scholarly journals Osteomyelitis in Children from Rural Population of Uttar Pradesh

Author(s):  
Dinesh Kumar ◽  
Priya Mehrishi ◽  
Sameer Singh Faujdar ◽  
Satish Kumar ◽  
Amisha Sharma

Occurrence of Staphylococcus aureus in children with osteomyelitis. This study was conducted at K. M. M. C. & Hospital, Mathura (UP). A total of 60 patients with osteomyelitis contributed to this study from October 2017 to October 2019. Patients with known immunodeficiency syndromes were excluded. Specimen collections were meticulously performed to avoid contamination which was accomplished by needle aspiration or surgical sampling. Staphylococcus aureus was recovered in more than half of the cases of osteomyelitis in both infants and children. Amikacin, Clindamycin and Cefazolin were effective in such cases. The distal end of the femur and upper-end tibia were the most common sites of infection where boys were more infected than girls. The haematogenous route was the main cause of the transmission of osteomyelitis in children. Principally Staphylococcus aureus causes the majority of cases of osteomyelitis in children followed by H. influenza, Group B Streptococcus, P. aeruginosa, E. coli and Serratia marcescens.

PEDIATRICS ◽  
1979 ◽  
Vol 64 (3) ◽  
pp. 393-394
Author(s):  
David W. Fraser

Speck et al1 purport to show that Staphylococcus aureus, S epidermidis, and Escherichia coli interfere with colonization of neonates with group B streptococcus. Unfortunately, their documentation is defective. They indicate that, of the sites (nasopharynx or umbilicus) of group B streptococcus. Unfortunately, their documentation is defective. They indicate that, of the sites (nasopharynx or umbilicus) of group B colonization in 268 3-day-old infants, S aureus was found in only 15% (6/40), S epidermidis in only 29% (12/41), and E coli in only 24% (10/41).


PEDIATRICS ◽  
1969 ◽  
Vol 44 (1) ◽  
pp. 49-57 ◽  
Author(s):  
John H. Dossett ◽  
Ralph C. Williams ◽  
Paul G. Quie

The bactericidal capacity of newborn infants' whole blood for E. coli was deficient compared to the mothers, and attempts were made to identify cellular or humoral factors responsible for this deficiency. Separated polymorphonuclear leukocytes from newborn infants were found to be similar to polymorphs from mothers in capacity to engulf and kill E. coli and other bacteria so that cellular deficiency was not evident. Comparison of the serum opsonic capacity of newborn infants' and mothers' sera revealed deficient opsonic capacity for E. coli in newborn sera. The mean opsonic titer for E. coli was 46.7 in mothers and 4.3 in neonates. Serum opsonic titers for Staph. aureus and group B streptococcus were similar. The opsonic capacity for all bacterial species was decreased when the sera were heated or decomplemented with immune complexes indicating the phagocytosis amplifying role of complement. The newborn-maternal difference in opsonic capacity for E. coli was presumably a result of deficient 19S antibodies, the primary opsonic antibodies for this organism. Maternal 19S serum fractions alone, however, showed no opsonic capacity for E. coli. Addition of a complement source (newborn serum absorbed with E. coli) revealed the opsonic capacity of these 19S maternal serum fractions for E. coli. Antibodies in 19S serum fractions therefore are efficient opsonins for E. coli; however, complement is necessary to demonstrate their opsonic potential.


1995 ◽  
Vol 115 (2) ◽  
pp. 261-266 ◽  
Author(s):  
Eduardo Villamor ◽  
Francisco Pérez-Vizcaíno ◽  
Teresa Ruiz ◽  
Juan C. Leza ◽  
Manuel Moro ◽  
...  

Author(s):  
Ítalo Fernando Penha da Silva ◽  
José Maria Henriques Serruya Júnior ◽  
Tayonara Borges Gonçalves Góes ◽  
Bruno Gomes de Noronha ◽  
Cláudio Alberto Gellis de Mattos Dias ◽  
...  

Las infecciones del tracto urinario (ITU) representan un problema de salud mundial. La resistencia a los microbianos, debido a la presión selectiva de antibióticos, tiene una influencia directa en la evolución y el impacto de estas infecciones. El objetivo de este trabajo fue identificar el perfil de susceptibilidad a los antimicrobianos de los uropatógenos aislados en muestras de urocultura de un laboratorio privado en la ciudad de Macapá/AP. Se trata de un estudio cuantitativo, retrospectivo y transversal, utilizando una base de datos de laboratorio. Los datos se recopilaron de los resultados de las uroculturas con antibiograma analizados de enero a diciembre de 2019. El presente estudio evaluó 3.510 uroculturas, llevadas a cabo durante el período de estudio, de las cuales 1.269 tuvieron crecimiento bacteriano, equivalente al 36,15%. Entre los resultados positivos, encontramos la bacteria Escherichia coli (66,59%), Staphylococcus aureus (32,62%), colonias mixtas de E. coli y S. aureus (0,47%), Staphylococcus saprophyticus (0,24%) y Serratia marcescens (0,08%). El género masculino fue responsable del 16,35% (n.o 574) de las uroculturas analizadas, mientras que la población femenina fue del 83,65% (n a 2936). Al analizar la distribución de bacterias aisladas por género, los machos fueron considerados un factor protector con un 42% menos de posibilidades de presentar bacterias en la orina. La bacteria E. coli fue el patógeno predominante en estas infecciones tanto en sexos como en todos los grupos de edad.


1997 ◽  
Vol 41 (5) ◽  
pp. 1173-1174 ◽  
Author(s):  
L A Meyn ◽  
S L Hillier

Vaginal group B streptococcus (GBS) and Escherichia coli isolates were tested for their susceptibilities to ampicillin. All 414 GBS isolates tested were susceptible to ampicillin; the MIC at which 90% of the isolates were inhibited (MIC90) was 0.125 microg/ml, and the range was 0.06 to 0.25 microg/ml. The MIC50 for the 342 E. coli isolates tested was 4.0 microg/ml, and 27% were resistant to ampicillin.


2021 ◽  
Author(s):  
lydiariver not provided

Group B Streptococcus agalactiae has CAMP factor which allow it to hemolized zones when it is grown on blood agar plates near to Staphylococcus aureus ATCC 25293 colonies, this effect is brought about by Staphylococcus aureus sphingomyelinase.


Author(s):  
Rita P. Verma ◽  
Archana Kota ◽  
Joshua Fogel

Objective The immediate postnatal rectal (RC) and nasopharyngeal colonization (NPC), their prevalence, taxa, and associated characteristics were investigated in sick term infants admitted to the neonatal intensive care unit. Study Design In a retrospective cohort single center study, nasopharyngeal (NPCx) and rectal (RCx) microbial cultures were obtained within 20 minutes of birth in mild-to- moderate sick term infants. Associations between the colonization and maternal–neonatal variables, including early neonatal course, were analyzed via logistic regression analysis. Results A total of 154 term infants were admitted for respiratory distress, hypoglycemia, maternal chorioamnionitis (CHO), and suspected neonatal sepsis; out of which, 80 (52%) were NPCx-positive (+) infants. The duration of rupture of membrane (ROM) was higher (15.5 ± 10.0 vs. 11.3 ± 11.0 hours, p = 0.02), while the respiratory support requirement (16.3 vs. 29.7%, p = 0.04) and occurrence of maternal group B Streptococcus (GBS) colonization lower (15.0 vs. 35.1%, p = 0.01) in NPCx+ infants. ROM increased (odds ratio [OR]: 1.04, 95% confidence interval [CI]: 1.01–1.07), and maternal GBS colonization decreased the odds of positive nasopharyngeal cultures (OR: 0.31, 95% CI: 0.14–0.72). The major microorganisms isolated were Staphylococcus epidermidis (41%), α hemolytic Streptococcus (AHS; 16%), Escherichia coli (13%), and GBS (1.06%). Among the enrolled infants, 44 (28.5%) were RCx positive. The need for (11.4 vs. 27.3%, p = 0.03) and days on respiratory support (0.2 ± 0.6 vs. 0.8 ± 2.5, p = 0.03) were lower and the occurrence of CHO higher (41.0 vs. 23.2%, p = 0.04) in the RCx positive infants. Cesarean section (CS) was performed less frequently (18.2 vs. 55.5%, p = 0.001) and decreased the odds of having positive rectal cultures (OR: 0.21, 95% CI: 0.08–0.51). In total, 80% of the RCx positive infants isolated E. coli, and 6.8% Klebsiella. Conclusion In sick term neonates, early NPC is dominated by SE and RC by E. coli. NPC is supported by ROM and declines by maternal GBS colonization, whereas RC decreases with CS. NPC is more common than RC in this population. Key Points


2017 ◽  
Vol 23 (12) ◽  
pp. 974-979 ◽  
Author(s):  
A. Roca ◽  
A. Bojang ◽  
B. Camara ◽  
C. Oluwalana ◽  
K. Lette ◽  
...  

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