Epigenetics and Fetal Metabolic Programming: A Call for Integrated Research on Larger Cohorts

Abstract The global prevalence of obesity has been rising at an alarming rate, accompanied by an increase in both childhood and maternal obesity. The concept of metabolic programming is highly topical, and in this context, describes a predisposition of offspring of obese mothers to the development of obesity independent of environmental factors. Research published in this issue of Clinical Science conducted by Litzenburger and colleagues (Clin. Sci. (Lond.) (2020) 134, 921–939) have identified sex-dependent differences in metabolic programming and identify putative signaling pathways involved in the differential phenotype of adipose tissue between males and females. Delineating the distinction between metabolically healthy and unhealthy obesity is a topic of emerging interest, and the precise nature of adipocytes are key to pathogenesis, independent of adipose tissue volume.

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Review for "miR‐148a controls metabolic programming and survival of mature CD19‐negative plasma cells in mice"

10.1002/eji.202048993/v2/review2 ◽

2020 ◽

Keyword(s):

Plasma Cells ◽

Metabolic Programming

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Targeted Gene Arrays across the Severely-Discordant growth Monochorionic Twin Placenta: Implications for Angiogenesis and Metabolic Programming

Zeitschrift für Geburtshilfe und Neonatologie ◽

10.1055/s-0031-1293261 ◽

2011 ◽

Vol 215 (S 01) ◽

Author(s):

S Schrey ◽

D Baczyk ◽

B Fitzgerald ◽

G Ryan ◽

J Kingdom ◽

...

Keyword(s):

Metabolic Programming ◽

Gene Arrays ◽

Monochorionic Twin

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Integrated Research on Statistical Mathematics and Man Power Development with Statistical Thought

The Journal of the Institute of Electrical Engineers of Japan ◽

10.1541/ieejjournal.137.206 ◽

2017 ◽

Vol 137 (4) ◽

pp. 206-209

Author(s):

Keiichiro YASUDA ◽

Junichi TSUCHIYA ◽

Kenichi TAMURA ◽

Ryuta OOSUMI ◽

Seijun MORITA

Keyword(s):

Power Development ◽

Integrated Research ◽

Statistical Mathematics

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AN APPRAISAL OF SOURCE MATERIAL FOR THE STUDY OF TARGUM MINOR PROPHETS

Journal for Semitics ◽

10.25159/1013-8471/3462 ◽

2017 ◽

Vol 24 (2) ◽

pp. 451-469

Author(s):

Gudrun Lier ◽

Anna Fransina Van Zyl

Keyword(s):

Source Material ◽

Bible Translations ◽

Integrated Research ◽

Translation Techniques ◽

Former Prophets ◽

History Of ◽

The Individual ◽

History Of Biblical Interpretation ◽

Work Done ◽

Minor Prophets

The study of Aramaic Bible translations (Targumim) continues to be a valuable source of information, not only for uncovering the history of biblical interpretation but also for providing insights for the study of linguistics and translation techniques. In comparison with work done on the Pentateuchal Targumim and Targum Former Prophets, research on the individual books of Targum Minor Prophets has been scant. By providing an overview of selected source material this review seeks (i) to provide incentives for more focussed studies in the field of Targum Minor Prophets and (ii) to motivate new integrated research approaches which are now made possible with the assistance of highly developed software programmes.

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Faculty Opinions recommendation of Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717998042.793551469 ◽

2018 ◽

Author(s):

Andrea Reboldi

Keyword(s):

T Cells ◽

Adaptive Immunity ◽

Binding Proteins ◽

Regulatory Element ◽

Effector T Cells ◽

Metabolic Programming ◽

Sterol Regulatory Element

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Faculty Opinions recommendation of The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718116512.793487247 ◽

2013 ◽

Author(s):

Leslie Berg

Keyword(s):

T Cells ◽

Transcription Factor ◽

Clonal Expansion ◽

Metabolic Programming ◽

Tcr Affinity

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The Nioghalvfjerdsfjorden glacier project, North-East Greenland: a study of ice sheet response to climatic change

Geological Survey of Denmark and Greenland Bulletin ◽

10.34194/ggub.v176.5073 ◽

1997 ◽

pp. 95-103 ◽

Cited By ~ 5

Author(s):

Henrik Højmark Thomsen ◽

Niels Reeh ◽

Ole B. Olesen ◽

Carl Egede Bøggilde ◽

Wolfgang Starzer ◽

...

Keyword(s):

Climatic Change ◽

Ice Sheet ◽

Greenland Ice Sheet ◽

East Greenland ◽

Changing Climate ◽

North East ◽

Integrated Research ◽

Research Themes ◽

Advance Research ◽

Inland Ice

NOTE: This article was published in a former series of GEUS Bulletin. Please use the original series name when citing this article, for example: Højmark Thomsen, H., Reeh, N., Olesen, O. B., Egede Bøggilde, C., Starzer, W., Weidick, A., & Higgins, A. K. (1997). The Nioghalvfjerdsfjorden glacier project, North-East Greenland: a study of ice sheet response to climatic change. Geology of Greenland Survey Bulletin, 176, 95-103. https://doi.org/10.34194/ggub.v176.5073 _______________ Glaciological research was initiated in 1996 on the floating glacier tongue filling Nioghalvfjerdsfjorden in NorthEast Greenland (Fig. 1), with the aim of acquiring a better understanding of the response of the Greenland ice sheet (Inland Ice) to changing climate, and the implications for future sea level. The research is part of a three year project (1996–98) to advance research into the basic processes that contribute to changes in the ocean volume with a changing climate. Five nations are participants in the project, which is supported by the European Community (EC) Environment and Climate Programme. The Geological Survey of Denmark and Greenland (GEUS) and the Danish Polar Center are the Danish partners in the project, both with integrated research themes concentrated on and around Nioghalvfjerdsfjorden.

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