1179-P: Acute Physiological Effects of Gastric Aspiration for the Treatment of Obesity

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 1179-P
Author(s):  
IDA MARIE GETHER ◽  
MARIE M. JENSEN ◽  
TINA JORSAL ◽  
CHRISTINA NEXØE-LARSEN ◽  
LÆRKE S. GASBJERG ◽  
...  
2020 ◽  
Vol 38 (Suppl. 2) ◽  
pp. 150-162 ◽  
Author(s):  
Davor Štimac ◽  
Sanja Klobučar Majanović ◽  
Andrej Belančić

Background: Conventional approaches in the management of obesity offer only a limited potential for sustained weight loss. Moreover, bariatric surgery, although momentarily being the most effective weight-loss treatment, has some serious pitfalls, such as significant morbidity rate, high substantial costs and limited patient applicability. Hence, there is a substantial need for endoscopic approaches to obesity. Summary: The aim of this article is to provide a historical overview of bariatric endoscopy in the management of obesity; moreover to selectively review and evaluate the currently available endoscopic weight-loss techniques and devices, and third to identify new directions and future prospects in this rapidly advancing field. Key Messages: Bariatric endoscopy procedures efficiently replicate some of the anatomical features and the physiological effects of the traditional weight-loss surgical approaches, while at the same time being more applicable, entirely reversible, less-invasive, safer and more cost effective. Endoscopic modalities in the treatment of obesity can be categorized into the following: restrictive procedures, malabsorptive procedures, gastric function/emptying regulation, gastric aspiration, and so on. To conclude, it is of high importance to constantly evaluate the long-term efficacy and safety of new endoscopic weight-loss techniques and devices, based on evidence-based medicine principles.


2020 ◽  
Vol 477 (7) ◽  
pp. 1261-1286 ◽  
Author(s):  
Marie Anne Richard ◽  
Hannah Pallubinsky ◽  
Denis P. Blondin

Brown adipose tissue (BAT) has long been described according to its histological features as a multilocular, lipid-containing tissue, light brown in color, that is also responsive to the cold and found especially in hibernating mammals and human infants. Its presence in both hibernators and human infants, combined with its function as a heat-generating organ, raised many questions about its role in humans. Early characterizations of the tissue in humans focused on its progressive atrophy with age and its apparent importance for cold-exposed workers. However, the use of positron emission tomography (PET) with the glucose tracer [18F]fluorodeoxyglucose ([18F]FDG) made it possible to begin characterizing the possible function of BAT in adult humans, and whether it could play a role in the prevention or treatment of obesity and type 2 diabetes (T2D). This review focuses on the in vivo functional characterization of human BAT, the methodological approaches applied to examine these features and addresses critical gaps that remain in moving the field forward. Specifically, we describe the anatomical and biomolecular features of human BAT, the modalities and applications of non-invasive tools such as PET and magnetic resonance imaging coupled with spectroscopy (MRI/MRS) to study BAT morphology and function in vivo, and finally describe the functional characteristics of human BAT that have only been possible through the development and application of such tools.


Author(s):  
D. H. Ryman ◽  
T. L. Kelly ◽  
C. E. Englund ◽  
P. Naitoh ◽  
M. Sinclair

2010 ◽  
Author(s):  
Travis Simcox ◽  
Salif Mahamane ◽  
Maura Pilotti

2001 ◽  
Vol 2 (2) ◽  
pp. 133-140 ◽  
Author(s):  
Drew A. Anderson ◽  
Jennifer R. Shapiro ◽  
Jennifer D. Lundgren

Sign in / Sign up

Export Citation Format

Share Document