Binary structure functions with dependent components

1990 ◽  
Vol 22 (3) ◽  
pp. 627-640 ◽  
Author(s):  
Nader Ebrahimi

In this paper we attempt to develop an axiomatic theory of binary structure functions with dependent components. This is an important problem, hitherto largely ignored. The concept ofcoherent structure in probabilityis introduced and studied. The relationship to the classicalcoherent structureis discussed. In the new concept the relevancy is defined through reliability of the system, while in the classical concept it is defined through the structure function.


1990 ◽  
Vol 22 (03) ◽  
pp. 627-640 ◽  
Author(s):  
Nader Ebrahimi

In this paper we attempt to develop an axiomatic theory of binary structure functions with dependent components. This is an important problem, hitherto largely ignored. The concept ofcoherent structure in probabilityis introduced and studied. The relationship to the classicalcoherent structureis discussed. In the new concept the relevancy is defined through reliability of the system, while in the classical concept it is defined through the structure function.



2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Zijin Gu ◽  
Keith Wakefield Jamison ◽  
Mert Rory Sabuncu ◽  
Amy Kuceyeski

AbstractWhite matter structural connections are likely to support flow of functional activation or functional connectivity. While the relationship between structural and functional connectivity profiles, here called SC-FC coupling, has been studied on a whole-brain, global level, few studies have investigated this relationship at a regional scale. Here we quantify regional SC-FC coupling in healthy young adults using diffusion-weighted MRI and resting-state functional MRI data from the Human Connectome Project and study how SC-FC coupling may be heritable and varies between individuals. We show that regional SC-FC coupling strength varies widely across brain regions, but was strongest in highly structurally connected visual and subcortical areas. We also show interindividual regional differences based on age, sex and composite cognitive scores, and that SC-FC coupling was highly heritable within certain networks. These results suggest regional structure-function coupling is an idiosyncratic feature of brain organisation that may be influenced by genetic factors.



2017 ◽  
Vol 14 (135) ◽  
pp. 20170484 ◽  
Author(s):  
Matthew D. B. Jackson ◽  
Salva Duran-Nebreda ◽  
George W. Bassel

Multicellularity and cellular cooperation confer novel functions on organs following a structure–function relationship. How regulated cell migration, division and differentiation events generate cellular arrangements has been investigated, providing insight into the regulation of genetically encoded patterning processes. Much less is known about the higher-order properties of cellular organization within organs, and how their functional coordination through global spatial relations shape and constrain organ function. Key questions to be addressed include: why are cells organized in the way they are? What is the significance of the patterns of cellular organization selected for by evolution? What other configurations are possible? These may be addressed through a combination of global cellular interaction mapping and network science to uncover the relationship between organ structure and function. Using this approach, global cellular organization can be discretized and analysed, providing a quantitative framework to explore developmental processes. Each of the local and global properties of integrated multicellular systems can be analysed and compared across different tissues and models in discrete terms. Advances in high-resolution microscopy and image analysis continue to make cellular interaction mapping possible in an increasing variety of biological systems and tissues, broadening the further potential application of this approach. Understanding the higher-order properties of complex cellular assemblies provides the opportunity to explore the evolution and constraints of cell organization, establishing structure–function relationships that can guide future organ design.



2000 ◽  
Vol 15 (supp01b) ◽  
pp. 467-494 ◽  
Author(s):  
MAX KLEIN

This report presents the latest results on structure functions, as available at the Lepton-Photon Symposium 1999. It focuses on three experimental areas: new structure function measurements, in particular from HERA at low x and high Q2; results on light and heavy flavor densities; and determinations of the gluon distribution and of αs. As the talk was delivered at a historic moment and place, a few remarks were added recalling the exciting past and looking into the promising future of deep inelastic scattering (DIS).



2014 ◽  
Vol 17 (4) ◽  
pp. 307-311 ◽  
Author(s):  
Yafei Luo ◽  
Tomoyuki Hatakeyama ◽  
Shinji Nakagawa ◽  
Masaru Ishizuka


2020 ◽  
Author(s):  
Han-Ha Chai ◽  
Young Ran Kim ◽  
Jun-Sang Ham ◽  
Tae-Hun Kim ◽  
Dajeong Lim

Abstract Background: The OppA receptor as a ATP-binding cassette (ABC) transporter plays key roles in protecting host organism and transport nutrients across the intestine by the oligopeptide transporter from symbiotic bacteria directs maturation of the host immune system. Among lactic acid bacteria, Bifidobacterium longum KACC91563, isolated from fecal samples of healthy Korean neonates, has the capability to alleviate food allergy effects. The extracellular OppA receptor from gram-positive Bifidobacterium longum KACC91563 translocate nutrients-peptides from the outside environment of intestinal tract to the inside of the symbiotic cell, as a peptide importer. Hence, it was attempting to explicate the relationship between the substrate’s specificity from the OppA importer and the probiotic effects of B. logum KACC91563 in the host intestine. The probiotic effects of B. logum KACC91563 were attributed to the enhancement of the epithelial barrier by several different strain sepcific ways to prevent the strong adhesion of pathogens. The specialized structure-function relationship from the OppA importer could provide the abstract of substrate specificity into unique immunological properties of that the host organism.Results: In the study, we characterized the extracellular OppA importer from B. longum KACC91563 of intestinal microbiome by various protein structure-based modelings in silico. Structural characterization by conserved 5 patches and 4 functional motifs from specific trace residues of the OppA importer. The hydrate surface of the binding site had been decipted by specific trace residues of the OppA that trace residues of Thr58, Lys185, Trp443, and Tyr447, which were characterized in highly exposed hydrophobic binding pocket by its aggregation prones. Therefore, the spatial aggregation propensity in the binding site of the extracellular OppA importer plays a vital role in the specific interaction determinant for peptide binding. In addition, alanine mutation energy values allowed for the virtual determination of the relationships between the energy effects of the peptide binding site mutation on the transporter structural stability, the peptide binding affinity, and the transporter-related peptide substrate selectivity from OppA importer. In particular, distinctive seven pharmacophoric features comprised of two H-bonding donor(P1), three H-bonding acceptor(P8), and two hydrophobic points (P5 and P8) matched the the OppA receptor-peptide ligand interactions within their binding pocket structure. There are distinct interactions to fix the positions of the N(P1) and C(P8) termini of the complex of OppA-peptide from B. longum KACC91563 such as side chain-specific interactions with the OppA, compared to that of the Lactococcus latis (L. lactics) OppA.Conclusions: The specialized structure-function relationship from the OppA import could provide the abstract of substrate specificity into unique immunological properties of the host organism by stucutre-based molecular modeling. In the current study, we attempted explication of the relationship between the substrate’s specificity from the OppA importer and the probiotic effects of B. longum KACC91563 in the host intestine based on the structure-function perspectives of the OppA importer. Moreover, functional characterization of solute-binding proteins (such as 15 cell wall proteins and 20 extracellular proteins) on the B. longum KACC91563 genome will lead to insight of key switch for substate’s metabolism into reprogramming immune responses in the host intestine.



1986 ◽  
Vol 67 (2) ◽  
pp. 177-185 ◽  
Author(s):  
Lauren L. Morone

Data collected from aircraft equipped with AIDS (Aircraft Integrated Data System) instrumentation during the Global Weather Experiment year of 1979 are used to estimate the observational error of winds at flight level from this and other aircraft automated wind-reporting systems. Structure functions are computed from reports that are paired using specific criteria. The value of this function extrapolated to zero separation distance is an estimate of twice the random measurement-error variance of the AIDS-measured winds. Component-wind errors computed in this way range from 2.1 to 3.1 m · s−1 for the two months of data examined, January and August 1979. Observational error, specified in optimum-interpolation analyses to allow the analysis to distinguish among observations of differing quality, is composed of both measurement error and the error of unrepresentativeness. The latter type of error is a function of the resolvable scale of the analysis-prediction system. The structure function, which measures the variability of a field as a function of separation distance, includes both of these types of error. If the resolvable scale of an analysis procedure is known, an estimate of the observational error can be computed from the structure function at that particular distance. An observational error of 5.3 m · s−1 was computed for the u and v wind components for a sample resolvable scale of 300 km. The errors computed from the structure functions are compared to colocation statistics from radiosondes. The errors associated with automated wind reports are found to compare favorably with those estimated for radiosonde winds at that level.



2012 ◽  
Vol 184-185 ◽  
pp. 1080-1083
Author(s):  
Jian Ling Yue ◽  
Wei Shi ◽  
Ge Yang Li

A series of VC/TiN nano-multilayer films with various TiN layer thicknesses were synthesized by magnetron sputtering method. The relationship between the modulation structure and superhardness effect of the multilayer films were investigated. The results reveal that TiN below a critical layer thickness grows coherently with VC layers in multilayers. Correspondingly, the hardness and elastic modulus of the multilayers increase significantly. The maximum hardness and modulus achieved in these multilayers is 40.7GPa and 328GPa.With further increase in the TiN layer thickness, coherent structure of multilayers are destroyed, resulting in a remarkable decrease of hardness and modulus. The superhardness effect of multilayers is related to the three directional strains generated from the coherent structure.



2018 ◽  
Vol 33 (08) ◽  
pp. 1850046 ◽  
Author(s):  
D. K. Choudhury ◽  
Baishali Saikia

Froissart bound implies that the total proton–proton cross-section (or equivalently proton structure function) cannot rise faster than [Formula: see text]. Compatibility of such behavior with the notion of self-similarity in proton structure function was suggested by us sometime back. In the present work, we generalize and improve it further by considering more recent self-similarity based models of proton structure functions and compare with recent data as well as with the model of Block, Durand, Ha and McKay.



2007 ◽  
Vol 50 (13) ◽  
pp. 1238-1245 ◽  
Author(s):  
Anil Verma ◽  
Nagesh S. Anavekar ◽  
Alessandra Meris ◽  
Jens Jakob Thune ◽  
J. Malcolm O. Arnold ◽  
...  


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