Cost-Effective Eradication of an Outbreak of Methicillin-Resistant Staphylococcus aureus in a Community Teaching Hospital

1988 ◽  
Vol 9 (6) ◽  
pp. 255-260 ◽  
Author(s):  
Nalini Rao ◽  
Sharon Jacobs ◽  
Linda Joyce
1988 ◽  
Vol 9 (6) ◽  
pp. 255-260 ◽  
Author(s):  
Nalini Rao ◽  
Sharon Jacobs ◽  
Linda Joyce

AbstractDuring an eight-month period, 25 hospitalized patients became infected or colonized with methicillin-resistant Staphylococcus aureus (MRSA) in a 464-bed acute care, medical-surgical teaching hospital. There were only five cases during the eight months prior to the outbreak period (P < 0.0001). Initial measures, including category-specific isolation and education, did not limit the spread of the outbreak of a strain of MRSA. This prompted institution of additional measures including (1) strict isolation of all infected and colonized cases; (2) prospective microbiological surveillance to detect additional cases; (3) multiple site cultures of identified cases to determine the extent of colonization; (4) employee and environment surveillance; (5) antibiotic decolonization of patients and employees; and (6) educational efforts. The highest number of personnel carriers were noted in one of the critical care units where most of the cases occurred. The decolonization protocol was 100% effective for personnel carriers. The incidence of nosocomial cases of MRSA fell to zero in the five months following the implementation of the strategy. The cost of the entire eradication process was approximately half that of treating a single MRSA bacteremia.


2019 ◽  
Vol 16 (2) ◽  
pp. 01-08
Author(s):  
Abubakar Adamu ◽  
Hamman Ibrahim Garandawa ◽  
AbZailani Sambo B ◽  
Mohammad Y ◽  
Aliyu Mohammad Kodiya ◽  
...  

1984 ◽  
Vol 5 (1) ◽  
pp. 18-28 ◽  
Author(s):  
J.J. McNeil ◽  
A.D. Proudfoot ◽  
F.A. Tosolini ◽  
P. Morris ◽  
J.M. Booth ◽  
...  

1990 ◽  
Vol 11 (12) ◽  
pp. 639-642 ◽  
Author(s):  
John M. Boyce

AbstractIn the period 1975 to 1981, methicillin-resistant Staphylococcus aureus (MRSA) emerged as an important nosocomial pathogen in tertiary care centers in the United States. To determine if the prevalence of this organism has continued to increase, a questionnaire was sent to hospital epidemiologists in 360 acute care hospitals. A total of 256 (71%) of the 360 individuals responded. Overall, 97% (246/256) of responding hospitals reported having patients with MRSA in the period 1987 through 1989. Respondents in 217 hospitals provided estimates of the number of cases seen in 1987, 1988 and 1989. The percentage of respondents reporting one or more patients with MRSA increased from 88% in 1987 to 96.3% in 1989 (p = .0008). The percent of respondents reporting large numbers (≥50) of cases per year increased from 18% in 1987 to 32% in 1989 (p = .0006). Increasing frequency of large outbreaks was observed in community, community-teaching, federal, municipal and university hospitals.


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