Foreign body reaction to suture material mimicking malignant microcalcifications in the breast.

1994 ◽  
Vol 162 (3) ◽  
pp. 729-729 ◽  
Author(s):  
V L Schiller ◽  
C Bos ◽  
R J Brenner ◽  
R R Turner
Keyword(s):  
Foreign Body ◽  
Foreign Body Reaction ◽  
Suture Material

Polyvinylidene Fluoride as a Suture Material: Evaluation of Comet Tail-Like Infiltrate and Foreign Body Granuloma

2015 ◽  
Vol 55 (1-2) ◽  
pp. 1-11 ◽  
Author(s):  
Andreas Lambertz ◽  
Kai Michael Schröder ◽  
Dominik Stefan Schöb ◽  
Marcel Binnebösel ◽  
Michael Anurov ◽  
...  
Keyword(s):  
Foreign Body ◽  
Polyvinylidene Fluoride ◽  
Foreign Body Reaction ◽  
Suture Material ◽  
Foreign Body Granuloma ◽  
Male Rats ◽  
Comet Tail ◽  
Suture Materials ◽  
Tissue Integration

Background: Biocompatibility and tissue integration of a surgical suture are decisive factors for wound healing and therefore for the success of sutures. The optimal suture material is still under discussion. Polyvinylidene fluoride (PVDF) is described to have superior properties of biocompatibility and is therefore frequently used as a mesh component. Only little information is available about its use as a suture material. The aim of this study was to evaluate the biocompatibility of PVDF as a suture material in comparison to 5 different established sutures in a rat model. Methods: In 30 male rats, a monofilamental PVDF suture (Resopren®) and 5 established control suture materials [polyester (Miralene®), polytetrafluoroethylene (Gore®), poliglecaprone (Monocryl®), polydioxanone (Monoplus®), polyglactin 910 (Vicryl®), USP size 3-0] were placed in the subcutaneous layer of the abdominal wall without knot or tension. After 3, 7 or 21 days, the abdominal walls were explanted for histopathological and immunohistochemical investigation with special regard to the size and quality of foreign body granuloma and the length of the comet tail-like infiltrate (CTI). Results: The PVDF sutures showed the smallest size of foreign body granuloma (60 ± 14 µm) and the smallest CTI length (343 ± 60 µm) of all polymers after 21 days. Only PVDF (Resopren) and polydioxanone (Monoplus) showed a significant collagen I/III ratio increase between days 3 and 21 (p = 0.009 and p = 0.016). The quality of foreign body reaction regarding inflammation, proliferation and fibrotic remodeling was similar between all suture materials. Conclusions: Our data indicate that monofilamental PVDF sutures show a favorable foreign body reaction with small granuloma sizes and CTI length in comparison to established sutures. Its use as a suture material in general surgery could therefore be extended in the future. To reinforce these findings, further clinical studies need to be conducted.

scholarly journals Granuloma Caused by Carbon Deposition in the Dermis

2014 ◽  
Vol 2014 ◽  
pp. 1-2
Author(s):  
Rintaro Shibuya ◽  
Yuichiro Endo ◽  
Akihiro Fujisawa ◽  
Miki Tanioka ◽  
Yoshiki Miyachi
Keyword(s):  
Computed Tomography ◽  
Foreign Body ◽  
Malignant Melanoma ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Foreign Body Reaction ◽  
Carbon Deposition ◽  
Case Reports ◽  
Initial Injury ◽  
Pencil Lead

Pencil core granuloma is characterized by a delayed foreign-body reaction against retained fragments of pencil lead. Previous case reports presented pencil core granuloma resembling malignant melanoma, haemangioma, or soft tissue sarcoma. We present a case of pencil core granuloma arising from the palm 25 years after the initial injury. The patient presented a bluish nodule that had been present over 25 years before. The nodule initially measured 5 mm in diameter. However, five years before presentation, it suddenly enlarged to the size of 30 mm during six months. Computed tomography (CT) of the lesion revealed a linear radiopaque structure of 8 mm long with a mass on its distal end. Surgical resection revealed a bluish muddy mass and pencil lead. Histological examination revealed degenerative tissue with calcification surrounded by massive amounts of black granular material in the middle and lower dermis.

Microvascular patch technique with and without Silastic T-tube bypass

1984 ◽  
Vol 60 (2) ◽  
pp. 287-295 ◽  
Author(s):  
Peter C. Haines ◽  
R. M. Peardon Donaghy
Keyword(s):  
Foreign Body ◽  
Suture Material ◽  
Vascular Occlusion ◽  
Current Data ◽  
Content Type ◽  
Small Vessels ◽  
T Tube ◽  
Patch Closure ◽  
Patch Technique ◽  
Fine Print

✓ Poor patency results in the surgery of small vessels operated on between 1959 to 1964 was demonstrated to be in part due to the long period of occlusion of the operated vessel during surgery and the presence of a foreign body (suture) in the lumen of the vessel postoperatively. New suture techniques and T-tube bypass were introduced at that time. New experimental data have not been extensively sought since that time. To provide further current data regarding the above observations, 110 arterial vessels (60 carotid arteries 1.1 to 1.3 mm in outside diameter (OD) and 50 femoral arteries 0.6 to 0.7 mm OD) were operated on in rats to compare the bypass versus non-bypass and vein patch closure techniques. In 1-mm vessels, patency rates 1 month after surgery were 100% regardless of the use of bypass or type of closure. Improved visualization, better suture material, and improved surgical skill were probably chiefly responsible for this success. The success rate was not as encouraging, however, in vessels of 0.6 mm OD. The following points are brought out: 1) The presence of the bypass causes damage to the intima in 0.6 mm OD vessels and should not be used. Smaller bypasses do not conduct blood well. 2) Bypass is not required in 1-mm vessels as the patency rate is satisfactory and not altered by its use. 3) The major indication for T-tube bypass is in vessels of 1 mm OD and larger, that nourish tissue which would be damaged by vascular occlusion for 20 to 40 minutes. 4) Foreign body (suture) in the lumen is poorly tolerated in 0.6 mm vessels, but can be tolerated more easily in larger vessels. 5) Techniques that limit the amount of suture material in the lumen are indicated in 0.6-mm vessels. 6) After 1 month, suture material has an epithelial covering and if patency has been maintained for that period of time it is likely to remain.

Foreign body reaction after cochlear implantation

2011 ◽  
Vol 75 (11) ◽  
pp. 1455-1458 ◽  
Author(s):  
Hye Jin Lim ◽  
Eun-So Lee ◽  
Hun Yi Park ◽  
Keehyun Park ◽  
Yun-Hoon Choung
Keyword(s):  
Foreign Body ◽  
Cochlear Implantation ◽  
Foreign Body Reaction

The reaction of the soft tissues of the anterior abdominal wall to various suture material

1982 ◽  
Vol 63 (4) ◽  
pp. 72-74
Author(s):  
V. P. Nefedov ◽  
R. M. Ramazanov
Keyword(s):  
Foreign Body ◽  
Abdominal Wall ◽  
Soft Tissues ◽  
Suture Material ◽  
Anterior Abdominal Wall ◽  
The Body ◽  
Reactive Changes ◽  
Healing Processes

The healing processes of sutured wounds of soft tissues in most cases depend on the type and quality of the suture material. Any kind of suture material in the tissues of the body is a foreign body that causes various reactive changes from the tissues. The nature of these changes, all other things being equal, is mainly determined by the type of suture material, its thickness and the method of sterilization of the tissues on which the sutures are applied, the trauma of surgery, the infection of the wound and the irritating effect of the threads on the tissues.

Foreign body reaction of the brain: Enzyme-histochemical study in dogs

Neurology ◽  
1967 ◽  
Vol 17 (4) ◽  
pp. 337-337 ◽  
Author(s):  
T. Yanagihara ◽  
N. P. Goldstein ◽  
H. J. Svien ◽  
R. C. Bahn
Keyword(s):  
Foreign Body ◽  
Foreign Body Reaction ◽  
Histochemical Study ◽  
The Brain
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