Sexually Transmitted Co-infections in Persons Living with HIV

Author(s):  
Ana Paula Ferreira Costa ◽  
Marcos Gonzaga dos Santos ◽  
Ricardo Ney Oliveira Cobucci
HIV ◽  
2020 ◽  
pp. 89-98
Author(s):  
Ronnie M. Gravett ◽  
Jeanne Marrazzo

Sexually transmitted infections (STIs) significantly impact persons living with HIV and occur at relatively high incidence among persons living with HIV. Bacterial STIs, namely, chlamydia, gonorrhea, and syphilis, have increased tremendously since the advent of safe and effective antiretroviral therapy. Thus, while persons living with HIV are living much longer and healthier lives, many are experiencing a higher burden of STIs. The majority of STIs are asymptomatic, which raises challenges in screening and diagnosis and consequently the potential for delayed treatment. Taking a sexual history including sexual practices, partners, and symptoms should be a part of routine care of persons living with HIV. Annual screening for STIs is essential and should be more frequent as determined by sexual history. Prompt treatment can prevent further morbidity and adverse outcomes.


HIV ◽  
2020 ◽  
pp. 259-270
Author(s):  
Fariba Younai

Oral manifestations are among the earliest presentations of HIV infection. They appear during the course of HIV disease progression and immune deterioration and also in association with many sexually transmitted infections. In the era of effective retroviral therapies, HIV-related oral soft tissue lesions are seen in less frequently, and their presence may indicate undiagnosed HIV infection or treatment failure. Patients living with HIV and AIDS continue to experience salivary gland abnormalities, such as xerostomia, periodontal disease, and sexually transmitted human papilloma virus infection, which can increase their risk of developing oropharyngeal cancer. In addition to conventional adult gingivitis and periodontitis in persons living with HIV with immune recovery, unique features of severe periodontal disease can be associated with poorly controlled HIV.


Author(s):  
Jeffrey Edwards ◽  
Avery Hinds ◽  
Nyla Lyons ◽  
Jonathan Edwards ◽  
Shauntelle Quammie ◽  
...  

A chart review study of the sexually transmitted infection (STI) prevalence among persons living with HIV (PLHIV) was conducted among STI clinic attendees in Trinidad between January 2012 and December 2012. Data were abstracted from client records to obtain the clinical and the laboratory diagnoses of STIs. Descriptive and bivariate analyses were conducted, and factors significantly associated with the presence of a STI were assessed using multiple logistic regression. During this period, 385 PLHIV were seen; 104 (27.0%) were newly HIV diagnosed and 281 (73.0%) had a known history of HIV infection; 135 (35.1%) were diagnosed with a STI. Patients with known HIV infection were more likely to be diagnosed with a STI than those who were newly diagnosed (odds ratios: 6.99; 95% confidence interval: 3.79-12.89). The STI prevalence was high among PLHIV in Trinidad, identifying them as a critical target group for public health interventions to prevent the spread of HIV and STIs.


2019 ◽  
Author(s):  
Jenevieve Opoku ◽  
Rupali K Doshi ◽  
Amanda D Castel ◽  
Ian Sorensen ◽  
Michael Horberg ◽  
...  

BACKGROUND HIV cohort studies have been used to assess health outcomes and inform the care and treatment of people living with HIV disease. However, there may be similarities and differences between cohort participants and the general population from which they are drawn. OBJECTIVE The objective of this analysis was to compare people living with HIV who have and have not been enrolled in the DC Cohort study and assess whether participants are a representative citywide sample of people living with HIV in the District of Columbia (DC). METHODS Data from the DC Health (DCDOH) HIV surveillance system and the DC Cohort study were matched to identify people living with HIV who were DC residents and had consented for the study by the end of 2016. Analysis was performed to identify differences between DC Cohort and noncohort participants by demographics and comorbid conditions. HIV disease stage, receipt of care, and viral suppression were evaluated. Adjusted logistic regression assessed correlates of health outcomes between the two groups. RESULTS There were 12,964 known people living with HIV in DC at the end of 2016, of which 40.1% were DC Cohort participants. Compared with nonparticipants, participants were less likely to be male (68.0% vs 74.9%, <i>P</i>&lt;.001) but more likely to be black (82.3% vs 69.5%, <i>P</i>&lt;.001) and have a heterosexual contact HIV transmission risk (30.3% vs 25.9%, <i>P</i>&lt;.001). DC Cohort participants were also more likely to have ever been diagnosed with stage 3 HIV disease (59.6% vs 47.0%, <i>P</i>&lt;.001), have a CD4 &lt;200 cells/µL in 2017 (6.2% vs 4.6%, <i>P</i>&lt;.001), be retained in any HIV care in 2017 (72.9% vs 59.4%, <i>P</i>&lt;.001), and be virally suppressed in 2017. After adjusting for demographics, DC Cohort participants were significantly more likely to have received care in 2017 (adjusted odds ratio 1.8, 95% CI 1.70-2.00) and to have ever been virally suppressed (adjusted odds ratio 1.3, 95% CI 1.20-1.40). CONCLUSIONS These data have important implications when assessing the representativeness of patients enrolled in clinic-based cohorts compared with the DC-area general HIV population. As participants continue to enroll in the DC Cohort study, ongoing assessment of representativeness will be required.


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