scholarly journals Azzopardi Phenomenon in a Non-neoplastic Phthisical Eye: A Case Report

2021 ◽  
Vol 15 (1) ◽  
pp. 288-291
Author(s):  
Wasee Tulvatana ◽  
Panitee Luemsamran ◽  
Roy Chumdermpadetsuk ◽  
Somboon Keelawat
Keyword(s):  
Histopathological Examination ◽  
Retinal Vessel ◽  
Internal Limiting Membrane ◽  
Congenital Nystagmus ◽  
Systemic Steroid ◽  
Exudative Retinal Detachment ◽  
Poor Vision ◽  
Laser Iridotomy ◽  
Intraocular Tumors ◽  
Phthisis Bulbi

Objective: The Azzopardi phenomenon, known as the deoxyribonucleic acid deposition on various structures due to cellular necrosis, has never been reported in non-neoplastic eyes. Methods: We report a case of a 48-year-old man who had congenital nystagmus with poor vision in both eyes, presented with decreased vision and photophobia in his left eye. An exudative retinal detachment was found, which did not respond to systemic steroid treatment. Glaucoma due to occlusio pupillae was later developed. Laser iridotomy and anti-glaucoma medications decreased intraocular pressure to an acceptable level. Vision in the left eye gradually deteriorated during the 10-year clinical course. Evisceration was finally performed due to persistent dull aching ocular pain along with signs of ocular hypotony Results: Histopathological examination showed phthisis bulbi and focal nodular retinal gliosis. The Azzopardi phenomenon was found at the retinal vessel walls, within the retinal layers and along the internal limiting membrane. There was neither evidence of intraocular tumors nor foreign bodies. Conclusion: This case demonstrated that the Azzopardi phenomenon could be present in a non-neoplastic eye with a longstanding disease that proceeds to phthisis bulbi.

scholarly journals Successful Treatment of Toxic Epidermal Necrolysis More Than 70% Body Surface Area Involved with Immunosuppressive Therapy and Amniotic Membrane Graft in Cornea

1970 ◽  
Vol 22 (1) ◽  
pp. 50-52
Author(s):  
Md Rokon Uddin ◽  
Motahar Hossain Bhuiyan ◽  
Farjana Akhtar ◽  
Md Abu Baker ◽  
AKM Akramuzzaman
Keyword(s):  
Surface Area ◽  
Body Surface Area ◽  
Amniotic Membrane ◽  
Body Surface ◽  
Histopathological Examination ◽  
Tear Film ◽  
Electrolyte Imbalance ◽  
Systemic Steroid ◽  
College Hospital ◽  
Corneal Erosion

A 19 years young boy presented with papulo-vesicular lesions with necrosis over face, trunk upper and lower extremities; erosions and ulcerations over mucous membrane of eyes, mouth and genetalia. Lesions involved more than 70% of body surface area. Medical history was significant that was taking carbamazepine for epilepsy. On histopathological examination lymphatic infiltration at the dermoeidermal junction (DEJ) with necrosis of keratinocytes that some areas in full thickness. Management done in Enam Medical College Hospital (EMCH) in general ward with correction of fluid and electrolyte imbalance. Systemic steroid used in immunosuppressive dose and patient epidermal regrowth occur within 22-24 days. Main problem at that time gradual loss of vision, recurrent corneal erosion syndrome and tear film deficiency. Ophthalmology department of EMCH done amniotic membrane graft dry eye and corneal erosion. DOI: 10.3329/medtoday.v22i1.5608 Medicine Today Vol.22(1) 2010. 50-52

scholarly journals Histopathological examination of internal limiting membrane surface after scraping with diamond-dusted membrane scraper

2009 ◽  
Vol 88 (7) ◽  
pp. e293-e294 ◽  
Author(s):  
Akito Hirakata ◽  
Makoto Inoue ◽  
Kazuhiro Oshitari ◽  
Annabelle A. Okada ◽  
Toshiyuki Nagamoto ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Membrane Surface ◽  
Internal Limiting Membrane

scholarly journals Hydatid cyst of the orbit in a young Nigerian female: a case report

2018 ◽  
Vol 51 (4) ◽  
pp. 204-206
Author(s):  
Oluyemi Fasina ◽  
Olabiyi G Ogun
Keyword(s):  
Case Report ◽  
Hydatid Cyst ◽  
Young Patient ◽  
Cystic Lesion ◽  
Unusual Case ◽  
Histopathological Examination ◽  
Excision Biopsy ◽  
Poor Vision ◽  
Excised Tissue

Objective: To report an unusual case of orbital hydatid cyst successfully managed by surgical excision.Case report: A 33-year-old female presented with gradual protrusion of the left eye associated with poor vision, cosmetic embarrassment and watering. She had excision biopsy of an encapsulated cystic lesion with cheesy tissue and serous content. Orbital hydatid cyst due to echinococcosis was confirmed at histopathological examination of the excised tissue. She subsequently became pregnant hence, could not undergo post-operative antihelminthic treatment, but was managed conservatively with no recurrence after five years of regular follow-up.Conclusion: Orbital hydatid cyst should be considered as a differential in a young patient presenting with unilateral proptosisFunding: NoneKeywords: Echinococcosis, Hydatid cyst, Orbit, Nigerian, Proptosis

Optic nerve invasion of non-juxtapapillary uveal melanoma: a rare occurrence

2020 ◽  
Vol 13 (6) ◽  
pp. e234610
Author(s):  
Abhimanyu Sharma ◽  
Dilip K Mishra ◽  
Swathi Kaliki
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Uveal Melanoma ◽  
Histopathological Examination ◽  
Bulbar Conjunctiva ◽  
Clinical Indicators ◽  
Poor Vision ◽  
Tumour Extension ◽  
Systemic Metastasis ◽  
Nerve Tumour

A 44-year-old man presented with complaints of pain and discomfort in his left eye (OS). On examination, he had bare perception of light in OS and had a diffuse pigmented mass lesion in the nasal quadrant of the bulbar conjunctiva, associated with neovascularisation of the iris and iridocyclitis, with no fundus view. Intraocular pressure OS was 40 mm Hg. B-scan ultrasonography OS revealed an intraocular mass with thickened sclerochoroidal complex. A clinical diagnosis of OS ciliochoroidal melanoma with extraocular extension was made. He underwent OS extended enucleation with implant. Histopathological examination confirmed the diagnosis of ciliochoroidal melanoma with tumour extension into the optic nerve posteriorly and the extrascleral tissues anteriorly. There was no evidence of systemic metastasis. Even in a case of non-juxtapapillary uveal melanoma, poor vision and high intraocular pressure are clinical indicators of optic nerve tumour invasion.

Retinal vessel oxygen saturation is affected in uveitis associated with Vogt-Koyanagi-Harada disease

2019 ◽  
pp. bjophthalmol-2018-313719
Author(s):  
Ahmed M Abu El-Asrar ◽  
Abdulrahman F AlBloushi ◽  
Priscilla W Gikandi ◽  
Sveinn Hákon Hardarson ◽  
Einar Stefánsson
Keyword(s):  
Oxygen Saturation ◽  
Retinal Vessel ◽  
Oxygen Metabolism ◽  
Posterior Uveitis ◽  
Exudative Retinal Detachment ◽  
Healthy Controls ◽  
Chorioretinal Atrophy ◽  
Sunset Glow Fundus ◽  
And Gender ◽  
Vkh Disease

AimsTo discover whether retinal vessel oxygen metabolism is affected in uveitis associated with Vogt-Koyanagi-Harada (VKH) disease.Methods41 patients with VKH disease (82 eyes) and 12 healthy subjects (24 eyes) matched in age and gender were prospectively evaluated. Retinal oxygen saturation and vessel calibre were measured with a non-invasive spectrophotometric retinal oximeter (Oxymap T1).ResultsIn healthy controls, mean arteriolar oxygen saturation (%) was 93.8±5.9 and venular saturation was 60.1±5.8. In acute VKH uveitic phase associated with exudative retinal detachment (n=12), arteriolar and venular oxygen saturation values were 104.7±7.8 and 67.9±7.7, respectively, and both are significantly higher than the healthy group (p<0.001; p=0.001, respectively). In patients with VKH disease who recovered after immunosuppressive therapy and restored normal anatomy without ‘sunset glow fundus’ (n=13), oximetry values were 96.4±9.6 and 61.6±7.5, respectively, similar to healthy controls. In patients with ‘sunset glow fundus’ and chorioretinal atrophy (n=16), saturation levels were 88.6±7.8 and 50.0±13.1, respectively, significantly lower than healthy controls (p=0.02; p=0.003, respectively). These patients also had significantly smaller diameter of retinal arterioles and venules compared with controls (p=0.035; p=0.001, respectively).ConclusionsRetinal oxygen metabolism is altered in uveitis associated with VKH disease. Oxygen saturation profile is abnormal in acute uveitic phase of the disease and returns to normal in those who recover with normal fundus appearance, but not in eyes that suffer permanent anatomical damage with ‘sunset glow fundus’ and chorioretinal atrophy. Retinal oximetry may be of value in evaluating vascular and metabolic aspects of posterior uveitis.

Gentle endodiathermy of retinal vessels to mark paravascular posterior retinal breaks in highly myopic eyes

2017 ◽  
Vol 28 (3) ◽  
pp. 344-346
Author(s):  
Giuseppe D’Amico Ricci ◽  
Antonio Pinna ◽  
Francesco Boscia ◽  
Giancarlo Sborgia ◽  
Ermete Giancipoli
Keyword(s):  
Simple Technique ◽  
Retinal Vessel ◽  
Internal Limiting Membrane ◽  
Retinal Vessels ◽  
Retinal Break ◽  
Ilm Peeling ◽  
Retinal Breaks ◽  
Flow Restoration ◽  
Pars Plana ◽  
Air Exchange

Purpose: To show a new method to highlight posterior paravascular retinal breaks, responsible for posterior retinal detachment in highly myopic eyes, by gentle endodiathermy on the nearby retinal vessel, in areas of patchy chorioretinal atrophy. Methods: A standard 25-gauge (25-G) 3-port pars plana vitrectomy with internal limiting membrane (ILM) peeling was performed. A gentle endodiathermy was applied on the vessel close to the retinal break until a clear withe spot became visible. This spot was used as a landmark to identify the retinal break after fluid-air exchange. Results: The retina was attached after a single operation and no retinal redetachment was reported. A complete blood flow restoration in the treated vessel was documented with fluorescein angiography after 5 days. Conclusions: This simple technique may help the vitreoretinal surgeon to identify paravascular retinal breaks after fluid-air exchange. No damage to the retinal vessels undergoing endodiathermy was observed.

scholarly journals Acute Stromal Keratitis Following the Vitrectomy for the Treatment of Myopic Tractional Maculopathy in Lupus

2021 ◽  
Vol 20 (3) ◽  
pp. 129-133
Author(s):  
Tae Yeon Kim ◽  
So Hee Kim ◽  
Youna Choi ◽  
Seung Kwon Choi ◽  
Jae Jung Lee ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Corneal Edema ◽  
Internal Limiting Membrane ◽  
Systemic Steroid ◽  
High Dose ◽  
Hand Motion ◽  
Immune Mediated ◽  
Before And After ◽  
Stromal Keratitis ◽  
Punctate Keratitis

Purpose: To report a case of acute stromal keratitis after vitrectomy for the treatment of myopic tractional maculopathy in a lupus patient.Case summary: A lupus patient who were treated with low dose steroid complained of decreased visual acuity due to myopic tractional maculopathy with fovea detachment. No evidence of intraocular inflammation was observed. The best-corrected visual acuity (BCVA) was 20/40. We performed the vitrectomy and removal of epiretinal membrane and internal limiting membrane. BCVA of 20/80 at day 1 decreased to hand motion at day 5. Severe corneal edema and superficial punctate keratitis that were observed did not improve three days after the anti-herpetic treatment. Based on this, we diagnosed her as immune-mediated acute stromal keratitis in lupus, and treated with oral methylprednisolone of 20 mg. The corneal edema improved rapidly following high dose systemic steroid. Myopic fovea detachment also improved. Improvement of BCVA was limited to 20/80 at six months, compared to the baseline one.Conclusions: We observed the development of acute stromal keratitis after vitrectomy for the myopic tractional maculopathy in the patient with lupus. High dose systemic steroid improved this corneal complication. Increased dose of systemic steroid should be considered before and after vitrectomy in lupus patients.

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

A Case of Parathyroid Carcinoma Visualized on Tc-99m-Sestamibi Scintigraphy

1997 ◽  
Vol 36 (07) ◽  
pp. 256-258 ◽  
Author(s):  
G. F. Fueger ◽  
S. Lax ◽  
Reingard Aigner
Keyword(s):  
Parathyroid Carcinoma ◽  
Histopathological Examination ◽  
Parathyroid Tissue ◽  
Sestamibi Scintigraphy ◽  
Parathyroid Adenomas ◽  
Mibi Scintigraphy

SummaryRecent studies indicate that Tc-99m-Sestamibi (MIBI, DuPont Pharma) is a useful tracer for detecting parathyroid adenomas. We present a patient with focal Tc-99m-MIBI uptake in parathyroid carcinoma which has only been described once before (1). Tc-99m-MIBI scintigraphy may be considered for diagnosing pathological parathyroid tissue. But presently the histopathological examination only allows the differentiation between adenoma and carcinoma.

TO FIND OUT ELECTRO-CARDIOGRAPHIC CHANGES & ECHO CHANGES IN ALUMINIUM PHOSPHIDE AND ETHYLENE DIBROMIDE POISONING

2020 ◽  
Vol 4 (10) ◽  
Author(s):  
Hemant Nargawe ◽  
Sumeet Sisodiya
Keyword(s):  
Biochemical Analysis ◽  
Histopathological Examination ◽  
Common Finding ◽  
Histopathological Changes ◽  
Ethylene Dibromide ◽  
Medical College ◽  
Aluminium Phosphide ◽  
Urine Examination ◽  
Cardiovascular Involvement ◽  
Careful Clinical Examination

Background & Method: The study was conducted in the Department of Medicine Shyam Shah Medical College and Associated Sanjay Gandhi Memorial Hospital, Rewa (M.P). History was followed by a careful clinical examination i.e. cardiovascular, respiratory and gastrointestinal and nervous system. Investigations had done included routine haematological examination, Biochemical analysis, urine examination, ECG, 2 D. Echo & Histopathological examination was done. Result: ST-T changes were most common finding in Aluminium phosphide poisoning in relation to mortality. However hyperkalemia was the most ominous finding associated with 100% mortality, ECG finding in EDB was normal ECG. The most ominous finding was arrhythmia which was associated with 100% mortality. Survivors of ethylene dibromide poisoning echocardiography was normal in 11 (84.61%) followed by pericardial effusion in 2 (15.38%) patients. Conclusion: Noteworthy finding was absence of correlation between cardiovascular involvement, histopathological changes and ECG findings. It was seen that even if ECG showed normal pattern there were significant histopathological changes in heart. Keywords: electro-cardiographic, Aluminium phosphide, ethylene dibromide & poisoning.

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