Does Adriamycine, Cytoxan with Taxol Treatment Affect FBS and Lipid Profile in Breast Cancer Patients

2016 ◽  
Vol 8 (5) ◽  
Author(s):  
Simin Hemati ◽  
Mansour Siavash Dastjerdi ◽  
Minu Jelvan
Keyword(s):  
Breast Cancer ◽  
Lipid Profile ◽  
Cancer Patients ◽  
Breast Cancer Patients

Serum Lipid Profile of Breast Cancer Patients

2009 ◽  
Vol 12 (4) ◽  
pp. 332-338 ◽  
Author(s):  
W.K.B.A. Owiredu ◽  
S. Donkor ◽  
B. Wiafe Adda ◽  
N. Amidu
Keyword(s):  
Breast Cancer ◽  
Lipid Profile ◽  
Cancer Patients ◽  
Serum Lipid ◽  
Serum Lipid Profile ◽  
Breast Cancer Patients

scholarly journals Assessment of cardiotoxicity in hormone positive postmenopausal breast cancer patients receiving aromatase inhibitors

2019 ◽  
Vol 9 (1) ◽  
pp. 11
Author(s):  
Reham M. Faheim ◽  
Eman A. El-Shaarawy ◽  
Dina A. Salem ◽  
Rehab G. Shaaban
Keyword(s):  
Breast Cancer ◽  
Blood Pressure ◽  
Lipid Profile ◽  
Cancer Patients ◽  
Aromatase Inhibitors ◽  
Hormone Receptor ◽  
Postmenopausal Breast Cancer ◽  
P Value ◽  
Breast Cancer Patients ◽  
Hormone Receptor Positive

Background: Aromatase inhibitors (AIs) represent an effective endocrine treatment for hormone receptor-positive postmenopausal breast cancer patients with early stage or metastatic disease.Objective: Assessment of Cardiotoxicity in Hormone positive Postmenopausal Breast Cancer Patients receiving AIs (upfront orswitch therapy).Methods: This cross sectional study included 123 postmenopausal breast cancer patients presented to the Clinical Oncology Department, Ain Shams University (Cairo, Egypt) in the interval from August 2016 to June 2017 with hormone receptor positive receiving Aromatase Inhibitors, To assess cardiotoxicity in these patients, they were subjected to blood pressure and lipid profile measurement, electrocardiography (ECG), and electrocardiography (ECHO) and classified into patients had Nolvadex then A.I (arm 1) and others had upfront A.I (arm 2).Results: The age of patients ranged from 41 years to 85 years with mean age of 61 years. Seventy one patients (57.7%) showed cardiotoxicity as assessed by ECHO. They showed significant correlation with rising age above 62 years, IHD, history of HTN and DM (p value: .001, .001, .017 and 0.035 respectively). However, correlation between cardiotoxity and blood pressure changes, lipid profile changes and ECG findings and ECHO changes in switch therapy and upfront A.I were not statistically significant (p value = .275, .116, .081 and .761 respectively).Conclusion: Assessment of cardiotoxicity in hormone positive postmenopausal breast cancer patients receiving Aromatase Inhibitors showed evidence of cardiotoxicity in half the patients (57.7%) as detected by ECHO only. They showed statistically non significant correlations either recievied switch therapy or upfront A.I.

scholarly journals Assessment of Estradiol, Progesterone and Lipid Profile among Breast Cancer Patients in Ethiopia: Hospital-based Comparative Cross-Sectional Study

2021 ◽  
Author(s):  
Etagegn Tadesse ◽  
Daniel Seifu ◽  
Menakath Menon ◽  
Wondmagegnehu Tigeneh ◽  
Teka Obsa ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lipid Profile ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Healthy Controls ◽  
Breast Cancer Patients ◽  
Sectional Study ◽  
Serum Progesterone ◽  
Cross Sectional ◽  
Progesterone Metabolism

Abstract Background Breast cancer is the most often diagnosed type of cancer and the leading cause of death worldwide. Estrogen, also known as estradiol, influences progesterone metabolism and modifies lipid metabolism. Thus, steroid hormone and lipid profile levels for breast cancer patients must be evaluated. However, this has yet to be explored and used for therapy in Ethiopia. As a result, the present study at Tikur Anbessa Specialized Hospital attempted to assess serum estrogen, progesterone, and lipid profile levels in breast cancer patients and healthy controls. Methods A hospital-based comparative cross-sectional study was conducted on a total of 80 participants (40 newly diagnosed breast cancer patients and 40 healthy control females). A convenient sampling method was used to recruit the study participants. Steroid hormones and lipid profile were determined using immunoassays and an enzymatic colorimetric technique, respectively. SPSS version 20.0 was used for statistical analysis, and p-values of 0.05 were considered statistically significant. Results When compared to healthy controls, the mean serum progesterone, TC, and HDL-C levels in breast cancer patients were considerably lower, while estradiol, TG, and LDL-C levels were insignificantly higher. Conclusions Breast cancer may be to blame for changes in progesterone, estradiol, and lipid profile levels, which can lead to secondary problems.

Effect of aromatase inhibitors on the lipid profile of postmenopausal breast cancer patients

2010 ◽  
Vol 5 (2) ◽  
pp. 245-254 ◽  
Author(s):  
Christos J Markopoulos ◽  
Alexandra K Tsaroucha ◽  
Helen J Gogas
Keyword(s):  
Breast Cancer ◽  
Lipid Profile ◽  
Cancer Patients ◽  
Aromatase Inhibitors ◽  
Postmenopausal Breast Cancer ◽  
Breast Cancer Patients

scholarly journals LIPID PROFILE AND ITS SIGNIFICANCE IN BREAST CANCER

2020 ◽  
Vol 8 (10) ◽  
pp. 1241-1248
Author(s):  
Sharmin Arif ◽  
◽  
Fauzia Abdus Samad ◽  
Syed Abdus Samad ◽  
Asif Riaz Khan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lipid Profile ◽  
Cancer Patients ◽  
Morbidity And Mortality ◽  
Control Group ◽  
Breast Cancer Patients ◽  
Control Groups ◽  
Common Cancer ◽  
And Control ◽  
The Relationship

Background: According to WHO, breast cancer is the most common cancer in the women worldwide, soearly diagnosis is the best way to reduce its morbidity and mortality. Among various risk factors, the relationship between serum lipid profile and breast cancer is still unclear. Therefore, this study was conducted to evaluate this relationship. Methodology: Prospective, descriptive observational study with a comparative study designconducted at Fauji Foundation Hospital, Rawalpindi between November 2018 to April 2019. Results: 140 patients were divided into two groups i.e. cases and controls. Both groups were equally sub divided based on menstrual status. Independent student t-test was applied for comparison between the groups. BMI was significantly higher in the study group as compared to control group (p=0.002). Serum TG and LDL levels were higher in breast cancer patients (p= 0.032 and p=0.07 respectively). Cholesterol level was not statistically different in any group (p= >0.05). Higher HDL levels were seen in pre-menopausal cases (p=0.004) but there was no statistical difference when studied across cases and control groups. Conclusion: As breast cancer is the most common tumor in females, so early diagnosis is the key to reduce its morbidity and mortality. In this study, higher BMI, TG and LDL levels were seen in breast cancer patients as compared to controls. So, it may be concluded that BMI and dyslipidemia have some role in the etiology of breast cancer.

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