Mean platelet volume/platelet count ratio predicts long-term mortality in patients with infective endocarditis

2020 ◽  
Vol 14 (4) ◽  
pp. 293-302
Author(s):  
Chen Liu ◽  
Yuanyuan Zhou ◽  
Xin He ◽  
Junxiao Ma ◽  
Wenyun Guo ◽  
...  
Keyword(s):  
Platelet Count ◽  
Infective Endocarditis ◽  
Mean Platelet Volume ◽  
Cox Proportional Hazards ◽  
Platelet Volume ◽  
Count Ratio ◽  
Kaplan Meier ◽  
Increased Risk ◽  
All Cause Mortality

Aim: We aimed to examine the association between baseline mean platelet volume/platelet count ratio (MPR) and all-cause mortality in patients with infective endocarditis (IE). Patients & methods: This study analyzed 218 consecutive patients with IE and divided them into four groups based on MPR quartiles. We used Kaplan–Meier survival curves to determine the cumulative survival and Cox proportional hazards models to investigate the association between MPR and all-cause mortality after hospital discharge. Results: Kaplan–Meier curves showed a gradual increase in mortality risk from the lowest MPR quartile to the highest quartile. Multivariate analysis revealed that MPR was an independent predictor of increased risk for all-cause death. Conclusion: Elevated MPR was independently associated with long-term all-cause mortality in patients with IE.

Mean platelet volume and mean platelet volume/platelet count ratio in infective endocarditis

Platelets ◽  
2013 ◽  
Vol 25 (8) ◽  
pp. 559-561 ◽  
Author(s):  
Sun Young Cho ◽  
You La Jeon ◽  
Weon Kim ◽  
Woo-Shik Kim ◽  
Hee Joo Lee ◽  
...  
Keyword(s):  
Platelet Count ◽  
Infective Endocarditis ◽  
Mean Platelet Volume ◽  
Platelet Volume ◽  
Count Ratio

Mean platelet volume/platelet count ratio as a predictor of long-term mortality after non-ST-elevation myocardial infarction

Platelets ◽  
2011 ◽  
Vol 22 (8) ◽  
pp. 557-566 ◽  
Author(s):  
Basem Azab ◽  
Estelle Torbey ◽  
Jasvinder Singh ◽  
Meredith Akerman ◽  
Georges Khoueiry ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Platelet Count ◽  
Mean Platelet Volume ◽  
St Elevation Myocardial Infarction ◽  
Platelet Volume ◽  
Count Ratio ◽  
St Elevation ◽  
Long Term Mortality

Acute and Chronic Changes in Platelet Volume and Count After Cardiopulmonary Bypass Induced Thrombocytopenia in Man

1987 ◽  
Vol 57 (01) ◽  
pp. 55-58 ◽  
Author(s):  
J F Martin ◽  
T D Daniel ◽  
E A Trowbridge
Keyword(s):  
Platelet Count ◽  
Mean Platelet Volume ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Control Group ◽  
Artery Bypass Graft ◽  
Platelet Volume ◽  
Young Males ◽  
The Mean

SummaryPatients undergoing surgery for coronary artery bypass graft or heart valve replacement had their platelet count and mean volume measured pre-operatively, immediately post-operatively and serially for up to 48 days after the surgical procedure. The mean pre-operative platelet count of 1.95 ± 0.11 × 1011/1 (n = 26) fell significantly to 1.35 ± 0.09 × 1011/1 immediately post-operatively (p <0.001) (n = 22), without a significant alteration in the mean platelet volume. The average platelet count rose to a maximum of 5.07 ± 0.66 × 1011/1 between days 14 and 17 after surgery while the average mean platelet volume fell from preparative and post-operative values of 7.25 ± 0.14 and 7.20 ± 0.14 fl respectively to a minimum of 6.16 ± 0.16 fl by day 20. Seven patients were followed for 32 days or longer after the operation. By this time they had achieved steady state thrombopoiesis and their average platelet count was 2.44 ± 0.33 × 1011/1, significantly higher than the pre-operative value (p <0.05), while their average mean platelet volume was 6.63 ± 0.21 fl, significantly lower than before surgery (p <0.001). The pre-operative values for the platelet volume and counts of these patients were significantly different from a control group of 32 young males, while the chronic post-operative values were not. These long term changes in platelet volume and count may reflect changes in the thrombopoietic control system secondary to the corrective surgery.

Impact of Baseline Neutrophil-to-Lymphocyte Ratio on Long-Term Prognosis in Patients With Atrial Fibrillation

Angiology ◽  
2021 ◽  
pp. 000331972110004
Author(s):  
Shuang Wu ◽  
Yan-min Yang ◽  
Jun Zhu ◽  
Jia-meng Ren ◽  
Juan Wang ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Continuous Variable ◽  
Cox Proportional Hazards ◽  
Neutrophil To Lymphocyte Ratio ◽  
Long Term Outcomes ◽  
Lymphocyte Ratio ◽  
Net Reclassification Improvement ◽  
Increased Risk ◽  
All Cause Mortality

We performed a retrospective analysis involving 1269 patients with atrial fibrillation (AF) to evaluate the predictive value of the neutrophil-to-lymphocyte ratio (NLR) on long-term outcomes. The primary outcomes were all-cause mortality and combined end point events (CEEs). Cox proportional hazards regression analysis and net reclassification improvement (NRI) analysis were performed. During a median follow-up of 3.32 years, 285 deaths and 376 CEEs occurred. With the elevation of the NLR, the incidence of all-cause mortality (2.77, 4.14, 6.12, and 12.18/100 person-years) and CEEs (4.19, 7.40, 8.03, and 15.22/100 person-years) significantly increased. Multivariate Cox analysis indicated that the highest NLR quartile was independently associated with the incidence of all-cause mortality (hazard ratio [HR] = 1.77, 95% CI: 1.19-2.65) and CEEs (HR = 1.66, 95% CI: 1.18-2.33). When the NLR was analyzed as a continuous variable, a 1-unit increment in log NLR was related to 134% increased risk of all-cause mortality and 119% increased risk of CEEs. Net reclassification improvement analysis revealed that NLR significantly improved risk stratification for all-cause death and CEEs by 15.0% and 9.6%, respectively. Neutrophil-to-lymphocyte ratio could be an independent predictor of long-term outcomes in patients with AF.

Mean platelet volume/platelet count ratio in hepatocellular carcinoma

Platelets ◽  
2012 ◽  
Vol 24 (5) ◽  
pp. 375-377 ◽  
Author(s):  
Sun Young Cho ◽  
John Jeongseok Yang ◽  
Eunkyoung You ◽  
Byung-Ho Kim ◽  
Jaejun Shim ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Platelet Count ◽  
Mean Platelet Volume ◽  
Platelet Volume ◽  
Count Ratio
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