Near Identification of Policy Trade-Offs Using Preference Proxies to Elicit Hidden Information in the Linear Case

This paper shows that neither OLS nor 2SLS can generically identify policy trade offs in the linear case, except under extreme assumptions. Practitioners must be content with near identification and the paper discusses how to choose between these two methods. It shows that a two-stage approach using preference proxies to elicit hidden information can potentially narrow the identification gap and that a simple specification test can be used to assess whether these proxies really contribute to improving identification.

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Production trade-offs and weight restrictions in two-stage network data envelopment analysis

International Journal of Applied Decision Sciences ◽

10.1504/ijads.2020.104304 ◽

2020 ◽

Vol 13 (1) ◽

pp. 21

Author(s):

Hamid Kiaei ◽

Reza Kazemi Matin ◽

Seyed Hadi Nasseri

Keyword(s):

Data Envelopment Analysis ◽

Network Data ◽

Data Envelopment ◽

Weight Restrictions ◽

Two Stage ◽

Network Data Envelopment Analysis ◽

Trade Offs

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Optimal coordination strategies for flood control and hydropower generation of reservoir

10.5194/egusphere-egu2020-12554 ◽

2020 ◽

Author(s):

Lin Zhang ◽

Wei Ding ◽

Guoli Wang

Keyword(s):

Water Level ◽

Flood Control ◽

Flood Damage ◽

Hydropower Generation ◽

Two Stage ◽

Forecast Uncertainty ◽

Streamflow Forecast ◽

Trade Offs ◽

Water Head ◽

Optimal Coordination

<p>During flood seasons, the water head of the reservoir is kept in flood limited water level (FLWL) to satisfy the flood control objective, but this runs counter to the need for hydropower generation to maintain a high water-head. This paper focuses on the optimal hedging rules by setting an appropriate FLWL to maximize the benefit of hydropower without increasing the flood damage and raise the water level at the end of flood for non-flood season/future use. Two-stage hydropower functions considering the constraint conditions which include the downstream environmental flow and installed capacity are built. On the basis of studying the marginal utilities of the two-stage hydropower functions, the competitive and collaborative relationships between flood damage and hydropower benefit were analyzed qualitatively. A two-stage reservoir operation model with two objectives that are minimum flood damage and maximum hydropower generation is developed, which considers streamflow forecast uncertainty and acceptable flood risk. The derived OHR from the model can be used to make trade-offs between flood damage and hydropower benefit under different levels of streamflow forecast uncertainty or acceptable risk. Finally, the analysis is applied to the Nierji Reservoir in the north of China. The results indicate that the OHR can increase hydropower generation 1.57x106kw&#183;h and decrease the volume of abandoned water30.04x106m3 average annual.</p>

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Two-stage seamless transition design from open-label single-arm to randomized double-arm clinical trials

Statistical Methods in Medical Research ◽

10.1177/0962280215625681 ◽

2016 ◽

Vol 27 (1) ◽

pp. 158-171 ◽

Cited By ~ 2

Author(s):

Haolun Shi ◽

Guosheng Yin

Keyword(s):

Clinical Trials ◽

Sample Size ◽

Phase Ii ◽

Therapeutic Effects ◽

Operating Characteristics ◽

Phase Ii Trials ◽

Open Label ◽

Two Stage ◽

Trade Offs ◽

Experimental Drug

Conventional phase II clinical trials use either a single- or multi-arm comparison scheme to examine the therapeutic effects of the experimental drug. Both single- and multi-arm evaluations have their own merits; for example, single-arm phase II trials are easy to conduct and often require a smaller sample size, while multiarm trials are randomized and typically lead to a more objective comparison. To bridge the single- and double-arm schemes in one trial, we propose a two-stage design, in which the first stage takes a single-arm comparison of the experimental drug with the standard response rate (no concurrent treatment) and the second stage imposes a two-arm comparison by adding an active control arm. The design is calibrated using a new concept, the detectable treatment difference, to balance the trade-offs between futility termination, power, and sample size. We conduct extensive simulation studies to examine the operating characteristics of the proposed method and provide an illustrative example of our design.

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Trade-offs and Implications of Two-stage Versus One-stage Unconventional Oil and Gas Exploration and Production Investment Strategies: A Case Study of the Barnett Play

Proceedings of the 5th Unconventional Resources Technology Conference ◽

10.15530/urtec-2017-2670915 ◽

2017 ◽

Author(s):

Wonjae Jang ◽

Svetlana Ikonnikova

Keyword(s):

Oil And Gas ◽

Investment Strategies ◽

Stage Versus ◽

Two Stage ◽

Oil And Gas Exploration ◽

One Stage ◽

Trade Offs ◽

Exploration And Production ◽

Unconventional Oil And Gas

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Trade-offs among power consumption and other design parameters of two-stage recycling folded cascode OTA that using embedded cascode current buffer compensation technology

Integration ◽

10.1016/j.vlsi.2019.06.009 ◽

2019 ◽

Vol 68 ◽

pp. 62-70

Author(s):

Boran Wen ◽

Qisheng Zhang ◽

Xiao Zhao ◽

Xiaolong Lv ◽

Yongqing Wang

Keyword(s):

Power Consumption ◽

Design Parameters ◽

Two Stage ◽

Trade Offs ◽

Folded Cascode

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Two-stage self-seeding method for preparation of single crystals of poly(phenylene sulfide)

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100153816 ◽

1989 ◽

Vol 47 ◽

pp. 368-369

Author(s):

Sengshiu Chung ◽

Peggy Cebe

Keyword(s):

Single Crystals ◽

High Performance ◽

Dilute Solution ◽

Two Stage ◽

Annealing Behavior ◽

High Performance Polymers ◽

Seeding Method ◽

Phenylene Sulfide

We are studying the crystallization and annealing behavior of high performance polymers, like poly(p-pheny1ene sulfide) PPS, and poly-(etheretherketone), PEEK. Our purpose is to determine whether PPS, which is similar in many ways to PEEK, undergoes reorganization during annealing. In an effort to address the issue of reorganization, we are studying solution grown single crystals of PPS as model materials.Observation of solution grown PPS crystals has been reported. Even from dilute solution, embrionic spherulites and aggregates were formed. We observe that these morphologies result when solutions containing uncrystallized polymer are cooled. To obtain samples of uniform single crystals, we have used two-stage self seeding and solution replacement techniques.

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Novel players fine-tune plant trade-offs

Essays in Biochemistry ◽

10.1042/bse0580083 ◽

2015 ◽

Vol 58 ◽

pp. 83-100 ◽

Cited By ~ 25

Author(s):

Selena Gimenez-Ibanez ◽

Marta Boter ◽

Roberto Solano

Keyword(s):

Ubiquitin Ligase ◽

Feedback Loop ◽

Molecular Level ◽

26S Proteasome ◽

Signalling Molecules ◽

Transcriptional Reprogramming ◽

Trade Offs ◽

Jaz Proteins ◽

Regulatory Feedback Loop ◽

Fine Tune

Jasmonates (JAs) are essential signalling molecules that co-ordinate the plant response to biotic and abiotic challenges, as well as co-ordinating several developmental processes. Huge progress has been made over the last decade in understanding the components and mechanisms that govern JA perception and signalling. The bioactive form of the hormone, (+)-7-iso-jasmonyl-l-isoleucine (JA-Ile), is perceived by the COI1–JAZ co-receptor complex. JASMONATE ZIM DOMAIN (JAZ) proteins also act as direct repressors of transcriptional activators such as MYC2. In the emerging picture of JA-Ile perception and signalling, COI1 operates as an E3 ubiquitin ligase that upon binding of JA-Ile targets JAZ repressors for degradation by the 26S proteasome, thereby derepressing transcription factors such as MYC2, which in turn activate JA-Ile-dependent transcriptional reprogramming. It is noteworthy that MYCs and different spliced variants of the JAZ proteins are involved in a negative regulatory feedback loop, which suggests a model that rapidly turns the transcriptional JA-Ile responses on and off and thereby avoids a detrimental overactivation of the pathway. This chapter highlights the most recent advances in our understanding of JA-Ile signalling, focusing on the latest repertoire of new targets of JAZ proteins to control different sets of JA-Ile-mediated responses, novel mechanisms of negative regulation of JA-Ile signalling, and hormonal cross-talk at the molecular level that ultimately determines plant adaptability and survival.

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