scholarly journals Automatic Detection of Mitral Regurgitation from Heart Sounds using SODP of Imperical Mode Decomposition

2021 ◽  
Vol 9 (VI) ◽  
pp. 1874-1877
Author(s):  
Gabbar Jadhav
Keyword(s):  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Heart Valve ◽  
Valve Disease ◽  
Heart Valve Disease ◽  
Heart Valve Diseases ◽  
Mode Decomposition ◽  
The World ◽  
Valve Diseases ◽  
Pcg Signals

In this paper we discussed the heart valve disease. This heart valve disease occur throughout the world due to the more ethical estimation and grow curator of heart valve diseases use the diagnosis for this type of valve disease . Actually Phonocardiogram (PCG) signals are used because it having less price and acquire the signals. In this we learn five different kind of heart areas, Also typical are aortic stenosis, mitral valve prolapse, mitral stenosis and mitral regurgitation.

Abstract 319: Tnf-α and Il-1β Decrease Myofibroblast Differentiation in 3d-cultured Mitral Valve Interstitial Cells

2020 ◽  
Vol 127 (Suppl_1) ◽  
Author(s):  
Amadeus Zhu ◽  
Jane Grande-Allen
Keyword(s):  
Smooth Muscle ◽  
Mitral Valve ◽  
Heart Valve ◽  
Interstitial Cells ◽  
Valve Disease ◽  
Tissue Type ◽  
Heart Valve Diseases ◽  
Valve Interstitial Cells ◽  
Tnf Α ◽  
Valve Diseases

Background: Fibrosis contributes to many heart valve diseases such as calcific aortic valve disease, rheumatic heart disease, and secondary mitral regurgitation. Heart valve leaflets are populated by quiescent, fibroblast-like valve interstitial cells (VICs). During fibrosis, VICs differentiate into activated, myofibroblast-like cells that adversely remodel the extracellular matrix. Activated VICs overexpress α-smooth muscle actin (ACTA2/αSMA) and smooth muscle 22-α (TAGLN/SM22α) and display increased contractility. Tumor necrosis factor alpha (TNF-α) and interleukin 1 beta (IL-1β) have been reported to either promote or inhibit fibrosis, depending on tissue type. Understanding how TNF-α and IL-1β affect VIC activation in the mitral valve of the heart could enable development of pharmaceutical treatments for heart valve diseases, which are currently managed surgically. Methods: To avoid artifactual activation on tissue culture plastic, VICs were encapsulated in biomimetic scaffolds consisting of polyethylene glycol (4% w/v) functionalized with protease-degradable (GGGPQGIWGQGK) and integrin-binding (RGDS) peptides. These 3D cultures were treated with 10 ng/ml TNF-α, 10 ng/ml IL-1β, or vehicle for 2 days in low-serum (1%) media. RNA and protein were measured via qRT-PCR, western blotting, and immunostaining. To measure contractility, VICs were encapsulated in collagen I (2.5 mg/ml) gels and allowed to contract freely for 2 days. Results: TNF-α and IL-1β significantly decreased RNA expression of ACTA2 (TNF-α: -91±6%, IL-1β: -99±1% change vs. vehicle) and TAGLN (TNF-α: -77±9%, IL-1β: -93±1% change). TNF-α and IL-1β also significantly decreased αSMA protein expression (TNF-α: -76±11%, IL-1β: -91±5% change) and the percentage of αSMA-positive cells (vehicle: 21±3%, TNF-α: 13±2%, IL-1β: 13±5% positive). Finally, TNF-α and IL-1β attenuated VIC-mediated collagen gel contraction (vehicle: 81±7%, TNF-α: 71±3%, IL-1β: 61±4% contraction). Conclusions: TNF-α and IL-1β decrease VIC activation in a 3D culture model of the mitral valve. These results reveal novel pathway targets for reducing fibrosis during mitral valve disease. Future work will use this model to study the downstream signaling events that drive VIC de-activation.

CORONARY ARTERY LESIONS IN PATIENTS OVER 50 YEAR OLD WITH VALVULAR HEART DISEASES INDICATED FOR VALVE SURGERY

2016 ◽  
pp. 20-24
Author(s):  
Bang Giap Vo ◽  
Anh Binh Ho ◽  
Van Minh Huynh
Keyword(s):  
Coronary Artery ◽  
Mitral Valve ◽  
Heart Valve ◽  
Right Coronary Artery ◽  
Heart Diseases ◽  
Heart Valve Diseases ◽  
Coronary Artery Lesions ◽  
Circumflex Coronary Artery ◽  
Valvular Heart Diseases ◽  
Valve Diseases

Objectives: To investigate the features of coronary artery lesions in patients over 50 with heart valve diseases and to find out the relationship between the levels of coronary artery lesions and heart valve diseases. Results: In patients over 50 year old with heart valve diseases, the rate of significant coronary artery lesions is 55.5%. In which, significant lesions in the group of both mitral and aorta valve diseases is 44.19%, only mitral valve diseases is of 70%, only aortic valve diseases is of 51.85%. There is a relationship between the severity of mitral valve diseases and right coronary artery lesions (OR 3.74: 1.64 to 8.5, p = 0.0017) and circumflex coronary artery lesions (OR 2.59: 1.16 to 5.75, p = 0.0192). The severity of heart valve lesions in significant coronary artery lesions group is higher than insignificant coronary artery lesions group or normal group. Conclusion: Coronary artery lesions is common in patients > 50 years old with heart valve diseases, there is a relationship between the severity of mitral valve diseases and and right coronary artery lesions and circumflex coronary artery lesions. Key words: coronary artery lesions, mitral valvediseases

Application of Petersen graph pattern technique for automated detection of heart valve diseases with PCG signals

2021 ◽  
Vol 565 ◽  
pp. 91-104
Author(s):  
Turker Tuncer ◽  
Sengul Dogan ◽  
Ru-San Tan ◽  
U. Rajendra Acharya
Keyword(s):  
Heart Valve ◽  
Automated Detection ◽  
Petersen Graph ◽  
Heart Valve Diseases ◽  
Graph Pattern ◽  
Valve Diseases ◽  
Pcg Signals

scholarly journals Perioperative Management of Sectio Caesarea Surgery in Patient With Heart Valve Disorders

2021 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Purwoko Purwoko ◽  
Zidni Afrokhul Athir
Keyword(s):  
Mitral Regurgitation ◽  
Cesarean Section ◽  
Maternal Mortality ◽  
Pulmonary Edema ◽  
Heart Valve ◽  
Mitral Stenosis ◽  
Valve Disease ◽  
Heart Valve Disease ◽  
Normal Limits ◽  
In Pregnancy

<div class="WordSection1"><p>Cardiovascular disease in pregnancy is common range from 1% to 3 and contributes to 10-15% of maternal mortality. Valvular heart disease accounts for about 25% of cases of cardiac complications in pregnancy and important cause of maternal mortality, some of which are mitral stenosis and mitral regurgitation. Cesarean delivery remains the preferred choice, as it reduces the hemodynamic changes that can occur in normal delivery and allows for better monitoring and hemodynamic management. Our paper provide in-depth information regarding the pathophysiology of heart valve disease in pregnant women and an appropriate perianesthesia approach to obtain a good prognosis. We report a case of a 26-year-old pregnant woman, with obstetric status G1P0A0, 36 weeks’ gestation, body weight 61 kg accompanied by severe mitral regurgitation and moderate mitral stenosis. This patient was planned to undergo elective cesarean section. The patient's condition in the perioperative examination was: GCS E4V5M6, other vital signs within normal limits, SpO2 98-99% in supine position. Other physical and laboratory examinations were also within normal limits. The goal of anesthesia during surgery in patients with heart valve disease undergoing cesarean section maintain pulmonary capillary pressure to prevent acute pulmonary edema. In this case, regional anesthesia of epidural anesthesia was chosen because it can reduce systemic vascular resistance and provide better post-cesarean section pain. The patient's hemodynamics perianesthesia tended to be stable without any complications such as pulmonary edema.</p><p> </p><p> </p></div><br clear="all" /> <br /><p> </p>

Biomechanical Effects of Radiofrequency Ablation With Simultaneous Cryogenic Anchoring

2012 ◽  
Author(s):  
Steven M. Boronyak ◽  
W. David Merryman
Keyword(s):  
Radiofrequency Ablation ◽  
Mitral Valve ◽  
Heart Valve ◽  
Surgical Procedures ◽  
Mitral Valve Prolapse ◽  
Valve Disease ◽  
Heart Valve Disease ◽  
Regurgitant Flow ◽  
Open Chest

Mitral valve (MV) disease is the most common form of heart valve disease, occurring in approximately 2% of the population and resulting in 43,000 open-chest surgical procedures every year [1]. One subtype is mitral valve prolapse (MVP), which is often characterized by severe regurgitant flow, thickened and enlarged leaflets, and disrupted and mechanically compromised collagen architecture.

scholarly journals Heart valve operations associated with reduced risk of death from mitral valve disease but other operations associated with increased risk of death: a national population-based case–control study

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Ruo-Ling Li ◽  
Ci-Wen Luo ◽  
Yung-Chyuan Ho ◽  
Shiuan-Shinn Lee ◽  
Yu-Hsiang Kuan
Keyword(s):  
Mitral Valve ◽  
Heart Valve ◽  
Mitral Valve Disease ◽  
Population Based ◽  
Valve Disease ◽  
Heart Valve Disease ◽  
Risk Of Death ◽  
Increased Risk ◽  
Valve Operation ◽  
Respiratory Conditions

Abstract Background Mitral valve disease is the most common heart valve disease worldwide. Heart valve operation is the predominant treatment strategy for heart valve disease. This study analyzed the death risk from heart valve disease with respect to the frequency of heart valve operation and other operations in patients with mitral valve disease. Materials and methods We conducted a retrospective nationwide population-based case–control study using a claims dataset from Taiwan’s National Health Insurance Research Database. The case and control groups enrolled mitral valve disease patients from 2002 to 2013 who had either underwent an heart valve operation procedure or not, respectively. Conditional logistic regression was estimated the odds ratios (ORs) associated with various risk factors for heart valve operation-related death, including other operations and comorbidities. Results A total of 25,964 patients with mitral valve disease were recruited for the study and divided into heart valve operation (600 patients) and non-heart valve operation (25,364 patients) groups. After matching, a total of 1800 non-heart valve operation patients were selected for final analysis. Heart valve operation was associated with decreased risk of death (adjusted OR [aOR] 0.439), but operations related to other cardiovascular disease (CVD, aOR 3.691), respiratory conditions (aOR 3.210), and the urinary system (aOR 1.925) were associated with increased risk of death for patients with mitral valve disease. Patients with mitral valve disease and diabetes (aOR 1.505), chronic kidney disease (CKD, aOR 3.760), or emphysema (aOR 2.623) also had a higher risk of death. Patients who underwent more heart valve operations had a lower risk of death from mitral valve disease, but patients who underwent more other operations had a higher risk of death from mitral valve disease. Conclusions The death risk for patients with mitral valve disease patients could be lowered by more frequently performing heart valve operations. However, the risk of death is increased for patients with mitral valve disease who more frequently undergo other operations, chiefly those for other CVD system, respiratory conditions, and urinary system, or have comorbidities such as diabetes, chronic kidney disease, and emphysema.

scholarly journals Mitral Valve Surgery in a Patient 50 Years after a Pneumonectomy

2019 ◽  
Vol 08 (01) ◽  
pp. e14-e17
Author(s):  
Hartwig H. C. von Oehsen ◽  
Benjamin A. Högerle ◽  
Christian Giebels ◽  
Hans-Joachim Schäfers
Keyword(s):  
Mitral Valve ◽  
Heart Valve ◽  
Testicular Tumor ◽  
Mitral Valve Surgery ◽  
Valve Disease ◽  
Heart Valve Disease ◽  
Case Presentation ◽  
Valve Reconstruction ◽  
The Subject ◽  
Tricuspid Valve Reconstruction

Background Patients who survive long after pneumonectomy may develop heart valve disease. The consecutive operations can be complex because of the challenging anatomical conditions and the limited physiologic reserves of the patient. Case Presentation The subject is a 78-year-old patient who underwent a left-sided pneumonectomy for a metastasized testicular tumor 50 years ago. At 32 and 37 years postpneumonectomy, mitral regurgitation was manifested, and valve repair was performed. Bioprosthetic mitral valve replacement and tricuspid valve reconstruction became necessary 44 years postpneumonectomy. The patient was fully recovered. Conclusion In case of relevant heart valve disease after pneumonectomies, heart valve surgeries are feasible.

Radiofrequency Ablation With a Cryogenically Cooled Catheter to Percutaneously Treat Mitral Valve Prolapse

2011 ◽  
Author(s):  
Steven M. Boronyak ◽  
W. David Merryman
Keyword(s):  
Radiofrequency Ablation ◽  
Mitral Valve ◽  
Heart Valve ◽  
Surgical Procedures ◽  
Mitral Valve Prolapse ◽  
The Elderly ◽  
Valve Disease ◽  
Heart Valve Disease ◽  
Regurgitant Flow ◽  
Open Chest

Mitral valve (MV) disease is the most common form of heart valve disease, occurring in approximately 2% of the population and resulting in 43,000 open-chest surgical procedures every year [1]. One subtype is mitral valve prolapse (MVP), which primarily affects the elderly and is often characterized by severe regurgitant flow, thickened and enlarged leaflets, and disrupted and mechanically compromised collagen architecture.

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