Comments on the Review of “The Effigy Mound Culture of Wisconsin”

1958 ◽  
Vol 24 (2) ◽  
pp. 191-192
Author(s):  
W. C. McKern
Keyword(s):  
American Antiquity ◽  
General Status ◽  
Treat Ment ◽  
Effigy Mound

David Baerreis’ review of The Effigy Mound Culture of Wisconsin, by Chandler Rowe (American Antiquity, Vol. 23, No. 3, pp. 320–1), includes certain criticisms of methods and procedures underlying the author’s treat’ ment of his subject that raise important questions as to the general status of archaeological concept and methodology.For example, commenting on Rowe’s rejection of the early guess that effigy mound shapes represent clan symbols, Baerreis appears to argue that at some time, some tribe or tribes could possibly have possessed totemic patterns that might account for effigy mound shapes.

A Multicenter Study of Recombinant Factor VIII (RecombinateTM) in Previously Treated Patients with Hemophilia A

1997 ◽  
Vol 77 (04) ◽  
pp. 660-667 ◽  
Author(s):  
G C White ◽  
S Courter ◽  
G L Bray ◽  
M Lee ◽  
E D Gomperts ◽  
...  
Keyword(s):  
Hemophilia A ◽  
Recombinant Dna ◽  
Home Treatment ◽  
Pharmacokinetic Parameters ◽  
Pharmacokinetic Studies ◽  
Open Label ◽  
Treat Ment ◽  
Previously Treated Patients ◽  
Bleeding Episodes

SummaryA prospective, open-label multicenter investigation has been conducted to compare pharmacokinetic parameters of recombinant DNA-derived FVIII (rFVIII) and plasma-derived FVIII concentrate (pdFVIII) and to assess safety and efficacy of long-term home-treat- ment with rFVIII for subjects with hemophilia A. Following comparative in vivo pharmacokinetic studies, 69 patients with severe (n = 67) or moderate (n = 2) hemophilia A commenced a program of home treatment using rFVIII exclusively for prophylaxis and treatment of all bleeding episodes for a period of 1.0 to 5.7 years (median 3.7 years). The mean in vivo half-lives of rFVIII and pdFVIII were both 14.7 h. In vivo incremental recoveries at baseline were 2.40%/IU/kg and 2.47%/IU/kg, respectively (p = 0.59). The response to home treatment with rFVIII was categorized as good or excellent in 3,195 (91.2%) of 3,481 evaluated bleeding episodes. Thirteen patients received rFVIII for prophylaxis for twenty-four surgical procedures. In all cases, hemostasis was excellent. Adverse reactions were observed in only 13 of 13,591 (0.096%) infusions of rFVIII; none was serious. No patient developed an inhibitor to r FVIII.

A Questionnaire Survey on General Status and Opinions about Clinical Mass Spectrometric Analysis in Korea (2018)

2019 ◽  
Vol 9 (3) ◽  
pp. 161
Author(s):  
Sung-Eun Cho ◽  
Hyojin Chae ◽  
Hyung-Doo Park ◽  
Sail Chun ◽  
Yong-Wha Lee ◽  
...  
Keyword(s):  
Questionnaire Survey ◽  
Mass Spectrometric ◽  
Mass Spectrometric Analysis ◽  
Spectrometric Analysis ◽  
General Status

MODERN ASPECTS OF TREATMENT CHRONIC ENDOMETRITIS

2020 ◽  
pp. 58-61
Author(s):  
Shelemekh K.E. ◽  
Petrov Yu.A. ◽  
Arndt I.G. ◽  
Evdokimova E.P. ◽  
Chernavsky V.V.
Keyword(s):  
Chronic Inflammation ◽  
Postpartum Period ◽  
Scientific Literature ◽  
Local Treatment ◽  
Symptomatic Treatment ◽  
Chronic Endometritis ◽  
Disease Complex ◽  
Treat Ment ◽  
Long Term Consequences

The analysis of the data of modern scientific literature containing information on topical issues in the treat-ment of chronic endometritis as one of the most acute, frequently encountered problems of modern gynecol-ogy is carried out. This disease today requires special attention of doctors and scientists due to the erased course of the disease, complex diagnostics and multi-faceted treatment. Chronic inflammation affects men-strual function, fertility of women, is often a complica-tion of pregnancy, childbirth, the postpartum period, and can also cause infertility and early loss, which actualizes the topic of timely and individually selected treatment for patients diagnosed with chronic endo-metritis. Treatment should be aimed at relieving clini-cal symptoms, eradicating the pathogen and combat-ing adverse long-term consequences. Today, many approaches to treatment are known, but it is worth choosing the most effective and promising ones. In addition to etiotropic and symptomatic treatment, attention should be paid to restoring the morphofunc-tional potential of the endometrium with the help of physiotherapy. An important advantage of such com-plexes is the possibility of intracavitary effects that increase the effectiveness of treatment due to local treatment.

Thiazole-Based Chalcone Derivatives as Potential Anti-inflammatory Agents: Biological Evaluation and Molecular Modelling

2020 ◽  
Vol 21 ◽  
Author(s):  
Michelyn Haroun ◽  
Christopher Tratrat ◽  
Evangelia Tsolaki ◽  
Anthi Petrou ◽  
Antonis Gavalas ◽  
...  
Keyword(s):  
Aromatic Aldehyde ◽  
Molecular Modelling ◽  
Biological Evaluation ◽  
Inflammatory Activity ◽  
Paw Edema ◽  
Chalcone Derivatives ◽  
Treat Ment ◽  
Anti Inflammatory

Background.: Inflammation is a multifactorial process reflecting response of the organismto various stimuli and is associated to a number of disorders such as arthritis, asthma and psoriasis, which require long-lasting or repeated treat-ment. Objective.: The aim of this paper is to evaluate the anti-inflammatory activity of previous synthesized thiazole-based chal-cone derivatives. Method.: Chalcones were synthesized via Cliazen-Schmidt condensation1-(4-methyl-2-alkylamino)thiazol-5-yl) ethanone with corresponding aromatic aldehyde. For the evaluation of possible anti-inflammatory activity carrageneen mouse paw edema was used. Results.: Eight out of thirteen tested chalcones showed anti-inflammatory activity in range of 51-55%. Prediction of toxicity revealed that these compounds are not toxic. Conclusion.: In general, it can be concluded that these compounds can be used for further modifications in order to develop more active and safe agents.

scholarly journals Low-dose sublingual immunotherapy compared to subcutaneous immunotherapy and conventional therapy in childhood asthma

2016 ◽  
Vol 44 (6) ◽  
pp. 243
Author(s):  
Ariyanto Harsono
Keyword(s):  
Childhood Asthma ◽  
Low Dose ◽  
Sublingual Immunotherapy ◽  
Disease Onset ◽  
Ethics Committee ◽  
Subcutaneous Immunotherapy ◽  
Control Group ◽  
High Dose ◽  
Treat Ment ◽  
Group A

Background Evidence begin to accumulate that high-dose sub-lingual immunotherapy (SLIT) is as effective as subcutaneousimmunotherapy (SIT) in the treatment of childhood asthma.Since the capacity of sublingual area is similar whether the doseis high or low, the efficacy of low dose may be important to bestudied.Objective To investigate the efficacy of low-dose sublingual im-munotherapy in the treatment of childhood asthma.Methods Parents signed informed consent prior to enrollment,after having received information about the study. Patients weremoderate asthma aged 6-14 years with disease onset of lessthan 2 years before the commencement of the study and peakexpiratory flow rate (PEFR) variability of more than 15%. Pa-tients were randomly allocated into group A, B, and C whoreceived subcutaneous immunotherapy, low-dose sublingualimmunotherapy, and conventional asthma therapy, respectively.Randomization was stratified into two strata according to agei.e., 6-11 years or 11-14 years. Patients of each stratum wererandomized in block of three for each group. At the end of threemonths, lung function tests were repeated. The primary outcomewas PEFR variability at the end of the study. The study wasapproved by the Ethics Committee of Soetomo HospitalSurabaya.Results Distribution of variants as represented by sex, age,eosinophil count, and total IgE concentration were normal inthe three groups. PEFR variability decreased significantly from16.97+0.81 to 8.50+5.08 and 17.0+0.87 to 8.40+4.72 in groupreceiving SIT and SLIT, respectively (p<0.05), but decreasednot significantly from 17.00+0.83 to 10.82+0.5.41 in control group(p>0.05).Conclusion Low-dose SLIT is as efficacious as SIT in the treat-ment of moderate asthma in children

The general status of rare disorders

2021 ◽  
Vol 5 (3-4) ◽  
pp. 97-98
Author(s):  
Alan K. Percy ◽  
Rashmi Gopal-Srivastava
Keyword(s):  
Rare Disorders ◽  
General Status

State-of-the-Art Review : Management of Patients Who Require Invasive Procedures Immediately Following Thrombolytic Therapy

1996 ◽  
Vol 2 (3) ◽  
pp. 158-163
Author(s):  
Sophie M. Lanzkron ◽  
William R. Bell
Keyword(s):  
Thrombolytic Therapy ◽  
State Of The Art ◽  
Coronary Bypass ◽  
Bleeding Complications ◽  
Invasive Procedures ◽  
Antifibrinolytic Agents ◽  
Treat Ment ◽  
Review Management ◽  
Coagulation Proteins ◽  
Infarct Related Artery

In recent years the use of thrombolytic ther apy has been demonstrated to be valuable in the treat ment of patients with acute myocardial infarction. Often, because of the frequency of reocclusion of the infarct- related artery, identification of a treatable vascular le sion, or, rarely, failure of thrombolytic therapy, patients will require more invasive procedures to prevent further ischemic injury to the myocardium. These procedures in clude anything from cardiac catheterization to emergency coronary bypass surgery. The perioperative evaluation and management of patients who have recently received thrombolytic therapy requires an understanding of the changes in coagulation proteins that occur with the use of these therapeutic agents. The appropriate understanding and use of antifibrinolytic agents and blood products will allow for these procedures to be performed safely with a minimum of bleeding complications.

Sign in / Sign up

Export Citation Format

Share Document