scholarly journals SYNTHESIS, CHARACTERIZATION, AND ANTHELMINTIC ACTIVITY OF NOVEL BENZOTHIAZOLE DERIVATIVES CONTAINING INDOLE MOIETIES

2019 ◽  
pp. 321-325
Author(s):  
ALETI RAJAREDDY ◽  
SRINIVAS MURTHY M
Keyword(s):  
Spectral Analysis ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Magnetic Resonance ◽  
Fourier Transform Infrared Spectroscopy ◽  
Anthelmintic Activity ◽  
Mass Spectral Analysis ◽  
Standard Drug ◽  
Mass Spectral ◽  
Benzothiazole Derivatives

Objective: The objective of this study was to synthesize and evaluate the anthelmintic activity (AA) of novel benzothiazole derivatives containing indole moieties (BDIM). Methods: The present works which involve the substituted isatin Schiff bases undergo acetylating and reacting with 2-aminobenzothiazole to give novel BDIM. Results: All the newly synthesized molecules (5a-5o) were characterized by Fourier-transform infrared spectroscopy, H_nuclear magnetic resonance, and mass spectral analysis along with physical data. The biological potentials of the newly synthesized compounds are evaluated for their AA using an Indian earthworm (Pheretima posthuma), and albendazole was used as standard drug. Conclusion: The synthesized compound 5f, 5n, and 5o showed good AA, whereas others exhibited significant activities.

Study on Preparation and Properties of Starch and 4-Phenolsuflonate Graft Copolymer with HRP Catalysis

2010 ◽  
Vol 129-131 ◽  
pp. 837-841 ◽  
Author(s):  
Sheng Hua Lv ◽  
Yan Fen Ma ◽  
Rui Gong ◽  
Xiao Liang Yan ◽  
Ming Ming Hou
Keyword(s):  
Mechanical Properties ◽  
Nuclear Magnetic Resonance ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Magnetic Resonance ◽  
Horseradish Peroxidase ◽  
Fourier Transform Infrared Spectroscopy ◽  
Graft Copolymer ◽  
Fourier Transform Infrared ◽  
Structure And Properties

Degraded starch was reacted with 4-phenolsuflonate (PHS) in water in the presence of horseradish peroxidase (HRP) catalyst/H2O2/acetylacetone (ACAC) to give starch and PHS graft copolymers. The structure and properties of the graft copolymer are characterized by Fourier Transform Infrared spectroscopy (FTIR), Nuclear　Magnetic　Resonance (NMR). The retanned leather exhibits excellent increased thickness and softness, good dyeing ability and eligible mechanical properties.

Gas-Liquid Chromatographic Derivatization and Chromatography of N-Methylcarbamate Methoxy Derivatives Formed with Trimethylanilinium Hydroxide

1982 ◽  
Vol 65 (6) ◽  
pp. 1452-1456
Author(s):  
Leonard Ogierman
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Spectral Analysis ◽  
Magnetic Resonance ◽  
Infrared Absorption Spectroscopy ◽  
Mass Spectral Analysis ◽  
Liquid Chromatograph ◽  
Mass Spectral ◽  
Carbamate Insecticides ◽  
Synthetic Standard ◽  
Liquid Chromatographic

Abstract Carbamate insecticides injected into a gas-liquid chromatograph react with trimethylanilinium hydroxide to give derivatives that have good gas-liquid chromatographic properties. The substituted phenyl N-methylcarbamates give methoxy derivatives by this procedure. Chromatographic response was linear with increased concentration for the synthetic standard and the on-column methylation products of the examined substances. The standards obtained were identified by ultraviolet and infrared absorption spectroscopy, as well as by nuclear magnetic resonance and mass spectral analysis.

scholarly journals Isolasi Senyawa Metabolit Sekunder dari Ekstrak Metanol Kulit Batang Bauhinia semibifida Roxb. dan Uji Aktivitas Antioksidan

2021 ◽  
Vol 17 (1) ◽  
pp. 132
Author(s):  
Haiyul Fadhli ◽  
Nur Fitria Rohmatul Ummah ◽  
Noveri Rahmawati
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Antioxidant Activity ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Magnetic Resonance ◽  
Vitamin C ◽  
Fourier Transform Infrared Spectroscopy ◽  
Fourier Transform Infrared ◽  
Proton Nuclear Magnetic Resonance ◽  
H Nmr

<p>Kulit batang <em>Bauhinia semibifida </em>Roxb. telah lama digunakan sebagai obat tradisional oleh masyarakat Melayu Lingga, Kepulauan Riau. Penelitian ini bertujuan untuk mengisolasi dan menguji aktivitas antioksidan senyawa metabolit sekunder dari ekstrak metanol kulit batang <em>B. semibifida </em>Roxb. Tiga isolat murni berupa satu senyawa alkaloid (BR1) dan dua senyawa flavonoid (BR2 dan BR3) telah berhasil diisolasi dengan cara ekstraksi menggunakan metode maserasi dan dilanjutkan fraksinasi dengan metode kromatografi kolom. Uji aktivitas antioksidan dilakukan terhadap isolat dengan metode 2,2 difenil-1-pikrilhidrazil (DPPH). Senyawa isolat BR1 menunjukan IC<sub>50 </sub>&gt;1000 µg/mL dikategorikan tidak aktif sebagai antioksidan, sedangkan senyawa isolat BR2 dan BR3 menunjukan IC<sub>50</sub> 2,92 µg/mL dan 4,39 µg/mL dikategorikan sangat kuat sebagai antioksidan jika dibandingkan dengan vitamin C sebagai kontrol. Berdasarkan evaluasi aktivitas antioksidan senyawa BR2 adalah senyawa pilihan yang dilanjutkan identifikasi dengan spektroskopi <em>Fourier-Transform Infrared Spectroscopy </em>(<em>FTIR</em>) dan <em>Proton Nuclear Magnetic Resonance</em> (<sup>1</sup>H-NMR) sehingga diduga senyawa isolat memiliki struktur dasar senyawa flavonoid.</p><p><strong>Isolation of Secondary Metabolite Compounds of Methanolic Extract of Steam Bark <em>Bauhinia semibifida</em> Roxb. and Their Antioxidant Activites</strong>. Stem bark of <em>Bauhinia semibifida</em> Roxb. has been long consumed as a medicinal herb by Lingga Malaya Ethnic. Therefore, this research aimed to isolate and examines the antioxidant activity of secondary metabolites from methanol extract of stembark of <em>Bauhinia semibifida</em> Roxb. Three pure compounds which are an alkaloid (BR1) and two flavonoids (BR2 and BR3) have been isolated by extraction using maceration method followed by fractionation using column chromatography method. Antioxidant activity assay was carried out by 2,2-Diphenyl-1-Picrylhydrazyl (DPPH) method. Compound BR1 showed IC<sub>50</sub> &gt;1000 µg/mL categorized as inactive as an antioxidant, while compounds BR2 and BR3 showed IC<sub>50</sub> 2.92 µg/mL and 4.394 µg/mL, respectively, categorized as very strong as an antioxidant when compared to vitamin C as a control. Based on the evaluation of the antioxidant activity, the BR2 was selected compound and continued to identification by <em>Fourier-Transform Infrared Spectroscopy </em>(<em>FTIR</em>) and <em>Proton Nuclear Magnetic Resonance</em> (<sup>1</sup>H-NMR) spectroscopy so that the isolate has the basic structure of flavonoid compound.</p>

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