scholarly journals The Usefulness of the International Diabetes Federation and the National Cholesterol Education Program's Adult Treatment Panel III Definitions of the Metabolic Syndrome in Predicting Coronary Heart Disease in Subjects With Type 2 Diabetes

Diabetes Care ◽  
2007 ◽  
Vol 30 (5) ◽  
pp. 1206-1211 ◽  
Author(s):  
P. C. Tong ◽  
A. P. Kong ◽  
W.-Y. So ◽  
X. Yang ◽  
C.-S. Ho ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
International Diabetes Federation ◽  
Adult Treatment ◽  
Adult Treatment Panel ◽  
The Metabolic Syndrome

scholarly journals Prevalence of the metabolic syndrome diagnosed using three different definitions and risk of ischemic heart disease among Kaunas adult population

Medicina ◽  
2010 ◽  
Vol 46 (1) ◽  
pp. 61 ◽  
Author(s):  
Dalia Lukšienė ◽  
Miglė Bacevičienė ◽  
Abdonas Tamošiūnas ◽  
Liucija Černiauskienė ◽  
Lilija Margevičienė ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
International Diabetes Federation ◽  
Ischemic Heart ◽  
Adult Treatment ◽  
Adult Treatment Panel ◽  
International Diabetes Federation Definition ◽  
The Metabolic Syndrome ◽  
The World

The aim of this study was to compare the prevalence of the metabolic syndrome diagnosed using three different definitions and to evaluate its associations with ischemic heart disease in Kaunas adult population. Material and methods. Data of preventive screening carried out in Kaunas in 2001–2002 according to the MONICA study protocol were used for analysis; a total of 1336 persons aged 35–64 years (603 men and 733 women) were recruited. The metabolic syndrome was defined by the World Health Organization, Adult Treatment Panel III, and International Diabetes Federation definitions. Ischemic heart disease was diagnosed based on the following criteria: a documented history of myocardial infarction, angina pectoris, or ischemic changes on electrocardiogram. Results. The metabolic syndrome was identified for 11.3% of men and for 9.4% of women using the World Health Organization definition, for 19.4% of men and for 26.3% of women using the Adult Treatment Panel III definition, and for 30.0% of men and for 37.7% of women using the International Diabetes Federation definition. In male and female groups, the prevalence of the metabolic syndrome (irrespective of definition) significantly increased with age (P<0.05). After adjusting for age, men diagnosed with the metabolic syndrome using the International Diabetes Federation definition (OR=2.30; P=0.001) and Adult Treatment Panel III definition (OR=1.97; P=0.01) and women diagnosed with metabolic syndrome using the International Diabetes Federation definition (OR=1.50; P=0.039) had a significantly higher risk of having ischemic heart disease as compared with those without the metabolic syndrome by the same definitions. The metabolic syndrome diagnosed using the World Health Organization definition was not associated with a significant risk of ischemic heart disease in men and women. Conclusion. In Kaunas population aged 35–64 years, the highest prevalence of the metabolic syndrome was determined according to the International Diabetes Federation definition. Usage of the International Diabetes Federation and the Adult Treatment Panel III definitions in establishing diagnosis of the metabolic syndrome provides more opportunities to identify subjects with ischemic heart disease.

Possibilities of Multislice Computed Tomography in the Diagnosis of Atheroclerotic Lesions of the Main Vessels for Type 2 Diabetes and Other Variants Disorders of Carbohydrate Metabolism

2021 ◽  
Vol 65 (5) ◽  
pp. 45-50
Author(s):  
E Praskurnichiy ◽  
E Ionova ◽  
I Begunova ◽  
A Knyazev
Keyword(s):  
Computed Tomography ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Carbohydrate Metabolism ◽  
Multislice Computed Tomography ◽  
Early Stage ◽  
Laboratory Diagnostics

Purpose: Study of structural and morphological features of atherosclerotic lesions of large main vessels (carotid arteries) in type 2 diabetes mellitus. Material and methods: The study included 78 patients. Exclusion criteria: age under 40 years, pregnancy, acute infectious diseases, as well as chronic diseases within less than 2 weeks from the onset of complete clinical and laboratory remission, severe cardiac (LVEF < 30 %) and renal (blood creatinine > 300 mmol/l) insufficiency, alcohol abuse or drug dependence. There were 44 men (56.4 %) and 34 women (43.6 %) in the group surveyed. Coronary heart disease was detected in 54 (69.2 %) individuals, 24 (30.8 %) of the examined individuals had no signs of coronary heart disease; 19 (24.4 %) people had a history of stroke, 18 (23 %) people — myocardial infarction. 42 people (53.8 %) had dyscirculatory encephalopathy of various degrees, 34 (43.6 %) had hypertension, 42 patients had carbohydrate metabolism disorders, 12 (15.3 %) patients had type 2 diabetes, and 30 (38.4 %) patients had metabolic syndrome. Three groups of subjects were formed. The group of people without metabolic syndrome included 48 people (61.5 % of the total number of examined). The group of people with metabolic syndrome without type 2 diabetes included 18 individuals (23.1 % of the total number of examined). The group of people with type 2 diabetes included 12 individuals (15.4 % of the total number of examined). The examination of patients included: physical examination; laboratory diagnostics; electrocardiography; transthoracic echocardiography; multislice computed tomography with angiocontrast. Results: 78 patients were found to have different density of atherosclerotic plaques. There were no differences in volume among the groups of people surveyed. In patients with type 2 diabetes, there is a decrease in the lipid-fibrous component and an increase in the density of atherosclerotic plaque. Conclusion: Multislice computed tomography can detect various forms of vascular damage, the progression of the process, and assess the severity of structural and morphological manifestations of atherosclerosis in type 2 diabetes and metabolic syndrome at an early stage.

scholarly journals Gender Differences in Risks of Coronary Heart Disease and Stroke in Patients with Type 2 Diabetes Mellitus and Their Association with Metabolic Syndrome in China

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Mei-Fang Yao ◽  
Jie He ◽  
Xue Sun ◽  
Xiao-Li Ji ◽  
Yue Ding ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Coronary Heart Disease ◽  
Type 2 Diabetes Mellitus ◽  
Heart Disease ◽  
Stroke Risk ◽  
Chinese Women ◽  
Chd Risk

Coronary heart disease (CHD) and stroke are common complications of type 2 diabetes mellitus (T2DM). We aimed to explore the differences in the risks of CHD and stroke between Chinese women and men with T2DM and their association with metabolic syndrome (MS). This study included 1514 patients with T2DM. The Asian Guidelines of ATPIII (2005) were used for MS diagnosis, and the UKPDS risk engine was used to evaluate the 10-year CHD and stroke risks. Women had lower CHD risk (15.3% versus 26.3%), fatal CHD risk (11.8% versus 19.0%), stroke risk (8.4% versus 10.3%), and fatal stroke risk (1.4% versus 1.6%) compared with men with T2DM (p<0.05–0.001). The CHD risk (28.4% versus 22.6%, p<0.001) was significantly higher in men with MS than in those without MS. The CHD (16.2% versus 11.0%, p<0.001) and stroke risks (8.9% versus 5.8%, p<0.001) were higher in women with MS than in those without MS. In conclusion, our findings indicated that Chinese women with T2DM are less susceptible to CHD and stroke than men. Further, MS increases the risk of both these events, highlighting the need for comprehensive metabolic control in T2DM.

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