Long-term follow-up of camouflage effects following resin infiltration of post orthodontic white-spot lesions in vivo

ABSTRACT Objectives: To reassess the long-term camouflage effects of resin infiltration (Icon, DMG, Hamburg, Germany) of white spot lesions (WSL) and sound adjacent enamel (SAE) achieved in a previous trial. The null hypothesis was tested that there were no significantly different CIE-L*a*b*-ΔE-values between WSL and SAE areas of assessment after at least 24 months (T24) compared to those at baseline (T0). Materials and Methods: Of twenty subjects who received previous resin infiltration treatment of nteeth = 111 nonrestored, noncavitated postorthodontic WSL after multibracket treatment during a randomized controlled trial and were contacted 20 months after baseline, eight subjects (trial teeth nteeth = 40; m/f ratio 1/7; age range (mean; SD) 12–17 [15.25; 2.12] years); response rate: 40%) were available for follow-up after at least 24 months (T24). CIE-L*a*b* differences between summarized color and lightness values (ΔEWSL/SAE) of WSL and SAE were assessed using a spectrophotometer and compared to baseline data assessed prior to infiltration (T0), and those after 6 (T6), and 12 (T12) months using paired t tests at a significance level of α = 5%. Results: T24 assessments were performed after a mean 33.86 (SD: 8.64; Min: 24; Max: 45) months following T0. Mean (SD) ΔEWSL/SAE units of available teeth were 8.76 (5.33) at baseline; 5.5 (2.75) at T6; 5.2 (2.41) at T12; and 5.57 (2.6) at T24. Comparisons of T6, T12, and T24 with T0 yielded highly significant differences, whereas T6–T24 and T12–T24 differences were found to be not significant. Conclusions: Assimilation of infiltrated WSL to the color of adjacent enamel by resin infiltration is considered to be suitable for the long-term improvement in the esthetic appearance of postorthodontic WSL.

Download Full-text

Camouflage effects following resin infiltration of postorthodontic white-spot lesions in vivo: One-year follow-up

The Angle Orthodontist ◽

10.2319/050914-334.1 ◽

2015 ◽

Vol 85 (3) ◽

pp. 374-380 ◽

Cited By ~ 19

Author(s):

Amely Eckstein ◽

Hans-Joachim Helms ◽

Michael Knösel

Keyword(s):

White Spot ◽

White Spot Lesions ◽

Female Ratio ◽

Significance Level ◽

Resin Infiltration ◽

Male Female Ratio ◽

The Difference ◽

One Year

ABSTRACT Objective: To assess camouflage effects by concealment of postorthodontic white-spot lesions (WSLs) to sound adjacent enamel (SAE) achieved over 12 months with resin infiltration (Icon, DMG, Hamburg, Germany). Methods: Twenty subjects (trial teeth nteeth = 111) who had received resin infiltration treatment of noncavitated postorthodontic WSLs were contacted for a 1-year follow-up assessment of CIE-L*a*b* colors (T12). Color and lightness (CIE-L*a*b*) data for WSLs and SAE were compared to baseline data assessed before infiltration (T0) and those assessed after 6 months (T6), using a spectrophotometer. The target parameter was the difference between the summarized color and lightness values (ΔEWSL/SAE). Intergroup (WSL, SAE) and intertime comparisons (T0 vs T6, T12) were performed using paired t-tests at a significance level of α = 5%. Results: Nine subjects (trial teeth nteeth = 49; male/female ratio 5/4; age range 13–19 years) were available at T12. After the highly significant reduction of ΔEWSL/SAE discrepancies between T0 and T6, analysis of 12-month records revealed color and lightness discrepancy of WSL vs SAE that was significantly decreased compared with baseline, indicating an assimilation of WSL color to SAE appearance after infiltration, while an additional reduction of discrepancies between T6 and T12 was not significant. Conclusion: As color and lightness characteristics of the Icon infiltrant as well as the esthetic camouflage effects achieved by WSL infiltration were not altered significantly or clinically relevant after 12 months, the method of resin infiltration can be recommended for an enduring esthetic improvement of postorthodontic WSL. (Angle Orthod. 2015;85:374–380.)

Download Full-text

Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial

The Lancet ◽

10.1016/s0140-6736(21)00731-5 ◽

2021 ◽

Author(s):

Usha Menon ◽

Aleksandra Gentry-Maharaj ◽

Matthew Burnell ◽

Naveena Singh ◽

Andy Ryan ◽

...

Keyword(s):

Ovarian Cancer ◽

Cancer Screening ◽

Randomised Controlled Trial ◽

Controlled Trial ◽

Ovarian Cancer Screening ◽

Long Term Follow Up ◽

Randomised Controlled ◽

The Uk

Download Full-text

A LONG-TERM FOLLOW-UP STUDY OF A RANDOMIZED CONTROLLED TRIAL OF MOTHER-INFANT PSYCHOANALYTIC TREATMENT: OUTCOMES ON MOTHERS AND INTERACTIONS

Infant Mental Health Journal ◽

10.1002/imhj.21536 ◽

2015 ◽

Vol 36 (6) ◽

pp. 542-555 ◽

Cited By ~ 9

Author(s):

Majlis Winberg Salomonsson ◽

Kimmo Sorjonen ◽

Björn Salomonsson

Keyword(s):

Randomized Controlled Trial ◽

Treatment Outcomes ◽

Controlled Trial ◽

Follow Up Study ◽

Randomized Controlled ◽

Psychoanalytic Treatment ◽

Long Term Follow Up

Download Full-text

One Year Clinical Evaluation of White Spot Lesions with Newly Introduced Resin Modified Glass-Ionomer in Comparison to Resin Infiltration in Anterior Teeth: a split mouth randomized controlled clinical trial from Egypt

Brazilian Dental Science ◽

10.14295/bds.2021.v24i1.2063 ◽

2020 ◽

Vol 24 (1) ◽

pp. 13p

Author(s):

Shaimaa Mosutafa Rohym ◽

Asmaa Youssif Harhash ◽

Mohammed Farid Riad

Keyword(s):

Glass Ionomer Cement ◽

Resin Cement ◽

White Spot ◽

White Spot Lesions ◽

Glass Ionomer ◽

Resin Infiltration ◽

Anterior Teeth ◽

Diagnodent Pen ◽

Resin Modified Glass Ionomer

Objective: to compare the clinical performance of newly introduced resin modified glass ionomer varnish (Clinpro™ XT) versus resin infiltration in treatment of post-orthodontic white spot lesions. Material and Methods: Six participants (70 teeth) were enrolled with post-orthodontic white spot lesions. Randomization was performed according to patient selection for the sealed envelope containing which half will receive the control (resin infiltration (ICON, DMG) and the other will receive the intervention (resin modified glass-ionomer cement varnish (Clinpro™ XT, 3M)). Follow up was done after 1 day, 1 week, 1 month, and 3 months, 6 months and 12 months. The color was assessed by spectrophotometer while the degree of demineralization was measured by Diagnodent pen 2910. Patient satisfaction was assessed using (VAS) Visual analogue scale. Results: Regarding color change, significant improvement in lightness for ICON group, while Clinpro™ XT group, the change was insignificant. The demineralization data revealed significant decrease in demineralization with resin infiltration after immediate application. Clinpro™ XT showed also significant decrease after immediate assessment and significant increase in demineralization in 6 and 12 months. Conclusion: Resin infiltration can be considered more as an alternative treatment rather than fluoride varnish. Clinpro™ XTis considered as a preventive protocol, provided that renewal application is needed after 3 months. Keywords 3M Resin cement; Resin cements; Glass ionomer cements; Fluorides; Follow up studies; Glass ionomer.

Download Full-text

OT-Equator® Attachments Comparison for Retaining an Early Loaded Implant Overdenture on Two or Three Implants: 1 Year RCT Preliminary Data

Applied Sciences ◽

10.3390/app11188601 ◽

2021 ◽

Vol 11 (18) ◽

pp. 8601

Author(s):

Marco Tallarico ◽

Gabriele Cervino ◽

Marco Montanari ◽

Roberto Scrascia ◽

Emiliano Ferrari ◽

...

Keyword(s):

Controlled Trial ◽

Survival Rates ◽

Marginal Bone Loss ◽

Patient Centered ◽

Randomized Controlled ◽

Multicenter Randomized Controlled Trial ◽

Long Term Follow Up ◽

Implant Overdenture

The purpose of this multicenter randomized controlled trial was to compare the clinical, radiographic, and patient-centered outcomes of early loaded mandibular overdentures deliberately placed on two or three implants. The outcomes were: implant and prosthesis success and survival rates; biological and technical complications; marginal bone loss; patient satisfaction; and periodontal parameters. The results showed no differences between the groups in any of the outcomes analyzed. With the limitations of the present study, and looking at long-term follow-up, the gold standard of prosthetic rehabilitations with attachments, in agreement with the scientific community, should prefer two non-splinted implants.

Download Full-text

Fluoride varnish for white spot lesion prevention during orthodontic treatment: results of a randomized controlled trial 1 year after debonding

European Journal of Orthodontics ◽

10.1093/ejo/cjaa055 ◽

2020 ◽

Author(s):

Mikael Sonesson ◽

Anna Brechter ◽

Rolf Lindman ◽

Salem Abdulraheem ◽

Svante Twetman

Keyword(s):

Randomized Controlled Trial ◽

Placebo Group ◽

Orthodontic Treatment ◽

Controlled Trial ◽

White Spot ◽

Fluoride Varnish ◽

White Spot Lesion ◽

Randomized Controlled

Summary Background Topical fluorides are commonly recommended to prevent the development of white spot lesion (WSL) during treatment with fixed orthodontic appliances (FOAs), but the certainty of evidence is low, and long-term effects of fluoride preventive methods to reduce lesions seem to be rare. Objective To evaluate the long-term effectiveness of professional applications of a fluoride varnish containing 1.5% ammonium fluoride in preventing WSL development in adolescents undergoing multi-bracket orthodontic treatment. Subjects and methods We performed a randomized controlled trial in which 166 healthy adolescents (12–18 years) from three different clinics were enrolled and randomly allocated to a test or a placebo group. The randomization was performed by a computer program, generating sequence numbers in blocks of 15. The fluoride varnish or the non-fluoride placebo varnish was applied in a thin layer around the bracket base every sixth week during the course of the orthodontic treatment (mean duration 1.7 years). We scored the prevalence of WSL on the labial surfaces of the maxillary incisors, canines and premolars immediately after debonding (baseline) and approximately 1 year after debonding, from digital photos with aid of a four-step score. The examiners were not involved in the treatment of the patients and blinded for the group assignment. Results One hundred and forty-eight patients were available at debonding and 142 of them could be re-examined after 1 year (71 in the test and 71 in the placebo group). The 1-year attrition rate was 4.0%. On patient level, the prevalence of post-orthodontic WSLs (score ≥ 2) dropped by over 50% during the follow-up with no significant difference between the groups. On surface level, there were significantly fewer remaining WSLs in the test group compared with the placebo group (4.5% versus 10.4%; relative risk 0.44, 95% confidence interval 0.28–0.68). Limitations The compliance with fluoride toothpaste was not checked, and the patients’ general dentists may have instigated additional risk-based preventive measures. No cost–benefit analysis was carried out. Conclusions This follow-up study displayed a small beneficial long-term effect of fluoride varnish in reducing WSL development during treatment with FOA. Registration NCT03725020. Protocol The protocol was not published before trial commencement.

Download Full-text