scholarly journals High Prevalence of a Monogenic Cause in Han Chinese Diagnosed With Type 1 Diabetes, Partly Driven by Nonsyndromic Recessive WFS1 Mutations

Diabetes ◽  
2019 ◽  
Vol 69 (1) ◽  
pp. 121-126 ◽  
Author(s):  
Meihang Li ◽  
Sihua Wang ◽  
Kuanfeng Xu ◽  
Yang Chen ◽  
Qi Fu ◽  
...  
Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1514-P ◽  
Author(s):  
ERIC RENARD ◽  
ZSOLT BOSNYAK ◽  
FELIPE LAUAND ◽  
PAOLO POZZILLI ◽  
HIROSHI IKEGAMI ◽  
...  

2020 ◽  
Author(s):  
Matthieu Wargny ◽  
Pierre Gourdy ◽  
Lisa Ludwig ◽  
Dominique Seret-Bégué ◽  
Olivier Bourron ◽  
...  

Since the start of the COVID-19 pandemic, patients with diabetes were rapidly recognized as a high-risk population for severe disease. Indeed, a high prevalence of diabetes among patients with COVID-19 who required hospitalization has been consistently reported, reaching 33.8% in 5,700 people hospitalized for COVID-19 in New York City area (1). In addition, diabetes was associated with more than a double risk of intensive care unit (ICU) admission and more than a triple risk of death (2). However, precise data regarding the type of diabetes are scarce. We report here the clinical characteristics and early prognosis of patients with type 1 diabetes (T1D) hospitalized for COVID-19 in the nationwide multicenter observational CORONADO (CORONAvirus-SARS-CoV-2 and Diabetes Outcomes) study (3).


2020 ◽  
Vol 22 (1) ◽  
pp. 53-56 ◽  
Author(s):  
Fortunato Lombardo ◽  
Stefano Passanisi ◽  
Lucia Caminiti ◽  
Andrea Barbalace ◽  
Alessandra Marino ◽  
...  

2018 ◽  
Vol 11 (4) ◽  
pp. 273-279 ◽  
Author(s):  
Yicheng K. Bao ◽  
Lamont G. Weide ◽  
Vishwanath C. Ganesan ◽  
Ishaan Jakhar ◽  
Janet B. McGill ◽  
...  

2020 ◽  
Vol 21 (6) ◽  
pp. 1043-1049
Author(s):  
Franciska Nilsson ◽  
Jens Otto Broby Madsen ◽  
Andreas Kryger Jensen ◽  
Birthe Susanne Olsen ◽  
Jesper Johannesen

2000 ◽  
Vol 85 (11) ◽  
pp. 4182-4187 ◽  
Author(s):  
Héctor F. Escobar-Morreale ◽  
Belén Roldán ◽  
Raquel Barrio ◽  
Milagros Alonso ◽  
José Sancho ◽  
...  

The current recommendation for strict metabolic control of type 1 diabetes mellitus requires the administration of supraphysiological doses of insulin, which might result in insulin-mediated stimulation of androgen synthesis, as occurs in insulin-resistant states. At present, the prevalence of hyperandrogenic disorders in women with type 1 diabetes mellitus is unknown. Eighty-five women with type 1 diabetes mellitus were evaluated for symptoms and signs of hyperandrogenism. In 68 of the patients, several serum androgen and hormone concentrations were measured. The polycystic ovary syndrome (PCOS) was defined by the presence of menstrual dysfunction, together with clinical and/or biochemical evidence of hyperandrogenism, and exclusion of other etiologies. Eighteen healthy women, menstruating regularly, served as controls for the androgenic profiles. Thirty-three patients (38.8%) presented hyperandrogenic disorders (16 had PCOS, and 17 had hirsutism without menstrual dysfunction). Type 1 diabetic patients with PCOS presented increased serum total and free testosterone concentrations, and serum androstenedione levels, but had normal serum sex hormone-binding globulin and dehydroepiandrosterone-sulfate levels. Hirsute type 1 diabetic women without menstrual dysfunction presented normal serum androgen levels. There were no significant differences between hyperandrogenic and nonhyperandrogenic type 1 diabetes mellitus women in clinical variables such as the duration of diabetes, age at diagnosis of diabetes, conventional or intensive insulin therapy, mean daily insulin dosage, or metabolic control. In conclusion, women with type 1 diabetes mellitus have a high prevalence of hyperandrogenic disorders, including PCOS and hirsutism.


2007 ◽  
Vol 70 (5) ◽  
pp. 369-375 ◽  
Author(s):  
J.-P. Wang ◽  
Z.-G. Zhou ◽  
J. Lin ◽  
G. Huang ◽  
C. Zhang ◽  
...  

Diabetes Care ◽  
2001 ◽  
Vol 24 (3) ◽  
pp. 504-509 ◽  
Author(s):  
A. J. K. Williams ◽  
A. J. Norcross ◽  
R. J. Lock ◽  
D. J. Unsworth ◽  
E. A. M. Gale ◽  
...  

2008 ◽  
Vol 42 (5) ◽  
pp. 460-465 ◽  
Author(s):  
José María Remes-Troche ◽  
Aurelio Rios-Vaca ◽  
María Teresa Ramírez-Iglesias ◽  
Alberto Rubio-Tapia ◽  
Vicente Andrade-Zarate ◽  
...  

Diabetologia ◽  
2007 ◽  
Vol 50 (11) ◽  
pp. 2276-2279 ◽  
Author(s):  
Y. M. Cho ◽  
J. T. Kim ◽  
K. S. Ko ◽  
B. K. Koo ◽  
S. W. Yang ◽  
...  

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