scholarly journals Significance of the spatial reconstruction based on mathematical modeling in the surgical treatment of giant intracranial aneurysms

2006 ◽  
Vol 63 (1) ◽  
pp. 65-68 ◽  
Author(s):  
Igor Nikolic ◽  
Mirjana Nagulic ◽  
Vaso Antunovic
Keyword(s):  
Blood Vessels ◽  
Intracranial Aneurysms ◽  
Giant Aneurysm ◽  
Diagnostic Procedures ◽  
Left Middle Cerebral Artery ◽  
Conventional Angiography ◽  
3 Dimensional ◽  
Giant Intracranial Aneurysms ◽  
Spatial Reconstruction ◽  
Dimensional Reconstruction

Background. The use of computer models for the 3- dimensional reconstruction could be a reliable method to overcome technical imperfections of diagnostic procedures for the microsurgical operation of giant intracranial aneurysms. Case report. We presented a case of successfully operated 52-year-old woman with giant intracranial aneurysm, in which the computer 3-dimensional reconstruction of blood vessels and the aneurysmal neck had been decisive for making the diagnosis. The model for 3- dimensional reconstruction of blood vessels was based on the two 2-dimensional projections of the conventional angiography. Standard neuroradiologic diagnostic procedures showed a giant aneurysm on the left middle cerebral artery, but the conventional subtraction and CT angiography did not reveal enough information. By the use of a personal computer, we performed a 3-dimensional spatial reconstruction of the left carotid artery to visualize the neck of aneurysm and its supplying blood vessels. Conclusion. The 3-dimensional spatial reconstruction of the cerebral vessels of a giant aneurysm based on the conventional angiography could be useful for planning the surgical procedure.

Space reconstruction of the aneurysms of the vertebrobasilary confluence based on conventional angiography: Our experience

2008 ◽  
Vol 55 (2) ◽  
pp. 75-78
Author(s):  
I.M. Nikolic ◽  
M.Lj. Rakic ◽  
E.E. Slavik ◽  
G.M. Tasic ◽  
B.M. Djurovic ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Diagnostic Procedures ◽  
Conventional Angiography ◽  
Two Dimensional Image ◽  
Diagnostic Protocol ◽  
Clinical Center ◽  
Golden Standard ◽  
Preoperative Diagnostic ◽  
Third Dimension ◽  
Initial Results

Besides current development of the new diagnostic procedures conventional angiography still represents the golden standard in the diagnosing of intracranial aneurysms. Since it gives a two-dimensional image if the presentation of the third dimension is wanted it is necessary to apply appropriate algorithm structures and computers. In this study we show our experience in the application of space reconstruction of blood vessels and aneurysms of the vertebrobasilary confluence in 6 patients operated at the Institute for Neurosurgery, Clinical Center of Serbia. Intraoperative finding in all patients matched the finding that we got by space reconstruction of the blood vessels, which was possible to observe from different angles. Postoperative course in all patients was satisfying. Upon discharge the patients were without rough lateralization of the pyramidal system. Our initial results and their practical agreement with the interoperative finding give us right to recommend this method as the standard for the preoperative diagnostic protocol.

scholarly journals Ruptured giant intracranial aneurysms. Part I. A study of rebleeding

1998 ◽  
Vol 4 (1) ◽  
pp. E1 ◽  
Author(s):  
Vini G. Khurana ◽  
David G. Piepgras ◽  
Jack P. Whisnant
Keyword(s):  
Cerebrospinal Fluid ◽  
Mayo Clinic ◽  
Intracranial Aneurysms ◽  
Management Strategies ◽  
Giant Aneurysm ◽  
Cumulative Frequency ◽  
Cerebrospinal Fluid Drainage ◽  
Giant Aneurysms ◽  
Giant Intracranial Aneurysms ◽  
Intracranial Circulation

Object The present study was conducted to estimate the frequency and timing of rebleeding after initial subarachnoid hemorrhage (SAH) from ruptured giant aneurysms. Methods The authors reviewed records of 109 patients who suffered an initial SAH from a giant aneurysm and were treated at the Mayo Clinic between 1973 and 1996. They represented 25% of patients with giant intracranial aneurysms seen at this institution during that 23-year period. Seven of the patients were residents of Rochester, Minnesota, and the rest were referred from other institutions. The aneurysms ranged from 25 to 60 mm in diameter, and 74% were located on arteries of the anterior intracranial circulation. The cumulative frequency of rebleeding at 14 days after admission was 18.4%. Cerebrospinal fluid drainage, cerebral angiography, and delayed aneurysm recurrence were implicated in rebleeding in some of the patients. Rebleeding was not precluded by intraaneurysm thrombosis. Among those who suffered recurrent SAH at the Mayo Clinic, 33% died in the hospital. Conclusions Rebleeding from giant aneurysms occurs at a rate comparable to that associated with smaller aneurysms, a finding that should be considered in management strategies.

scholarly journals Computer-assisted spatial reconstruction of cerebral blood vessels and intracranial aneurysms

2006 ◽  
Vol 59 (1-2) ◽  
pp. 24-27 ◽  
Author(s):  
Igor Nikolic
Keyword(s):  
Three Dimensional ◽  
Cerebral Aneurysms ◽  
Carotid Bifurcation ◽  
Computer Assisted ◽  
Three Dimensional Reconstruction ◽  
Conventional Angiography ◽  
Spatial Reconstruction ◽  
Dimensional Reconstruction ◽  
Vascular Structures ◽  
Carotid Aneurysms

Introduction. Today, many medical procedures are based on image analysis with the aim of providing accurate diagnosis and optimal treatment. The goal of this report was to present clinical implications of computer-assisted geometric design of carotid aneurysms. Material and methods. In this study, the three-dimensional reconstruction was based on the approximation power of the parametric spline function, which achieves interpolation and surface fitting of the arterial information obtained by conventional angiography. Two views of conventional angiograms (anterioposterior and lateral views) were used with a personal computer and commercial software. Results. This method of three-dimensional generated images was applied in 45 cases of cerebral aneurysms in carotid bifurcation. 3D reconstructions were made in approximately 20 minutes. They contributed to assessing vascular structures, and it was possible to rotate the three-dimensional image in different angles. Conclusion. Three-dimensional reconstruction of cerebral vessels is very useful for discussing surgical strategies preoperatively. Furthermore, it could also be used in endovascular procedures. .

Ruptured giant intracranial aneurysms. Part I. A study of rebleeding

1998 ◽  
Vol 88 (3) ◽  
pp. 425-429 ◽  
Author(s):  
Vini G. Khurana ◽  
David G. Piepgras ◽  
Jack P. Whisnant
Keyword(s):  
Mayo Clinic ◽  
Intracranial Aneurysms ◽  
Management Strategies ◽  
Giant Aneurysm ◽  
Cumulative Frequency ◽  
Content Type ◽  
Giant Aneurysms ◽  
Giant Intracranial Aneurysms ◽  
Intracranial Circulation ◽  
Fine Print

Object. The present study was conducted to estimate the frequency and timing of rebleeding after initial subarachnoid hemorrhage (SAH) from ruptured giant aneurysms. Methods. The authors reviewed records of 109 patients who suffered an initial SAH from a giant aneurysm and were treated at the Mayo Clinic between 1973 and 1996. They represented 25% of patients with giant intracranial aneurysms seen at this institution during that 23-year period. Seven of the patients were residents of Rochester, Minnesota, and the rest were referred from other institutions. The aneurysms ranged from 25 to 60 mm in diameter, and 74% were located on arteries of the anterior intracranial circulation. The cumulative frequency of rebleeding at 14 days after admission was 18.4%. Cerebrospinal fluid drainage, cerebral angiography, and delayed aneurysm recurrence were implicated in rebleeding in some of the patients. Rebleeding was not precluded by intraaneurysm thrombosis. Among those who suffered recurrent SAH at the Mayo Clinic, 33% died in the hospital. Conclusions. Rebleeding from giant aneurysms occurs at a rate comparable to that associated with smaller aneurysms, a finding that should be considered in management strategies.

scholarly journals Computerized Reconstruction of Pulpal Blood Vessels Examined under Confocal Microscope

2015 ◽  
Vol 19 (1) ◽  
pp. 43-49
Author(s):  
Anna Digka ◽  
Kleoniki Lyroudia ◽  
Lucie Kubinova ◽  
Georgia Karayannopoulou ◽  
Ioannis Marras ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Cross Sections ◽  
Automatic Segmentation ◽  
Spatial Relationship ◽  
Confocal Microscope ◽  
Confocal Laser ◽  
Computer Assisted ◽  
3 Dimensional ◽  
Dimensional Reconstruction ◽  
And Function

SUMMARYThe purpose of this study was the evaluation of 3 different histological methods for studying pulpal blood vessels in combination with 2 types of confocal microscope and computer assisted 3-dimensional reconstruction. 10 human, healthy, free of restorations or caries teeth that were extracted for orthodontic reasons were used. From these teeth, the pulp tissues of 5 were removed, fixed in formalin solution, dehydrated and embedded in paraffin. Serial cross sections 5μm thick were taken from 3 of the above mentioned pulpal tissues and stained with CD34 according to the immunohistochemical ABC technique, while the rest 2 were stained with CD34 and Cy5 by means of immunofluorescence after serial cross sectioning of 10μm. 5 of the 10 teeth were fixed, decalcified, serial cross sectioned (30μm thickness) and stained with eosin. The physical sections were examined under 2 types of confocal laser microscope. Serial images were taken for each section, alignment of the images was followed and finally 3-dimensional reconstructions of the pulpal vessels were achieved.The combined use of immunofluorescence, confocal microscope and automatic segmentation proved to be a useful method for the detailed study of pulpal vasculature. The above method provides deep knowledge of the form and spatial relationship even of the smallest pulpal blood vessels with neighbouring structures like odontoblasts, which are essential for the fully understanding of their role and function within the dental pulp.

scholarly journals Assessing the quality of angiographic display of brain blood vessels aneurysms compared to intraoperative state

2013 ◽  
Vol 70 (12) ◽  
pp. 1117-1123 ◽  
Author(s):  
Igor Nikolic ◽  
Goran Tasic ◽  
Vladimir Jovanovic ◽  
Nikola Repac ◽  
Aleksandar Janicijevic ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Computed Tomographic Angiography ◽  
Conventional Angiography ◽  
Computed Tomographic ◽  
Advantages And Disadvantages ◽  
Spatial Reconstruction ◽  
Clinical Center ◽  
Preoperative Diagnostic ◽  
Clear Visibility ◽  
Tomographic Angiography

Background/Aim. Aneurysms in brain blood vessels are expanding bags composed of a neck, body and fundus. Clear visibility of the neck, the position of the aneurysm and surrounding structures are necessary for a proper choice of methods for excluding the aneurysm from the circulation. The aim of this study was to evaluate the reliability of spatial reconstruction of blood vessels of the brain based on the original software for 3D reconstruction of the equipment manufacturer and a personal computer model developed earlier in the Clinic for Neurosurgery, Clinical Center of Serbia, Belgrade, compared to intraoperative identification of these aneurysms. Methods. This study included 137 patients of both sexes. The presence of an aneurysm was verified by angiographic methods [computed tomographic angiography (CTA), multislice computed tomography angiography (MSCTA), magnetic resonance imaging angiography (MRA), or digital subtraction angiography (DSA)]. Results. The quality score (0 to 5) for CTA was 3.180 ? 0.961, MSCTA 4.062 ? 0.928, and for DSA 4.588 ? 0.758 (p < 0.01). The results of this study favorite conventional angiography as the gold standard for diagnostic of intracranial aneurysms. Conclusion. The results of this study are consistent with current publications review and clearly recognize the advantages and disadvantages of diagnostic neuroradiological procedures, with DSA of brain blood vessels as a binding preoperative diagnostic procedure in cases in who it is not possible to clearly visualize the supporting blood vessel and neck of the aneurysm by using the findings of CTA, MRA and MSCTA.

Solitaire FR Stent as an Adjunctive Tool for Pipeline Stent Deployment in the Treatment of Giant Intracranial Aneurysms

2012 ◽  
Vol 72 (2) ◽  
pp. ons241-ons244
Author(s):  
Frédéric Clarençon ◽  
Gerald Wyse ◽  
Noel Fanning ◽  
Federico Di Maria ◽  
André Gaston ◽  
...  
Keyword(s):  
Intracranial Aneurysms ◽  
Giant Aneurysm ◽  
Parent Artery ◽  
Stent Deployment ◽  
Pipeline Embolization Device ◽  
Unruptured Aneurysms ◽  
Giant Intracranial Aneurysms ◽  
Solitaire Fr ◽  
Pipeline Stent ◽  
Flow Diverting Stent

Abstract BACKGROUND AND IMPORTANCE: The use of flow-diverting stents has gained acceptance during the past few years for the treatment of numerous intracranial aneurysms, especially large or giant ones. However, successful catheterization of the distal parent artery in giant intracranial aneurysms with a microcatheter can be extremely challenging. Forming a microcatheter loop in the aneurysm sac can aid distal catheterization. CLINICAL PRESENTATION: We report the use of a Solitaire FR stent as an adjunctive tool in the successful treatment of 2 giant intracranial unruptured aneurysms with a Pipeline Embolization Device. After having formed a loop inside the aneurysm sac, the microcatheter was anchored distally by a Solitaire FR stent. With the Solitaire FR device opened, the loop in the giant aneurysm sac was completely reduced without loss of the microcatheter position in the distal parent artery. A Pipeline Embolization Device could be delivered in both cases without any difficulty. There were no complications. CONCLUSION: The technique described results in ideal microcatheter alignment with a secure distal position before deployment of a flow-diverting stent.

Three-Dimensional Reconstruction Using Stereo Pairs from Serial Thick Sections

1977 ◽  
Vol 35 ◽  
pp. 562-563
Author(s):  
Robert Glaeser ◽  
Thomas Bauer ◽  
David Grano
Keyword(s):  
Three Dimensional ◽  
Dimensional Structure ◽  
Serial Sections ◽  
Thin Sections ◽  
3 Dimensional ◽  
Transmission Electron ◽  
Freeze Dried ◽  
Dimensional Reconstruction ◽  
Stereo Imagery ◽  
Whole Mounts

In transmission electron microscopy, the 3-dimensional structure of an object is usually obtained in one of two ways. For objects which can be included in one specimen, as for example with elements included in freeze- dried whole mounts and examined with a high voltage microscope, stereo pairs can be obtained which exhibit the 3-D structure of the element. For objects which can not be included in one specimen, the 3-D shape is obtained by reconstruction from serial sections. However, without stereo imagery, only detail which remains constant within the thickness of the section can be used in the reconstruction; consequently, the choice is between a low resolution reconstruction using a few thick sections and a better resolution reconstruction using many thin sections, generally a tedious chore. This paper describes an approach to 3-D reconstruction which uses stereo images of serial thick sections to reconstruct an object including detail which changes within the depth of an individual thick section.

Structural preservation and absolute contrast of catalase crystal sections prepared with tannic acid

1983 ◽  
Vol 41 ◽  
pp. 448-449
Author(s):  
C.W. Akey ◽  
M. Szalay ◽  
S.J. Edelstein
Keyword(s):  
Tannic Acid ◽  
Beef Heart ◽  
X Rays ◽  
Screw Axis ◽  
General Applicability ◽  
Thin Sections ◽  
Beef Liver ◽  
3 Dimensional ◽  
Dimensional Reconstruction ◽  
Structural Preservation

Three methods of obtaining 20 Å resolution in sectioned protein crystals have recently been described. They include tannic acid fixation, low temperature embedding and grid sectioning. To be useful for 3-dimensional reconstruction thin sections must possess suitable resolution, structural fidelity and a known contrast. Tannic acid fixation appears to satisfy the above criteria based on studies of crystals of Pseudomonas cytochrome oxidase, orthorhombic beef liver catalase and beef heart F1-ATPase. In order to develop methods with general applicability, we have concentrated our efforts on a trigonal modification of catalase which routinely demonstrated a resolution of 40 Å. The catalase system is particularly useful since a comparison with the structure recently solved with x-rays will permit evaluation of the accuracy of 3-D reconstructions of sectioned crystals.Initially, we re-evaluated the packing of trigonal catalase crystals studied by Longley. Images of the (001) plane are of particular interest since they give a projection down the 31-screw axis in space group P3121. Images obtained by the method of Longley or by tannic acid fixation are negatively contrasted since control experiments with orthorhombic catalase plates yield negatively stained specimens with conditions used for the larger trigonal crystals.

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