scholarly journals Vitamin D Status and Glucose Homeostasis in the 1958 British Birth Cohort: The role of obesity

Diabetes Care ◽  
2006 ◽  
Vol 29 (10) ◽  
pp. 2244-2246 ◽  
Author(s):  
E. Hypponen ◽  
C. Power
Keyword(s):  
Vitamin D ◽  
Birth Cohort ◽  
Glucose Homeostasis ◽  
Vitamin D Status

scholarly journals Does vitamin D supplementation prevent SARS-CoV-2 infection in military personnel? Review of the evidence

2021 ◽  
pp. bmjmilitary-2020-001686
Author(s):  
Iain T Parsons ◽  
R M Gifford ◽  
M J Stacey ◽  
L E Lamb ◽  
M K O'Shea ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Supplementation ◽  
Vitamin D Status ◽  
Military Studies ◽  
Vitamin D Receptors ◽  
Area Of Interest ◽  
Military Populations ◽  
Tract Infections ◽  
Recruit Training

For most individuals residing in Northwestern Europe, maintaining replete vitamin D status throughout the year is unlikely without vitamin D supplementation and deficiency remains common. Military studies have investigated the association with vitamin D status, and subsequent supplementation, with the risk of stress fractures particularly during recruit training. The expression of nuclear vitamin D receptors and vitamin D metabolic enzymes in immune cells additionally provides a rationale for the potential role of vitamin D in maintaining immune homeostasis. One particular area of interest has been in the prevention of acute respiratory tract infections (ARTIs). The aims of this review were to consider the evidence of vitamin D supplementation in military populations in the prevention of ARTIs, including SARS-CoV-2 infection and consequent COVID-19 illness. The occupational/organisational importance of reducing transmission of SARS-CoV-2, especially where infected young adults may be asymptomatic, presymptomatic or paucisymptomatic, is also discussed.

scholarly journals The Potential Role of Vitamin D Enhanced Foods in Improving Vitamin D Status

Nutrients ◽  
2011 ◽  
Vol 3 (12) ◽  
pp. 1023-1041 ◽  
Author(s):  
Louise O’Mahony ◽  
Magdalena Stepien ◽  
Michael J. Gibney ◽  
Anne P. Nugent ◽  
Lorraine Brennan
Keyword(s):  
Vitamin D ◽  
Potential Role ◽  
Vitamin D Status

scholarly journals Assessment of Vitamin D Status in Patients Suffering from Uncomplicated Malaria in a Health Center in the District of Abidjan (Côte d’Ivoire)

2021 ◽  
pp. 10-17
Author(s):  
Brice Kouakou Bla ◽  
Alexis Gnogbo Bahi ◽  
Juliana Mensah-Akaki ◽  
Souleymane Méité ◽  
Françis Adou Yapo ◽  
...  
Keyword(s):  
Vitamin D ◽  
Parasite Density ◽  
Uncomplicated Malaria ◽  
Parasite Species ◽  
Complete Blood Count ◽  
Vitamin D Status ◽  
25 Oh Vitamin D ◽  
Stimulation Of

Aims: The pathophysiology of Plasmodium falciparum infection is most often associated with anemia and immune deficiency. Given the important role of vitamin D in the synthesis of hemoglobin and in the stimulation of the immune system, it would be essential to assess the vitamin D status of patients with malaria in order to improve the quality of treatment management. Methodology: A thick drop and a blood smear were used to determine parasite density and parasite species respectively. The complete blood count was performed using an automated analyzer labelled Sysmex XN 1000i. Biochemical parameters such as calcium and phosphorus were determined using the Cobas C311 Hitachi. The Vidas was used to determine the concentrations of 25 (OH) -vitamin D. Results: The results showed a decrease in 25 (OH) -vitamin D concentrations in relation to the parasite density and anemia observed in patients with uncomplicated malaria. Conclusion: Vitamin D status in patients with uncomplicated malaria could represent an essential biomarker in the monitoring of antimalarial treatment.

(205) The role of clinical pain in the association between vitamin D status and sleep quality among adults with knee osteoarthritis

2014 ◽  
Vol 15 (4) ◽  
pp. S27
Author(s):  
M. Petrov ◽  
T. Glover ◽  
B. Goodin ◽  
L. Bradley ◽  
R. Fillingim
Keyword(s):  
Vitamin D ◽  
Sleep Quality ◽  
Knee Osteoarthritis ◽  
Vitamin D Status ◽  
Clinical Pain

scholarly journals Vitamin D Status Impacts Genital Mucosal Immunity and Markers of HIV-1 Susceptibility in Women

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3176
Author(s):  
Sharon M. Anderson ◽  
Andrea R. Thurman ◽  
Neelima Chandra ◽  
Suzanne S. Jackson ◽  
Susana Asin ◽  
...  
Keyword(s):  
Vitamin D ◽  
Reproductive Tract ◽  
Serum Vitamin ◽  
Female Reproductive Tract ◽  
High Dose ◽  
Vitamin D Status ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Hiv 1

While vitamin D insufficiency is known to impact a multitude of health outcomes, including HIV-1, little is known about the role of vitamin D-mediated immune regulation in the female reproductive tract (FRT). We performed a pilot clinical study of 20 women with circulating 25(OH)D levels <62.5 nmol/L. Participants were randomized into either weekly or daily high-dose oral vitamin D supplementation groups. In addition to serum vitamin D levels, genital mucosal endpoints, including soluble mediators, immune cell populations, gene expression, and ex vivo HIV-1 infection, were assessed. While systemic vitamin D levels showed a significant increase following supplementation, these changes translated into modest effects on the cervicovaginal factors studied. Paradoxically, post-supplementation vitamin D levels were decreased in cervicovaginal fluids. Given the strong correlation between vitamin D status and HIV-1 infection and the widespread nature of vitamin D deficiency, further understanding of the role of vitamin D immunoregulation in the female reproductive tract is important.

scholarly journals Prognostic Role of Vitamin D Status and Efficacy of Vitamin D Supplementation in Cancer Patients: A Systematic Review

2011 ◽  
Vol 16 (9) ◽  
pp. 1215-1227 ◽  
Author(s):  
Consuelo Buttigliero ◽  
Chiara Monagheddu ◽  
Paola Petroni ◽  
Andrea Saini ◽  
Luigi Dogliotti ◽  
...  
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Cancer Patients ◽  
Vitamin D Supplementation ◽  
Vitamin D Status ◽  
Prognostic Role

scholarly journals The role of maternal preconception vitamin D status in human offspring sex ratio

2019 ◽  
Vol 112 (3) ◽  
pp. e26-e27
Author(s):  
Alexandra C. Purdue-Smithe ◽  
Keewan Kim ◽  
Carrie J. Nobles ◽  
Enrique F. Schisterman ◽  
Karen C. Schliep ◽  
...  
Keyword(s):  
Vitamin D ◽  
Sex Ratio ◽  
Vitamin D Status ◽  
Offspring Sex Ratio ◽  
Offspring Sex

The role of neonatal vitamin D in the association of prenatal depression with toddlers ADHD symptoms: A birth cohort study

2021 ◽  
Vol 281 ◽  
pp. 390-396
Author(s):  
Shuang-shuang Ma ◽  
Dao-min Zhu ◽  
Wan-jun Yin ◽  
Jia-hu Hao ◽  
Kun Huang ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Birth Cohort ◽  
Prenatal Depression ◽  
Birth Cohort Study ◽  
Adhd Symptoms

scholarly journals Does Vitamin D play a role in the management of Covid-19 in Brazil?

2020 ◽  
Vol 54 ◽  
pp. 53 ◽  
Author(s):  
Helena Ribeiro ◽  
Keila Valente de Souza de Santana ◽  
Sofia Lizarralde Oliver ◽  
Patricia Helen de Carvalho Rondó ◽  
Marcela Moraes Mendes ◽  
...  
Keyword(s):  
Vitamin D ◽  
Randomized Controlled Trials ◽  
Respiratory Infections ◽  
Sun Exposure ◽  
Hypovitaminosis D ◽  
Controlled Trials ◽  
Vitamin D Status ◽  
Randomized Controlled ◽  
Vitamin D Levels

The study discusses the possible role of adequate vitamin D status in plasma or serum for preventing acute respiratory infections during the Covid-19 pandemic. Our arguments respond to an article, published in Italy, that describes the high prevalence of hypovitaminosis D in older Italian women and raises the possible preventive and therapeutic role of optimal vitamin D levels. Based on literature review, we highlight the findings regarding the protective role of vitamin D for infectious diseases of the respiratory system. However, randomized controlled trials are currently lacking. Adequate vitamin D status is obtained from sun exposure and foods rich in vitamin D. Studies in Brazil have shown that hypovitaminosis D is quite common in spite of high insolation. Authors recommend ecological, epidemiological and randomized controlled trials studies to verify this hypothesis.

scholarly journals Vitamin D status and metabolism in an ovine pregnancy model: effect of long-term, high-altitude hypoxia

2016 ◽  
Vol 310 (11) ◽  
pp. E1062-E1071 ◽  
Author(s):  
Ravi Goyal ◽  
Tara L. Billings ◽  
Trina Mansour ◽  
Courtney Martin ◽  
David J. Baylink ◽  
...  
Keyword(s):  
Vitamin D ◽  
High Altitude ◽  
Plasma Levels ◽  
Vitamin D Status ◽  
Molecular Determinants ◽  
Near Term ◽  
Specific Regulation ◽  
Circulating Levels

Vitamin D status increases during healthy mammalian pregnancy, but the molecular determinants remain uncharacterized. The first objective of this study was to determine the effects of pregnancy, and the second objective was to examine the role of chronic hypoxia on vitamin D status and metabolism in an ovine model. We analyzed the plasma levels of cholecalciferol, 25-OH-D, and 1α,25-(OH)2D in nonpregnant ewes, near-term pregnant ewes, and their fetuses exposed to normoxia (low altitude) or hypoxia (high-altitude) for 100 days. Hypoxic sheep had increased circulating levels of 25-OH-D and 1α,25-(OH)2D compared with normoxic sheep. Hypoxia increases in 25-OH-D were associated with increased expression of renal 25-hydroxylases CYP2R1 and CYP2J. Pregnancy did not increase further the plasma levels of 25-OH-D, but it significantly increased those of the active metabolite, 1α,25-(OH)2D, in both normoxic and hypoxic ewes. Increased bioactivation of vitamin D correlated with increased expression of the vitamin D-activating enzyme CYP27b1 and decreased expression of the inactivating enzyme CYP24a1 in maternal kidneys and placentas. Hypoxia increased parathyroid hormone levels and further increased renal CYP27b1. Pregnancy and hypoxia decreased the expression of vitamin D receptor (VDR) in maternal kidney and lung, with opposite effects on placental VDR. We conclude that ovine pregnancy is a model of increased vitamin D status, and long-term hypoxia further improves vitamin D status due to pregnancy- and hypoxia-specific regulation of VDR and metabolic enzymes.

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