Biosense Webster’s QDOT Micro™ radiofrequency ablation catheter

2021 ◽  
Author(s):  
Jean-Yves Wielandts ◽  
Alexandre Almorad ◽  
Gabriela Hilfiker ◽  
Kris Gillis ◽  
Milad El Haddad ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Temperature Sensing ◽  
Power Delivery ◽  
Quality Level ◽  
Ablation Catheter ◽  
Metal Shell ◽  
Short Term ◽  
Irrigation Flow ◽  
Different Characteristics

The QDOT Micro™ catheter (Biosense Webster, Inc., CA, USA) is a new radiofrequency ablation catheter based on the SmartTouch SF™ (Biosense Webster, Inc.). It combines diffuse external irrigation with six thermocouples located within the outer metal shell and three additional microelectrodes in a 3.5 mm-tip contact force radiofrequency catheter. This article focuses on the different characteristics of the catheter, which incorporates the ability of high power delivery, irrigation flow control based on temperature sensing through the six thermocouples and the generation of microelectrograms. An outline of its performance in preclinical and clinical setting is presented, showing promising results, especially concerning procedural efficiency and short-term safety. Additional studies need to confirm long-term effectiveness, and durability studies should evaluate whether superiority on a lesion quality level can be achieved.

scholarly journals THE SCALE OF THE SPREAD OF COVID-19 IN GEORGIA AND EFFECTIVENESS OF PREVENTIVE MEASURES IMPLIMENTED BY THE GOVERNMENT – WHAT DO MODELS SAY?

2020 ◽  
pp. 49-57
Author(s):  
IURI ANANIASHVILI ◽  
LEVAN GAPRINDASHVILI
Keyword(s):  
Machine Learning ◽  
Preventive Measures ◽  
Herd Immunity ◽  
Optimal Level ◽  
Short Term ◽  
Machine Learning Methods ◽  
Data Limitations ◽  
The Government ◽  
Different Characteristics

. In this article we present forecasts of the spread of COVID-19 virus, obtained by econometric and machine learning methods. Furthermore, by employing modelling method, we estimate effectiveness of preventive measures implemented by the government. Each of the models discussed in this article is modelling different characteristics of the COVID-19 epidemic’s trajectory: peak and end date, number of daily infections over different forecasting horizons, total number of infection cases. All these provide quite clear picture to the interested reader of the future threats posed by COVID-19. In terms of existing models and data, our research indicates that phenomenological models do well in forecasting the trend, duration and total infections of the COVID- 19 epidemic, but make serious mistakes in forecasting the number of daily infections. Machine learning models, deliver more accurate short –term forecast of daily infections, but due to data limitations, they struggle to make long-term forecasts. Compartmental models are the best choice for modelling the measures implemented by the government for preventing the spread of COVID-19 and determining optimal level of restrictions. These models show that until achieving herd immunity (i.e. without any epidemiological or government implemented measures), approximate number of people infected with COVID-19 would be 3 million, but due to preventive measures, expected total number of infections has reduced to several thousand (1555-3189) people. This unequivocally indicates the effectiveness of the preventive measures.

Characteristics of elderly metastatic prostate cancer (M1 PC) long-term survivors in the SEER Medicare database receiving androgen-deprivation therapy (ADT)

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e17513-e17513
Author(s):  
N. A. Obeidat ◽  
C. D. Mullins ◽  
E. Onukwugha ◽  
B. Seal ◽  
A. Hussain
Keyword(s):  
Clinical Characteristics ◽  
Population Based ◽  
Short Term ◽  
Time To First Treatment ◽  
Medicare Database ◽  
Different Characteristics ◽  
Lost To Follow Up ◽  
Long Term Survivors

e17513 Background: ADT remains standard treatment for pts with M1 PC, with radiation (RT) and chemotherapy (CT) providing additional palliation. This population-based analysis evaluated if long-term survivors (LT) receiving ADT possessed different characteristics relative to short-term survivors (ST). Methods: Pts age >/= 66y in SEER Medicare diagnosed with M1 PC between 1998 and 2002 and receiving ADT with or without subsequent CT were identified. Median overall survival (OS) for the sample was used as a cut-off to categorize ST and LT pts. Within these categories, demographic, and clinical characteristics were evaluated. Results: 2,665 ADT pts were first identified who had median OS of 26 months (95% CI 24.0 - 27.0). 1,349 pts died at </= 26 months (ST pts), while 1,245 pts survived or were lost to follow-up beyond 26 months (LT pts). Median time to first treatment with ADT was 1 mo in both ST and LT groups. Within this 66y+ population, LT pts were younger (p < 0.0001), more likely to be married (p = 0.0277), and were comprised of lower % of non-Hispanic white pts and higher % of ‘other’ races, but comparable % of African American and White-Hispanics (p = 0.0005). Distributional differences in PSA were detected, but interpreting the results was difficult due to missing or unknown information. Both ST and LT pts received RT and prostatectomy at similar rates, but LT pts had less comorbidities (p = 0.0008), and were more likely to receive CT (p = 0.0026). Conclusions: Long-term survivors were found to have demographic and clinical characteristics that differed from short-term survivors. Evidence regarding how these characteristics simultaneously impact the type and timing of treatment as well as survival deserve more exploration. [Table: see text]

Effectiveness of Aerobic Exercise on Smoking Cessation in Adults: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 18 (2) ◽  
pp. 230-242
Author(s):  
Caroline Pereira Santos ◽  
Mahara Proença ◽  
Tamara dos Santos Gouveia ◽  
Crystian Bitencourt Soares de Oliveira ◽  
Guilherme Yassuki Tacao ◽  
...  
Keyword(s):  
Systematic Review ◽  
Smoking Cessation ◽  
Aerobic Exercise ◽  
Usual Care ◽  
Meta Analysis ◽  
Control Group ◽  
Short Term ◽  
Continuous Abstinence ◽  
Different Characteristics

Background: The specific benefits of aerobic exercises in smoking cessation are unclear, as they have different characteristics, intensities, and durations. The purpose of this systematic review with meta-analysis was to evaluate the effects of aerobic exercise, with or without co-interventions, compared with a control group of cognitive behavior treatment on smoking cessation. Methods: This review was prospectively registered on PROSPERO, and the searches were performed from 2016 to 2018. Randomized controlled trials evaluating the effects of aerobic exercise, with or without nicotine therapy replacement, compared with usual care were included. The primary outcome was smoking cessation defined as the prevalence of those who quit or continuous abstinence. Meta-analysis was calculated using random effects model in the comprehensive meta-analysis software. Results: The authors identified 18 trials reporting data for a total of 2815 participants. There was moderate-quality evidence that aerobic exercise was better than usual care in promoting smoking cessation at short term (11 trials, risk ratio 0.79; 95% confidence interval, 0.66–0.94). However, there were no differences between aerobic exercises and usual care at medium- or long-term follow-ups. Conclusions: According to review, aerobic exercise may be effective in promoting smoking cessation at short-term, but not at medium- and long-term follow-ups.

scholarly journals Openness of Natural Information Processing Systems and Short-Term and Long-Term Memory

2018 ◽  
Vol 155 ◽  
pp. 01026
Author(s):  
Vladimir Shumilov ◽  
Vladimir Syryamkin
Keyword(s):  
Long Term Memory ◽  
Short Term ◽  
Term Memory ◽  
Brain Responses ◽  
Range Of Functions ◽  
Natural Information ◽  
Different Characteristics ◽  
The Brain ◽  
Different Parts

In this paper, various types of memory are considered.Development of the nervous system and the brain of organisms ensures expansion of species with more developed brain. Different characteristics of the brain zones have created different conditions for forming traces of events. The various traces of trace events formed in different parts of the brain provided a wider range of functions and brain responses, which contributed to the survival and expansion of species. The work describes the appearance of memory varieties and the causes of these varieties.

Radiofrequency ablation versus cryoablation for atrioventricular nodal re-entrant tachycardia in children: a value comparison

2016 ◽  
Vol 27 (2) ◽  
pp. 224-228
Author(s):  
Matthew E. Oster ◽  
Zhou Yang ◽  
Kay Stewart-Huey ◽  
Michelle Glanville ◽  
Arlene Porter ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Hospital Costs ◽  
Fixed Costs ◽  
Short Term ◽  
A Value ◽  
Labour Costs ◽  
Acute Success ◽  
The Cost ◽  
Procedure Type

AbstractBackgroundIt is unclear whether cryoablation or radiofrequency ablation offers better value for treating atrioventricular nodal re-entrant tachycardia in children. We aimed to compare the value of these procedures for treating atrioventricular nodal re-entrant tachycardia in children, with value being outcomes relative to costs.MethodsWe performed a retrospective cohort study of all atrioventricular nodal re-entrant tachycardia ablations for children (age⩽18 years) from July, 2009 to June, 2011 at our institution. Costs included fixed costs, miscellaneous hospital costs, and labour costs, and key outcomes were acute and long-term success (6 months) of the ablations. We conducted T-tests and regression analyses to investigate the associations between the ablation procedure type and the cost and success of the ablations.ResultsOf 96 unique cases performed by three paediatric electrophysiologists, 48 were cryoablation only, 42 radiofrequency ablation only, and six were a combination. Acute success was 100% for the cryoablation only and radiofrequency ablation only cases and 83% for the combination cases. There were no notable adverse events. The average total cost was $9636 for cryoablation cases, $9708 for radiofrequency ablation cases, and $10,967 for combination cases (p=0.51 for cryoablation only versus radiofrequency ablation only). The long-term success rate was 79.1% for cryoablation only, 92.8% for radiofrequency ablation only, and 66.7% for the combination (p=0.01 for cryoablation only versus radiofrequency ablation only), but long-term success varied notably by provider.ConclusionsCryoablation and radiofrequency ablation offer similar value in the short term for the treatment of atrioventricular nodal re-entrant tachycardia in children. Differences in long-term success may vary substantially by physician, and thus may lead to differences in long-term value.

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