Xenon-Enhanced Dual-Energy CT Lung Ventilation Imaging: Techniques and Clinical Applications

2014 ◽  
Vol 202 (2) ◽  
pp. 309-317 ◽  
Author(s):  
Xiang Kong ◽  
Hui Xue Sheng ◽  
Guang Ming Lu ◽  
Felix G. Meinel ◽  
Kevin T. Dyer ◽  
...  
2018 ◽  
pp. 47-51
Author(s):  
O. E. Karpov ◽  
O. Yu. Bronov ◽  
V. M. Kitaev ◽  
P. S. Vetshev ◽  
D. A. Pikhuta ◽  
...  

Routine diagnostic methods have limitations in terms of predicting the ventilation function of the lungs before and after surgery. It was decided to investigate the possibilities of dual-energy CT (DECT) using xenon in assessment of lung ventilation function.Objective: to master the methods of examination of patients with pulmonary pathology, evaluate the possibility of justifying the volume of operative intervention and prediction of postoperative lung function based on the hybrid images.Materials and methods. For the study, 12 patients with different pulmonary pathologies were selected (COPD – 5, lung cancer – 4, bronchiectasis – 3). Results. It was found that the use of DECT with xenon reflects the functional state of lung tissue.Conclusions. DECT with xenon have potential for planning surgical intervention and introducing the method into modern protocols of preoperative preparation.


Cancers ◽  
2018 ◽  
Vol 10 (7) ◽  
pp. 222 ◽  
Author(s):  
Varsha Jain ◽  
Abigail Berman

Radiation therapy is a major treatment modality for management of non-small cell lung cancer. Radiation pneumonitis is a dose limiting toxicity of radiotherapy, affecting its therapeutic ratio. This review presents patient and treatment related factors associated with the development of radiation pneumonitis. Research focusing on reducing the incidence of radiation pneumonitis by using information about lung ventilation, imaging-based biomarkers as well as normal tissue complication models is discussed. Recent advances in our understanding of molecular mechanisms underlying lung injury has led to the development of several targeted interventions, which are also explored in this review.


2018 ◽  
Vol 81 (4) ◽  
pp. 2464-2473 ◽  
Author(s):  
L. Mendes Pereira ◽  
T. Wech ◽  
A.M. Weng ◽  
C. Kestler ◽  
S. Veldhoen ◽  
...  

2014 ◽  
Vol 41 (6Part32) ◽  
pp. 557-557
Author(s):  
B Neal ◽  
J Kipritidis ◽  
R Kohno ◽  
S Matsumoto ◽  
T Yamamoto

2015 ◽  
Vol 50 (5) ◽  
pp. 305-308 ◽  
Author(s):  
Andreas H. Mahnken ◽  
Gregor Jost ◽  
Hubertus Pietsch

Radiology ◽  
2012 ◽  
Vol 263 (1) ◽  
pp. 253-259 ◽  
Author(s):  
Anne-Lise Hachulla ◽  
François Pontana ◽  
Lidwine Wemeau-Stervinou ◽  
Suonita Khung ◽  
Jean-Baptiste Faivre ◽  
...  

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