Virtual Prehabilitation of Surgical Cancer Patients in Times of the Covid-19 Pandemic: A Feasibility Study (Preprint)

2021 ◽  
Author(s):  
Genevieve Lambert ◽  
Kenneth Drummond ◽  
Bhagya Tahasildar ◽  
Francesco Carli

BACKGROUND Since the beginning of the Covid-19 Pandemic, preoperative care, also termed prehabilitation, have become increasingly relevant due to the decreasing functional and psychosocial health of cancer patients due to the restrictions. Concurrently, there has been improved access to telehealth, which defines all remote care delivery facilitated by information technologies (i.e., virtually). This present protocol describes the rationale and methodology for a major trial investigating the feasibility and primary effectiveness of multimodal virtual prehabilitation services (i.e, teleprehabilitation). OBJECTIVE This present protocol describes the rationale and methodology for a major trial investigating the feasibility and primary effectiveness of multimodal virtual prehabilitation services (i.e, teleprehabilitation). METHODS This quality improvement trial aims to recruit 100 cancer patients to receive teleprehabilitation throughout their preoperative period. The inclusion criteria are: (1) 18 years old, scheduled for elective cancer surgery and referred by a surgeon, (2) to be medically cleared by the referring physician to engage in physical activity; and (3) to have a good comprehension of the English or French language. RESULTS Feasibility will be assessed by documenting adherence and completion rate, in addition to process challenges and benefits, and reasons for not participating in the trial or for discontinuation. Secondary outcomes will be preoperative and postoperative functional capacity and clinical outcomes, in addition to health-related quality of life, anxiety and depression, upon recruitment, before the surgery, and four- and height-week after the surgery. CONCLUSIONS This trial will provide guidance on the use of telehealth in the administration of prehabilitation services, providing large scale information responding to gaps of the literature, as there are minimal reports on the use of telehealth rehabilitation/ prehabilitation services with the elderly populations and in acute contexts, such as the preoperative period. CLINICALTRIAL ClinicalTrials.gov, NCT0479956, registered prospectively on March 16th, 2021; https://clinicaltrials.gov/ct2/show/NCT04799561

Author(s):  
Hester.R. Trompetter ◽  
Cynthia S. Bonhof ◽  
Lonneke V. van de Poll-Franse ◽  
Gerard Vreugdenhil ◽  
Floortje Mols

Abstract Purpose Chemotherapy-induced peripheral neuropathy ((CI)PN) becomes chronic in 30% of cancer patients. Knowledge of predictors of chronic (CI)PN and related impairments in health-related quality of life (HRQoL) is lacking. We examined the role of optimism in chronic (CI)PN severity and associated HRQoL in colorectal cancer (CRC) patients up to two years after diagnosis. Methods CRC patients from a prospective cohort study participated, with sensory peripheral neuropathy (SPN) 1 year after diagnosis (n = 142). Multivariable regression analyses examined the cross-sectional association between optimism (measured by the LOT-R) and SPN severity/HRQoL (measured by the EORTC QLQ-CIPN20 and QLQ-C30), as well as the prospective association in a subsample that completed measures 2 years after diagnosis and still experienced SPN (n = 86). Results At 1-year follow-up, higher optimism was associated with better global HRQoL, and better physical, role, emotional, cognitive, and social functioning (all p < .01). Optimism at year one was also prospectively associated with better global HRQoL (p < .05), and emotional and cognitive functioning at 2-year follow-up (both p < .01). Optimism was not related to self-reported SPN severity. Significant associations were retained when controlling for demographic/clinical variables, and became non-significant after controlling for depressive and anxiety symptoms. Conclusions Optimism and depressive and anxiety symptoms are associated with HRQoL in CRC patients with chronic (CI)PN. Future research may illuminate the mechanisms that these factors share, like the use of (non)adaptive coping styles such as avoidance and acceptance that may inform the design of targeted interventions to help patients to adapt to chronic (CI)PN.


Author(s):  
Jiyoung Song ◽  
Eunwon Lee

This study aimed to describe the health-related quality of life of elderly women with experience in fall treatment as well as to prepare basic data for the development of interventions to improve the quality of life for this group. The study was based on raw data from the 2019 Korea Community Health Survey. Using the SPSS program, the characteristics of the subjects were tested by frequency, percentage, and chi-square test. To establish the impact of fall experience on the health-related quality of life of elderly women, the OR and 95% CI were calculated using multiple logistic regression analysis. Of the 4260 people surveyed, 44.7% of the elderly women said they had a high quality of life, whereas 55.3% of the elderly women said they had a low quality of life. A younger age was associated with a better-rated health-related quality of life. Those who lived in a city and had a high level of education tended to describe a high quality of life. The quality of life was considered high by those who exercised, but low by those who were obese or diabetic. The results of this study can lead to a better understanding of the experiences of elderly women who have experienced falls, and they can be used as basic data for the development of related health programs.


2006 ◽  
Vol 16 (2) ◽  
pp. 157-164 ◽  
Author(s):  
Annette Majnemer ◽  
Catherine Limperopoulos ◽  
Michael Shevell ◽  
Charles Rohlicek ◽  
Bernard Rosenblatt ◽  
...  

Infants who survive open-heart surgery are at risk for developmental disability, which may impact on the well-being not only of the child, but also the family. The objective of our prospective study, therefore, was to determine the long-term health-related quality of life of children with congenital cardiac malformations following open-heart surgery, and to describe the persisting level of stress in their families. To this end, 49 parents completed the Child Health Questionnaire, the Parenting Stress Index, and the Child Behaviour Checklist as part of a developmental follow-up protocol when their child was 5 years of age. Mean scores on the Child Health Questionnaire were in the normal range, with physical well-being equal to 53.5, psychosocial well-being 50.9, with only 6.4 percent and 8.5 percent of subjects, respectively, falling within the suboptimal range of less than 40. The distribution of scores on the Parenting Stress Index, however, were more variable, with over one-quarter of parents indicating a high level of stress, with almost one-fifth having low levels of stress, and just over half scoring in the normal range, with the group mean being 52.6 plus or minus 32.3. An abnormal neurologic examination before surgery was associated with lower physical health (β equal to −5.5, p equal to 0.02, r2equal to 0.18), whereas lower arterial saturations of oxygen, less than 85 percent preoperatively, was associated with lower psychosocial health (β equal to −6.6, p equal to 0.01, and r2equal to 0.14). The internalizing and externalizing behaviours of the child were significantly correlated with psychosocial well being, with r ranging from −0.32 to −0.52, and p less than 0.05. Parental stress also correlated with psychosocial health (r equal to −0.48 and p equal to 0.0009). Overall, the perception by the parents of the health-related quality of life of their child is favourable 5 years following open-heart surgery during infancy. Many parents, nonetheless, continue to feel either stressed or defensive about their child, particularly if their child exhibits behavioural difficulties. Our findings suggest that strategies need to be considered to enhance family well-being in the planning and delivery of health services to this population at high risk.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Kristin Zimmermann ◽  
Hadi Mostafaei ◽  
Axel Heidenreich ◽  
Hans U. Schmelz ◽  
Shahrokh F. Shariat ◽  
...  

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