scholarly journals D.I.Y. Treatment of Cancer

2020 ◽  
Vol 3 (2) ◽  
pp. p91
Author(s):  
Kenneth J. Hsu

The cancer cells are different from normal human body cells. The scientists advocating the Somatic Mutation Theory speculated that cancer is caused when mutations have caused the Human Genome of the human body-cells to be changed into the Cancer Genomes of the cancer cells. There is, however, no good reason to assume that mutations of the Human Genome would cause the cancer cells to grow and replicate out of control. There is, in fact, no good evidence indicating that there has ever been such mutations, or that cancer cells had been human body cells before they are changed by mutations into cancer cells. Perhaps cancer cells have always been cancer cells, but some cancer cells have not been inherited by the offsprings from their ancestors.Some of us believe that the difference between Human and cancer cells have resulted from the difference of their inherently different genomes, and have not resulted from changes, or mutations. The evolution of the eukaryote genomes and the evolution of the Cancer Genomes during the course of Earth’s history have followed parallel paths of evolution that indicate adaptations of the metabolic modes in response to the ever-increasing oxygenation of the Earth’s atmosphere during the past few billion years. Compared to that of the Human Genome of the human body cells, the cancer cells have genomes that indicate a retarded development in the evolution of the metabolisms. When the Human genome encodes a progressive mode of OXPHOS, the cancer genomes may still encode the anammox mode of metabolism.We cannot deny an assumption that cancer cells have inherited evolving cancer genomes that encode different metabolic modes, while their hallmark is the uncontrolled cell-growth and replications. |We have good evidence that cancer genomes have also evolved to encode progressively different metabolic modes. Chinese medical scientists have found, for example, a wealth of evidence that some forms of cancer may have been caused by the nitrite pollution of the public water supply. China’s Deep Standardized Well Water (DSWW) Program of substituting nitrite-free deep groundwaters as the source of public water supply was partially successful. Local cancer-mortality rates were reduced by half at places where there had been such substitutions. Nitrite, as a reducing agent, could be the indispensable chemical in our food or drink intakes that could render the interior of cancer cells anaerobic. Nitrite, as an oxidation agent, could then be the substrate of the metabolic reaction anaerobic ammonium oxidation (anammox). The source of oxygen would then be mineral-oxygen from the nitrite. PET scan studies have indicated an advanced stage of metabolism, when cancer cells have evolved to encode aerobic glycolysis under hypoxic conditions. We can postulate a hypothesis that predicts the starvation of cancer cells if there is no supply of nitrite in the food-take to the cancer cells as a substrate of anammox metabolism, or if there is no sufficient supply of glucose for glycolysis. We recommend thus to the UK’s National Health Services to look into this matter that nitrite in public water is a health hazard. Such an investigation serves as a clinical trial on the efficacy of diet-treatments to cure cancer.

Author(s):  
V. Grachev ◽  
N. Kurysheva ◽  
O. Plyamina ◽  
V. Lobkovskiy ◽  
E. Nefedova

Проведенный анализ современных нормативноправовых документов и практики оценки физического износа структурно сложных объектов водопроводноканализационного хозяйства показал, что современные методы оценки не учитывают особенности этих объектов. Выявлены факторы, влияющие на структуру показателей оценки физического износа по основным группам и элементам объектов водопроводноканализационного хозяйства. На их основе разработан алгоритм оценки физического износа объектов с применением рискориентированного подхода для трех уровней: объект, технологические элементы объекта (сооружения), функциональные элементы в составе сооружений (здания, оборудование). Использование алгоритма позволяет разработать рекомендации по корректировке периодичности и частоте проведения мониторинга показателей уровня физического износа объектов централизованных систем водоснабжения и водоотведения и их элементов. Практическое применение разработанного алгоритма будет способствовать внедрению современных подходов по управлению рисками, связанными с уровнем физического износа и оценкой вероятности потенциальных негативных последствий природного, антропогенного и другого характера. Внедрение алгоритма позволит также устанавливать уязвимые области и проводить предупредительные мероприятия в отношении возникновения угрозы нарушения обязательных требований, в том числе меры по снижению рисков (техникотехнологическое обновление зданий, сооружений, оборудования). Это необходимо для объективного и обоснованного планирования капитального ремонта, восстановления и развития объектов водопроводноканализационного хозяйства и их элементов.The paper analyzes current regulatory documents and experience in the field of assessing the deterioration of structurally complex water supply and sanitation facilities. The paper shows that modern assessment procedures do not take into account any features of such objects. The paper identifies factors that affect the indicator framework for assessing the physical deterioration of the main groups and components of water supply and sanitation facilities. Based on these factors, the paper proposes an algorithm for assessing the physical deterioration of facilities using a riskoriented approach for three levels: an object itself, its engineering components (facilities), and their functional elements (buildings, equipment). The paper indicates that the use of the algorithm would provide for developing recommendations for adjusting the frequency of monitoring indicators of the physical deterioration level of facilities of public water supply and sanitation systems and their elements. The implementation of the developed algorithm would contribute to the successful introduction of advanced approaches to managing risks associated with the level of physical deterioration and assessing the probability of potential negative consequences of natural, anthropogenic, and other origins. The introduction of the algorithm would also allow identifying vulnerable areas and taking preventive measures against the threat of violation of mandatory requirements including measures for reducing risks (technical and engineering renovation of buildings, facilities, equipment). This is required for objective and substantiated planning of overhaul, restoration, and development of water supply and sanitation facilities and their components.


Public Health ◽  
1997 ◽  
Vol 111 (3) ◽  
pp. 179-181
Author(s):  
L Fewtrell ◽  
D Kay ◽  
M Wyer ◽  
G O’Neill

2021 ◽  
Vol 11 (15) ◽  
pp. 6900
Author(s):  
Su-Kyung Sung ◽  
Sang-Won Han ◽  
Byeong-Seok Shin

Skinning, which is used in skeletal simulations to express the human body, has been weighted between bones to enable muscle-like motions. Weighting is not a form of calculating the pressure and density of muscle fibers in the human body. Therefore, it is not possible to express physical changes when external forces are applied. To express a similar behavior, an animator arbitrarily customizes the weight values. In this study, we apply the kernel and pressure-dependent density variations used in particle-based fluid simulations to skinning simulations. As a result, surface tension and elasticity between particles are applied to muscles, indicating realistic human motion. We also propose a tension yield condition that reflects Tresca’s yield condition, which can be easily approximated using the difference between the maximum and minimum values of the principal stress to simulate the tension limit of the muscle fiber. The density received by particles in the kernel is assumed to be the principal stress. The difference is calculated by approximating the moment of greatest force to the maximum principal stress and the moment of least force to the minimum principal stress. When the density of a particle increases beyond the yield condition, the object is no longer subjected to force. As a result, one can express realistic muscles.


2000 ◽  
Vol 74 (6) ◽  
pp. 518-526 ◽  
Author(s):  
Norishige YAMAMOTO ◽  
Ken-ichi URABE ◽  
Masatoshi TAKAOKA ◽  
Kiyoaki NAKAZAWA ◽  
Atsushi GOTOH ◽  
...  

Opflow ◽  
2017 ◽  
Vol 109 ◽  
pp. E320-E330 ◽  
Author(s):  
Robert B. Sowby ◽  
Steven J. Burian

Genetics ◽  
2003 ◽  
Vol 165 (2) ◽  
pp. 667-673 ◽  
Author(s):  
W Jason Kennington ◽  
Julia Gockel ◽  
Linda Partridge

AbstractAsymmetrical gene flow is an important, but rarely examined genetic parameter. Here, we develop a new method for detecting departures from symmetrical migration between two populations using microsatellite data that are based on the difference in the proportion of private alleles. Application of this approach to data collected from wild-caught Drosophila melanogaster along a latitudinal body-size cline in eastern Australia revealed that asymmetrical gene flow could be detected, but was uncommon, nonlocalized, and occurred in both directions. We also show that, in contrast to the findings of a previous study, there is good evidence to suggest that the cline experiences significant levels of gene flow between populations.


The present study was conducted Bathinda, Fazilka, and Muktsar of Punjab to examine the socio-economic and general profile of goat farmers, studying a total sample of 88 goat farmers. Both types of goat farming systems, organized goat farms, and traditional goat farms, were studied with more emphasis on organized goat farms. The sample farmers consisted of 56 organized and 32 traditional goat farmers in the state. It was observed in the study that the education level of organized goat farmers was better compared to traditional goat farmers. A majority of the sample goat farmers had nuclear families. A majority of the farmers (53.57 percent) had goat farms located in the village. Organized goat farms had tube-well as the main source of water supply, whereas traditional goat farms were mainly dependent upon public water supply. Organized goat farmers had relatively higher exposure to training. A vast majority of the goat farmers had their breeding buck.


2006 ◽  
Vol 14 (2) ◽  
pp. 136-141 ◽  
Author(s):  
Irene Ramires ◽  
Kelly Polido Kaneshiro Olympio ◽  
Andréa Gutierrez Maria ◽  
Juliano Pelim Pessan ◽  
Vanessa Eid Silva Cardoso ◽  
...  

OBJECTIVES: The objectives of this study were to assess the fluoride concentration in the public water supply and the prevalence of dental fluorosis in schoolchildren between 7 and 15 years old, living in a peripheral district of the municipality of Bauru. MATERIAL AND METHODS: For this, fifty two water samples were collected on three different days of one week. These samples were analyzed for fluoride by means of the ion-sensitive electrode method (Orion 9609) coupled to a potentiometer (Procyon, model 720). In this method, 1.0 mL of TISAB II (Orion) was added to 1.0 mL of the sample. For the epidemiological survey of fluorosis, 52 schoolchildren of both genders, aged between 7 and 15 were assessed, with prior authorization from their caretakers. Only one person examined the children, after supervised toothbrushing and drying with cotton wool rolls. The TF index was used. RESULTS: The fluoride concentrations in the water samples ranged from 0.62 to 1.20 mg/L, with a mean of 0.9 mg/L. The prevalence of dental fluorosis was 33%, with severity ranging from TF1 to TF4 (Kappa of 0.73 and concordance of 83.33%). CONCLUSIONS: The results from the analysis of water samples indicated a fluoride concentration greater than recommended for Bauru. The fluorosis levels found were higher than expected for a peripheral district, in which water is one of the few sources of fluoride.


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