scholarly journals A Review of Potential Antiviral Drugs and Vaccines to Treat COVID-19

2020 ◽  
Vol 14 (suppl 1) ◽  
pp. 765-774
Author(s):  
Sanjeet Singh ◽  
Jayaram R.
Keyword(s):  
Health Care Workers ◽  
Social Life ◽  
Patient Monitoring ◽  
Web Of Science ◽  
Drug Repurposing ◽  
Patient Handling ◽  
Care Workers ◽  
The World ◽  
Muscle Ache

Coronavirus disease 19 (COVID-19) is a challenge to the whole humanity. COVID-19 was first reported in China and rigorous researches are going on for developing vaccine for the pandemic. This review was prepared by following PRISMA guidelines and used the resources from the Web of Science and PubMed. This research focuses on the niches of symptoms and vaccines for COVID-19. The research for vaccine involves research for new vaccine and drug repurposing. Out of various drug repurposing options, Remdesivir, and Favipiravir, Chloroquine and Lopinavir/Ritonavir were found to be the popular ones for treating COVID-19 patients across the world. Even though there are concerns regarding asymptotic patients, the most dominant symptoms of COVID-19 are fever and cough, followed by Dyspnoea and muscle ache. This review concludes that the COVID-19 related research should focus on developing immunity vaccines, and repurposing of drugs. Research on the problems of quarantine life, patient monitoring, and usage of information technology in facing COVID-19 will improve the quality of patient handling during the pandemic. The research on the effectiveness of various models of lockdown and regulation of social life during lockdown periods, improving the safety of health care workers in the workplace will definitely help the governments in their fight against COVID-19.

Impact of California Safe Patient Handling Legislation: Health Care Workers’ Perspectives

2021 ◽  
Vol 69 (3) ◽  
pp. 124-133
Author(s):  
Soo-Jeong Lee ◽  
Laura Stock ◽  
Victoria Michalchuk ◽  
Kelsie Adesoye ◽  
Kathleen Mullen
Keyword(s):  
Health Care ◽  
San Francisco ◽  
Health Care Workers ◽  
Qualitative Content Analysis ◽  
Management Support ◽  
Patient Handling ◽  
Safe Patient Handling ◽  
Care Workers ◽  
Policies And Programs ◽  
Safe Practices

Background: Musculoskeletal injuries from patient handling are significant problems among health care workers. In California, legislation requiring hospitals to implement safe patient handling (SPH) programs was enacted in 2011. This qualitative study explored workers’ experiences and perceptions about the law, their hospital’s SPH policies and programs, patient handling practices, and work environment. Methods: Three focus groups were conducted with 21 participants (19 nurses and 2 patient handling specialists) recruited from 12 hospitals located in the San Francisco Bay Area and San Joaquin Valley. Qualitative content analysis was used for data analysis. Results: Multiple themes emerged from diverse experiences and perceptions. Positive perceptions included empowerment to advocate for safety, increased awareness of SPH policies and programs, increased provision of patient handling equipment and training, increased lift use, and improvement in safety culture. Perceived concerns included continuing barriers to safe practices and lift use such as difficulty securing assistance, limited availability of lift teams, understaffing, limited nursing employee input in the safety committee, blaming of individuals for injury, increased workload, and continuing injury concerns. Participants indicated the need for effective training, sufficient staffing, and management support for injured workers. Conclusions/Application to Practice: This study identified improvements in hospitals’ SPH programs and practices since the passage of California’s SPH law, as well as continuing challenges and barriers to safe practices and injury prevention. The findings provide useful information to understanding the positive impacts of the SPH law but also notes the potential limitations of this legislation in the view of health care workers.

scholarly journals Rapamycin: Drug Repurposing in SARS-CoV-2 Infection

2021 ◽  
Vol 14 (3) ◽  
pp. 217
Author(s):  
Jiri Patocka ◽  
Kamil Kuca ◽  
Patrik Oleksak ◽  
Eugenie Nepovimova ◽  
Martin Valis ◽  
...  
Keyword(s):  
Literature Review ◽  
Human Health ◽  
World Economy ◽  
Web Of Science ◽  
Drug Repurposing ◽  
Final Analysis ◽  
High Rate ◽  
Suitable Candidate ◽  
Promising Strategy ◽  
The World

Since December 2019, SARS-CoV-2 (COVID-19) has been a worldwide pandemic with enormous consequences for human health and the world economy. Remdesivir is the only drug in the world that has been approved for the treating of COVID-19. This drug, as well as vaccination, still has uncertain effectiveness. Drug repurposing could be a promising strategy how to find an appropriate molecule: rapamycin could be one of them. The authors performed a systematic literature review of available studies on the research describing rapamycin in association with COVID-19 infection. Only peer-reviewed English-written articles from the world’s acknowledged databases Web of Science, PubMed, Springer and Scopus were involved. Five articles were eventually included in the final analysis. The findings indicate that rapamycin seems to be a suitable candidate for drug repurposing. In addition, it may represent a better candidate for COVID-19 therapy than commonly tested antivirals. It is also likely that its efficiency will not be reduced by the high rate of viral RNA mutation.

ANALYSIS OF THE ROLE OF THE ECONOMIST IN PUBLIC HEALTH

Vestnik ◽  
2021 ◽  
pp. 313-316
Author(s):  
И.Г. Турсумбай ◽  
Л.К. Кошербаева
Keyword(s):  
Public Health ◽  
Health Care ◽  
Comparative Analysis ◽  
Health Economics ◽  
Continuous Improvement ◽  
Health Care Workers ◽  
Economic Situation ◽  
Care Workers

Одним из последствий осуществления медицинской деятельности в разнообразных хозяйственных формах является изменение экономического положения работников здравоохранения. От количества и качества их труда зависит экономический результат деятельности лечебно-профилактических учреждений (ЛПУ) в целом. В статье приводится сравнительный анализ занимающихся подготовкой экономистов в области здравоохранения по различным критериям. Подчеркивается необходимость непрерывного совершенствования подготовки управленческих кадров в области экономики здравоохранения в современных условиях развития общества. One of the consequences of the implementation of medical activities in various economic forms is a change in the economic situation of health care workers. The number and quality of their work depends on the economic result of the activities of medical and preventive institutions (LPU) as a whole. The article presents a comparative analysis of the health economists who are engaged in training according to various criteria. The necessity of continuous improvement of training of managerial personnel in the field of health economics in the modern conditions of society development is emphasized.

The Neutrality of Switzerland

1919 ◽  
Vol 13 (2) ◽  
pp. 227-241
Author(s):  
Gordon E. Sherman
Keyword(s):  
Social Life ◽  
Red Cross ◽  
Occupied Territory ◽  
The World

It has been finely said of Switzerland that while the present war has demonstrated in a sinister manner Swiss dependence upon its powerful neighbors for fuel and food, and thus for its very existence, nevertheless neither these neighbors nor the world at large could for a moment spare the example of heroism and devotion so constantly and consistently set by the Swiss nation in its political and social life. This quality of devotion has been illustrated during the war not alone by the struggles unavoidable in the maintenance of neutrality, but also in the far-reaching activities of the International Red Cross at Geneva. Indeed, the work accomplished through the agencies of this wonderful organization in the internment and care of wounded soldiers and their repatriation where permissible under belligerent agreement, in the repatriation of civilians driven from occupied territory, the transmission of mail to prisoners, and the discovery of vast numbers of the missing, constitute one of the most striking chapters in the war’s history.

scholarly journals Standardised, quantitative neutralisation responses to SARS-CoV-2 Variants of Concern by convalescent anti-sera from first wave infections of UK Health Care Workers and Patients

2021 ◽  
Author(s):  
Diego Cantoni ◽  
Martin Mayora-Neto ◽  
Angalee Nadesalingam ◽  
David A. Wells ◽  
George W. Carnell ◽  
...  
Keyword(s):  
Health Care Workers ◽  
Healthcare Workers ◽  
World Health Organisation ◽  
World Health ◽  
Care Centre ◽  
International Standard ◽  
Care Workers ◽  
The World ◽  
Antibody Titres ◽  
The Uk

One of the defining criteria of Variants of Concern (VOC) is their ability to evade pre-existing immunity, increased transmissibility, morbidity and/or mortality. Here we examine the capacity of convalescent plasma, from a well defined cohort of healthcare workers (HCW) and Patients infected during the first wave from a national critical care centre in the UK, to neutralise B.1.1.298 variant and three VOCs; B.1.1.7, B.1.351 and P.1. Furthermore, to enable lab to lab, country to country comparisons we utilised the World Health Organisation (WHO) International Standard for anti-SARS-CoV-2 Immunoglobulin to report neutralisation findings in International Units. These findings demonstrate a significant reduction in the ability of first wave convalescent plasma to neutralise the VOCs. In addition, Patients and HCWs with more severe COVID-19 were found to have higher antibody titres and to neutralise the VOCs more effectively than individuals with milder symptoms. Widespread use of the WHO International Standard by laboratories in different countries will allow for cross-laboratory comparisons, to benchmark and to establish thresholds of protection against SARS-CoV-2 and levels of immunity in different settings and countries.

scholarly journals Harmonization of European and Russian standards of evaluation of the quality of delivery of health care in educational organizations

2019 ◽  
Vol 19 (3) ◽  
pp. 157-162
Author(s):  
V. R. Kuchma ◽  
Svetlana B. Sokolova
Keyword(s):  
Health Care ◽  
Health Services ◽  
Medical Care ◽  
Health Care Workers ◽  
Health Professionals ◽  
School Health ◽  
Educational Institutions ◽  
Medical Aid ◽  
Care Workers

Harmonization of European and Russian standards of the quality of the delivery of school health services and competencies for school health professionals allowed to justify the concept of the evaluation of the quality of the delivery of medical help to students in educational institutions. The concept does not prescribe a concrete methodfor the organizing school health services, unified process of the activity of health professionals. The concept consists of 7 groups of indices of quality and competences of health care workers. Quality criteria include the presence of a regulatory framework, indices of benevolence towards children, social equity and access to health care for students, requirements for premises, equipment of medical rooms in schools, cooperation with the administration and teachers of schools, parents and children, the medical community, the requirements for health care workers, a minimum list of services, covering both population and individual needs of students, the secure storage, the management and use ofpersonal medical data of children and adolescents. The competences of the staff of medical units are determined by provided medical services and technologies of the work. Properly medical competences of workers of medical care units for the delivery of medical aid to students are contributed by willingness to ensure the rights of children in the process of health care delivery in the educational organization, skills in the field of communication, sharing of information with children, parents and teachers, cooperation with colleagues, planning and coordination of the organization of medical care, the provision of sanitary epidemiological well-being of students, informational-elucidative activity for shaping of healthy lifestyle, research activity. Concept is the basis of the algorithm of the evaluation of the quality of the delivery of medical aid to students and quality assessment technology as well by medical organizations and institutions, as in the form of an independent audit of the quality of the delivery of medical aid to students in educational institutions.

Dentofacial Form in the Five-Year-Old Child with Unilateral Cleft Lip and Palate

1994 ◽  
Vol 31 (5) ◽  
pp. 372-375 ◽  
Author(s):  
Frances Mackay ◽  
John Bottomley ◽  
Gunvor Semb ◽  
Christopher Roberts
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Racial Group ◽  
Cephalometric Analysis ◽  
Upper Lip ◽  
Quality Of Treatment ◽  
Care Workers

It is generally believed that studies of outcome for children with clefts of the lip and palate should be based on patients who are in their teens. This means that health care workers who look after these children would have to wait many years until the quality of treatment could be evaluated. In this study, significant differences between two centers, Oslo and Manchester, in facial form at the age of 5 years were detected. Based on cephalometric analysis, children from Manchester were more likely to have a retrognathic maxilla with the upper lip significantly behind the esthetic plane. An important future step may be the setting up of “reference centers” with a large archive of database information for each racial group. This would assist smaller centers in comparing their outcomes.

scholarly journals Predictors of quality of life of medical students and a comparison with quality of life of adult health care workers in Thailand

SpringerPlus ◽  
2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Chaisiri Angkurawaranon ◽  
Wichuda Jiraporncharoen ◽  
Arty Sachdev ◽  
Anawat Wisetborisut ◽  
Withita Jangiam ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Care ◽  
Medical Students ◽  
Health Care Workers ◽  
Adult Health ◽  
Care Workers ◽  
Adult Health Care

scholarly journals Evaluating Safe Patient Handling Systems: Is There a Better Way?

2021 ◽  
Author(s):  
◽  
Heidi Elizabeth Borner
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Health Care Organizations ◽  
Well Being ◽  
Small Sample ◽  
Workplace Culture ◽  
Care Providers ◽  
Patient Handling ◽  
Safe Patient Handling ◽  
Care Workers

<p>The literature presented here shows that injuries suffered by staff and patients due to patient handling are preventable but patient handling injuries to health care workers and patients remain a costly problem to health care  organizations in many countries. "No Lifting" patient handling policies have been adopted yet health care organizations currently sit amongst the top three worst performing industries in terms of disabling injuries to their employees. A factor that contributes to this situation is the lack of tools for evaluating patient handling systems including workplace culture and climate. This observational study analyzes the responses of 38 nurses from two similar units that use different patient handling systems to test the reliability and validity of the Safe Patient Handling Survey (TM) SPH Survey(TM), a perception survey and improvement tool for employees and employers. The survey contains 55 questions divided into 6 clusters, staff and patient injury and violence questions, and picture questions depicting unsafe techniques. The data were analyzed to see how the SPH Survey(TM) scores correlate with incidents, and its ability to detect differences between the two units. The results of the Pearson and Cronbach(TM) alpha tests show strong reliability, validity and consistency of the SPH Survey(TM). ANOVA comparison of means and Spearman(TM) rho tests shows that higher (better) scores on the SPH Survey(TM) clusters correlate with lower numbers of patient injuries, lower reports of verbal and physical violence episodes, and lower staff injuries. Differences were detected between the units with Unit 2 scoring higher than Unit 1 in all SPH Survey(TM) clusters and scoring lower in staff and patient injuries and violence incidents. Although the analysis was limited by the small sample size, the study has created a sound basis for further investigation. Health care organizations, unions, government bodies, insurers, educational institutions, and researchers must continue to reduce patient handling risk for both health care workers and for patients. The SPH Survey(TM) is shown to be an easy way to reliably evaluate patient handling systems and workplace culture, target improvement initiatives, and continually monitor the level of patient handling risk in the workplace. Low-risk patient handling gives health care providers the means to focus on delivering high quality patient care, without endangering their own health and well-being.</p>

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