scholarly journals Construction of Viral Vectors for Cell Type-specific CRISPR Gene Editing in the Adult Mouse Brain

BIO-PROTOCOL ◽  
2019 ◽  
Vol 9 (16) ◽  
Author(s):  
Hiroshi Yamaguchi ◽  
Luis de Lecea
Keyword(s):  
Mouse Brain ◽  
Viral Vectors ◽  
Gene Editing ◽  
Adult Mouse ◽  
Cell Type ◽  
Adult Mouse Brain ◽  
Cell Type Specific

scholarly journals KAT3-dependent acetylation of cell type-specific genes maintains neuronal identity in the adult mouse brain

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Michal Lipinski ◽  
Rafael Muñoz-Viana ◽  
Beatriz del Blanco ◽  
Angel Marquez-Galera ◽  
Juan Medrano-Relinque ◽  
...  
Keyword(s):  
Mouse Brain ◽  
Adult Mouse ◽  
Cell Type ◽  
Adult Mouse Brain ◽  
Neuronal Identity ◽  
Cell Type Specific

Regional and cell-type specific distribution of HDAC2 in the adult mouse brain

2012 ◽  
Vol 218 (2) ◽  
pp. 563-573 ◽  
Author(s):  
Zhi-Gang Yao ◽  
Ling Zhang ◽  
Lan Huang ◽  
Hua Zhu ◽  
Ying Liu ◽  
...  
Keyword(s):  
Mouse Brain ◽  
Adult Mouse ◽  
Cell Type ◽  
Adult Mouse Brain ◽  
Specific Distribution ◽  
Cell Type Specific

scholarly journals Cell-Type-Specific Gene Expression Profiling in Adult Mouse Brain Reveals Normal and Disease-State Signatures

Cell Reports ◽  
2019 ◽  
Vol 26 (9) ◽  
pp. 2477-2493.e9 ◽  
Author(s):  
Nicolas Merienne ◽  
Cécile Meunier ◽  
Anne Schneider ◽  
Jonathan Seguin ◽  
Satish S. Nair ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Mouse Brain ◽  
Expression Profiling ◽  
Adult Mouse ◽  
Specific Gene ◽  
Cell Type ◽  
Adult Mouse Brain ◽  
Specific Gene Expression ◽  
Cell Type Specific

scholarly journals Molecularly distinct astrocyte subpopulations spatially pattern the adult mouse brain

2018 ◽  
Author(s):  
Mykhailo Y. Batiuk ◽  
Araks Martirosyan ◽  
Thierry Voet ◽  
Chris P. Ponting ◽  
T. Grant Belgard ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Synaptic Transmission ◽  
Axon Guidance ◽  
Mouse Brain ◽  
Adult Mouse ◽  
Synapse Formation ◽  
Cell Type ◽  
Adult Mouse Brain ◽  
Numerous Cell ◽  
The Central Nervous System

Astrocytes are a numerous cell type of the central nervous system. They perform many important functions in synapse formation and maintenance, control of local homeostasis and modulation of synaptic transmission. However, the degree to which specialist astrocyte subtypes fulfil these specific tasks is currently unclear. Here we use single cell transcriptomics to demonstrate that astrocytes, even those lying within the same region of adult mouse brain, show distinct molecular and spatial profiles, with profound implications for local CNS functions, including axon guidance, synaptogenesis and synaptic transmission.

scholarly journals A cell type‐specific expression map of NCoR1 and SMRT transcriptional co‐repressors in the mouse brain

2020 ◽  
Vol 528 (13) ◽  
pp. 2218-2238 ◽  
Author(s):  
Attilio Iemolo ◽  
Patricia Montilla‐Perez ◽  
I‐Chi Lai ◽  
Yinuo Meng ◽  
Syreeta Nolan ◽  
...  
Keyword(s):  
Mouse Brain ◽  
Cell Type ◽  
Specific Expression ◽  
Cell Type Specific Expression ◽  
A Cell ◽  
Cell Type Specific
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