scholarly journals Results and experiences after 1000 IVF cycles at the Clinic for gynecology and obstetrics in Novi Sad

2011 ◽  
Vol 64 (11-12) ◽  
pp. 565-569
Author(s):  
Vesna Kopitovic ◽  
Stevan Milatovic ◽  
Aleksandra Trninic-Pjevic ◽  
Artur Bjelica ◽  
Irena Bujas ◽  
...  

Introduction. Infertility affects 15-17% of reproductive age couples in our country, and 10-15% of couples worldwide. The aim of this paper was to present results and experience gained after the first 1000 cycles of the national In Vitro Fertilization (IVF) program, to offer professional standard of work in our country and to compare it with results obtained in Europe and worldwide. Material and methods. The study prospectively included 1000 women who had undergone national In Vitro Fertilization program from October 2006 until November 2009 at the Department of Gynecology and Obstetrics, Clinical Center of Vojvodina, Novi Sad. Results. The analysis included 1000 in vitro fertilization cycles. Male factor infertility was the leading cause (56.9%) followed by tubal factor (45.9%). The classic method of in vitro fertilization constituted 72.3% of all cycles, while intracytoplasmic sperm injection (ICSI) method was used in 27.7% of all cycles. The average number of embryos transferred was 2.67. The cycle cancellation rate was 14.10% and the aspiration rate was 94.40%. The clinical pregnancy and live birth rate were 33.41% and 26.78% per embryo transfer, respectively. Discussion and conclusion. The results in our study showed that in our setting there are far less intracytoplasmic sperm injection cycles compared with the European average of 66.5% of all fresh cycles, and that we transferred more embryos on average. Our success rates are comparable with those in other European countries where the clinical pregnancy rates per aspiration and per transfer for in vitro fertilization were 29 and 32.4%, respectively in the period of observation. For intracytoplasmic sperm injection, the corresponding rates were 29.9 and 33%.

2012 ◽  
Vol 65 (7-8) ◽  
pp. 315-318 ◽  
Author(s):  
Dejan Mitic ◽  
Vesna Kopitovic ◽  
Jasmina Popovic ◽  
Stevan Milatovic ◽  
Marin Basic ◽  
...  

Introduction. Infertility affects 15-17% of reproductive age couples in our country. In vitro fertilization brought revolution in treatment of this problem, bringing hope to many couples around the world for more than 3 decades. The aim of this paper was to present results and experiences of implementation of this method of treatment at the Clinic of Gynecology and Obstetrics in Nis. Material and Methods. The study included the first 402 women who had undergone in vitro fertilization program at the Clinical Center of Nis. The data were statistically analyzed by basic descriptive methods. The main outcome measures were demographic features, cause of infertility, duration of stimulation, average gonadothropine consumption, number of oocytes per aspiration and embryos transferred, mode of conception as well as clinical pregnancy and aspiration rate. Results. The two main factors were the male infertility and tubal factor inferitily, being 51.61% and 48.39%, respectively. The classical method of in vitro fertilization constituted 72.40% of all cycles, while intra cytoplasmic sperm injection method was used in 27.60% of all cycles. The average number of embryos transferred was 2.75. The cycle cancellation rate was 15.05%. The clinical pregnancy rate per embryo transfer was 35.44%; while the live birth rate per embryo transfer was 26.53%. Discussion and Conclusion. Our success rates are comparable with those in other European countries, where for in vitro fertilization the clinical pregnancy rates per aspiration and per transfer were 29.0 and 32.4%, respectively in the observed period. For intra cytoplasmic sperm injection, the corresponding rates were 29.9 and 33.0%. The main difference from the European average was the average number of transferred embryos and lower percentage rate of intra cytoplasmic sperm injection as a method of conception.


BioMedica ◽  
2020 ◽  
Vol 36 (4) ◽  
pp. 394-399
Author(s):  
Zoofishan Imran ◽  
Haroon Latif Khan ◽  
Rafia Nafees ◽  
Humaira Humayun ◽  
Rameen Nisar

Background and Objective: Obesity is becoming a global issue related to many health problems, and infertility is one of them. It has been established in literature that obesity or increased body mass index (BMI) harms the ability of a woman to conceive. Assisted reproductive techniques e.g., in-vitro fertilization (IVF) and Intracytoplasmic Sperm Injection (ICSI) are helping infertile women to conceive. This study's objective was to analyze the effect of BMI on IVF/ICSI treatment outcomes in infertile women. Methods: This was a retrospective cross-sectional study. Samples of 500 patients aged less than 40 years were selected at a tertiary care infertility center: Lahore Institute of Fertility and Endocrinology, Hameed Latif Hospital. The sample was collected from January 2019 to June 2019. A structured proforma was used to collect information about selected anthropometric measurements and ultrasonography findings from the files and follow-ups of the selected patients. Data was processed and analyzed in Statistical Package for Social Sciences (SPSS) version 20.0. Results: The age of the subjects ranged from 18 to 39 years, with a maximum number of subjects in the age category 31 to 35 years. BMI was significantly associated with number of follicles retrieved and clinical pregnancy rate (P= 0.001). Conclusion: Normal BMI has positive impact both on follicular response in controlled ovarian stimulation (COS) and clinical pregnancy rates in women undergoing IVF/ICSI treatment.


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