Serum level of prostate specific antigen in users of a clinical laboratory of Novo Horizonte, São Paulo

This study aims to analyze the enteroparasitic occurrence in children from 0 to 12 years old consulted at the University of western São Paulo Clinical Laboratory, Presidente Prudente, SP, Brazil, in relation to the socioeconomic profile of the attended children. Stool samples were examined and a questionnaire was applied with the objective of knowing the patient's age, sex, medical attendance, characteristic of the habitation, provisioning of water, dejection and domestic waste fates, use of footwear and clinical signs. The software EPI INFO 6 (Version 6.04b) was used for the elaboration of the data bank structure and analysis after previous data codification. Among 1,000 children analyzed, as many as 21.3% presented some kind of parasite. The most frequent protozoan was Giardia lamblia (7.3%) followed by Entamoeba coli (3.9%). The most frequent helminth was Enterobius vermicularis (1.9%) followed by Hymenolepis nana (0.5%). The most frequent protozoan association was Giardia lamblia / Entamoeba coli (0.9%).

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Applying machine learning to assist the diagnosis of COVID-19 from blood and urine exams

10.5753/eniac.2021.18258 ◽

2021 ◽

Author(s):

Jessica Almeida dos Santos ◽

Lilian Berton

Keyword(s):

Clinical Laboratory ◽

Screening Method ◽

Sao Paulo ◽

High Rate ◽

World Health ◽

São Paulo ◽

Infected People ◽

Large Populations ◽

Low Incidence ◽

Health Organization

The COVID-19 pandemic declared in March 2020 by the World Health Organization (WHO) challenged the health system of several countries with the growing number of infected people. During the pandemic's peak in Europe, the low incidence of infection in South Korea drew the international community's attention, since not long ago that country was considered the epicenter of the pandemic outside its origin, in China. The mass testing protocol and tracing policies were pointed out as the formula for South Korean success, however, in view of the high demand and little supply of diagnostic tests for COVID-19 in the market, this strategy proved to be unfeasible to be implemented mainly in countries with large populations and with few financial resources, such as Brazil. There is also the aggravating factor regarding the effectiveness of the tests currently available, especially the rapid serology test with a high rate of false negatives. In order to offer a screening method for the application of tests, this work aims to develop a predictive model for assisting the identification of COVID-19 infection in suspected patients based on data from clinical laboratory examinations, such as blood count and urine tests. The data used comes from three sources in Sao Paulo and are hosted in the COVID-19 Data Sharing/BR Repository, a shared database of Sao Paulo Research Foundation (FAPESP). The work also proposes a comparison between balanced × imbalanced dataset and traditional × ensemble algorithms for this problem.

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Assessment of serum level of prostate-specific antigen adjusted for the transition zone volume in early detection of prostate cancer

International braz j urol ◽

10.1590/s1677-55382005000200008 ◽

2005 ◽

Vol 31 (2) ◽

pp. 137-146 ◽

Cited By ~ 3

Author(s):

Marcos D. Ferreira ◽

Walter J. Koff

Keyword(s):

Prostate Cancer ◽

Serum Level ◽

Early Detection ◽

Prostate Specific Antigen ◽

Transition Zone ◽

Specific Antigen

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Serum level of prostate-specific antigen in diabetic patients in Basrah, Iraq

Nigerian Postgraduate Medical Journal ◽

10.4103/npmj.npmj_174_17 ◽

2017 ◽

Vol 24 (4) ◽

pp. 240 ◽

Cited By ~ 1

Author(s):

JasimN Al-Asadi ◽

LamiaM Al-Naama ◽

MuhannadM Abdul-Kareem ◽

FawziC Mashkoor

Keyword(s):

Serum Level ◽

Prostate Specific Antigen ◽

Specific Antigen ◽

Diabetic Patients

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Skene's Gland Adenocarcinoma with Increased Serum Level of Prostate-Specific Antigen

Gynecologic Oncology ◽

10.1006/gyno.1994.1294 ◽

1994 ◽

Vol 55 (2) ◽

pp. 304-307 ◽

Cited By ~ 55

Author(s):

Mark K. Dodson ◽

William A. Cliby ◽

Gary L. Keeney ◽

Mark F. Peterson ◽

Karl C. Podritz

Keyword(s):

Serum Level ◽

Prostate Specific Antigen ◽

Specific Antigen

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Within the context of good clinical laboratory practices evaluation of measurement uncertainty of Thyroid Stimulating Hormone and Prostate Specific Antigen parameters

Turkish Journal of Biochemistry ◽

10.5505/tjb.2014.49358 ◽

2014 ◽

Author(s):

Sembol Turkmen Yildirmak

Keyword(s):

Measurement Uncertainty ◽

Prostate Specific Antigen ◽

Clinical Laboratory ◽

Specific Antigen ◽

Thyroid Stimulating Hormone ◽

Stimulating Hormone

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Evaluation of prostate specific antigen level in different age group of Patients in Eastern part of Nepal

Journal of Nobel Medical College ◽

10.3126/jonmc.v5i1.15748 ◽

2016 ◽

Vol 5 (1) ◽

pp. 14-19

Author(s):

Rupesh Kumar Shreewastav ◽

Chandra Prakash Gaire ◽

Ashima Ghimire ◽

Prashant Kumar Shah ◽

Arambam Giridhari Singh

Keyword(s):

Prostate Specific Antigen ◽

Clinical Laboratory ◽

Specific Antigen ◽

College Teaching ◽

Mean Value ◽

Prostate Specific Antigen Level ◽

Age Group ◽

Antigen Level ◽

Medical College ◽

Normal Individuals

Background A study was conducted to evaluate Prostate specific antigen (PSA) level in different age group of patients in Nobel Medical College Teaching Hospital (NMCTH), Biratnagar, Eastern Nepal.Material and Methods A total of 1870 male patients (age 51-88), attending OPD in different departments of NMCTH, were sent to Clinical Laboratory Services for estimation of Prostate specific antigen from 1st January 2013 to 30thJune 2014 and recruited for this study after Institutional ethical approval. Blood serum of these patients was tested for Prostate specific antigen level by Chemiluminescence Immunoassay (CLIA). Mean value and standard deviation were calculated using Student’s two–tailed t–test. Analysis of data was performed using one– way ANOVA. Results are considered statistically significant if p ≤0.05.Results Out of 1870 patients, 178 patients showed significantly higher level of PSA in their serum when compared to normal individuals. Out of this 178, 37 were from age group of 51-60, 51 were from age group of 61-70, 42 were from age group of 71-80 and 48 were from age group of 81-88. The remaining 1692 patients were having PSA within normal limit. PSA was found to be elevated up to a maximum of 34.5 ng/ml in patient. PSA level of <4 ng/ml was considered normal for this study.Conclusion This study, thus determines the diagnostic level of PSA, in different age group of patients comparing with normal individuals in eastern Part of Nepal that can help in diagnosis, prognosis and management of prostate cancer.Journal of Nobel Medical College Volume 5, Number 1, Issue 8, January-July 2016, 14-19

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RELATIONSHIP BETWEEN P53 EXPRESSION AND PSA SERUM

Indonesian Journal of Urology ◽

10.32421/juri.v19i2.56 ◽

2012 ◽

Vol 19 (2) ◽

Author(s):

Ahmad Zulfan Hendri ◽

Danarto HR

Keyword(s):

Prostate Cancer ◽

Serum Level ◽

Cancer Patients ◽

Prostate Specific Antigen ◽

Immunohistochemical Staining ◽

Specific Antigen ◽

P53 Expression ◽

The Mean ◽

The Relationship ◽

Anatomical Pathology

Objective: To know the relationship between p53 expression and prostate specific antigen (PSA) serum level in prostate cancer patients. Material & method: Specimens were studied from patients with pathological diagnosis of prostate cancer in Sardjito Hospital Yogyakarta during 2007 to 2008. The p53 expression was measured by immunohistochemical staining. The stains were done in Department of Anatomical Pathology and examined by a pathologist. The relationship between p53 mutated expression and PSA serum level were analyzed with correlation coefficient (rs). Results: There were 29 patients included in this study. The mean age was 66,34 ± 8,15 (50 - 83) years old. The mean PSA serum level was 165,98 ± 269,208 (1,4 – 1051) ng/ml. The mean number of p53 expression was 111,38 ± 94,30 (16 – 396). There was positive correlation between p53 expression and increasing PSA serum level in the prostate cancer patients (rs + 0,497; p = 0,006). Conclusion: P53 expression was positively correlated with increasing PSA serum level.Keywords: Prostate cancer, p53 expression, PSA serum level.

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