Solid Dispersion: Solubility Enhancement Technique of Poorly Water Soluble Drug
2020 ◽
Vol 10
(1)
◽
pp. 173-177
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Keyword(s):
Solid dispersion is a technique which is widely and successfully applied to improve the solubility, dissolution rates and consequently the bioavailability of poorly soluble drugs. Dispersion of one or more active ingredients (hydrophobic) is done with an inert carrier (hydrophilic) at solid-state prepared by fusion method, solvent, and melting solvent method. In this review article, we have focused on the methods of preparation, advantages, disadvantages and characterization of the solid dispersions. Keywords: Solid dispersion; dissolution; solubility.
2016 ◽
Vol 6
(5)
◽
pp. 540-550
◽
2012 ◽
Vol 506
◽
pp. 307-310
◽
2011 ◽
Vol 415
(1-2)
◽
pp. 83-88
◽
2020 ◽
Vol 11
(01)
◽
pp. 20-24
1970 ◽
Vol 1
(4)
◽
pp. 349-356
Keyword(s):