scholarly journals POTENSI BIJI JINTAN HITAM (NIGELLA SATIVA) DALAM REGENERASI PANKREAS SECARA ENDOGEN PADA DIABETES MELLITUS TIPE-2

2017 ◽  
Vol 13 (2) ◽  
pp. 76
Author(s):  
Fathiyah Safithri
Keyword(s):  
Diabetes Mellitus ◽  
Nigella Sativa ◽  
Diabetes Mellitus Type ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Diabetes Melitus

Penurunan massa sel-β pankreas terjadi pada sebagian besar pasien diabetes melitus tipe-II dan hal ini berlangsung secara progresif. Pankreas merupakan salah satu organ yang mempunyai kemampuan meregenerasi dirinya sendiri dalam upaya mempertahankan massa sel-β. Regenerasi dapat terjadi melalui replikasi sel-β matur, diferensiasi/ transdiferesiasi sel punca/progenitor. Keadaan resistensi insulin yang berlangsung secara kronik menyebabkan kemampuan regenerasi tersebut menurun. Biji jintan hitam (Nigella sativa) yang mengandung bioaktif thymoquinone, asam oleat, asam linoleat dan saponin berpotensi meningkatkan kemampuan regenerasi pankreas secara endogen melalui stimulasi proses replikasi sel-β, mempengaruhi niche dan mengaktivasi sel punca endogen.Kata kunci : diabetes mellitus type II, massa sel-β pankreas, regenerasi pankreas endogen, replikasi, diferensiasi, jintan hitam

scholarly journals STUDI KUALITATIF TENTANG AKTIFITAS (OLAH RAGA) PADA PENDERITA DIABETES MELLITUS TYPE II DI PUSKESMAS PERIUK JAYA KOTA TANGERANG

2016 ◽  
Vol 3 (2) ◽  
pp. 114-122
Author(s):  
Wasludin Wasludin
Keyword(s):  
Diabetes Mellitus ◽  
Diabetes Mellitus Type ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Diabetes Melitus

Berdasarkan informasi dari pihak puskesmas Periuk Jaya, dari 49 orang penderita DM yang berobat ke Puskesmas Periuk Jaya, kurang dari 45%  dari penderita yang  melakukan olahraga sesuai dengan anjuran kesehatan dalam rangka membantu mengontrol kadar gula darah padahal mereka sudah mendapat penjelasan tentang aktifitas (olah raga) yang baik bagi penderita diabetes melitus. Beberapa orang dari mereka mengaku alasan tidak melakukan olah raga tersebut karena tidak memahami, kesibukan, dan beberapa alasan lain yang  belum diketahui, (Dinkes Kota Tangerang, 2014) Penelitian ini menggunakan desain penelitian  kualitatif dengan menggunakan teknik pengumpulan data melalui fokus group diskusi (FGD) pada populasi (informan) yaitu penderita diabates mellitus type II yang berobat ke Puskesmas Periuk Jaya Kota Tangerang sebanyak tujuh (tujuh) orang. Analisis dilakukan dengan merangkum pendapat responden tentang aktifitas (olah raga) yang tepat dan benar bagi penderita diabetes melitus type II. Berdasarkan hasil diskusi dengan informan, terdapat 3 orang informan yang sudah melakukan olahraga berupa pus up, site up, jalan-jalan, lari-lari kecil selama 30 menit – 40 menit yang dilakukan sebanyak 4 – 5 kali dalam satu minggu dan bahwa mereka belum mengetahui cara mengukur tepat/tidaknya atau bilamana menghentikan olahraga yang mereka lakukan, mereka menghentikan olahraga apabila sudah capek/lelah, berkeringat, atau sudah mencapai 30 – 40 menit saja.

scholarly journals HUBUNGAN MOTIVASI INTRINSIK DENGAN KEPATUHAN DIET PASIEN DIABETES MELITUS TIPE II DI PUSKESMAS RANOTANA WERU

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Frysty P.I Mamesah ◽  
Max Runtuwene ◽  
Mario Katuuk
Keyword(s):  
Diabetes Mellitus ◽  
Intrinsic Motivation ◽  
Diabetes Mellitus Type ◽  
Dietary Adherence ◽  
Type Ii ◽  
Cross Sectional ◽  
Diabetes Mellitus Type Ii ◽  
Purposive Sampling ◽  
Adherence To Diet ◽  
Diabetes Melitus

Abstract: Diabetes Mellitus is a chronic disease which caused by the dysfunction of beta cells in producing the insulin. One of any interventions that can be applied is a medical nutrition therapy (diet). Non-adherence to this therapy may caused complications. Intrinsic Motivation is one of any factors that takes an important role in adherence to diet, because it is driven by internal rewards from within the individual. The aim: of this study is to know the relation relation between intrinsic motivation and dietary compliance of diabetes mellitus type II in Ranotana Weru's Health Public Center. Number of Samples: 83 respondents are used as the sample of this study. Research method: this research design is uses a cross-sectional; descriptive-correlational method with the purposive sampling approach. The result: shows that p values =0,000 with the significant values 95% equals to p=0,000 < p= 0,005 for the motivation and dietary adherence of Diabetes Mellitus. Conclusion: this study shows that there is a relation between intrinsic motivation and dietary adherence of Diabetes Mellitus Type II in Public Health Center of Ranotana Weru.Keyword : Diabetes Mellitus, Intrinsic Motivation, Dietary AdherenceAbstrak: Diabetes Melitus (DM) merupakan penyakit menahun. Salah satu penatalaksaan Diabetes Melitus ialah terapi nutrisi medis (diet). Faktor yang sangat mempegaruhi kepatuhan diet ialah motivasi intrinsik karena motivasi intrinsik merupakan motivasi yang timbul dari diri sendiri dan rangsangan dari lingkungan. Tujuan: Tujuan penelitian ini ialah untuk mengetahui hubungan motivasi intrinsik dan kepatuhan diet diabetes melitus tipe II di puskesmas ranotana weru manado. Jumlah sampel: jumlah sampel yang peneliti gunakan pada penelitian ini adalah 83 responden. Desain Penelitian: Desain penelitian ini adalah penelitian cross-sectional yang bersifat deskriptif korelatif dengan teknik pendekatan purposive sampling. Hasil Penelitian: Hasil penelitian ini menunjukan bahwa nilai p = 0,000 dengan nilai kemaknaan 95% yang berarti p=0,00 < p= 0,005 untuk motivasi dan kepatuhan diet diabetes mellitus. Kesimpulan: Dapat disimpulkan bahwa dalam penelitian ini adanya hubungan yang signifikan antara motivasi intrinsik dengan kepatuhan diet diabetes mellitus tipe II.Kata Kunci: Diabetes Melitus, Motivasi Intrinsik, Kepatuhan Diet

scholarly journals Quality of Life as an Integrative Indicator of Health Status in Patients with Chronic Hepatitis C and Concomitant Diabetes Mellitus Type II

2016 ◽  
Vol 22 (2) ◽  
pp. 201625
Author(s):  
Oleksandra Marynchak ◽  
Oleksandra Pryshliak ◽  
Oksana Kopchak ◽  
Iryna Hrynchyshyn ◽  
Ludmyla Byderkevych
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Diabetes Mellitus Type ◽  
Type Ii ◽  
Physical And Mental Health ◽  
Diabetes Mellitus Type Ii

The main indicators of quality of life in patients with chronic hepatitis C with concomitant diabetes mellitus type II were studied on the basis of SF-36. A sharp decrease in physical and mental health was observed in patients with combined comorbidity in comparison with the group of patients without concomitant diabetes mellitus type II. Improvement of the patients’ quality of life by all parameters was detected under the influence of alpha-lipoic acid and lactulose use in addition to antiviral therapy.

scholarly journals A study to assess the clinicopathological spectrum of acute complications of diabetes mellitus type II

2020 ◽  
Vol 8 (9) ◽  
pp. 3246
Author(s):  
Kunal Lala ◽  
Viren Bhati ◽  
Divya Lala ◽  
Smita Patil
Keyword(s):  
Diabetes Mellitus ◽  
Early Recognition ◽  
Diabetes Mellitus Type ◽  
Morbidity And Mortality ◽  
Type Ii ◽  
Metabolic Complications ◽  
Complications Of Diabetes ◽  
Diabetes Mellitus Type Ii ◽  
Acute Complications ◽  
Study Population

Background: The acute metabolic complications of diabetes consist of diabetic ketoacidosis (DKA), hyperosmolar non-ketotic coma (HNC), lactic acidosis (LA), and hypoglycemia. All of these are associated with significant morbidity and mortality. These can easily be prevented by early recognition and prompt management. Therefore, this study was conducted to assess the clinicopathological spectrum of acute complications of diabetes mellitus type II.Methods: This observational, analytical study was conducted on 100 patients aged more than 18 years admitted in the ICU with acute complication of Diabetes mellitus Type II. Medical history was recorded. Physical examination and investigations were done and recorded.Results: The mean age of the study population was 55.26±13.13 years. Hypoglycemia was more common (63%) than DKA (37%). Fever and sweating had the overall highest incidence (and were more in patients with hypoglycemia) while stupor, nausea and abdominal pain had the lowest incidence (and were more in patients with DKA). On examination, only one patient of DKA was drowsy. Mean temperature, pulse and respiratory rate were higher in the patients having DKA while blood pressure was higher in patients having hypoglycemia.Conclusions: It can be effectively concluded from the present study that DKA and hypoglycaemia have a broad spectrum of clinicopathological features. But the incidences vary widely. This may help in early recognition of the impending complication and thereby enabling prompt management of the same, reducing the associated morbidity and mortality.  

scholarly journals PECULIARITIES OF STATE OF PROTECTION AND AGGRESSION FACTORS IN PATIENTS WITH DIABETES MELLITUS TYPE II AND GASTROESOPHAGEAL REFLUX DISEASE

2020 ◽  
Vol 1 ◽  
pp. 27-34 ◽  
Author(s):  
Aleksey Oparin ◽  
Anton Kudriavtsev ◽  
Anatoliy Oparin
Keyword(s):  
Diabetes Mellitus ◽  
Blood Flow ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Blood Flow Velocity ◽  
Reflux Disease ◽  
Diabetes Mellitus Type ◽  
Type Ii ◽  
Diabetes Mellitus Type Ii ◽  
Patients With Diabetes

Diabetes mellitus is one of the most serious problems of the clinical medicine. This is determined by the fact that it is followed by multisystemic affects, as well as complications on the side of other organs and systems, among which a special place is occupied by gastroesophageal reflux disease. As for the combination and mutual influence of diabetes mellitus and gastroesophageal reflux disease, this issue has not been studied yet, the data of modern literature are not complete and quite contradictory. The aim of the study: to investigate the state of the factors of aggression and protection of the oesophageal mucosa in patients with diabetes mellitus type II with concomitant gastroesophageal reflux disease without associated pathology. Method. There were two groups of patients under observation. The first group included 45 patients with diabetes mellitus type II with concomitant gastroesophageal reflux disease (26 men and 19 women). The second group included 38 patients with gastroesophageal reflux disease without associated pathology – 20 men and 18 women. By sex, age, body weight, Helicobacter pylori infection, smoking and alcohol consumption, both groups were comparable. The surveillance program included determining the compensation ratio of carbohydrate metabolism and the state of the factor. The antioxidant protection factor was assessed by the level of catalase activity in the blood serum, as well as by the diameter of the celiac trunk and the blood flow velocity in it. Statistical processing of the obtained data was carried out with the aid of the program WINDOWS STATISTIKA 6.0. For all types of analysis, differences were considered statistically significant with p<0.05. Results. During the study, we found that in patients with diabetes mellitus type II with concomitant gastroesophageal reflux disease, as well as in patients with gastroesophageal reflux disease without associated pathology, the level of pH-metry was reduced, but with varying measures of confidence. At the same time, we found that patients with GERD without associated pathology had a decrease in the blood flow velocity in the celiac trunk. Concurrently, we ascertained that the decrease in the blood flow velocity in patients of both groups reduced the diameter of the celiac trunk. Conclusions. In patients with diabetes mellitus type II, concomitant gastroesophageal reflux disease has a subtle clinical presentation that is affected by a significant decline in mucosal sealing protection factors. In patients with GERD without associated pathology, typical clinical manifestations, accompanied by inflammation, acid regurgitation and dyspepsia, are more vivid.

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