosis and previous SARS-CoV-2, establishing a diagnosis, as well as determining the tactics of examination and treatment.


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