Developing a Health Economic Model for Asians with Type 2 Diabetes Based on the Japan Diabetes Complications Study and the Japanese Elderly Diabetes Intervention Trial

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2319-PUB
Author(s):  
SHIRO TANAKA ◽  
JAKOB LANGER ◽  
TIM MORTON ◽  
LARS WILKINSON ◽  
SACHIKO TANAKA ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Health Economic ◽  
Economic Model ◽  
Diabetes Complications ◽  
Intervention Trial ◽  
Health Economic Model ◽  
Japanese Elderly ◽  
Diabetes Intervention

scholarly journals Developing a health economic model for Asians with type 2 diabetes based on the Japan Diabetes Complications Study and the Japanese Elderly Diabetes Intervention Trial

2021 ◽  
Vol 9 (1) ◽  
pp. e002177
Author(s):  
Shiro Tanaka ◽  
Jakob Langer ◽  
Tim Morton ◽  
Nicki Hoskins ◽  
Lars Wilkinson ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cost Effectiveness ◽  
Diabetes Complications ◽  
East Asian ◽  
Intervention Trial ◽  
Effectiveness Model ◽  
Japanese Elderly ◽  
Diabetes Intervention ◽  
The Cost

IntroductionCost-effectiveness analyses are becoming increasingly important in Japan following the introduction of a health technology assessment scheme. The study objective was to develop an economic model to evaluate the cost-effectiveness of two interventions for type 2 diabetes in a Japanese population.Research design and methodsThe Japan Diabetes Complications Study/Japanese Elderly Diabetes Intervention Trial risk engine (JJRE) Cost-Effectiveness Model (JJCEM) was developed, incorporating validated risk equations in Japanese patients with type 2 diabetes from the JJRE. Weibull regression models were developed for progression of the model outcomes, and a targeted literature review was performed to inform default values for utilities and costs. To illustrate outcomes, two simulated analyses were performed in younger (aged 40 years) and older (aged 80 years) Japanese populations, comparing a hypothetical treatment with placebo.ResultsThe model considers a population based on user-defined values for 11 baseline characteristic parameters and simulates rates of diabetic complications over a defined time horizon. Costs, quality-adjusted life years, and an incremental cost-effectiveness ratio are estimated. The model provides disaggregated results for two competing interventions, allowing visualization of the key drivers of cost and utility. A scatterplot of simulations and cost-effectiveness acceptability curve are generated for each analysis.ConclusionsThis is the first cost-effectiveness model for East Asian patients with type 2 diabetes, developed using Japan-specific risk equations. This population constitutes the largest share of the global population with diabetes, making this model highly relevant. The model can be used to evaluate the cost-effectiveness of anti-diabetic interventions in patients with type 2 diabetes in Japan and other East Asian populations.

scholarly journals PDB82 Development of a Health Economic Model to Compare the Prevention, Treatment and Management Strategies of Type 2 Diabetes

2011 ◽  
Vol 14 (7) ◽  
pp. A486-A487 ◽  
Author(s):  
B. Nagy ◽  
L. Nagyjanosi ◽  
S. Nagyistok ◽  
J. Józwiak-Hagymásy ◽  
Z. Dessewffy ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Health Economic ◽  
Economic Model ◽  
Management Strategies ◽  
Health Economic Model
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