Clinical characteristics and epidemiology survey of lung transplantation recipients accepting surgeries during COVID-19 pandemic：from area near Hubei Province (Preprint)

2020 ◽  
Author(s):  
Lingxiao Qiu ◽  
Shanshan Chen ◽  
Cong Wang ◽  
Caihong Liu ◽  
Huaqi Wang ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Clinical Characteristics ◽  
Lung Transplant ◽  
The Novel ◽  
Web Based ◽  
Transplant Program ◽  
Medical Institutions ◽  
Survey Results ◽  
Wbc Count ◽  
Novel Coronavirus

BACKGROUND Lung transplantation recipients (LTx) are more susceptible to severe acute respiratory syndrome-corona virus-2 (SARS-Cov-2) and suffer severer outcomes than healthy subjects. OBJECTIVE Here we aim to analyze whether it was appropriate to maintain lung transplant programs in medical institutions accepting coronavirus disease 2019 (COVID-19) patients. METHODS Methods: the clinical characteristics, laboratory testing, and epidemiology survey results of 10 LTx recipients undergoing allograft lung transplantation surgeries in the First Affiliated Hospital of Zhengzhou University during the COVID-19 pandemic were collected. A web-based epidemiology questionnaire was used to collect the information of LTx recipients after discharge. RESULTS A total of 10 LTx recipients were identified. The main cause of lung transplantation was idiopathic interstitial pneumonia (60%), with another rare case of cystic fibrosis. Comorbidities involved hyperlipidemia, subclinical hyperthyroidism, diabetes, viral hepatitis of type B. The average white blood cell (WBC) count and average lymphocyte count were 9.5±3.9×109 cells/liter and 1.7±1.1×109 cells/liter, respectively. 40% of the LTx recipients had lymphopenia. Impaired alanine aminotransferase (ALT) and aspartate transaminase (AST) were observed in LTx recipients. Good habitats of hand hygiene (100%), wearing protective masks behaviors (100%), indoor ventilation behaviors (100%), indoor disinfection measures (83%), personal tableware (67%), separate room (100%), personal bedsheets/ quilts (100%) and drinking glasses (100%) were observed during the follow-up. None of the LTx recipients or their family members get infected with SARS-CoV-2 during the novel coronavirus pandemic. CONCLUSIONS Under the premise of taking appropriate preventive measures during hospitalization and after discharge, the lung transplant program can be maintained in the medical institution that accepts patients with COVID-19. INTERNATIONAL REGISTERED REPORT RR2-doi: https://doi.org/10.1101/2020.07.06.20147264

scholarly journals Clinical characteristics and epidemiology survey of lung transplantation recipients accepting surgeries during the COVID-19 pandemic : from area near Hubei Province

2020 ◽  
Author(s):  
Lingxiao Qiu ◽  
Shan shan Chen ◽  
Cong Wang ◽  
Caihong Liu ◽  
Huaqi Wang ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Clinical Characteristics ◽  
Lung Transplant ◽  
Preventive Measures ◽  
The Novel ◽  
Web Based ◽  
Transplant Program ◽  
Medical Institutions ◽  
Survey Results ◽  
Novel Coronavirus

AbstractLung transplantation recipients (LTx) were susceptible to severe acute respiratory syndrome-corona virus-2 (SARS-Cov-2) and suffered a higher mortality risk than healthy subjects. Here we aim to analyze whether it was appropriate or and valuable to maintain lung transplant programs in medical institutions accepting coronavirus disease 2019 (COVID-19) patients. In this study, the clinical characteristics, laboratory testing and epidemiology survey results of 10 LTx recipients undergoing allograft lung transplantation surgeries in the First Affiliated Hospital of Zhengzhou University during the COVID-19 pandemic were collected. A web-based epidemiology questionnaire was used to collect the information of LTx recipients after discharge. Up to now, none of the LTx recipients or their family members get infected with SARS-CoV-2 during the novel coronavirus pandemic. In conclusion, under the premise of taking appropriate preventive measures during hospitalization and after discharge, the lung transplant program can be maintained in the medical institution that accepts patients with COVID-19.

Survey on the dissemination of Web-based information on “evacuation and sheltering” in the context of COVID-19 by the Japanese Government

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Hiroaki Sano ◽  
Yohei Chiba ◽  
Sachiko Maeda ◽  
Chiharu Ikeda ◽  
Nobuyuki Handa ◽  
...  
Keyword(s):  
Design Methodology ◽  
Information Dissemination ◽  
Central Government ◽  
Health Centers ◽  
The Novel ◽  
Web Based ◽  
Content Type ◽  
Administrative Agencies ◽  
Novel Coronavirus ◽  
Actual Response

Purpose This study examines the websites of central government ministries, prefectures and municipalities to obtain a comprehensive bird’s-eye view of how they are preparing for natural disasters in the context of the novel coronavirus (COVID-19) outbreak. Design/methodology/approach This study examines the websites of central government ministries, prefectures and municipalities in Japan to survey the actual status of information dissemination on “evacuation and sheltering” in the context of COVID-19. Findings This study found that the central government issued many notices, notifications and administrative communications to prefectures, cities with public health centers and special wards, which were mainly related to opening, securing and operating evacuation centers and improving the environment. It was found that most prefectures disseminated information on both survival and living evacuation and did so from June onward, when the flood season was approaching. Among the municipalities, there were differences in information dissemination tendencies by prefecture, and it became clear that smaller municipalities were especially incapable of fully disseminating information via the Web. Research limitations/implications The data from the prefectures and municipalities surveyed in this study were collected from websites and do not necessarily represent the actual response to disaster-related evacuation in the context of COVID-19 in those areas. To clarify this evacuation, more detailed surveys are needed. Originality/value This study is unique because no research has been conducted on the response of Japanese administrative agencies to disaster-related evacuation in the context of COVID-19; the actual situation was analyzed in this study by examining central government ministries, prefectures and municipalities as administrative agencies and comparing their responses.

scholarly journals How to Dispose of Medical Waste Caused by COVID-19? A Case Study of China

2021 ◽  
Vol 18 (22) ◽  
pp. 12127
Author(s):  
Min Su ◽  
Qiang Wang ◽  
Rongrong Li
Keyword(s):  
Waste Disposal ◽  
Medical Waste ◽  
Chinese Government ◽  
The Novel ◽  
Global Epidemic ◽  
Medical Institutions ◽  
Process System ◽  
The Government ◽  
Novel Coronavirus ◽  
And Control

The rapid increase in novel coronavirus (COVID-19) patients also means a rapid increase in medical waste that could carry the novel coronavirus (SARS-CoV-2). How to safely dispose of medical waste caused by COVID-19 is a huge challenge that needs to be solved urgently. The outbreak of the COVID-19 has led to a significant increase in the daily generation of medical waste in China and has placed a severe test on the Chinese medical waste disposal system. Unlike ordinary wastes and garbage, medical waste that is untreated or incompletely treated will not only cause environmental pollution, but also directly or indirectly cause infections and endanger people’s health. Faced with difficulties, the Chinese government formulated a policy for medical waste management and a response plan for the epidemic, which provides policy guarantee for the standardized disposal of epidemic medical waste. In addition, the government and medical institutions at all levels formed a comprehensive, refined, and standardized medical treatment process system during research and practice. China has increased the capacity of medical waste disposal in various places by constructing new centralized disposal centers and adding mobile disposal facilities. China has achieved good results in the fight against COVID-19, and the pressure on medical waste disposal has been relieved to a certain extent. However, the global epidemic situation is severe. How to ensure the proper and safe disposal of medical waste is related to the prevention and control of the epidemic situation. This study summarizes China’s experience in the disposal of medical waste in the special case of COVID-19 and hopes to provide some reference for other countries in the disposal of medical waste.

scholarly journals Student-Designed Cross-Sectional Pandemic Knowledge Survey of 8th−12th Grade Students, Milwaukee, WI, April 2020

2021 ◽  
Vol 9 ◽  
Author(s):  
Krish Vasudev ◽  
Hersh Singh ◽  
August A. Neumann ◽  
William M Zhao ◽  
Lyle Dominic Pelayo Mondano
Keyword(s):  
The Novel ◽  
Cross Sectional ◽  
Safety Measures ◽  
Web Based ◽  
12Th Grade ◽  
Twelfth Grade ◽  
Level Of Understanding ◽  
Novel Coronavirus ◽  
High Level ◽  
Knowledge Survey

Background: The novel coronavirus and its effect on our society are unprecedented. Given the recent pandemic, numerous measures have been taken to protect our communities. We sought to understand our school community's knowledge and the measures that were taken by our school for our safety.Objective: Our objective was to describe the overall understanding and attitudes of 8–12th grade students from a single institution during the initial phase of the Wisconsin's Governor's stay-at-home order.Methods: A voluntary web-based survey was communicated to 8–12th grade students through their online school portal. Data were collected and analyzed using SurveyMonkey.Results: There was a 20.2% response rate. Answers regarding the coronavirus, spread, and response to the coronavirus pandemic showed a high level of understanding of the virus and the actions necessary to prevent its spread.Conclusion: Eight-twelfth grade students have a high level of understanding of the virus, its effects, and the safety measures implemented to protect society.

scholarly journals A Survey-based Study of Psychological Impact of Lock Down Due to COVID 19 Pandemic on Indian Working Class Using Statistical Design

2021 ◽  
Vol 11 (4) ◽  
pp. 4531-4544
Author(s):  
Sambit Prasad Kar ◽  
Nirmal Kumar Rout ◽  
Jonathan Joshi
Keyword(s):  
Working Class ◽  
Psychological Impact ◽  
Statistical Design ◽  
The Novel ◽  
Confined Space ◽  
Cross Sectional ◽  
Web Based ◽  
Adequate Knowledge ◽  
Level Of Knowledge ◽  
Novel Coronavirus

The novel coronavirus (COVID-19), identified within the Wuhan, Hubei Province of China in November 2019, needs distinct attention because of its fatal nature. The spreading of any infectious diseases is generally prevented by quarantine and containment or locking down of the populations in danger. Countries suffering from COVID-19 are declaring the country lockdown and restricting public movement. India also has declared full lockdown and restricted public movement to a large extent. Such drastic steps have a severe psychological impact on populations. Being locked up for weeks in a very confined space with the same group of individuals being depressed, nervous, and tired, which is further aggravating various domestic and interpersonal issues. A web-based survey was formed which supported a cross-sectional sampling method and collected data across different working-class population groups in India. The responders had a beginner level of knowledge about the COVID-19 infection and adequate knowledge about its preventive aspects was unknown. Results indicate that 13% of the respondents experienced severe anxiety, 11% moderate anxiety, and 28% are mildly anxious. The results suggest that governments should find effective ways to disseminate unbiased COVID-19 knowledge to reduce population insecurity and provide the best mental equipment to cope with the pandemic.

scholarly journals Associations of clinical characteristics and antiviral drugs with viral RNA clearance in patients with COVID-19 in Guangzhou, China: a retrospective cohort study

2020 ◽  
Author(s):  
Xudan Chen ◽  
Yuying Zhang ◽  
Baoyi Zhu ◽  
Jianwen Zeng ◽  
Wenxin Hong ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Time Lag ◽  
Treatment Strategies ◽  
Antiviral Drugs ◽  
Viral Rna ◽  
The Novel ◽  
Illness Onset ◽  
Treatment Regimens ◽  
Global Pandemic ◽  
Novel Coronavirus

AbstractBackgroundThe novel coronavirus disease 2019 (COVID-19) characterized by respiratory symptoms has become a global pandemic although factors influencing viral RNA clearance remained unclear to inform optimal isolation period and treatment strategies.MethodsIn this retrospective study, we included patients with confirmed COVID-19 admitted to Guangzhou Eighth People’s Hospital from 20th January 2020 to 15th March 2020. The associations of clinical characteristics and treatment regimens on time to viral RNA clearance were analyzed.ResultsWe examined 284 consecutive COVID-19 cases, accounting for 82% of confirmed cases in Guangzhou during this period. At the time of reporting (20th March 2020), 276 (97.2%) had recovered and were discharged from hospital with a median hospital stay of 18 days (interquartile range [IQR]:13-24). Overall, 280 patients achieved viral RNA clearance with a median length of 12 days (IQR: 8-16) after onset of illness. Amongst them, 66.1% had viral RNA cleared within 14 days, and 89.3% within 21 days. Older age, severity of disease, time lag from illness onset to hospital admission, high body temperature, and corticosteroid use were associated with delayed clearance of viral RNA. None of the antiviral regimens (chloroquine, oseltamivir, arbidol, and lopinavir/ritonavir) improved viral RNA clearance. The use of lopinavir/ritonavir was associated with delayed clearance of viral RNA after adjusting for confounders.ConclusionIn patients with COVID-19, isolation for a minimum of 21 days after onset of illness may be warranted, while the use of antiviral drugs does not enhance viral RNA clearance.Brief SummaryViral RNA was cleared in 89% of the COVID-19 patients within 21 days after illness onset. The use of antiviral drugs (chloroquine, oseltamivir, arbidol, and lopinavir/ritonavir) did not shorten viral RNA clearance, especially in non-serious cases.

scholarly journals A study on the clinical characteristics and management of patients with mild cases of COVID-19 in shelter hospitals from China

2020 ◽  
Author(s):  
Tao FENG ◽  
Canhua YANG ◽  
Guiying LI ◽  
Daoye LIANG ◽  
Xinju JIA ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Nasal Congestion ◽  
Screening Method ◽  
Runny Nose ◽  
Blood Biochemical ◽  
Clinical Type ◽  
Clinical Presentations ◽  
Significant Difference ◽  
Wbc Count ◽  
Novel Coronavirus

Abstract Background: To review the clinical characteristics of patients with mild cases of novel coronavirus disease (COVID-19) pneumonia admitted to shelter hospitals and to investigate the management patterns of shelter hospitals. Methods: We collected and analyzed the case data of 931 patients of their general conditions, main clinical presentations, outcomes, laboratory results, imaging. Results: The average age of patients with mild cases of COVID-19 was （46.68 ± 12.13） years. There was no significant difference in incidence between males and females. The most common clinical presentations were fever (60.79%), cough (47.37%), myalgia and fatigue (17.40%), sore throat (13.86%), sputum (13.86%), diarrhea (9.98%), chest distress and dyspnea (8.38%), nasal congestion (6.02%), and runny nose (5.69%), while 10.10% were asymptomatic. In addition, anxiety and insomnia were present in 12.13% of cases. COVID-19 clinical type: mild, 248 cases (26.64%); moderate, 683 cases (73.36%). Blood biochemical examination showed that some patients exhibited WBC count (26.32%) lower to normal. Most patients tested positive for novel coronavirus nucleic acid (55.45%), while 44.55% tested negative. The rate of positive chest computed tomography (CT )examination findings was 94.36%. The most common change were ground-glass opacities (48.70%) and multiple patchy opacities (44.58%). Moreover, 65 patients (6.98%) were transferred to designated hospital, primarily due to exacerbation of novel coronavirus pneumonia (32 cases, 49.2%). Conclusions: COVID-19 patients in shelter hospitals were in a relatively mild overall condition and were predominantly of the moderate clinical type. Attention should be paid to asymptomatic positive patients and patients without respiratory symptoms. CT is still the main patient screening method. Shelter hospitals can carry the burden of epidemic prevention and treatment of patients with mild cases of COVID-19.

scholarly journals Online Delivery of Teaching and Laboratory Practices: Continuity of University Programmes during COVID-19 Pandemic

2020 ◽  
Vol 10 (10) ◽  
pp. 291
Author(s):  
Kelum A. A. Gamage ◽  
Dilani I. Wijesuriya ◽  
Sakunthala Y. Ekanayake ◽  
Allan E. W. Rennie ◽  
Chris G. Lambert ◽  
...  
Keyword(s):  
Learning Experience ◽  
Mode Of Delivery ◽  
National Policy ◽  
Academic Standards ◽  
The Novel ◽  
Web Based ◽  
Online Delivery ◽  
Face To Face ◽  
Laboratory Facilities ◽  
Novel Coronavirus

A great number of universities worldwide are having their education interrupted, partially or fully, by the spread of the novel coronavirus (COVID-19). Consequently, an increasing number of universities have taken the steps necessary to transform their teaching, including laboratory workshops into an online or blended mode of delivery. Irrespective of the measures taken, universities must continue to maintain their high academic standards and provide a high-quality student experience as required for delivery of learning outcomes associated with each degree programme. This has created a challenge across the higher education landscape, where academics had to switch to remote teaching and different approaches to achieving laboratory delivery. As a result, students have not been receiving face-to-face teaching, and access to laboratory facilities has been limited or nearly impossible. This paper reviews numerous approaches taken by universities to deliver teaching and laboratory practices remotely, in consideration of the COVID-19 pandemic, whilst also considering the potential impacts on the student learning experience. This review is primarily focused on the fields of engineering, science and technology, based on published literature including books, reviewing web-based provision of selected universities, institutional and national policy documents.

Clinical characteristics of skin manifestations with the novel coronavirus infection COVID-19 caused by SARS-CoV-2

2020 ◽  
Vol 19 (3) ◽  
pp. 271
Author(s):  
N.N. Potekaev ◽  
O.V. Zhukova ◽  
D.N. Protsenko ◽  
G.M. Kozhevnikova ◽  
O.M. Demina ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
The Novel ◽  
Skin Manifestations ◽  
Coronavirus Infection ◽  
Novel Coronavirus

scholarly journals Implantable System for Treprostinil and Lung Transplantation: Case Series from Delivery for Pulmonary Arterial Hypertension Study

2021 ◽  
pp. 204589402199929
Author(s):  
Jeremy Feldman ◽  
Mardi Gomberg-Maitland ◽  
Shelly M Shapiro ◽  
Amy Lautenbach ◽  
Marty Morris ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Lung Transplantation ◽  
Lung Transplant ◽  
Case Series ◽  
Patient Characteristics ◽  
Effective Strategies ◽  
Transplant Program ◽  
Pulmonary Arterial ◽  
Bilateral Lung

Background The implanted system for treprostinil (IST) has been described in previous publications. There is no information published about how to handle this system around lung or heart lung transplantation. We present the experience from the DelIVery for Pulmonary Arterial Hypertension (PAH) study. Methods Of the 60 subjects enrolled in the DelIVery study, seven subjects from five pulmonary arterial hypertension (PAH) centers had been listed for bilateral lung or heart and lung transplant, and were included in this analysis. All subjects were participating in the previously described DelIVery for PAH study. 1,2 Results Seven subjects with implanted pumps have been listed for lung or heart-lung transplant. Six subjects underwent lung or heart lung transplantation and one remains on the transplant list. Three different methods of patient management for transplant were used. In three subjects the implanted system was filled with saline prior to transplantation and treprostinil was infused via an external system. Three subjects had their drug-filled implanted pump and catheter system explanted at the time of transplant. One patient had the drug-filled implanted system removed prior to being listed for transplantation. Four subjects were hospitalized while waiting for transplantation. Conclusion The eight year experience from the DelIVery for PAH study confirms that the IST is not a barrier to safe lung or heart lung transplantation. The experience described here provides three effective strategies for managing the implanted system around lung or heart lung transplantation. The optimal strategy will depend on patient characteristics and lung transplant program preferences and wait list times.

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