scholarly journals Forensic medical evaluation of an isolated injury of the small bowel mesentery and its vessels (literature review extended with expert case report)

2021 ◽  
Vol 12 (4) ◽  
pp. 101-107
Author(s):  
V. N. Makarova ◽  
I. I. Kuznetsov ◽  
S. S. Bachurin ◽  
I. A. Kolomoets
Keyword(s):  
Blood Flow ◽  
Case Report ◽  
Small Bowel ◽  
Scientific Literature ◽  
Mechanism Of Injury ◽  
Mesenteric Vessel ◽  
Medical Evaluation ◽  
Mesenteric Root ◽  
Life Threatening ◽  
Damaged Vessel

This work summarizes information from the modern scientific literature devoted to the issues of morphology and mechanisms of an isolated mesenteric injury, which is rare in expert practice. Apart from classic forensic medical papers, publications over 2000 – 2020, devoted to abdominal organ injuries, were analyzed. In the search engines PUBMED and eLibrary.ru, a selection of sources was made according to the keywords: “rupture of the mesenteric root of the small intestine,” “diagnostics,” “forensic medical evaluation.” The results of the literature analysis were used in the study of the repeated forensic medical examination materials of a case of rapid death (in 1.5 hours) due to a traumatic rupture of the mesentery of the small bowel and its large vessels. The combined analysis of the expert case report and special scientific literature allows us to devise the following conclusions: 1. A forensic expert must have expert knowledge in the normal anatomy of the abdominal aorta’s unpaired vessels and their accompanying veins location and know about their variable topographic and anatomical features. 2. Life-threatening bleeding from the damaged vessel of the mesentery of the small bowel occurs in a wide time interval after the mechanical damage. 3. The development of life-threatening intra-abdominal bleeding is due to the scope of damage and the rate of blood flow from the damaged vessel. 4. Thorough examination of the area of rupture of the mesenteric vessel and the state of the tissues in the circumference of the rupture allow to establish the mechanism of injury. 5. Ignorance of the mechanism of injury and specifics of the formation of injuries is the cause of expert errors and scientifically unfounded conclusions. 6. There is no reference material on the rate of blood flow from a damaged large vessel.

Small Cell Lung Cancer With Life-Threatening Small Bowel Metastasis: A Case Report

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S1396-S1397
Author(s):  
Aynur Rahman ◽  
Tyler Aasen ◽  
Dhara Chaudhari ◽  
Maria Zayko ◽  
Moka Nagaishwarya
Keyword(s):  
Lung Cancer ◽  
Case Report ◽  
Small Bowel ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Small Bowel Metastasis ◽  
Life Threatening

scholarly journals Small bowel trans-vaginal evisceration following vault biopsy: general surgeons beware!

2010 ◽  
Vol 92 (7) ◽  
pp. e6-e7 ◽  
Author(s):  
RJ Codd ◽  
B Scourfield ◽  
S Chakravarthy ◽  
GL Williams
Keyword(s):  
Case Report ◽  
Small Bowel ◽  
Surgical Technique ◽  
Vaginal Evisceration ◽  
Acute Presentation ◽  
Life Threatening ◽  
General Surgeons ◽  
Life Threatening Complication

A case-report of vaginal evisceration following vault biopsy is described. This case highlights the importance of good surgical technique when performing a vaginal biopsy in order to avoid this rare, but life-threatening, complication. General surgeons may well be faced with this acute presentation and prompt management is vital in order to preserve the involved small bowel.

scholarly journals Primary ileal volvulus: a rare twist in an elderly patient—case report

BMC Surgery ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Srikant Agrawal ◽  
Ashwini Ranjan Yadav ◽  
Bikash Nepal ◽  
Pramod Kumar Upadhyay
Keyword(s):  
Case Report ◽  
Small Bowel ◽  
Small Bowel Obstruction ◽  
Bowel Obstruction ◽  
Abdominal Distension ◽  
Exploratory Laparotomy ◽  
Predisposing Factors ◽  
Threatening Condition ◽  
Life Threatening ◽  
History Of

Abstract Background Small bowel volvulus is a rare entity and it is even rarer for the ileum to undergo torsion without any known predisposing factors. It presents as acute abdomen with features of intestinal obstruction. As it is a life-threatening condition, it should be kept as a differential for small bowel obstruction despite its rarity. Therefore, we report this case. Case report A 60-year-old gentleman presented to our emergency department with a 2-day history of worsening abdominal pain, vomiting, abdominal distension and obstipation. Exploratory laparotomy was done which revealed ileal volvulus with no predisposing factors. Derotation of the segment was done. The postoperative period was uneventful and on follow up after a month, he had a satisfying recovery. Conclusion Though primary ileal volvulus is a rare diagnosis, it should be kept in mind in any patient with small bowel obstruction with pain out of proportion and resistant to opioid management. Early diagnosis and urgent surgical intervention is the key to prevent bowel necrosis and associated morbidity and mortality.

scholarly journals A life–threatening small bowel obstruction as onset of an unknown sarcoidosis: A case report

2021 ◽  
Vol 33 ◽  
pp. 101379
Author(s):  
Gregorino Paone ◽  
Alessia Steffanina ◽  
Giulia De Rose ◽  
Giacomo Leonardo ◽  
Daniele Colombo ◽  
...  
Keyword(s):  
Case Report ◽  
Small Bowel ◽  
Small Bowel Obstruction ◽  
Bowel Obstruction ◽  
Life Threatening

Small Bowel Metastasis from Squamous Cell Carcinoma of the Larynx. A Case Report

1993 ◽  
Vol 79 (4) ◽  
pp. 286-287 ◽  
Author(s):  
Mario Airoldi ◽  
Pietro Gabriele ◽  
Giovanni Succo ◽  
Guido Valente ◽  
Vincenzo Brando
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Small Bowel ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Small Bowel Metastases ◽  
Small Bowel Metastasis ◽  
Carcinoma Of The Larynx ◽  
Life Threatening ◽  
Life Threatening Complication

Small bowel metastases from squamous cell carcinoma of the head and neck are relatively rare and in some cases asymptomatic. In the case herein reported, small bowel metastasis from a laryngeal carcinoma caused a life-threatening complication. The surgical approach was effective in saving the patient's life. Death occurred for neck tumor progression without abdominal signs of secondary lesions. A review of the previously reported cases is provided.

scholarly journals Small Bowel Obstruction due to Meckel’s Diverticulum: A Case Report

2018 ◽  
Vol 3 (1) ◽  
pp. 32
Author(s):  
Mania Beiranvand ◽  
Morteza Mohammadirokh ◽  
Babak Khodadadi
Keyword(s):  
Case Report ◽  
Small Bowel ◽  
Small Bowel Obstruction ◽  
Operating Room ◽  
Bowel Obstruction ◽  
Meckel’S Diverticulum ◽  
Meckel's Diverticulum ◽  
Meckel Diverticulum ◽  
Mesenteric Root ◽  
Surgical Methods

Background: Meckel Diverticulum is the most common congenital gastrointestinal malformation, which is 40% of cases have symptoms of intestinal obstruction. The prevalence of this disorder is between 1% and 4% of the population and the possibility of its occurring in men is twice that women. Most of Meckel diverticulums are asymptomatic so it is difficult to diagnose properly the Meckel diverticulum before surgery it may not be detectable because of other intra-abdominal complications such as appendicitis, inflammatory bowel disease, or other causes of small bowel obstruction,Case Report: The patient was a 28-year-old man who had abdominal pain with repeated vomiting two days earlier. In abdominal and pelvic CT scans, the dilatation of small bowel loops with screw loops around the arterial origin and upper mesenteric vein and the mesenteric root has been reported. Due to the lack of clinical improvement, the patient was transferred to the operating room for laparotomy. In the operating room, a large adhesive band of about 60 cm of the ileocecal valve was released, and the broad and inflamed diverticulitis was removed at a base of about 2 to 2.5 cm.Conclusion: Detecting Meckel’s diverticulum with no sign from normal colon using a CT scan is difficult, but laparoscopy as a useful tool in the diagnosis of Meckel’s diverticulum has been reported. The care standard of Meckel’s diverticulum is a surgical procedure for the removal of complications. Surgical methods used include simple diverticulectomy or removing part of the ileum that diverticulum is located. For proper diagnosis especially in patients with unusual symptoms, It is necessary that the symptoms of diverticulum are consideredInternational Journal of Human and Health Sciences Vol. 03 No. 01 January’19. Page : 32-36

Presentation of Gall Stone Ileus as Gut Obstruction

JMS SKIMS ◽  
2019 ◽  
Vol 21 (2) ◽  
pp. 117-119
Author(s):  
Munir Ahmad Wani ◽  
Mubarak Ahmad Shan ◽  
Syed Muzamil Andrabi ◽  
Ajaz Ahmad Malik
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Ct Scan ◽  
Bowel Obstruction ◽  
Emergency Surgery ◽  
Gallstone Ileus ◽  
Gall Stone ◽  
Life Threatening ◽  
Life Threatening Complication ◽  
Gall Stone Ileus

Gallstone ileus is an uncommon and often life-threatening complication of cholelithiasis. In this case report, we discuss a difficult diagnostic case of gallstone ileus presenting as small gut obstruction with ischemia. A 56-year-old female presented with abdominal pain and vomiting. A CT scan was performed and showed an evolving bowel obstruction with features of gut ischemia with pneumobilia although no frank hyper density suggestive of a gallstone was noted. The patient underwent emergency surgery and a 60 mm obstructing calculus was removed from the patient's jejunum, with a formal tube cholecystostomy. JMS 2018: 21 (2):117-119

Alteraciones sistémicas y metabólicas producidas por lesión medular

2019 ◽  
Vol 1 (1) ◽  
pp. 59-75
Author(s):  
Gabriel Guízar Sahagún
Keyword(s):  
Spinal Cord ◽  
Daily Living ◽  
Autonomic Function ◽  
Clinical Presentation ◽  
Scientific Literature ◽  
International Standards ◽  
Therapeutic Approaches ◽  
Cord Injury ◽  
Life Threatening ◽  
The Impact

Besides the well-known loss of motor and sensory capabilities, people with spinal cord injury (SCI) experience a broad range of systemic and metabolic abnormalities including, among others, dysfunction of cardiovascular, respiratory, gastrointestinal, urinary, and endocrine systems. These alterations are a significant challenge for patients with SCI because such disorders severely interfere with their daily living and can be potentially life-threatening. Most of these disorders are associated with impairment of regulation of the autonomic nervous system, arising from disruption of connections between higher brain centers and the spinal cord caudal to the injured zone. Thus, the higher and more complete the lesion, the greater the autonomic dysfunction and the severity of complications.This article summarizes the medical scientific literature on key systemic and metabolic alterations derived of SCI. It provides information primarily focused on the pathophysiology and clinical presentation of these disorders, as well as some guides to prevent and alleviate such complications. Due to the impact of these alterations, this topic must be a priority and diffuse to those involved with the care of people with SCI, including the patient himself/herself. We consider that any collaborative effort should be supported, like the development of international standards, to evaluate autonomic function after SCI, as well as the development of novel therapeutic approaches.

scholarly journals Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Gautier Follain ◽  
Naël Osmani ◽  
Valentin Gensbittel ◽  
Nandini Asokan ◽  
Annabel Larnicol ◽  
...  
Keyword(s):  
Blood Flow ◽  
Tumor Cells ◽  
Molecular Mechanisms ◽  
Metastatic Progression ◽  
Metastatic Dissemination ◽  
Secondary Tumors ◽  
Flow Profiles ◽  
Endothelial Response ◽  
Life Threatening

AbstractTumor progression and metastatic dissemination are driven by cell-intrinsic and biomechanical cues that favor the growth of life-threatening secondary tumors. We recently identified pro-metastatic vascular regions with blood flow profiles that are permissive for the arrest of circulating tumor cells. We have further established that such flow profiles also control endothelial remodeling, which favors extravasation of arrested CTCs. Yet, how shear forces control endothelial remodeling is unknown. In the present work, we aimed at dissecting the cellular and molecular mechanisms driving blood flow-dependent endothelial remodeling. Transcriptomic analysis of endothelial cells revealed that blood flow enhanced VEGFR signaling, among others. Using a combination of in vitro microfluidics and intravital imaging in zebrafish embryos, we now demonstrate that the early flow-driven endothelial response can be prevented upon specific inhibition of VEGFR tyrosine kinase and subsequent signaling. Inhibitory targeting of VEGFRs reduced endothelial remodeling and subsequent metastatic extravasation. These results confirm the importance of VEGFR-dependent endothelial remodeling as a driving force of CTC extravasation and metastatic dissemination. Furthermore, the present work suggests that therapies targeting endothelial remodeling might be a relevant clinical strategy in order to impede metastatic progression.

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